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Tytuł :
Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy.
Autorzy :
Bogan RK; School of Medicine, University of South Carolina, Columbia, SC.
Thorpy MJ; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY.
Dauvilliers Y; Sleep and Wake Disorders Centre, Department of Neurology, Gui de Chauliac Hospital, Montpellier, France.; Department of Neurology, University of Montpellier, INSERM U1061, Montpellier, France.
Partinen M; Helsinki Sleep Clinic, Vitalmed Research Center, Helsinki, Finland.
Del Rio Villegas R; Neurophysiology and Sleep Disorders Unit, Hospital Vithas Nuestra Señora de America, Madrid, Spain.
Foldvary-Schaefer N; Sleep Disorders Center, Cleveland Clinic, Cleveland, OH.
Skowronski R; Global Clinical Development, Jazz Pharmaceuticals, Inc., Palo Alto, CA.
Tang L; Biostatistics, Jazz Pharmaceuticals, Inc., Palo Alto, CA.
Skobieranda F; Global Clinical Development, Jazz Pharmaceuticals, Inc., Palo Alto, CA.
Šonka K; Department of Neurology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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Źródło :
Sleep [Sleep] 2021 Mar 12; Vol. 44 (3).
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cataplexy*/drug therapy
Narcolepsy*/drug therapy
Sodium Oxybate*/adverse effects
Sodium Oxybate*/therapeutic use
Adolescent ; Adult ; Aged ; Calcium ; Double-Blind Method ; Humans ; Magnesium ; Middle Aged ; Potassium ; Sodium ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
 
Autorzy :
Steurer J; Universitätsspital Zürich.
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Transliterated Title :
SGLT2-Hemmer verlangsamen die Abnahme der Nierenfunktion und reduzieren die Wahrscheinlichkeit kardialer Ereignisse.
Źródło :
Praxis [Praxis (Bern 1994)] 2021 Apr; Vol. 110 (5), pp. 275-276.
Typ publikacji :
Journal Article
MeSH Terms :
Sodium-Glucose Transporter 2 Inhibitors*
Humans ; Hypoglycemic Agents ; Kidney ; Sodium-Glucose Transporter 2
Czasopismo naukowe
Tytuł :
To Salt or Not to Salt? Is That a Question in Obstructive Sleep Apnea?
Autorzy :
Kasai T; Department of Cardiovascular Medicine and.; Cardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Sleep and Sleep Disordered Breathing Center, Juntendo University Hospital, Tokyo, Japan.
Peker Y; Department of Pulmonary Medicine, Koc University School of Medicine, Istanbul, Turkey.; Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Sciences, Respiratory Medicine and Allergology, Faculty of Medicine, Lund University, Lund, Sweden; and.; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
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Źródło :
Annals of the American Thoracic Society [Ann Am Thorac Soc] 2021 Mar; Vol. 18 (3), pp. 424-425.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Sleep Apnea, Obstructive*/diagnosis
Sodium*
Brazil ; Humans ; Sodium Chloride
Opinia redakcyjna
Tytuł :
Early eGFR decline after SGLT2i initiation: knowns and unknowns.
Autorzy :
Gregg LP; Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA; Section of Nephrology, Department of Medicine, Michael E. DeBakey VA Medical Center, Houston, Texas, USA; VA Health Services Research and Development Center for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.
Navaneethan SD; Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA; Section of Nephrology, Department of Medicine, Michael E. DeBakey VA Medical Center, Houston, Texas, USA; VA Health Services Research and Development Center for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA; Institute of Clinical and Translational Research, Baylor College of Medicine, Houston, Texas, USA. Electronic address: .
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Źródło :
Kidney international [Kidney Int] 2021 Mar; Vol. 99 (3), pp. 548-550.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Benzhydryl Compounds ; ErbB Receptors ; Glomerular Filtration Rate ; Glucose ; Glucosides ; Humans ; Sodium
Czasopismo naukowe
Tytuł :
Voltage-Gated Sodium Channel Blockers: Synthesis of Mexiletine Analogues and Homologues.
Autorzy :
Catalano A; Department of Pharmacy-Drug Sciences, University of Bari 'Aldo Moro', via Orabona 4, 70126 Bari, Italy.
Franchini C; Department of Pharmacy-Drug Sciences, University of Bari 'Aldo Moro', via Orabona 4, 70126 Bari, Italy.
Carocci A; Department of Pharmacy-Drug Sciences, University of Bari 'Aldo Moro', via Orabona 4, 70126 Bari, Italy.
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Źródło :
Current medicinal chemistry [Curr Med Chem] 2021; Vol. 28 (8), pp. 1535-1548.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mexiletine*/therapeutic use
Voltage-Gated Sodium Channel Blockers*/pharmacology
Voltage-Gated Sodium Channel Blockers*/therapeutic use
Anti-Arrhythmia Agents/therapeutic use ; Arrhythmias, Cardiac/drug therapy ; Humans ; Sodium Channel Blockers/pharmacology ; Sodium Channel Blockers/therapeutic use
Czasopismo naukowe
Tytuł :
Sodium intake and progression of chronic kidney disease-has the time finally come to do the impossible: a prospective randomized controlled trial?
Autorzy :
Burnier M; Service of Nephrology and Hypertension, University Hospital, Lausanne, Switzerland.; Hypertension Research Foundation, St-Légier, Switzerland.
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Źródło :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2021 Feb 20; Vol. 36 (3), pp. 381-384.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Renal Insufficiency, Chronic*/therapy
Sodium, Dietary*
Diet, Sodium-Restricted ; Humans ; Prospective Studies ; Sodium
Opinia redakcyjna
Tytuł :
Beyond lidocaine: selective voltage-gated sodium channel blockade for vaginal pain.
Autorzy :
Holland RA; Department of Neurobiology, Pittsburgh Center for Pain Research, Pittsburgh, PA, United States.
Ross SE; Department of Neurobiology, Pittsburgh Center for Pain Research, Pittsburgh, PA, United States.; Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
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Źródło :
Pain [Pain] 2021 Jan; Vol. 162 (1), pp. 1-3.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Lidocaine*
Voltage-Gated Sodium Channels*
Female ; Humans ; Nociception ; Pain/drug therapy ; Sodium/metabolism ; Sodium Channel Blockers
Raport
Tytuł :
Household Cooking and Eating out: Food Practices and Perceptions of Salt/Sodium Consumption in Costa Rica.
Autorzy :
Blanco-Metzler A; Costa Rican Institute of Research and Teaching in Nutrition and Health (INCIENSA), Tres Ríos 4-2250, Costa Rica.
Núñez-Rivas H; Costa Rican Institute of Research and Teaching in Nutrition and Health (INCIENSA), Tres Ríos 4-2250, Costa Rica.
Vega-Solano J; Costa Rican Institute of Research and Teaching in Nutrition and Health (INCIENSA), Tres Ríos 4-2250, Costa Rica.
Montero-Campos MA; Costa Rican Institute of Research and Teaching in Nutrition and Health (INCIENSA), Tres Ríos 4-2250, Costa Rica.
Benavides-Aguilar K; Costa Rican Institute of Research and Teaching in Nutrition and Health (INCIENSA), Tres Ríos 4-2250, Costa Rica.
Cubillo-Rodríguez N; Project Consultant, International Development Research Centre (IDRC), Llorente de Tibas 11303, Costa Rica.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Jan 29; Vol. 18 (3). Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cooking*
Sodium Chloride, Dietary*
Costa Rica ; Female ; Humans ; Perception ; Sodium
Czasopismo naukowe
Tytuł :
Response to: Visaria et al. Everything in moderation: Understanding the interplay between salt and sugar intake.
Autorzy :
Khitan ZJ; Internal Medicine Department, Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia, USA.
Tzamaloukas AH; Internal Medicine Department, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Shapiro JI; Internal Medicine Department, Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia, USA.
Gress TW; Internal Medicine Department, Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia, USA.; Hershel 'Woody' Williams VA Medical Center, Huntington, West Virginia, USA.
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Źródło :
Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2020 Dec; Vol. 22 (12), pp. 2387-2388. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Letter; Comment
MeSH Terms :
Hypertension*
Sodium, Dietary*
Cross-Sectional Studies ; Humans ; Nutrition Surveys ; Sodium Chloride, Dietary/adverse effects ; Sugars
Opinia redakcyjna
Tytuł :
Low-salt diet and renal safety: taken with a pinch of salt.
Autorzy :
Heyman SN; Department of Medicine, Hadassah Hebrew University Hospital, Mt Scopus, Jerusalem, Israel.
Bursztyn M; Department of Medicine, Hadassah Hebrew University Hospital, Mt Scopus, Jerusalem, Israel.
Abassi Z; Department of Physiology and Biophysics, Ruth and Bruce Rappaport Faculty of Medicine, Technion-IIT, Haifa, Israel.; Department of Laboratory Medicine, Rambam Health Care Campus, Haifa, Israel.
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Źródło :
The Journal of physiology [J Physiol] 2020 Dec; Vol. 598 (23), pp. 5299-5300. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Angiotensin II*
Diet, Sodium-Restricted*
Kidney ; Oxygen ; Receptors, Mineralocorticoid ; Sodium Chloride, Dietary/adverse effects
Czasopismo naukowe
Tytuł :
Novel Electrical Signaling: First Fast Voltage-Gated Sodium Channel Identified Outside of the Animal Kingdom.
Autorzy :
Wege S; Australian Research Council Centre of Excellence in Plant Energy Biology, Plant Research Centre, School of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, Waite Campus, Glen Osmond 5064, South Australia, Australia .
De Angeli A; Biochemistry and Plant Molecular Physiology, Université de Montpellier, Centre National de la Recherche Scientifique, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Institut Agro, Montpellier 34060, France.
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Źródło :
Plant physiology [Plant Physiol] 2020 Dec; Vol. 184 (4), pp. 1618-1619.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Eukaryota*/metabolism
Voltage-Gated Sodium Channels*/genetics
Voltage-Gated Sodium Channels*/metabolism
Animals ; Signal Transduction ; Sodium/metabolism
Czasopismo naukowe
Tytuł :
[SGLT2 inhibitors in diabetic and non-diabetic nephropathies].
Autorzy :
Scheen M; Service de néphrologie, HUG, 1211 Genève 14.
Zanchi A; Service d'endocrinologie, CHUV, 1011 Lausanne.
Martin PY; Service de néphrologie, HUG, 1211 Genève 14.
De Seigneux S; Service de néphrologie, HUG, 1211 Genève 14.
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Transliterated Title :
Inhibiteurs du SGLT2 dans les néphropathies diabétiques et non diabétiques.
Źródło :
Revue medicale suisse [Rev Med Suisse] 2021 Feb 24; Vol. 17 (727), pp. 378-382.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
Diabetic Nephropathies*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use
Humans ; Hypoglycemic Agents/therapeutic use ; Sodium-Glucose Transporter 2
Czasopismo naukowe
Tytuł :
Emerging Topics in Heart Failure: Sodium-Glucose Co-Transporter 2 Inhibitors (SGLT2i) in HF.
Autorzy :
Bocchi EA; Clínica de Insuficiência Cardíaca do Instituto do Coração (Incor) da Universidade de São Paulo, São Paulo, SP - Brasil.
Biolo A; Faculdade de Medicina da Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS - Brasil.; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS - Brasil.; Serviço de Cardiologia do Hospital Moinhos de Vento, Porto Alegre, RS - Brasil.
Moura LZ; Pontifícia Universidade Católica do Paraná, Curitiba, PR - Brasil.
Figueiredo Neto JA; Universidade Federal do Maranhão, São Luís, MA - Brasil.
Montenegro CEL; Pronto Socorro Cardiológico de Pernambuco (PROCAPE/UPE), Pernambuco, RE - Brasil.
Albuquerque DC; Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ - Brasil.; Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ - Brasil.
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Transliterated Title :
Tópicos Emergentes em Insuficiência Cardíaca: Inibidores do Cotransportador Sódio-Glicose 2 (iSGLT2) na IC.
Źródło :
Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2021 Feb; Vol. 116 (2), pp. 355-358.
Typ publikacji :
Letter
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Heart Failure*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Symporters*
Glucose ; Humans ; Sodium
Opinia redakcyjna
Tytuł :
Sodium-glucose cotransporter type 2 inhibitors: managing the small but critical risk of diabetic ketoacidosis.
Autorzy :
Meyer EJ; The Queen Elizabeth Hospital, Adelaide, SA.; University of Adelaide, Adelaide, SA.
Thiruvenkatarajan V; The Queen Elizabeth Hospital, Adelaide, SA.; University of Adelaide, Adelaide, SA.
Jesudason D; The Queen Elizabeth Hospital, Adelaide, SA.; University of Adelaide, Adelaide, SA.
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Źródło :
The Medical journal of Australia [Med J Aust] 2021 Feb; Vol. 214 (2), pp. 93-93.e1. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Letter; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Diabetic Ketoacidosis*/chemically induced
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Glucose ; Humans ; Hypoglycemic Agents/adverse effects ; Sodium
Opinia redakcyjna
Tytuł :
Therapeutic transformation for diabetic kidney disease.
Autorzy :
Tuttle KR; Providence Medical Research Center, Providence Health Care, Spokane, Washington, USA; Institute of Translational Health Sciences, Kidney Research Institute, and Nephrology Division, University of Washington, Seattle, Washington, USA. Electronic address: .
Cherney DZI; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Nephrology Division, University of Toronto, Toronto, Ontario, Canada.
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Źródło :
Kidney international [Kidney Int] 2021 Feb; Vol. 99 (2), pp. 301-303.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*
Diabetic Nephropathies*/drug therapy
Diabetic Nephropathies*/etiology
Heart Failure*
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Albuminuria/drug therapy ; Endothelin Receptor Antagonists ; Glomerular Filtration Rate ; Glucose ; Humans ; Sodium
Czasopismo naukowe
Tytuł :
The essential challenges of salt-sensitivity of blood pressure.
Autorzy :
Heinzel FR; Charité - Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, Berlin, Germany, and DZHK (German Centre for Cardiovascular Research), partner site Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353 Berlin, Germany. Electronic address: .
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Źródło :
Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2021 Feb; Vol. 151, pp. 1-2. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Hypertension*
Sodium Chloride, Dietary*/adverse effects
Blood Pressure ; Humans ; Male ; Sodium Chloride ; Vasopressins
Opinia redakcyjna
Tytuł :
Sodium-glucose cotransporter type 2 inhibitors: managing the small but critical risk of diabetic ketoacidosis.
Autorzy :
Hamblin PS; Western Health, Melbourne, VIC.; University of Melbourne, Melbourne, VIC.
Wong R; Box Hill Hospital, Melbourne, VIC.
Bach LA; Alfred Hospital, Melbourne, VIC.; Monash University, Melbourne, VIC.
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Źródło :
The Medical journal of Australia [Med J Aust] 2021 Feb; Vol. 214 (2), pp. 94-94.e1. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Letter; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Diabetic Ketoacidosis*/chemically induced
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Glucose ; Humans ; Hypoglycemic Agents/adverse effects ; Sodium
Opinia redakcyjna
Tytuł :
SGLT-2 inhibitors: A new era in managing diabetic kidney disease starts now.
Autorzy :
Taliercio JJ; Program Director, Nephrology and Hypertension Fellowship, Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic; Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Co-investigator, EMPA-KIDNEY study .
Thomas G; Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic; Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Principal Investigator, EMPA-KIDNEY study.
Nakhoul GN; Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic; Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Co-investigator, EMPA-KIDNEY study.
Vachharajani TJ; Department of Hypertension and Nephrology, Glickman Urological and Kidney Institute, Cleveland Clinic; Clinical Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Principal Investigator, EMPA-KIDNEY study.
Mehdi A; Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic; Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
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Źródło :
Cleveland Clinic journal of medicine [Cleve Clin J Med] 2020 Dec 31; Vol. 88 (1), pp. 59-63. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Diabetic Nephropathies*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use
Humans ; Hypoglycemic Agents/therapeutic use ; Sodium-Glucose Transporter 2
Opinia redakcyjna
Tytuł :
In type 2 diabetes, SGLT2 inhibitors were linked to diabetic ketoacidosis vs. DPP-4 inhibitors.
Autorzy :
Liakos A; Aristotle University Thessaloniki, Thessaloniki, Greece (A.L., A.T., E.B.).
Tsapas A; Aristotle University Thessaloniki, Thessaloniki, Greece (A.L., A.T., E.B.).
Bekiari E; Aristotle University Thessaloniki, Thessaloniki, Greece (A.L., A.T., E.B.).
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Źródło :
Annals of internal medicine [Ann Intern Med] 2020 Dec 15; Vol. 173 (12), pp. JC70.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*/drug therapy
Diabetic Ketoacidosis*/chemically induced
Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Cohort Studies ; Glucose ; Humans ; Hypoglycemic Agents/adverse effects ; Sodium
Czasopismo naukowe
Tytuł :
The Time Is Now for Sodium Glucose Co-Transporter 2 Inhibitors for Heart Failure: A Call to Overcome Clinical Inertia.
Autorzy :
Khan MS; Department of Medicine, University of Mississippi, Jackson (M.S.K., J.B.).
Butler J; Department of Medicine, University of Mississippi, Jackson (M.S.K., J.B.).
Greene SJ; Division of Cardiology, Duke University School of Medicine, Durham, NC (S.J.G.).; Duke Clinical Research Institute, Durham, NC (S.J.G.).
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Źródło :
Circulation. Heart failure [Circ Heart Fail] 2020 Dec; Vol. 13 (12), pp. e008030. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Heart Failure*/diagnosis
Heart Failure*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Symporters*
Benzhydryl Compounds ; Glucose ; Glucosides ; Humans ; Sodium
Opinia redakcyjna

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