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Tytuł :
Melatonin Treatment Alters Biological and Immunomodulatory Properties of Human Dental Pulp Mesenchymal Stem Cells via Augmented Transforming Growth Factor Beta Secretion.
Autorzy :
García-Bernal D; Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria-Arrixaca, Murcia, Spain; Internal Medicine Department, Faculty of Medicine, University of Murcia, Murcia, Spain.
López-García S; Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria-Arrixaca, Murcia, Spain.
Sanz JL; Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Guerrero-Gironés J; School of Dentistry, Faculty of Medicine, University of Murcia, Murcia, Spain.
García-Navarro EM; Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria-Arrixaca, Murcia, Spain.
Moraleda JM; Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria-Arrixaca, Murcia, Spain; Internal Medicine Department, Faculty of Medicine, University of Murcia, Murcia, Spain.
Forner L; Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Rodríguez-Lozano FJ; Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria-Arrixaca, Murcia, Spain; School of Dentistry, Faculty of Medicine, University of Murcia, Murcia, Spain. Electronic address: .
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Źródło :
Journal of endodontics [J Endod] 2021 Mar; Vol. 47 (3), pp. 424-435. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Melatonin*/pharmacology
Mesenchymal Stem Cells*
Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Dental Pulp ; Humans ; Osteogenesis ; Stem Cells ; Transforming Growth Factor beta
Czasopismo naukowe
Tytuł :
[Research advances on mechanism of exosomes derived from adipose derived stem cells in the treatment of chronic wounds].
Autorzy :
Tang LJ; The First Clinical College of Dalian Medical University, Dalian 116044, China.
Zhang XW; Department of Burns and Plastic Surgery of Subei People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Jin JJ; Department of Burns and Plastic Surgery of Subei People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Li XM; The First Clinical College of Dalian Medical University, Dalian 116044, China.
Xu G; Department of Burns and Plastic Surgery of Subei People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
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Źródło :
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns [Zhonghua Shao Shang Za Zhi] 2021 Feb 20; Vol. 37 (2), pp. 191-195.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Exosomes*
Mesenchymal Stem Cells*
Adipocytes ; Adipose Tissue ; Stem Cells ; Wound Healing
Czasopismo naukowe
Tytuł :
[Research Advance of on the Support Effect of Adipose Tissue-Derived Stem Cell on Hematopoietic Stem/Progenitor Cell--Review].
Autorzy :
Zhou R; Ningxia Medical University,Yinchuan 750004, Ningxia Hui Autonomous Region, China.
Zheng B; Department of Hematology, The General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China,E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Feb; Vol. 29 (1), pp. 301-305.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hematopoietic Stem Cell Transplantation*
Mesenchymal Stem Cells*
Adipose Tissue ; Bone Marrow Cells ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Hematopoietic Stem Cells ; Humans
Czasopismo naukowe
Tytuł :
Immunocytochemical characterization of primary teeth pulp stem cells from three stages of resorption in serum-free medium.
Autorzy :
Alansary M; Faculty of Dentistry, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
Drummond B; Faculty of Dentistry, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
Coates D; Faculty of Dentistry, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
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Źródło :
Dental traumatology : official publication of International Association for Dental Traumatology [Dent Traumatol] 2021 Feb; Vol. 37 (1), pp. 90-102. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Dental Pulp*
Mesenchymal Stem Cells*
Cell Differentiation ; Cells, Cultured ; Humans ; Stem Cells ; Tooth, Deciduous
Czasopismo naukowe
Tytuł :
SFRP2 promotes stem cells from apical papilla-mediated periodontal tissue regeneration in miniature pig.
Autorzy :
Li G; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.; Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, China.
Han N; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.; Department of Periodontology, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Yang H; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zhang X; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.; Department of Periodontology, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Cao Y; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Cao Y; Department of General Dentistry, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Shi R; Department of Endodontics, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Wang S; Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, China.; Department of Biochemistry and Molecular Biology, Capital Medical University School of Basic Medical Sciences, Beijing, China.
Fan Z; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
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Źródło :
Journal of oral rehabilitation [J Oral Rehabil] 2020 Nov; Vol. 47 Suppl 1, pp. 12-18. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Gingival Recession*
Mesenchymal Stem Cells*
Periodontitis*
Animals ; Humans ; Infant, Newborn ; Membrane Proteins/genetics ; Stem Cells ; Swine ; Swine, Miniature ; Transfection
Czasopismo naukowe
Tytuł :
Less is more: Corroborating a genomic biomarker identifying human bone marrow multipotent stromal cells with high scalability.
Autorzy :
Burns JS; Department of Endocrinology, University Hospital of Odense, Odense, Denmark & Molecular Endocrinology Unit (KMEB), Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.; Faculty of Medical Engineering, University Politehnica of Bucharest, Bucharest, Romania.
Kassem M; Department of Endocrinology, University Hospital of Odense, Odense, Denmark & Molecular Endocrinology Unit (KMEB), Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Cellular and Molecular Medicine, Danish Stem Cell Center (DanStem), University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Stem cells (Dayton, Ohio) [Stem Cells] 2020 Nov; Vol. 38 (11), pp. E5-E6. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Mesenchymal Stem Cells*
Biomarkers ; Bone Marrow ; Bone Marrow Cells ; Genomics ; Humans ; Multipotent Stem Cells
Raport
Tytuł :
Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids.
Autorzy :
Tiwari SK; Division of Genetics, Department of Pediatrics, Program in Immunology, Institute for Genomic Medicine, University of California San Diego, 9500 Gilman Drive MC 0762, La Jolla, CA 92093, USA.
Wang S; Division of Genetics, Department of Pediatrics, Program in Immunology, Institute for Genomic Medicine, University of California San Diego, 9500 Gilman Drive MC 0762, La Jolla, CA 92093, USA.
Smith D; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0762, La Jolla, CA 92093, USA.
Carlin AF; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0762, La Jolla, CA 92093, USA.
Rana TM; Division of Genetics, Department of Pediatrics, Program in Immunology, Institute for Genomic Medicine, University of California San Diego, 9500 Gilman Drive MC 0762, La Jolla, CA 92093, USA. Electronic address: .
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Źródło :
Stem cell reports [Stem Cell Reports] 2021 Mar 09; Vol. 16 (3), pp. 437-445. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*virology
COVID-19/*virology
Induced Pluripotent Stem Cells/*virology
Lung/*virology
Neural Stem Cells/*virology
Organoids/*virology
SARS-CoV-2/*pathogenicity
Apoptosis/physiology ; Brain/metabolism ; COVID-19/metabolism ; Cells, Cultured ; Complement System Proteins/metabolism ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Inflammation/metabolism ; Inflammation/virology ; Lung/metabolism ; Neural Stem Cells/metabolism ; Neurons/metabolism ; Neurons/virology ; Organoids/metabolism ; Serine Endopeptidases/metabolism ; Signal Transduction/physiology ; Stem Cells/metabolism ; Stem Cells/virology
Czasopismo naukowe
Tytuł :
Key human embryo stage mimicked in the lab.
Autorzy :
Leslie M
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Źródło :
Science (New York, N.Y.) [Science] 2021 Mar 19; Vol. 371 (6535), pp. 1189.
Typ publikacji :
Wiadomości
MeSH Terms :
Embryonic Development*
Blastocyst/*physiology
Induced Pluripotent Stem Cells/*cytology
Induced Pluripotent Stem Cells/*physiology
Blastocyst/cytology ; Cells, Cultured ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/physiology ; Humans
Periodyk
Tytuł :
Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus?
Autorzy :
Riedel RN; Instituto de Química Biológica (IQUIBICEN), CONICET- Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria Pabellón 2, 4° piso, 1428, Buenos Aires, Argentina.
Pérez-Pérez A; Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Hospital Universitario Virgen Macarena, Facultad de Medicina, Universidad de Sevilla, Avenida Sánchez Pizjuán 4, 41009, Sevilla, España.
Sánchez-Margalet V; Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Hospital Universitario Virgen Macarena, Facultad de Medicina, Universidad de Sevilla, Avenida Sánchez Pizjuán 4, 41009, Sevilla, España.
Varone CL; Instituto de Química Biológica (IQUIBICEN), CONICET- Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria Pabellón 2, 4° piso, 1428, Buenos Aires, Argentina.
Maymó JL; Instituto de Química Biológica (IQUIBICEN), CONICET- Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria Pabellón 2, 4° piso, 1428, Buenos Aires, Argentina. .
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Źródło :
Stem cell research & therapy [Stem Cell Res Ther] 2021 Mar 01; Vol. 12 (1), pp. 155. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mesenchymal Stem Cell Transplantation*
Amnion/*cytology
COVID-19/*therapy
Stem Cells/*cytology
Clinical Trials as Topic ; Female ; Humans ; Inflammation ; Mesenchymal Stem Cells/cytology ; Placenta/cytology ; Pregnancy ; Risk
Czasopismo naukowe
Tytuł :
A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.
Autorzy :
Vitrac A; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Pons S; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Balkota M; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Lemière N; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Raïs C; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.; Collège Doctoral, Sorbonne Université, Paris, France.
Bourgeois JP; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Maskos U; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Bourgeron T; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Cloëz-Tayarani I; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 07; Vol. 10 (1), pp. 13315. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Neural Stem Cells*/metabolism
Neural Stem Cells*/pathology
Neural Stem Cells*/transplantation
Stem Cell Transplantation*
Autism Spectrum Disorder/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Nerve Tissue Proteins/*metabolism
Pyramidal Cells/*metabolism
Transplantation Chimera/*metabolism
Animals ; Autism Spectrum Disorder/genetics ; Autism Spectrum Disorder/pathology ; Cell Line ; Disease Models, Animal ; Heterografts ; Humans ; Induced Pluripotent Stem Cells/pathology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Nerve Tissue Proteins/genetics ; Pyramidal Cells/pathology ; Transplantation Chimera/genetics
Czasopismo naukowe
Tytuł :
Identification of novel Taz isoforms and functional comparison in pluripotency maintenance of mouse embryonic stem cells.
Autorzy :
Xu Y; Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing 400038, China.
Liu L; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Wang X; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Huang Y; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Cheng Y; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Zhang J; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Wang J; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Tian Y; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Xiong J; Experimental Center of Basic Medicine, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China.
Yang Y; Experimental Center of Basic Medicine, College of Basic Medical Sciences, Army Medical University, Chongqing 400038, China.
Ren B; Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing 400038, China.
Wu W; Thoracic Surgery Department, Southwest Hospital, the First Hospital Affiliated to Army Medical University, Chongqing 400038, China.
He P; Cardiac Surgery Department, Southwest Hospital, the First Hospital Affiliated to Army Medical University, Chongqing 400038, China.
Zhang Y; Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing 400038, China.
Zhao B; Department of Physiology, Army Medical University, Chongqing 400038, China.
Wang J; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Yu M; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Wang J; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Jian R; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China.
Liu Y; Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing 400038, China. Electronic address: .
Ruan Y; Laboratory of Stem Cell & Developmental Biology, Department of Histology and Embryology, Army Medical University, Chongqing 400038, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Mar 20; Vol. 773, pp. 145383. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing/*genetics
DNA-Binding Proteins/*genetics
Mouse Embryonic Stem Cells/*metabolism
Trans-Activators/*genetics
Transcription Factors/*genetics
Animals ; Apoptosis/genetics ; Cell Differentiation/genetics ; Gene Expression Regulation/genetics ; Mice ; Pluripotent Stem Cells/metabolism ; Protein Isoforms/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Autorzy :
Velten L; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. .; Universitat Pompeu Fabra (UPF), Barcelona, Spain. .
Story BA; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; Swiss Federal Institute of Technology (ETH) Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.
Hernández-Malmierca P; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.
Raffel S; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
Leonce DR; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
Milbank J; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
Paulsen M; European Molecular Biology Laboratory (EMBL), Flow Cytometry Core Facility, Heidelberg, Germany.
Demir A; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
Szu-Tu C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Frömel R; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Lutz C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
Nowak D; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Jann JC; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Pabst C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.; Molecular Medicine Partnership Unit (MMPU), University of Heidelberg and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Boch T; Swiss Federal Institute of Technology (ETH) Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Hofmann WK; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Müller-Tidow C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.
Trumpp A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.
Haas S; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Charité-Universitätsmedizin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Steinmetz LM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany. .; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. .; Stanford Genome Technology Center, Palo Alto, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 01; Vol. 12 (1), pp. 1366. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Single-Cell Analysis*
Clone Cells/*pathology
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*pathology
Neoplastic Stem Cells/*metabolism
Neoplastic Stem Cells/*pathology
Transcriptome/*genetics
Biomarkers, Tumor/genetics ; Bone Marrow/pathology ; Cell Differentiation ; Gene Expression Regulation, Leukemic ; Genome ; Hematopoietic Stem Cells/pathology ; Humans ; K562 Cells ; Mitochondria/genetics ; Mutation/genetics
Czasopismo naukowe
Tytuł :
Exosomes from adipose-derived stem cells and application to skin wound healing.
Autorzy :
An Y; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Lin S; Hearing Ctr, Department of Otolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China.
Tan X; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Zhu S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Nie F; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Zhen Y; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Gu L; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Zhang C; Institute of Systems Biomedicine, Peking University, Beijing, China.
Wang B; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Wei W; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, China.
Li D; Department of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Wu J; Hearing Ctr, Department of Otolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China.
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Źródło :
Cell proliferation [Cell Prolif] 2021 Mar; Vol. 54 (3), pp. e12993. Date of Electronic Publication: 2021 Jan 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adipocytes/*cytology
Exosomes/*metabolism
Skin/*cytology
Stem Cells/*cytology
Wound Healing/*physiology
Animals ; Exosomes/transplantation ; Humans ; Mesenchymal Stem Cells/cytology
Czasopismo naukowe
Tytuł :
The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation.
Autorzy :
Ji Z; Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
Li Y; Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
Liu SX; Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
Sharrocks AD; Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Feb 22; Vol. 49 (3), pp. 1345-1363.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcriptional Activation*
Cell Differentiation/*genetics
Embryonic Stem Cells/*metabolism
Forkhead Transcription Factors/*metabolism
Cell Lineage/genetics ; Cells, Cultured ; Chromatin/metabolism ; Embryonic Stem Cells/cytology ; Endoderm/cytology ; Enhancer Elements, Genetic ; Histone Code ; Humans ; Mesoderm/cytology ; Neural Stem Cells/metabolism ; Neurogenesis/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages.
Autorzy :
Hall-Roberts H; James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford; Alzheimer's Research UK Oxford Drug Discovery Institute, Nuffield Department of Medicine Research Building, University of Oxford; UK Dementia Research Institute, Cardiff University; .
Di Daniel E; Alzheimer's Research UK Oxford Drug Discovery Institute, Nuffield Department of Medicine Research Building, University of Oxford.
James WS; James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford.
Davis JB; Alzheimer's Research UK Oxford Drug Discovery Institute, Nuffield Department of Medicine Research Building, University of Oxford.
Cowley SA; James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2021 Feb 14 (168). Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Phagocytosis*
Biological Assay/*methods
Induced Pluripotent Stem Cells/*metabolism
Macrophages/*metabolism
Neuroblastoma/*pathology
Animals ; Cell Death ; Cell Line, Tumor ; Data Analysis ; Fluorescent Dyes/chemistry ; Human Embryonic Stem Cells/cytology ; Humans ; Hydrogen-Ion Concentration ; Induced Pluripotent Stem Cells/cytology ; Quality Control ; Reproducibility of Results ; Time-Lapse Imaging
Czasopismo naukowe
Tytuł :
Metabolic control of DNA methylation in naive pluripotent cells.
Autorzy :
Betto RM; Department of Molecular Medicine, Medical School, University of Padua, Padua, Italy.
Diamante L; Department of Molecular Medicine, Medical School, University of Padua, Padua, Italy.
Perrera V; Department of Molecular Medicine, Medical School, University of Padua, Padua, Italy.; Neuroscience Sector, International School for Advanced Studies (SISSA), Trieste, Italy.
Audano M; Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, Milan, Italy.
Rapelli S; Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy.
Lauria A; Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy.
Incarnato D; Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, the Netherlands.; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, the Netherlands.
Arboit M; Department of Molecular Medicine, Medical School, University of Padua, Padua, Italy.
Pedretti S; Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, Milan, Italy.
Rigoni G; Department of Biology, University of Padua, Padua, Italy.; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Guerineau V; Université Paris-Saclay, Institut de Chimie des Substances Naturelles, CNRS, Gif-sur-Yvette, France.
Touboul D; Université Paris-Saclay, Institut de Chimie des Substances Naturelles, CNRS, Gif-sur-Yvette, France.
Stirparo GG; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Lohoff T; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
Boroviak T; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.
Grumati P; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Soriano ME; Department of Biology, University of Padua, Padua, Italy.
Nichols J; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Mitro N; Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, Milan, Italy. .
Oliviero S; Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy. .; Italian Institute for Genomic Medicine (IIGM), Candiolo, Italy. .
Martello G; Department of Molecular Medicine, Medical School, University of Padua, Padua, Italy. .; Department of Biology, University of Padua, Padua, Italy. .
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Źródło :
Nature genetics [Nat Genet] 2021 Feb; Vol. 53 (2), pp. 215-229. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blastocyst/*physiology
DNA Methylation/*physiology
Embryonic Stem Cells/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Cell Differentiation ; Cells, Cultured ; DNA (Cytosine-5-)-Methyltransferases/genetics ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Embryonic Stem Cells/physiology ; Gene Expression Regulation ; Histones/metabolism ; Ketoglutaric Acids/metabolism ; Leukemia Inhibitory Factor/metabolism ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Otx Transcription Factors/genetics ; Otx Transcription Factors/metabolism ; Pluripotent Stem Cells/metabolism ; Promoter Regions, Genetic ; STAT3 Transcription Factor/genetics
Czasopismo naukowe
Tytuł :
A Transcriptome-Based Drug Discovery Paradigm for Neurodevelopmental Disorders.
Autorzy :
Dhindsa RS; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University Irving Medical Center, New York, NY, USA.
Zoghbi AW; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Psychiatry, Columbia University Irving Medical Center and New York State Psychiatric Institute, New York, NY, USA.
Krizay DK; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY, USA.
Vasavda C; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY, USA.
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Źródło :
Annals of neurology [Ann Neurol] 2021 Feb; Vol. 89 (2), pp. 199-211. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation/*genetics
Neural Stem Cells/*drug effects
Neurodevelopmental Disorders/*drug therapy
Neurons/*drug effects
Transcriptome/*drug effects
Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Anticonvulsants/pharmacology ; Antidepressive Agents/pharmacology ; Antipsychotic Agents/pharmacology ; Carbamazepine/pharmacology ; Computer Simulation ; Drug Discovery ; Epirizole/pharmacology ; Gene Expression Profiling ; Humans ; Induced Pluripotent Stem Cells ; MCF-7 Cells ; Mice ; Naloxone/pharmacology ; Narcotic Antagonists/pharmacology ; Neural Stem Cells/metabolism ; Neurodevelopmental Disorders/genetics ; Neurons/metabolism ; PC-3 Cells ; Perphenazine/pharmacology ; Primary Cell Culture ; RNA-Seq ; Risperidone/pharmacology ; Single-Cell Analysis ; Trazodone/pharmacology ; Trimipramine/pharmacology
Czasopismo naukowe
Tytuł :
TLR3 ligation affects differentiation and stemness properties of gingival mesenchymal stem/progenitor cells.
Autorzy :
Mekhemar M; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht's University, Kiel, Germany.
Tölle J; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht's University, Kiel, Germany.
Dörfer C; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht's University, Kiel, Germany.
Fawzy El-Sayed K; Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht's University, Kiel, Germany.; Oral Medicine and Periodontology Department, Faculty of Oral and Dental Medicine, Cairo University, Cairo, Egypt.
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Źródło :
Journal of clinical periodontology [J Clin Periodontol] 2020 Aug; Vol. 47 (8), pp. 991-1005. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mesenchymal Stem Cells*
Toll-Like Receptor 3*
Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Stem Cells
Czasopismo naukowe
Tytuł :
Aluminium affects neurospheres at human in vivo relevant concentrations.
Autorzy :
van Thriel C; Leibniz Research Centre for Working Environment and Human Factors, Ardeystr. 67, 44139, Dortmund, Germany. .
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Źródło :
Archives of toxicology [Arch Toxicol] 2020 Oct; Vol. 94 (10), pp. 3601-3602. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Letter; Comment
MeSH Terms :
Aluminum*/toxicity
Neural Stem Cells*
Embryonic Stem Cells ; Humans ; Phenotype
Opinia redakcyjna
Tytuł :
General requirements for stem cells.
Autorzy :
Hao J; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Ma A; Chinese Society for Stem Cell Research, Shanghai, China.; China National Institute of Standardization, Beijing, China.; Beijing Technology and Business University, Beijing, China.
Wang L; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Cao J; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Chen S; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Wang L; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Fu B; Chinese Society for Stem Cell Research, Shanghai, China.; China National Institute of Metrology, Beijing, China.
Zhou J; Chinese Society for Stem Cell Research, Shanghai, China.
Pei X; Chinese Society for Stem Cell Research, Shanghai, China.
Zhang Y; Chinese Society for Stem Cell Research, Shanghai, China.
Xiang P; Chinese Society for Stem Cell Research, Shanghai, China.
Hu S; Chinese Society for Stem Cell Research, Shanghai, China.
Li Q; Chinese Society for Stem Cell Research, Shanghai, China.
Zhang Y; Chinese Society for Stem Cell Research, Shanghai, China.
Xia Y; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Zhu H; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Stacey G; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhou Q; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
Zhao T; State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Chinese Society for Stem Cell Research, Shanghai, China.
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Źródło :
Cell proliferation [Cell Prolif] 2020 Dec; Vol. 53 (12), pp. e12926. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Stem Cell Transplantation*
Cell Differentiation/*physiology
Pluripotent Stem Cells/*cytology
Stem Cells/*cytology
Cell Lineage/physiology ; Embryonic Stem Cells/cytology ; Humans
Czasopismo naukowe

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