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Wyszukujesz frazę ""SOLID-phase synthesis"" wg kryterium: Temat


Tytuł :
Design and validation of a frugal, automated, solid-phase peptide synthesizer.
Autorzy :
Kallmyer NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Rider NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Reuel NF; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 19; Vol. 15 (8), pp. e0237473. Date of Electronic Publication: 2020 Aug 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acid Sequence ; Automation ; Cell-Penetrating Peptides/chemical synthesis ; Cell-Penetrating Peptides/chemistry ; Equipment Design ; Fluorometry ; Nanostructures/chemistry ; Oxidation-Reduction ; Peptides/chemistry ; Solid-Phase Synthesis Techniques/economics ; Solid-Phase Synthesis Techniques/instrumentation
Czasopismo naukowe
Tytuł :
Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2.
Autorzy :
Vanhoutte R; Department of Cellular and Molecular Medicine, Laboratory of Chemical Biology, KU Leuven, Herestr. 49, 3000 Leuven, Belgium.
van de Plassche MAT; Department of Cellular and Molecular Medicine, Laboratory of Chemical Biology, KU Leuven, Herestr. 49, 3000 Leuven, Belgium.
Verhelst SHL; Department of Cellular and Molecular Medicine, Laboratory of Chemical Biology, KU Leuven, Herestr. 49, 3000 Leuven, Belgium.; Leibniz Institute for Analytical Sciences ISAS, e.V., Otto-Hahn-Str. 6b, 44227 Dortmund, Germany.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Oct 22; Vol. 63 (20), pp. 11845-11853. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
Enzyme Inhibitors/*pharmacology
Molecular Probes/*pharmacology
Thiolester Hydrolases/*antagonists & inhibitors
Animals ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Humans ; Mice ; Models, Molecular ; Molecular Probes/chemical synthesis ; Molecular Probes/chemistry ; Molecular Structure ; Structure-Activity Relationship ; Thiolester Hydrolases/metabolism
Czasopismo naukowe
Tytuł :
Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy.
Autorzy :
Paciaroni NG; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA. .
Ndungu JM
Kodadek T
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Apr 30; Vol. 56 (34), pp. 4656-4659. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Library*
Solid-Phase Synthesis Techniques*
Aldehydes/*chemistry
Czasopismo naukowe
Tytuł :
Calculating Resin Functionalization in Solid-Phase Peptide Synthesis Using a Standardized Method based on Fmoc Determination.
Autorzy :
Al Musaimi O; Peptide Science Laboratory, School of Chemistry and Physics , University of KwaZulu-Natal , Durban 4001 , South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences , University of KwaZulu-Natal , Durban 4041 , South Africa.
Basso A; Purolite , Llantrisant Business Park , Llantrisant , CF72 8LF , United Kingdom.
de la Torre BG; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences , University of KwaZulu-Natal , Durban 4041 , South Africa.
Albericio F; Peptide Science Laboratory, School of Chemistry and Physics , University of KwaZulu-Natal , Durban 4001 , South Africa.; CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Department of Organic Chemistry , University of Barcelona , 08028 Barcelona , Spain.
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Źródło :
ACS combinatorial science [ACS Comb Sci] 2019 Nov 11; Vol. 21 (11), pp. 717-721. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acids/chemistry ; Fluorenes/chemistry ; Reference Standards ; Resins, Synthetic/chemistry ; Solid-Phase Synthesis Techniques/standards
Czasopismo naukowe
Tytuł :
4-Methyltrityl-Protected Pyrrole and Imidazole Building Blocks for Solid Phase Synthesis of DNA-Binding Polyamides.
Autorzy :
Heinrich B; Fachbereich Chemie , Philipps-Universität Marburg , Hans-Meerwein-Straße 4 , 35043 Marburg , Germany.
Vázquez O; Fachbereich Chemie , Philipps-Universität Marburg , Hans-Meerwein-Straße 4 , 35043 Marburg , Germany.
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Źródło :
Organic letters [Org Lett] 2020 Jan 17; Vol. 22 (2), pp. 533-536. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
DNA/*chemistry
Imidazoles/*chemistry
Nylons/*chemical synthesis
Pyrroles/*chemistry
Binding Sites ; Molecular Structure ; Nylons/chemistry
Czasopismo naukowe
Tytuł :
Synthesis of Phosphoramidite Monomers Equipped with Complementary Bases for Solid-Phase DNA Oligomerization.
Autorzy :
Romero-Pérez S; Nanostructured Molecular Systems and Materials Group, Departamento de Química Orgánica , Universidad Autónoma de Madrid , 28049 Madrid , Spain.; NanoBiotechnology Research Group , Instituto IMDEA Nanociencia , 28049 Madrid , Spain.
López-Martín I; Nanostructured Molecular Systems and Materials Group, Departamento de Química Orgánica , Universidad Autónoma de Madrid , 28049 Madrid , Spain.
Martos-Maldonado MC; Nanostructured Molecular Systems and Materials Group, Departamento de Química Orgánica , Universidad Autónoma de Madrid , 28049 Madrid , Spain.
Somoza Á; NanoBiotechnology Research Group , Instituto IMDEA Nanociencia , 28049 Madrid , Spain.
González-Rodríguez D; Nanostructured Molecular Systems and Materials Group, Departamento de Química Orgánica , Universidad Autónoma de Madrid , 28049 Madrid , Spain.; Institute for Advanced Research in Chemical Sciences (IAdChem) , Universidad Autónoma de Madrid , 28049 Madrid , Spain.
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Źródło :
Organic letters [Org Lett] 2020 Jan 03; Vol. 22 (1), pp. 41-45. Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
DNA/*chemistry
Organophosphorus Compounds/*chemical synthesis
Molecular Structure ; Organophosphorus Compounds/chemistry
Czasopismo naukowe
Tytuł :
Solid-Phase Synthesis of Phosphate/Boranophosphate Chimeric DNAs Using the H -Phosphonate- H -Boranophosphonate Method.
Autorzy :
Sato K; Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences , Tokyo University of Science , 2641 Yamazaki , Noda , Chiba 278-8510 , Japan.
Imai H; Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences , Tokyo University of Science , 2641 Yamazaki , Noda , Chiba 278-8510 , Japan.
Shuto T; Department of Medical Genome Sciences, Graduate School of Frontier Sciences , The University of Tokyo , Bioscience Building 702, 5-1-5 Kashiwanoha , Kashiwa , Chiba 277-8562 , Japan.
Hara RI; Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences , Tokyo University of Science , 2641 Yamazaki , Noda , Chiba 278-8510 , Japan.; Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences , Tokyo Medical and Dental University , 1-5-45 Yushima , Bunkyo-ku , Tokyo 113-8519 , Japan.
Wada T; Department of Medicinal and Life Sciences, Faculty of Pharmaceutical Sciences , Tokyo University of Science , 2641 Yamazaki , Noda , Chiba 278-8510 , Japan.
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Źródło :
The Journal of organic chemistry [J Org Chem] 2019 Dec 06; Vol. 84 (23), pp. 15032-15041. Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
Boranes/*chemistry
DNA/*chemical synthesis
Phosphates/*chemistry
Carbohydrate Conformation ; DNA/chemistry
Czasopismo naukowe
Tytuł :
Deprotection Strategies for Thioimidates during Fmoc Solid-Phase Peptide Synthesis: A Safe Route to Thioamides.
Autorzy :
Camacho LA 3rd; Department of Chemistry , Iowa State University , Ames , Iowa 50011 , United States.
Nguyen YH; Department of Chemistry , Iowa State University , Ames , Iowa 50011 , United States.
Turner J; Department of Chemistry , Iowa State University , Ames , Iowa 50011 , United States.
VanVeller B; Department of Chemistry , Iowa State University , Ames , Iowa 50011 , United States.
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Źródło :
The Journal of organic chemistry [J Org Chem] 2019 Dec 06; Vol. 84 (23), pp. 15309-15314. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Solid-Phase Synthesis Techniques*
Imides/*chemistry
Peptides/*chemical synthesis
Thioamides/*chemistry
Molecular Conformation ; Peptides/chemistry
Czasopismo naukowe
Tytuł :
Chemical synthesis of N-glycosylated insulin-like androgenic gland factor from the freshwater prawn Macrobrachium rosenbergii.
Autorzy :
Katayama H; Department of Applied Biochemistry, School of Engineering, Tokai University, Hiratsuka, Japan.
Nagasawa H; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2019 Nov; Vol. 25 (11), pp. e3215. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji :
Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Androgens/*chemical synthesis
Palaemonidae/*chemistry
Peptides/*chemical synthesis
Androgens/chemistry ; Animals ; Fresh Water ; Insulin/analogs & derivatives ; Insulin/chemistry ; Molecular Structure ; Peptides/chemistry
Czasopismo naukowe
Tytuł :
Complete synthesis of the bicyclic ring of a mutacin analog with orthogonally protected lanthionine via solid-phase intracyclization.
Autorzy :
Kirichenko K; Oragenics, Department of Research and Development, Oragenics, Inc., Alachua, Florida, U.S.A.; SynQuest Laboratories, Inc., Alachua, Florida, U.S.A.
Hillman JD; Oragenics, Department of Research and Development, Oragenics, Inc., Alachua, Florida, U.S.A.
Handfield M; Oragenics, Department of Research and Development, Oragenics, Inc., Alachua, Florida, U.S.A.
Park JH; Oragenics, Department of Research and Development, Oragenics, Inc., Alachua, Florida, U.S.A.
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2019 Nov; Vol. 25 (11), pp. e3214.
Typ publikacji :
Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Alanine/*analogs & derivatives
Bacteriocins/*chemical synthesis
Sulfides/*chemistry
Alanine/chemistry ; Bacteriocins/chemistry ; Molecular Conformation
Czasopismo naukowe
Tytuł :
A novel and cost-effective methodology for enhanced production of industrially valuable alkaline xylano-pectinolytic enzymes cocktail in short solid-state fermentation cycle.
Autorzy :
Agrawal S; Department of Biotechnology, Kurukshetra University, Kurukshetra, India.
Varghese LM; Department of Biotechnology, Kurukshetra University, Kurukshetra, India.
Mahajan R; Department of Biotechnology, Kurukshetra University, Kurukshetra, India.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2019 Nov; Vol. 35 (6), pp. e2872. Date of Electronic Publication: 2019 Jul 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fermentation*
Solid-Phase Synthesis Techniques*
Enzymes/*biosynthesis
Xylosidases/*biosynthesis
Enzymes/chemistry ; Hydrogen-Ion Concentration ; Pectins/pharmacology ; Polygalacturonase/biosynthesis ; Polygalacturonase/chemistry ; Polysaccharide-Lyases/biosynthesis ; Polysaccharide-Lyases/chemistry ; Temperature ; Xylans/pharmacology ; Xylosidases/chemistry ; Xylosidases/classification
Czasopismo naukowe
Tytuł :
Solid-Phase Chemical Synthesis of Stable Isotope-Labeled RNA to Aid Structure and Dynamics Studies by NMR Spectroscopy.
Autorzy :
Becette O; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. .
Olenginski LT; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. .
Dayie TK; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 Sep 25; Vol. 24 (19). Date of Electronic Publication: 2019 Sep 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Isotope Labeling*
Molecular Dynamics Simulation*
Nucleic Acid Conformation*
Solid-Phase Synthesis Techniques*
RNA/*chemistry
Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; RNA/chemical synthesis
Czasopismo naukowe
Tytuł :
Facile removal of 4-methoxybenzyl protecting group from selenocysteine.
Autorzy :
Jenny KA; Department of Chemistry, Discovery Hall, University of Vermont, Burlington, Vermont.
Ste Marie EJ; Department of Chemistry, Discovery Hall, University of Vermont, Burlington, Vermont.; Department of Biochemistry, University of Vermont, Burlington, Vermont.
Mose G; Department of Biochemistry, University of Vermont, Burlington, Vermont.
Ruggles EL; Department of Chemistry, Discovery Hall, University of Vermont, Burlington, Vermont.
Hondal RJ; Department of Chemistry, Discovery Hall, University of Vermont, Burlington, Vermont.; Department of Biochemistry, University of Vermont, Burlington, Vermont.
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2019 Oct; Vol. 25 (10), pp. e3209. Date of Electronic Publication: 2019 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Peptides/*chemical synthesis
Peptides/*chemistry
Selenocysteine/*chemistry
Amino Acid Sequence
Czasopismo naukowe
Tytuł :
Isocyanide Multicomponent Reactions on Solid-Phase-Coupled DNA Oligonucleotides for Encoded Library Synthesis.
Autorzy :
Kunig VBK; Faculty of Chemistry and Chemical Biology , TU Dortmund University , Otto-Hahn-Straße 6 , 44227 Dortmund , Germany.
Ehrt C; Faculty of Chemistry and Chemical Biology , TU Dortmund University , Otto-Hahn-Straße 6 , 44227 Dortmund , Germany.
Dömling A; Drug Design , University of Groningen , Deusinglaan 1 , 7313 AV Groningen , The Netherlands.
Brunschweiger A; Faculty of Chemistry and Chemical Biology , TU Dortmund University , Otto-Hahn-Straße 6 , 44227 Dortmund , Germany.
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Źródło :
Organic letters [Org Lett] 2019 Sep 20; Vol. 21 (18), pp. 7238-7243. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
Cyanides/*chemistry
DNA/*chemistry
Oligonucleotides/*chemistry
Combinatorial Chemistry Techniques ; Molecular Structure
Czasopismo naukowe
Tytuł :
A Strategy To Prepare Peptide Heterodimers in the Solid Phase with an Acid-Labile Linker.
Autorzy :
Wang G; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
Chen T; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
Peng T; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
Zhang S; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
Wang J; College of Engineering , Peking University , Beijing 100871 , P.R. China.
Wen X; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
Yang X; Beijing institute of Lifeomics , Beijing 102206 , P.R. China.
Wang L; Beijing institute of Radiation Medicine , Beijing 100850 , P.R. China.
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Źródło :
Organic letters [Org Lett] 2019 Sep 20; Vol. 21 (18), pp. 7351-7355. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
Peptides/*chemical synthesis
Hydrogen-Ion Concentration ; Molecular Structure ; Peptides/chemistry ; Protein Conformation
Czasopismo naukowe
Tytuł :
A Bottom-Up Approach To Preserve Thioamide Residue Stereochemistry during Fmoc Solid-Phase Peptide Synthesis.
Autorzy :
Camacho LA 3rd; Department of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
Lampkin BJ; Department of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
VanVeller B; Department of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
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Źródło :
Organic letters [Org Lett] 2019 Sep 06; Vol. 21 (17), pp. 7015-7018. Date of Electronic Publication: 2019 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Solid-Phase Synthesis Techniques*
Peptides/*chemical synthesis
Thioamides/*chemistry
Molecular Structure ; Peptides/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Chemical methods for the modification of RNA.
Autorzy :
Flamme M; Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France; Sorbonne Université, Collège doctoral, F-75005 Paris, France.
McKenzie LK; Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France.
Sarac I; Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France.
Hollenstein M; Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France. Electronic address: .
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Źródło :
Methods (San Diego, Calif.) [Methods] 2019 May 15; Vol. 161, pp. 64-82. Date of Electronic Publication: 2019 Mar 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Aptamers, Nucleotide/*chemical synthesis
Aptamers, Nucleotide/*genetics
RNA/*chemical synthesis
RNA/*genetics
Solid-Phase Synthesis Techniques/*methods
Animals ; Humans ; Oligonucleotides/chemical synthesis ; Oligonucleotides/genetics ; Solid-Phase Synthesis Techniques/trends
Czasopismo naukowe
Tytuł :
Identification of osteogenic progenitor cell-targeted peptides that augment bone formation.
Autorzy :
Jiang M; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.; Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, 200025, Shanghai, China.
Liu R; Department of Biochemistry and Molecular Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Liu L; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Kot A; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Liu X; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Xiao W; Department of Biochemistry and Molecular Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Jia J; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Li Y; Department of Biochemistry and Molecular Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Lam KS; Department of Biochemistry and Molecular Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA.
Yao W; Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, CA, 95817, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 27; Vol. 11 (1), pp. 4278. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Anabolic Agents/*pharmacology
Fractures, Bone/*drug therapy
Osteogenesis/*drug effects
Peptides/*pharmacology
Stem Cells/*drug effects
Anabolic Agents/chemistry ; Animals ; Calcification, Physiologic/drug effects ; Cell Differentiation/drug effects ; Cell Differentiation/physiology ; Cells, Cultured ; Female ; Fractures, Bone/pathology ; Humans ; Male ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Orchiectomy ; Osteogenesis/physiology ; Ovariectomy ; Peptides/chemistry ; Peptides/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Solid-Phase Synthesis Techniques ; Stem Cells/cytology
Czasopismo naukowe
Tytuł :
The aspartimide problem persists: Fluorenylmethyloxycarbonyl-solid-phase peptide synthesis (Fmoc-SPPS) chain termination due to formation of N-terminal piperazine-2,5-diones.
Autorzy :
Samson D; Bachem AG, Hauptstrasse 144, CH-4416, Bubendorf, Switzerland.
Rentsch D; Swiss Federal Laboratories for Materials Science and Technology (EMPA), Laboratory for Functional Polymers, Überlandstrasse 129, CH-8600, Dübendorf, Switzerland.
Minuth M; Bachem AG, Hauptstrasse 144, CH-4416, Bubendorf, Switzerland.
Meier T; Bachem AG, Hauptstrasse 144, CH-4416, Bubendorf, Switzerland.
Loidl G; Bachem AG, Hauptstrasse 144, CH-4416, Bubendorf, Switzerland.
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2019 Jul; Vol. 25 (7), pp. e3193.
Typ publikacji :
Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Amino Acids/*chemistry
Aspartic Acid/*analogs & derivatives
Fluorenes/*chemistry
Peptides/*chemical synthesis
Piperazines/*chemical synthesis
Amino Acid Sequence ; Aspartic Acid/chemistry ; Molecular Structure ; Peptides/chemistry ; Piperazines/chemistry
Czasopismo naukowe
Tytuł :
On-Bead Peptoid Dimerization Induced by Incorporation of Glycosylated Bridging Units in Submonomer Solid-Phase Approach to Glycopeptoids.
Autorzy :
Comegna D; Institute of Biostructures and Bioimaging-CNR , Via Mezzocannone 16 , 80134 Naples , Italy.
Del Gatto A; Institute of Biostructures and Bioimaging-CNR , Via Mezzocannone 16 , 80134 Naples , Italy.; Interdepartmental Center of Bioactive Peptide , University of Naples Federico II , Via Mezzocannone 16 , 80134 Naples , Italy.
Saviano M; Interdepartmental Center of Bioactive Peptide , University of Naples Federico II , Via Mezzocannone 16 , 80134 Naples , Italy.; Institute of Crystallography-CNR , Via Amendola 122/O , 70126 Bari , Italy.
Zaccaro L; Institute of Biostructures and Bioimaging-CNR , Via Mezzocannone 16 , 80134 Naples , Italy.; Interdepartmental Center of Bioactive Peptide , University of Naples Federico II , Via Mezzocannone 16 , 80134 Naples , Italy.
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Źródło :
Organic letters [Org Lett] 2019 Jun 21; Vol. 21 (12), pp. 4454-4458. Date of Electronic Publication: 2019 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid-Phase Synthesis Techniques*
Peptoids/*chemical synthesis
Dimerization ; Glycosylation ; Peptoids/analogs & derivatives ; Peptoids/chemistry ; Protein Conformation
Czasopismo naukowe

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