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Tytuł :
Inferring TF activities and activity regulators from gene expression data with constraints from TF perturbation data.
Autorzy :
Ma CZ; Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Computer Science and Engineering, Washington University, St. Louis, MO 63130, USA.
Brent MR; Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Computer Science and Engineering, Washington University, St. Louis, MO 63130, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 Jun 09; Vol. 37 (9), pp. 1234-1245.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
DNA-Binding Proteins ; Gene Expression ; Gene Expression Profiling ; Gene Expression Regulation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Investigating the role of the transcriptional regulator Ure2 on the metabolism of Saccharomyces cerevisiae: a multi-omics approach.
Autorzy :
Liu JJ; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Woodruff W; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL, 61801, USA.
Deewan A; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL, 61801, USA.
Jagtap SS; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL, 61801, USA.
Yun EJ; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Biotechnology, Graduate School, Korea University, Seoul, Republic of Korea.
Walukiewicz HE; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL, 61801, USA.
Jin YS; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Rao CV; DOE Center for Advanced Bioenergy and Bioproducts Innovation, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL, 61801, USA. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2021 Jun; Vol. 105 (12), pp. 5103-5112. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Prions*
Saccharomyces cerevisiae Proteins*/metabolism
Wine*
Fermentation ; Glutathione Peroxidase ; Pyruvate Decarboxylase ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
The N-terminal domain of the A12.2 subunit stimulates RNA polymerase I transcription elongation.
Autorzy :
Scull CE; The Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama.
Lucius AL; the Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama.
Schneider DA; The Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2021 May 18; Vol. 120 (10), pp. 1883-1893. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
RNA Polymerase I*/genetics
RNA Polymerase I*/metabolism
Saccharomyces cerevisiae Proteins*
RNA Polymerase II/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Transcription Factors/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Effect of quorum-sensing molecule 2-phenylethanol and ARO genes on Saccharomyces cerevisiae biofilm.
Autorzy :
Zhang D; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Wang F; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Yu Y; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Ding S; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Chen T; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Sun W; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Liang C; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Yu B; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Ying H; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.; School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou, 450000, China.
Liu D; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China. .; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China. .; School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou, 450000, China. .
Chen Y; National Engineering Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China. .; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2021 May; Vol. 105 (9), pp. 3635-3648. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Phenylethyl Alcohol*
Saccharomyces cerevisiae Proteins*/genetics
Biofilms ; Quorum Sensing ; Saccharomyces cerevisiae/genetics ; Transaminases
Czasopismo naukowe
Tytuł :
Super-resolution microscopy reveals the arrangement of inner membrane protein complexes in mammalian mitochondria.
Autorzy :
Palmer CS; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.
Lou J; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.; School of Physics, The University of Melbourne, Parkville, Victoria 3010, Australia.
Kouskousis B; Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria 3004, Australia.; Monash Micro Imaging, Monash University, Clayton, Victoria 3168, Australia.
Pandzic E; Biomedical Imaging Facility, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW 2052, Australia.
Anderson AJ; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.
Kang Y; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.
Hinde E; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.; School of Physics, The University of Melbourne, Parkville, Victoria 3010, Australia.
Stojanovski D; Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Jul 01; Vol. 134 (13). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Saccharomyces cerevisiae Proteins*/metabolism
Animals ; Membrane Proteins/metabolism ; Membrane Transport Proteins/metabolism ; Microscopy ; Mitochondria/metabolism ; Mitochondrial Membrane Transport Proteins/metabolism ; Protein Transport ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Chromatin accessibility profiling in Neurospora crassa reveals molecular features associated with accessible and inaccessible chromatin.
Autorzy :
Ferraro AR; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA.
Ameri AJ; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA.
Lu Z; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
Kamei M; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA.
Schmitz RJ; Department of Genetics, University of Georgia, Athens, GA, 30602, USA.
Lewis ZA; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Jun 19; Vol. 22 (1), pp. 459. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Neurospora crassa*/genetics
Saccharomyces cerevisiae Proteins*
Chromatin/genetics ; Histones/genetics ; Nucleosomes/genetics ; Repressor Proteins ; Saccharomyces cerevisiae
Czasopismo naukowe
Tytuł :
The GID ubiquitin ligase complex just reached the next level of complexity.
Autorzy :
Fechtner L; Institute of Physiological Chemistry, Martin-Luther University Halle-Wittenberg, Halle, Germany.
Pfirrmann T; Institute of Physiological Chemistry, Martin-Luther University Halle-Wittenberg, Halle, Germany; Health and Medical University, Potsdam, Germany. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Jun 03; Vol. 81 (11), pp. 2270-2272.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Saccharomyces cerevisiae Proteins*
Ubiquitin-Protein Ligases*/genetics
Saccharomyces cerevisiae ; Ubiquitin
Czasopismo naukowe
Tytuł :
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity.
Autorzy :
Andersson S; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Romero A; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Rodrigues JI; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Hua S; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Hao X; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.; Institute of Biomedicine - Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Göteborg, Sweden.
Jacobson T; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Karl V; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Becker N; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Ashouri A; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Rauch S; Water Environment Technology, Department of Architecture and Civil Engineering, Chalmers University of Technology, SE-412 96 Göteborg, Sweden.
Nyström T; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.; Institute of Biomedicine - Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Göteborg, Sweden.
Liu B; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
Tamás MJ; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-405 30 Göteborg, Sweden.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Jun 01; Vol. 134 (11). Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arsenic*
Arsenites*/toxicity
Saccharomyces cerevisiae Proteins*/genetics
Protein Aggregates ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach.
Autorzy :
Navarrete-Perea J; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
Guerra-Moreno A; Brigham and Women's Hospital, Boston, Massachusetts 02115, United States.
Van Vranken J; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
Isasa M; C4 Therapeutics, Cambridge, Massachusetts 02142, United States.
Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02155, United States.
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Źródło :
Journal of proteome research [J Proteome Res] 2021 May 07; Vol. 20 (5), pp. 2751-2761. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Iron-Deficiency*
Saccharomyces cerevisiae Proteins*/genetics
Humans ; Iron ; Proteomics ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
Dielectric Spectroscopy Based Detection of Specific and Nonspecific Cellular Mechanisms.
Autorzy :
Stoneman MR; Department of Physics, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.
Raicu V; Department of Physics, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.; Department of Biological Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.
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Źródło :
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 May 03; Vol. 21 (9). Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Journal Article
MeSH Terms :
Dielectric Spectroscopy*
Mating Factor*
Saccharomyces cerevisiae Proteins*
Cell Membrane ; Receptors, Mating Factor ; Saccharomyces cerevisiae
Czasopismo naukowe
Tytuł :
Analysis of the molecular basis of Saccharomyces cerevisiae mutant with high nucleic acid content by comparative transcriptomics.
Autorzy :
Guo X; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, 300457 Tianjin, China. Electronic address: .
Zhao B; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China.
Zhou X; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China.
Lu D; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China.
Wang Y; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China.
Chen Y; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, 300457 Tianjin, China.
Xiao D; Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin 300547, China; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, 300457 Tianjin, China; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, 300457 Tianjin, China.
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2021 Apr; Vol. 142, pp. 110188. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nucleic Acids*
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Mitogen-Activated Protein Kinases ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Autorzy :
Herzog M; The Wellcome/Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; The Wellcome Sanger Institute, Hinxton CB10 1HH, UK.
Alonso-Perez E; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 9 C, 413 90, Göteborg, Sweden.
Salguero I; The Wellcome/Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.
Warringer J; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 9 C, 413 90, Göteborg, Sweden.
Adams DJ; The Wellcome Sanger Institute, Hinxton CB10 1HH, UK.
Jackson SP; The Wellcome/Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.
Puddu F; The Wellcome/Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 19; Vol. 49 (7), pp. 3919-3931.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms*/enzymology
Colorectal Neoplasms*/genetics
DNA Polymerase II*/genetics
DNA Polymerase II*/metabolism
Mutation Rate*
Poly-ADP-Ribose Binding Proteins*/genetics
Poly-ADP-Ribose Binding Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
DNA Replication ; Humans ; Mutagenesis ; Mutation ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
DNA-driven condensation assembles the meiotic DNA break machinery.
Autorzy :
Claeys Bouuaert C; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA. .; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium. .
Pu S; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA.
Wang J; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Oger C; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium.
Daccache D; Louvain Institute of Biomolecular Science and Technology, Université Catholique de Louvain, Louvain-La-Neuve, Belgium.
Xie W; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Patel DJ; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Keeney S; Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA. .
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Źródło :
Nature [Nature] 2021 Apr; Vol. 592 (7852), pp. 144-149. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Meiosis*
Saccharomyces cerevisiae*/cytology
Saccharomyces cerevisiae*/genetics
DNA, Fungal/*metabolism
Nuclear Proteins/*metabolism
Nucleoproteins/*metabolism
Recombinases/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
DNA, Fungal/chemistry ; Endodeoxyribonucleases/metabolism ; Homologous Recombination ; Nuclear Proteins/chemistry ; Nucleoproteins/chemistry ; Protein Binding ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Recombinases/chemistry ; Saccharomyces cerevisiae Proteins/chemistry
Czasopismo naukowe
Tytuł :
Modified chromosome structure caused by phosphomimetic H2A modulates the DNA damage response by increasing chromatin mobility in yeast.
Autorzy :
García Fernández F; Institut de recherche Saint-Louis (IRSL), Université de Paris, INSERM U944, CNRS UMR7212, Genome and Cell Biology of Diseases Unit, F-75010 Paris, France.
Lemos B; Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA.
Khalil Y; Institut de recherche Saint-Louis (IRSL), Université de Paris, INSERM U944, CNRS UMR7212, Genome and Cell Biology of Diseases Unit, F-75010 Paris, France.
Batrin R; Institut de recherche Saint-Louis (IRSL), Université de Paris, INSERM U944, CNRS UMR7212, Genome and Cell Biology of Diseases Unit, F-75010 Paris, France.
Haber JE; Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA.
Fabre E; Institut de recherche Saint-Louis (IRSL), Université de Paris, INSERM U944, CNRS UMR7212, Genome and Cell Biology of Diseases Unit, F-75010 Paris, France .
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Źródło :
Journal of cell science [J Cell Sci] 2021 Mar 29; Vol. 134 (6). Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Histones*/genetics
Histones*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Chromatin/genetics ; DNA Damage/genetics ; DNA Repair ; Humans ; Phosphorylation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Single-molecule studies illuminate the function of RAD51 paralogs.
Autorzy :
Cejka P; Institute for Research in Biomedicine, Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Bellinzona, 6500, Switzerland; Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule (ETH) Zürich, 8093, Switzerland. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Mar 04; Vol. 81 (5), pp. 898-900.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Rad51 Recombinase*/genetics
Rad51 Recombinase*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
DNA, Single-Stranded/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Single Molecule Imaging
Czasopismo naukowe
Tytuł :
Accumulation of cis- and trans-regulatory variations is associated with phenotypic divergence of a complex trait between yeast species.
Autorzy :
Lupo O; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Krieger G; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Jonas F; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Barkai N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
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Źródło :
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 Feb 09; Vol. 11 (2).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Saccharomyces cerevisiae*
Saccharomyces cerevisiae Proteins*
Cell Cycle Proteins ; Evolution, Molecular ; Forkhead Transcription Factors ; Gene Expression Regulation, Fungal ; Multifactorial Inheritance ; Phenotype ; Phylogeny ; Saccharomyces
SCR Organism :
Saccharomyces paradoxus
Czasopismo naukowe
Tytuł :
In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.
Autorzy :
Lanz MC; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Yugandhar K; Department of Computational Biology, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Gupta S; Department of Computational Biology, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Sanford EJ; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Faça VM; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Vega S; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Joiner AMN; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Fromme JC; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Yu H; Department of Computational Biology, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Smolka MB; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
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Źródło :
EMBO reports [EMBO Rep] 2021 Feb 03; Vol. 22 (2), pp. e51121. Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomycetales*/metabolism
Phosphorylation ; Proteome/genetics ; Proteome/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Enhancing Geranylgeraniol Production by Metabolic Engineering and Utilization of Isoprenol as a Substrate in Saccharomyces cerevisiae .
Autorzy :
Wang J; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Zhu L; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Li Y; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Xu S; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Jiang W; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Biotechnology Research Institute, Shanghai Academy of Agricultural Sciences, Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, People's Republic of China.
Liang C; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Fang Y; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Chu A; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Zhang L; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Ding Z; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Shi G; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Pokaż więcej
Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Apr 21; Vol. 69 (15), pp. 4480-4489. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Diterpenes*
Saccharomyces cerevisiae Proteins*/genetics
Metabolic Engineering ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
How does Sec63 affect the conformation of Sec61 in yeast?
Autorzy :
Bhadra P; Center for Bioinformatics, Saarland University, Saarbrücken, Saarland, Germany.
Yadhanapudi L; Faculty of Natural Sciences and Technology, Saarland University, Saarbrücken, Saarland, Germany.
Römisch K; Faculty of Natural Sciences and Technology, Saarland University, Saarbrücken, Saarland, Germany.
Helms V; Center for Bioinformatics, Saarland University, Saarbrücken, Saarland, Germany.
Pokaż więcej
Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Mar 29; Vol. 17 (3), pp. e1008855. Date of Electronic Publication: 2021 Mar 29 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heat-Shock Proteins*/chemistry
Heat-Shock Proteins*/metabolism
Membrane Transport Proteins*/chemistry
Membrane Transport Proteins*/metabolism
SEC Translocation Channels*/chemistry
SEC Translocation Channels*/metabolism
Saccharomyces cerevisiae Proteins*/chemistry
Saccharomyces cerevisiae Proteins*/metabolism
Cryoelectron Microscopy ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Conformation ; Saccharomyces cerevisiae ; Sepharose/analogs & derivatives ; Sepharose/chemistry ; Sepharose/metabolism
Czasopismo naukowe
Tytuł :
Overproduction of α-Farnesene in Saccharomyces cerevisiae by Farnesene Synthase Screening and Metabolic Engineering.
Autorzy :
Wang J; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Jiang W; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Biotechnology Research Institute, Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai 201106, People's Republic of China.
Liang C; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Zhu L; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Li Y; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Mo Q; Biotechnology Research Institute, Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai 201106, People's Republic of China.
Xu S; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Chu A; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Zhang L; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Ding Z; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Shi G; Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, People's Republic of China.; Jiangsu Provincial Research Center for Bioactive Product Processing Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Pokaż więcej
Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Mar 17; Vol. 69 (10), pp. 3103-3113. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Saccharomyces cerevisiae Proteins*/genetics
Sesquiterpenes*
Metabolic Engineering ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe

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