Temat: "STAT2 Transcription Factor" - OpacWWW

Skocz do pozycji: 21.

Tytuł:: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
Autorzy:: Toth K; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Lee SR; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, United States of America.
Ying B; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Spencer JF; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Tollefson AE; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Sagartz JE; Department of Comparative Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.
Kong IK; Department of Animal Science, Division of Applied Life Science and Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, Republic of Korea.
Wang Z; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, United States of America.
Wold WS; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2015 Aug 20; Vol. 11 (8), pp. e1005084. Date of Electronic Publication: 2015 Aug 20 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Disease Models, Animal*
Adenoviridae Infections/*immunology
Adenoviruses, Human/*pathogenicity
Interferon Type I/*immunology
STAT2 Transcription Factor/*deficiency
Adenoviridae Infections/pathology ; Adenoviruses, Human/immunology ; Animals ; Animals, Genetically Modified ; Cell Line, Tumor ; Cricetinae ; Flow Cytometry ; Gene Knockout Techniques ; Humans ; Mesocricetus ; Reverse Transcriptase Polymerase Chain Reaction ; STAT2 Transcription Factor/immunology

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Skocz do pozycji: 22.

Tytuł:: Identification of a Set of Genes Improving Survival Prediction in Kidney Renal Clear Cell Carcinoma through Integrative Reanalysis of Transcriptomic Data.
Autorzy:: Ruan B; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Feng X; Department of Obstetrics and Gynecology, The Third People's Hospital of Linyi, Linyi, 276000 Shandong Province, China.
Chen X; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.
Dong Z; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Wang Q; Department of Oncology, Affiliated Hospital of Qingdao University, Qingdao, 266000 Shandong Province, China.
Xu K; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Tian J; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Liu J; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Chen Z; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Shi W; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.
Wang M; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.
Qian L; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.
Ding Q; Medical Research Center, Xi'an No. 3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710016 Shaanxi Province, China.; The College of Life Sciences, Northwest University, Xi'an, 710069 Shaanxi Province, China.; Hubei Yicanhealth Co., Ltd., Wuhan, 430070 Hubei Province, China.; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, 430070 Hubei Province, China.; Pokaż więcej
Źródło:: Disease markers [Dis Markers] 2020 Oct 13; Vol. 2020, pp. 8824717. Date of Electronic Publication: 2020 Oct 13 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Renal Cell/*genetics
Carcinoma, Renal Cell/*mortality
Kidney Neoplasms/*genetics
Kidney Neoplasms/*mortality
Aged ; Biomarkers, Tumor/genetics ; Carcinoma, Renal Cell/pathology ; Computational Biology/methods ; Cyclin-Dependent Kinases/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Kidney Neoplasms/pathology ; Male ; Membrane Glycoproteins/genetics ; Middle Aged ; Nerve Tissue Proteins/genetics ; Prognosis ; Proportional Hazards Models ; STAT2 Transcription Factor/genetics

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Skocz do pozycji: 23.

Tytuł:: ADAR1 Suppresses Interferon Signaling in Gastric Cancer Cells by MicroRNA-302a-Mediated IRF9/STAT1 Regulation.
Autorzy:: Jiang L; Department of Biomedical Sciences, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Park MJ; Department of Biomedical Sciences, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Cho CJ; Department of Biomedical Sciences, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Lee K; Department of Biomedical Sciences, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Jung MK; Department of Convergence Medicine, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Pack CG; Department of Convergence Medicine, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Myung SJ; Department of Gastroenterology, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.
Chang S; Department of Biomedical Sciences, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.; Department of Physiology, College of Medicine, Asan Medical Center, University of Ulsan, Seoul 05505, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 27; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Deaminase/*genetics
Interferon-Stimulated Gene Factor 3, gamma Subunit/*metabolism
Interferons/*metabolism
MicroRNAs/*genetics
RNA-Binding Proteins/*genetics
STAT2 Transcription Factor/*metabolism
Stomach Neoplasms/*genetics
3' Untranslated Regions ; Adaptor Proteins, Signal Transducing/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Interferon-Stimulated Gene Factor 3, gamma Subunit/genetics ; RNA Editing ; Receptor, Interferon alpha-beta/metabolism ; Signal Transduction ; Stomach Neoplasms/metabolism

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Skocz do pozycji: 24.

Tytuł:: A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus.
Autorzy:: Li Y; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Higgs RE; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Hoffman RW; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Dow ER; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Liu X; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Petri M; Hopkins Lupus Center, John Hopkins University, Baltimore, Maryland, United States of America.
Wallace DJ; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.
Dörner T; Charité University Hospitals, Berlin, Germany.
Eastwood BJ; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Miller BB; Eli Lilly and Company, Indianapolis, Indiana, United States of America.
Liu Y; Eli Lilly and Company, Indianapolis, Indiana, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Dec 02; Vol. 14 (12), pp. e0225651. Date of Electronic Publication: 2019 Dec 02 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Genetic*
Gene Regulatory Networks/*immunology
Lupus Erythematosus, Systemic/*genetics
Signal Transduction/*genetics
Algorithms ; Bayes Theorem ; Clinical Trials, Phase III as Topic ; Computer Simulation ; Data Mining ; Datasets as Topic ; Gene Expression Profiling ; Humans ; Janus Kinase 2/immunology ; Janus Kinase 2/metabolism ; Linear Models ; Lupus Erythematosus, Systemic/drug therapy ; Lupus Erythematosus, Systemic/immunology ; Oligonucleotide Array Sequence Analysis ; Randomized Controlled Trials as Topic ; STAT1 Transcription Factor/immunology ; STAT1 Transcription Factor/metabolism ; STAT2 Transcription Factor/immunology ; STAT2 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology

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Skocz do pozycji: 25.

Tytuł:: Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.
Autorzy:: Kobayashi T; Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.
Shimabukuro-Demoto S; Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.
Tsutsui H; Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.
Toyama-Sorimachi N; Department of Molecular Immunology and Inflammation, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2019 Nov 15; Vol. 17 (11), pp. e3000530. Date of Electronic Publication: 2019 Nov 15 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anaphylaxis/*immunology
Interferon Type I/*physiology
Mast Cells/*immunology
Secretory Vesicles/*metabolism
Animals ; Cells, Cultured ; Histamine/blood ; Homeostasis ; Mice ; Receptor, Interferon alpha-beta/genetics ; STAT1 Transcription Factor/genetics ; STAT1 Transcription Factor/physiology ; STAT2 Transcription Factor/genetics ; STAT2 Transcription Factor/physiology ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/physiology ; Signal Transduction

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Skocz do pozycji: 26.

Tytuł:: The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9.
Autorzy:: Mariani MK; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.
Dasmeh P; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.; Centre Robert Cedergren en Bioinformatique et Génomique, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Fortin A; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.
Caron E; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.
Kalamujic M; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.
Harrison AN; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.; Department of Microbiology and Immunology, McGill University, Montréal, QC H3A 2B4, Canada.
Hotea DI; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Kasumba DM; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Cervantes-Ortiz SL; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.; Department of Microbiology, Infectiology and Immunology, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Mukawera E; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada.
Serohijos AWR; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.; Centre Robert Cedergren en Bioinformatique et Génomique, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Grandvaux N; CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada. .; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada. .; Pokaż więcej
Źródło:: Cells [Cells] 2019 Aug 17; Vol. 8 (8). Date of Electronic Publication: 2019 Aug 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interferon-Stimulated Gene Factor 3, gamma Subunit/*metabolism
Interferon-beta/*physiology
STAT2 Transcription Factor/*metabolism
Tumor Necrosis Factor-alpha/*physiology
Vesicular Stomatitis/*immunology
Vesicular stomatitis Indiana virus/*immunology
A549 Cells ; Humans

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Skocz do pozycji: 27.

Tytuł:: Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V-ATPase.
Autorzy:: Johnson HM; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA.
Noon-Song E; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA.
Ahmed CM; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2019 May 28; Vol. 2019, pp. 4143604. Date of Electronic Publication: 2019 May 28 (Print Publication: 2019).
Typ publikacji:: Journal Article; Review
MeSH Terms:: Steroids/*metabolism
Vacuolar Proton-Translocating ATPases/*metabolism
Animals ; Humans ; Interferons/metabolism ; STAT Transcription Factors/metabolism ; STAT2 Transcription Factor/metabolism ; Signal Transduction ; TYK2 Kinase/metabolism

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Skocz do pozycji: 28.

Tytuł:: STAT2 hypomorphic mutant mice display impaired dendritic cell development and antiviral response.
Autorzy:: Chen LS; Graduate Institute of Immunology, National Taiwan University College of Medicine, 1 Jen-Ai Road, Section 1, Rm 513, Taipei 100, Taiwan, Republic of China. />Wei PC
Liu T
Kao CH
Pai LM
Lee CK; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2009 Feb 19; Vol. 16, pp. 22. Date of Electronic Publication: 2009 Feb 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutation*
STAT2 Transcription Factor*/genetics
STAT2 Transcription Factor*/metabolism
Dendritic Cells/*physiology
Immune System Phenomena/*physiology
Interferon-alpha/*immunology
Interferon-gamma/*immunology
Viruses/*metabolism
Animals ; Cells, Cultured ; DNA Mutational Analysis ; Dendritic Cells/cytology ; Female ; Fibroblasts/cytology ; Fibroblasts/physiology ; Humans ; Introns ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pedigree ; RNA Splicing ; Viruses/pathogenicity

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Skocz do pozycji: 29.

Tytuł:: The C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining Stat1 in perinuclear aggregates at the late endosome.
Autorzy:: Schomacker H; RNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Hebner RM
Boonyaratanakornkit J
Surman S
Amaro-Carambot E
Collins PL
Schmidt AC; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e28382. Date of Electronic Publication: 2012 Feb 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Nucleus/*metabolism
Endosomes/*metabolism
Interferons/*metabolism
STAT1 Transcription Factor/*metabolism
STAT2 Transcription Factor/*metabolism
Viral Proteins/*metabolism
Animals ; Blotting, Western ; Chlorocebus aethiops ; Humans ; Immunoprecipitation ; Phosphorylation ; Protein Transport ; STAT1 Transcription Factor/antagonists & inhibitors ; STAT2 Transcription Factor/antagonists & inhibitors ; Signal Transduction ; Vero Cells ; Virus Replication

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Skocz do pozycji: 30.

Tytuł:: p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.
Autorzy:: Testoni B; Laboratory of Gene Expression, Fondazione A. Cesalpino, Rome, Italy. />Schinzari V
Guerrieri F
Gerbal-Chaloin S
Blandino G
Levrero M; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2011 Jun 09; Vol. 30 (23), pp. 2670-8. Date of Electronic Publication: 2011 Mar 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Binding Proteins/*metabolism
Interferon-alpha/*pharmacology
Nuclear Proteins/*metabolism
STAT2 Transcription Factor/*metabolism
Transcription Factors/*metabolism
Tumor Suppressor Proteins/*metabolism
Binding Sites/genetics ; Blotting, Western ; Cell Line, Tumor ; Cells, Cultured ; Chromatin Immunoprecipitation ; Colonic Neoplasms/genetics ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; DNA-Binding Proteins/genetics ; Enhancer of Zeste Homolog 2 Protein ; Female ; Hep G2 Cells ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Histones/metabolism ; Humans ; Interferon-Stimulated Gene Factor 3, gamma Subunit/genetics ; Interferon-Stimulated Gene Factor 3, gamma Subunit/metabolism ; Interferon-alpha/metabolism ; Methylation/drug effects ; Middle Aged ; Mutation ; Nuclear Proteins/genetics ; Polycomb Repressive Complex 2 ; Promoter Regions, Genetic/genetics ; Protein Binding/drug effects ; RNA Interference ; Reverse Transcriptase Polymerase Chain Reaction ; STAT1 Transcription Factor/genetics ; STAT1 Transcription Factor/metabolism ; STAT2 Transcription Factor/genetics ; Transcription Factors/genetics ; Tumor Protein p73 ; Tumor Suppressor Proteins/genetics

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Skocz do pozycji: 31.

Tytuł:: PCBP2 enhances the antiviral activity of IFN-α against HCV by stabilizing the mRNA of STAT1 and STAT2.
Autorzy:: Xin Z; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Han W
Zhao Z
Xia Q
Yin B
Yuan J
Peng X; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011; Vol. 6 (10), pp. e25419. Date of Electronic Publication: 2011 Oct 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiviral Agents/*pharmacology
Hepacivirus/*drug effects
Interferon-alpha/*pharmacology
RNA Stability/*drug effects
RNA-Binding Proteins/*metabolism
STAT1 Transcription Factor/*genetics
STAT2 Transcription Factor/*genetics
3' Untranslated Regions/genetics ; Base Sequence ; Binding Sites ; Cell Line, Tumor ; Down-Regulation/drug effects ; Genome, Viral/genetics ; Hepacivirus/genetics ; Humans ; Models, Biological ; Molecular Sequence Data ; Protein Binding/drug effects ; Replicon/genetics ; STAT1 Transcription Factor/metabolism ; STAT2 Transcription Factor/metabolism ; Up-Regulation/drug effects ; Viral Nonstructural Proteins/metabolism

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Skocz do pozycji: 32.

Tytuł:: STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium.
Autorzy:: Wilson RP; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Tursi SA; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Rapsinski GJ; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Medeiros NJ; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Le LS; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Kotredes KP; Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Patel S; Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Liverani E; Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Sun S; Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Zhu W; Department of Microbiology, University of Texas Southwestern Medical Center Dallas, TX, United States of America.
Kilpatrick L; Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Winter SE; Department of Microbiology, University of Texas Southwestern Medical Center Dallas, TX, United States of America.
Gamero AM; Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.
Tükel Ç; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2019 Apr 22; Vol. 15 (4), pp. e1007745. Date of Electronic Publication: 2019 Apr 22 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Dysbiosis/*immunology
Gastroenteritis/*immunology
Inflammation/*immunology
Interferon Type I/*immunology
STAT2 Transcription Factor/*physiology
Salmonella Infections/*immunology
Salmonella typhimurium/*immunology
Animals ; Cells, Cultured ; Dysbiosis/metabolism ; Dysbiosis/pathology ; Female ; Gastroenteritis/metabolism ; Gastroenteritis/microbiology ; Gastroenteritis/pathology ; Inflammation/metabolism ; Inflammation/microbiology ; Inflammation/pathology ; Interferon Type I/metabolism ; Intestines/immunology ; Intestines/microbiology ; Intestines/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neutrophils/immunology ; Neutrophils/metabolism ; Neutrophils/microbiology ; Neutrophils/pathology ; STAT1 Transcription Factor/physiology ; Salmonella Infections/metabolism ; Salmonella Infections/microbiology ; Salmonella Infections/pathology

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Skocz do pozycji: 33.

Tytuł:: Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha.
Autorzy:: Schubert C; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Allhoff M; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Tillmann S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Maié T; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Costa IG; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Lipka DB; Regulation of Cellular Differentiation Group, Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Schemionek M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Feldberg K; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Baumeister J; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Chatain N; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.
Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany. .; Pokaż więcej
Źródło:: Journal of hematology & oncology [J Hematol Oncol] 2019 Apr 02; Vol. 12 (1), pp. 36. Date of Electronic Publication: 2019 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fusion Proteins, bcr-abl/*metabolism
Interferon-alpha/*metabolism
Janus Kinase 2/*genetics
STAT1 Transcription Factor/*genetics
STAT2 Transcription Factor/*genetics
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Humans

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Skocz do pozycji: 34.

Tytuł:: Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3.
Autorzy:: Qin C; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhang R; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Lang Y; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Shao A; Department of Microbiology and Immunology, College of Biological Sciences, China Agricultural University, Beijing, China.
Xu A; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Feng W; Department of Microbiology and Immunology, College of Biological Sciences, China Agricultural University, Beijing, China.
Han J; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang M; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
He W; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yu C; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.
Tang J; State Key Laboratory of Agrobiotechnology and College of Veterinary Medicine, China Agricultural University, Beijing, China.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2019 Jan 25; Vol. 15 (1), pp. e1007559. Date of Electronic Publication: 2019 Jan 25 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interferons/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Repressor Proteins/*metabolism
Tumor Suppressor Proteins/*metabolism
Viral Proteins/*metabolism
Alphaherpesvirinae/metabolism ; Alphaherpesvirinae/pathogenicity ; Animals ; Antiviral Agents/pharmacology ; Cell Line ; China ; Herpesvirus 1, Human/metabolism ; Herpesvirus 1, Suid/metabolism ; Humans ; Immunity, Innate/drug effects ; Interferon Type I/immunology ; Interferon-Stimulated Gene Factor 3, alpha Subunit/metabolism ; Interferon-alpha/metabolism ; Interferons/immunology ; Mice ; Mice, Inbred BALB C ; Phosphorylation ; Protein Serine-Threonine Kinases/genetics ; Repressor Proteins/physiology ; Response Elements ; STAT1 Transcription Factor/metabolism ; STAT2 Transcription Factor/metabolism ; Signal Transduction/immunology ; Tumor Suppressor Proteins/physiology ; Viral Proteins/genetics ; Virus Diseases/genetics

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Skocz do pozycji: 35.

Tytuł:: Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters.
Autorzy:: Siddharthan V; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .; Institute for Antiviral Research, and Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .
Miao J; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .; Department of Pathology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450066, China. .
Van Wettere AJ; Utah Veterinary Diagnostics Laboratory, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .
Li R; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .
Wu H; SAB Biotherapeutics, Sioux Falls, SD 57104, USA. .
Sullivan E; SAB Biotherapeutics, Sioux Falls, SD 57104, USA. .
Jiao J; SAB Biotherapeutics, Sioux Falls, SD 57104, USA. .
Hooper JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA. .
Safronetz D; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E, Canada. .
Morrey JD; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .; Institute for Antiviral Research, and Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .
Julander JG; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .; Institute for Antiviral Research, and Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .
Wang Z; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 5600 Old Main Hill, Logan, UT 84322, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2019 Jan 22; Vol. 11 (2). Date of Electronic Publication: 2019 Jan 22.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Immunization, Passive*
Antibodies, Neutralizing/*therapeutic use
Antibodies, Viral/*therapeutic use
STAT2 Transcription Factor/*genetics
Zika Virus Infection/*prevention & control
Zika Virus Infection/*therapy
Animals ; Animals, Genetically Modified ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Cattle ; Cricetinae ; Disease Models, Animal ; Female ; Gene Knockout Techniques ; Humans ; Male ; Testis/pathology ; Testis/virology ; Zika Virus

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Skocz do pozycji: 36.

Tytuł:: Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.
Autorzy:: Poat B; Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA-70112, USA.
Hazari S
Chandra PK
Gunduz F
Alvarez X
Balart LA
Garry RF
Dash S; Pokaż więcej
Źródło:: Virology journal [Virol J] 2010 Oct 12; Vol. 7, pp. 265. Date of Electronic Publication: 2010 Oct 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Signal Transduction*
Virus Replication*
Hepacivirus/*immunology
Hepacivirus/*physiology
Interferon-Stimulated Gene Factor 3, gamma Subunit/*immunology
STAT1 Transcription Factor/*immunology
STAT2 Transcription Factor/*immunology
Cell Line ; Genes, Reporter ; Histocompatibility Antigens Class I/metabolism ; Humans ; Interferon-Stimulated Gene Factor 3, gamma Subunit/genetics ; Interferon-alpha/immunology ; Luciferases/genetics ; Luciferases/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology ; STAT1 Transcription Factor/genetics ; STAT2 Transcription Factor/genetics

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Skocz do pozycji: 37.

Tytuł:: Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis.
Autorzy:: Manoochehrabadi S; Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arsang-Jang S; Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran.
Mazdeh M; Neurophysiology Center, Hamadan University of Medical Sciences, Hamadan, Iran.; Department of Neurology, Hamadan University of Medical Sciences, Hamadan, Iran.
Inoko H; Department of Molecular Life Science, Tokai University School of Medicine, Isehara, Japan.; Genodive Pharma Inc., Atsugi, Japan.
Sayad A; Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Taheri M; Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Urogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: Human antibodies [Hum Antibodies] 2019; Vol. 27 (2), pp. 91-98.
Typ publikacji:: Journal Article
MeSH Terms:: Multiple Sclerosis/*blood
Multiple Sclerosis/*genetics
RNA, Messenger/*blood
RNA, Messenger/*genetics
STAT1 Transcription Factor/*genetics
STAT2 Transcription Factor/*genetics
STAT3 Transcription Factor/*genetics
Adolescent ; Adult ; Case-Control Studies ; Down-Regulation/genetics ; Female ; Gene Expression/genetics ; Humans ; Male ; Middle Aged ; Signal Transduction/genetics ; Up-Regulation/genetics ; Young Adult

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Skocz do pozycji: 38.

Tytuł:: Suppression of Type I Interferon Signaling by Flavivirus NS5.
Autorzy:: Thurmond S; Department of Microbiology and Plant Pathology, University of California, Riverside, Riverside, CA 92521, USA. .; Graduate Program in Cell, Molecular and Developmental Biology, University of California, Riverside, Riverside, CA 92521, USA. .
Wang B; Department of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA. .
Song J; Department of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA. .
Hai R; Department of Microbiology and Plant Pathology, University of California, Riverside, Riverside, CA 92521, USA. .; Graduate Program in Cell, Molecular and Developmental Biology, University of California, Riverside, Riverside, CA 92521, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2018 Dec 14; Vol. 10 (12). Date of Electronic Publication: 2018 Dec 14.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Signal Transduction*
Flavivirus/*immunology
Interferon Type I/*immunology
Viral Nonstructural Proteins/*immunology
Animals ; Chlorocebus aethiops ; Flavivirus/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate ; Interferon Type I/antagonists & inhibitors ; Mice ; STAT2 Transcription Factor/genetics ; Vero Cells

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Skocz do pozycji: 39.

Tytuł:: Pathogenesis of Rift Valley Fever Virus Aerosol Infection in STAT2 Knockout Hamsters.
Autorzy:: Hickerson BT; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .
Westover JB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .
Van Wettere AJ; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .; Utah Veterinary Diagnostic Laboratory, Logan, UT 84341, USA. .
Rigas JD; Utah Veterinary Diagnostic Laboratory, Logan, UT 84341, USA. .; IDEXX Laboratories, Mukilteo, WA 98275, USA. .
Miao J; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .; Sino-British Research Center for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, School of Basic Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China. .
Conrad BL; Utah Veterinary Diagnostic Laboratory, Logan, UT 84341, USA. .
Motter NE; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .
Wang Z; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .
Gowen BB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2018 Nov 19; Vol. 10 (11). Date of Electronic Publication: 2018 Nov 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Aerosols*
Disease Models, Animal*
Rift Valley Fever/*pathology
STAT2 Transcription Factor/*deficiency
Administration, Inhalation ; Animal Structures/pathology ; Animal Structures/virology ; Animals ; Blood Chemical Analysis ; Cricetinae ; Gene Knockout Techniques ; Leukocytes/immunology ; Time Factors

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Skocz do pozycji: 40.

Tytuł:: Analysis of differentially expressed genes and the promoters in bovine endometrium throughout estrus cycle and early pregnancy.
Autorzy:: Musavi SAA; Department of Animal and Marine Bio Resource Sciences, Graduate School Kyushu University, Fukuoka, Japan.; Department of Animal Husbandry, Agriculture Faculty, Balkh University, Mazar-e-Sharif, Afghanistan.
Yamashita S; Department of Animal and Marine Bio Resource Sciences, Graduate School Kyushu University, Fukuoka, Japan.
Fujihara T; Department of Animal and Marine Bio Resource Sciences, Graduate School Kyushu University, Fukuoka, Japan.
Masaka H; Department of Animal and Marine Bio Resource Sciences, Graduate School Kyushu University, Fukuoka, Japan.
Islam MR; Department of Genetics and Animal Breeding, Faculty of Veterinary and Animal Science, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Kim S; Laboratory of Molecular Gene Technics, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Gotoh T; Laboratory of Meat Science, Graduate School of Agriculture, Kagoshima University, Kagoshima, Japan.
Kawahara M; Department of Animal Science, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Tashiro K; Laboratory of Molecular Gene Technics, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Yamauchi N; Department of Animal and Marine Bio Resource Sciences, Graduate School Kyushu University, Fukuoka, Japan.; Pokaż więcej
Źródło:: Animal science journal = Nihon chikusan Gakkaiho [Anim Sci J] 2018 Nov; Vol. 89 (11), pp. 1609-1621. Date of Electronic Publication: 2018 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression*
Cattle/*genetics
Cattle/*physiology
Endometrium/*metabolism
Endometrium/*physiology
Estrus/*genetics
Estrus/*metabolism
Pregnancy, Animal/*genetics
Pregnancy, Animal/*metabolism
Promoter Regions, Genetic/*genetics
Animals ; DNA, Complementary/analysis ; DNA, Complementary/isolation & purification ; Female ; High-Throughput Nucleotide Sequencing ; Homeodomain Proteins ; Interferon Regulatory Factors ; Pregnancy ; RNA/analysis ; RNA/isolation & purification ; STAT1 Transcription Factor ; STAT2 Transcription Factor ; Transcription Factors

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