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Wyszukujesz frazę ""Saccharomyces cerevisiae"" wg kryterium: Temat


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Tytuł:
ARV1 deficiency induces lipid bilayer stress and enhances rDNA stability by activating the unfolded protein response in Saccharomyces cerevisiae.
Autorzy:
Hong S; School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Lee HG; School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Huh WK; School of Biological Sciences, Seoul National University, Seoul, Republic of Korea; Institute of Microbiology, Seoul National University, Seoul, Republic of Korea. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107273. Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Unfolded Protein Response*
DNA, Ribosomal*/metabolism
DNA, Ribosomal*/genetics
Lipid Bilayers/metabolism ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Mitogen-Activated Protein Kinases/metabolism ; Mitogen-Activated Protein Kinases/genetics ; Nicotinamidase/metabolism ; Nicotinamidase/genetics ; Sirtuin 2/metabolism ; Sirtuin 2/genetics ; Silent Information Regulator Proteins, Saccharomyces cerevisiae/metabolism ; Silent Information Regulator Proteins, Saccharomyces cerevisiae/genetics ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Endoplasmic Reticulum/metabolism ; Membrane Proteins/metabolism ; Membrane Proteins/genetics ; Membrane Glycoproteins
Czasopismo naukowe
Tytuł:
Response mechanisms of different Saccharomyces cerevisiae strains to succinic acid.
Autorzy:
Xie CY; College of Architecture and Environment, Sichuan University, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.; Sichuan Environmental Protection Key Laboratory of Organic Wastes Valorization, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.; Engineering Research Center of Alternative Energy Materials & Devices, Ministry of Education, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.
Su RR; College of Architecture and Environment, Sichuan University, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.; Sichuan Environmental Protection Key Laboratory of Organic Wastes Valorization, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.
Wu B; Biogas Institute of Ministry of Agriculture, Renmin Rd. 4-13, Chengdu, 610041, Sichuan, China.
Sun ZY; College of Architecture and Environment, Sichuan University, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.; Sichuan Environmental Protection Key Laboratory of Organic Wastes Valorization, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.; Engineering Research Center of Alternative Energy Materials & Devices, Ministry of Education, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China.
Tang YQ; College of Architecture and Environment, Sichuan University, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China. .; Sichuan Environmental Protection Key Laboratory of Organic Wastes Valorization, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China. .; Engineering Research Center of Alternative Energy Materials & Devices, Ministry of Education, No. 24 South Section 1 First Ring Road, Chengdu, 610065, Sichuan, China. .
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Źródło:
BMC microbiology [BMC Microbiol] 2024 May 08; Vol. 24 (1), pp. 158. Date of Electronic Publication: 2024 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Succinic Acid*/metabolism
Gene Expression Regulation, Fungal*
Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Fermentation
Czasopismo naukowe
Tytuł:
Self-controlled in silico gene knockdown strategies to enhance the sustainable production of heterologous terpenoid by Saccharomyces cerevisiae.
Autorzy:
Zhang N; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China.
Li X; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China.
Zhou Q; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China.
Zhang Y; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China.
Lv B; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China.
Hu B; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China. Electronic address: .
Li C; Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102401, PR China; Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, PR China. Electronic address: .
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Źródło:
Metabolic engineering [Metab Eng] 2024 May; Vol. 83, pp. 172-182. Date of Electronic Publication: 2024 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Metabolic Engineering*
Computer Simulation ; Gene Knockdown Techniques ; Terpenes/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł:
Effect of levan polysaccharide on chronological aging in the yeast Saccharomyces cerevisiae.
Autorzy:
Alugoju P; Natural Products for Neuroprotection and Anti-Ageing Research Unit, Chulalongkorn University, Bangkok 10330, Thailand; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Tencomnao T; Natural Products for Neuroprotection and Anti-Ageing Research Unit, Chulalongkorn University, Bangkok 10330, Thailand; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2024 May; Vol. 266 (Pt 2), pp. 131307. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/drug effects
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/genetics
Fructans*/pharmacology
Oxidative Stress*/drug effects
Antioxidants/pharmacology ; Reactive Oxygen Species/metabolism ; Apoptosis/drug effects ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Membrane Potential, Mitochondrial/drug effects
Czasopismo naukowe
Tytuł:
Ceramide sorting into non-vesicular transport is independent of acyl chain length in budding yeast.
Autorzy:
Schlarmann P; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Hanaoka K; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Ikeda A; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Muñiz M; Department of Cell Biology, Faculty of Biology, University of Seville, Seville, Spain; Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen Del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, Seville, Spain.
Funato K; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jun 30; Vol. 715, pp. 149980. Date of Electronic Publication: 2024 Apr 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ceramides*/metabolism
Golgi Apparatus*/metabolism
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/genetics
Biological Transport ; Saccharomycetales/metabolism ; Saccharomycetales/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Endoplasmic Reticulum/metabolism ; Adenosine Triphosphate/metabolism ; Glycosphingolipids
Czasopismo naukowe
Tytuł:
Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters.
Autorzy:
Karapanagioti F; Department of Biochemistry, University of Groningen, Groningen, Netherlands.
Atlason ÚÁ; Department of Biochemistry, University of Groningen, Groningen, Netherlands.
Slotboom DJ; Department of Biochemistry, University of Groningen, Groningen, Netherlands.
Poolman B; Department of Biochemistry, University of Groningen, Groningen, Netherlands.
Obermaier S; Department of Biochemistry, University of Groningen, Groningen, Netherlands.
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Źródło:
ELife [Elife] 2024 Jun 25; Vol. 13. Date of Electronic Publication: 2024 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Amino Acid Transport Systems*/genetics
Amino Acid Transport Systems*/metabolism
Substrate Specificity ; Evolution, Molecular ; Polyamines/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Genetic Fitness ; Amino Acids/metabolism ; Amino Acids/genetics
Czasopismo naukowe
Tytuł:
Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair.
Autorzy:
Gong W; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Holmberg H; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Lu C; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Huang M; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
Li S; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jun 24; Vol. 52 (11), pp. 6333-6346.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
DNA Repair*
Transcription, Genetic*
Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Transcription Factor TFIIH/metabolism ; Transcription Factor TFIIH/genetics ; Protein Binding ; Protein Domains ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA Damage ; Excision Repair ; Endodeoxyribonucleases
Czasopismo naukowe
Tytuł:
Growth-regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes.
Autorzy:
Abdel-Fattah WR; Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.
Carlsson M; Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, Box 7026, SE-750 07 Uppsala, Sweden.
Hu GZ; Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, Box 7026, SE-750 07 Uppsala, Sweden.
Singh A; Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.
Vergara A; Department of Plant Physiology, Umeå University, SE-901 87 Umeå, Sweden.
Aslam R; Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.
Ronne H; Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, Box 7026, SE-750 07 Uppsala, Sweden.
Björklund S; Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jun 24; Vol. 52 (11), pp. 6220-6233.
Typ publikacji:
Journal Article
MeSH Terms:
Introns*/genetics
Mediator Complex*/metabolism
Mediator Complex*/genetics
Promoter Regions, Genetic*
Ribosomal Proteins*/genetics
Ribosomal Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Binding Sites ; Gene Expression Regulation, Fungal ; Protein Binding ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł:
A high-throughput synthetic biology approach for studying combinatorial chromatin-based transcriptional regulation.
Autorzy:
Alcantar MA; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
English MA; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.
Valeri JA; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Collins JJ; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: .
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Źródło:
Molecular cell [Mol Cell] 2024 Jun 20; Vol. 84 (12), pp. 2382-2396.e9.
Typ publikacji:
Journal Article
MeSH Terms:
Chromatin*/metabolism
Chromatin*/genetics
Synthetic Biology*/methods
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Gene Expression Regulation, Fungal*
Transcription, Genetic*
Gene Regulatory Networks*
High-Throughput Screening Assays/methods ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Supervised Machine Learning ; Chromatin Assembly and Disassembly ; Transcription Factors/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
Metabolic regulation of misfolded protein import into mitochondria.
Autorzy:
Wang Y; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.; Biochemistry, Cellular and Molecular Biology (BCMB) Graduate Program, Johns Hopkins University School of Medicine, Baltimore, United States.
Ruan L; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.
Zhu J; Mechanobiology Institute and Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
Zhang X; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.
Chang AC; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, United States.
Tomaszewski A; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.; Biochemistry, Cellular and Molecular Biology (BCMB) Graduate Program, Johns Hopkins University School of Medicine, Baltimore, United States.
Li R; Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, United States.; Mechanobiology Institute and Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, United States.
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Źródło:
ELife [Elife] 2024 Jun 20; Vol. 12. Date of Electronic Publication: 2024 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/genetics
Mitochondria*/metabolism
Protein Transport*
Protein Folding*
Humans ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Glucose/metabolism
Czasopismo naukowe
Tytuł:
Reversible Kinetics in Multi-nucleotide Addition Catalyzed by S. cerevisiae RNA polymerase II Reveal Slow Pyrophosphate Release.
Autorzy:
Fuller KB; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jacobs RQ; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Schneider DA; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: .
Lucius AL; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2024 Jun 15; Vol. 436 (12), pp. 168606. Date of Electronic Publication: 2024 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Polymerase II*/metabolism
RNA Polymerase II*/genetics
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Diphosphates*/metabolism
Kinetics ; Nucleotides/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/chemistry
Czasopismo naukowe
Tytuł:
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast.
Autorzy:
Görlitz K; Institute of Biology, Department of Microbiology, Universität Kassel, Kassel 34132, Germany.
Bessler L; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-Universität Mainz, Mainz 55128, Germany.
Helm M; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-Universität Mainz, Mainz 55128, Germany.
Schaffrath R; Institute of Biology, Department of Microbiology, Universität Kassel, Kassel 34132, Germany.
Klassen R; Institute of Biology, Department of Microbiology, Universität Kassel, Kassel 34132, Germany.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jun 10; Vol. 52 (10), pp. 5841-5851.
Typ publikacji:
Journal Article
MeSH Terms:
Flucytosine*/pharmacology
Fluorouracil*/pharmacology
RNA, Transfer*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/drug effects
Saccharomyces cerevisiae*/metabolism
Exoribonucleases/metabolism ; Exoribonucleases/genetics ; Methylation ; RNA Stability/drug effects ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; tRNA Methyltransferases/metabolism ; tRNA Methyltransferases/genetics ; Uridine/metabolism
Czasopismo naukowe
Tytuł:
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system.
Autorzy:
Raimi OG; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Ojha H; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Ehses K; Institute of Neuropathology, University Medical Center Göttingen, 37099 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.
Dederer V; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Institute of Pharmaceutical Chemistry, Goethe-Universität, 60438 Frankfurt, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Goethe-Universität, 60438 Frankfurt, Germany.
Lange SM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Rivera CP; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Deegan TD; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.
Chen Y; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Wightman M; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Toth R; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Labib KPM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Mathea S; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Institute of Pharmaceutical Chemistry, Goethe-Universität, 60438 Frankfurt, Germany.; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Goethe-Universität, 60438 Frankfurt, Germany.
Ranson N; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Fernández-Busnadiego R; Institute of Neuropathology, University Medical Center Göttingen, 37099 Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Faculty of Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
Muqit MMK; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.
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Źródło:
Science advances [Sci Adv] 2024 Jun 07; Vol. 10 (23), pp. eadn7191. Date of Electronic Publication: 2024 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Kinases*/metabolism
Protein Kinases*/genetics
Mitochondrial Precursor Protein Import Complex Proteins*/metabolism
Mitochondrial Membrane Transport Proteins*/metabolism
Mitochondrial Membrane Transport Proteins*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/genetics
Humans ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Mitochondria/metabolism ; Protein Binding ; Enzyme Activation ; Models, Molecular ; Protein Subunits/metabolism ; Protein Subunits/genetics
Czasopismo naukowe
Tytuł:
Genome wide nucleosome landscape shapes 3D chromatin organization.
Autorzy:
Fouziya S; Department of Biotechnology, School of Biological Sciences, University of Kashmir, Srinagar, J&K, 190006, India.
Krietenstein N; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark.
Mir US; Centre for Interdisciplinary Research and Innovations, University of Kashmir, Srinagar, J&K, 190006, India.
Mieczkowski J; International Research Agenda 3P Medicine Laboratory, Medical University of Gdansk, Gdansk, Poland.
Khan MA; Department of Biotechnology, School of Biological Sciences, University of Kashmir, Srinagar, J&K, 190006, India.
Baba A; Department of Biotechnology, School of Biological Sciences, University of Kashmir, Srinagar, J&K, 190006, India.
Dar MA; Department of Biotechnology, School of Biological Sciences, University of Kashmir, Srinagar, J&K, 190006, India.
Altaf M; Centre for Interdisciplinary Research and Innovations, University of Kashmir, Srinagar, J&K, 190006, India.
Wani AH; Department of Biotechnology, School of Biological Sciences, University of Kashmir, Srinagar, J&K, 190006, India.
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Źródło:
Science advances [Sci Adv] 2024 Jun 07; Vol. 10 (23), pp. eadn2955. Date of Electronic Publication: 2024 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Nucleosomes*/genetics
Nucleosomes*/metabolism
Chromatin Assembly and Disassembly*
Chromatin*/genetics
Chromatin*/metabolism
Chromatin*/chemistry
Genome, Fungal*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Adenosine Triphosphatases
Czasopismo naukowe
Tytuł:
Expression of Wild-Type and Mutant Human TDP-43 in Yeast Inhibits TOROID (TORC1 Organized in Inhibited Domain) Formation and Autophagy Proportionally to the Levels of TDP-43 Toxicity.
Autorzy:
Park S; Department of Pharmacology, University of Nevada, Reno, NV 89557, USA.
Park SK; Department of Pharmacology, University of Nevada, Reno, NV 89557, USA.
Liebman SW; Department of Pharmacology, University of Nevada, Reno, NV 89557, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jun 06; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*/drug effects
Autophagy*/genetics
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae*/drug effects
Mutation*
Humans ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Protein Aggregates/drug effects ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
The Plasmodiophora brassicae Golgi-localized UPF0016 protein PbGDT1 mediates calcium but not manganese transport in yeast and Nicotiana benthamiana.
Autorzy:
Musharaf Hossain M; Department of Biology, University of Saskatchewan, Saskatoon S7N5E2, Saskatchewan, Canada.
Alinapon CV; Department of Biology, University of Saskatchewan, Saskatoon S7N5E2, Saskatchewan, Canada.
Todd CD; Department of Biology, University of Saskatchewan, Saskatoon S7N5E2, Saskatchewan, Canada.
Wei Y; Department of Biology, University of Saskatchewan, Saskatoon S7N5E2, Saskatchewan, Canada.
Bonham-Smith PC; Department of Biology, University of Saskatchewan, Saskatoon S7N5E2, Saskatchewan, Canada. Electronic address: .
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Źródło:
Fungal genetics and biology : FG & B [Fungal Genet Biol] 2024 Jun; Vol. 172, pp. 103896. Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Nicotiana*/genetics
Manganese*/metabolism
Calcium*/metabolism
Golgi Apparatus*/metabolism
Golgi Apparatus*/genetics
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Homeostasis ; Calcium-Transporting ATPases/genetics ; Calcium-Transporting ATPases/metabolism ; Biological Transport/genetics
Czasopismo naukowe
Tytuł:
Clioquinol rescues yeast cells from Aβ42 toxicity via the inhibition of oxidative damage.
Autorzy:
Zheng Q; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Zhu H; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Lv C; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Zhu Z; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Cui H; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Fan Z; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Sun J; Qinghai Key Laboratory of Qinghai-Tibet Plateau Biological Resources, Northwest Institute of Plateau Biology, The Chinese Academy of Sciences, Xining, China.
Huang Z; College of Biological Science and Medical Engineering, Donghua University, Shanghai, China.
Shi P; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
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Źródło:
Biotechnology journal [Biotechnol J] 2024 Jun; Vol. 19 (6), pp. e2300662.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
Amyloid beta-Peptides*/metabolism
Amyloid beta-Peptides*/toxicity
Saccharomyces cerevisiae*/drug effects
Saccharomyces cerevisiae*/metabolism
Clioquinol*/pharmacology
Reactive Oxygen Species*/metabolism
Glutathione*/metabolism
Antioxidants*/pharmacology
Lipid Peroxidation/drug effects ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Superoxide Dismutase/metabolism ; Superoxide Dismutase/genetics ; Peptide Fragments/metabolism ; Molecular Docking Simulation ; Catalase/metabolism ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism
Czasopismo naukowe
Tytuł:
Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation.
Autorzy:
Ma CR; Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
Liu N; Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.; International Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, 910 Heng Shan Road, Shanghai 200030, China.
Li H; Core Facility of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
Xu H; International Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, 910 Heng Shan Road, Shanghai 200030, China.
Zhou XL; Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 May 22; Vol. 52 (9), pp. 5226-5240.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Transfer*/metabolism
RNA, Transfer*/genetics
RNA, Transfer*/chemistry
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/chemistry
RNA-Binding Proteins*/metabolism
Acetylation ; Mutation ; Nucleic Acid Conformation ; RNA Processing, Post-Transcriptional ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł:
Cymoxanil disrupts RNA synthesis through inhibiting the activity of dihydrofolate reductase.
Autorzy:
Kazmirchuk TDD; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Burnside DJ; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Wang J; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Jagadeesan SK; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Al-Gafari M; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Silva E; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Potter T; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Bradbury-Jost C; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Ramessur NB; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Ellis B; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Takallou S; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Hajikarimlou M; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Moteshareie H; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Said KB; Department of Pathology and Microbiology, University of Hail, 55476, Hail, Saudi Arabia.
Samanfar B; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.; Agriculture and Agri-Food Canada, Ottawa, K1A 0C6, Canada.
Fletcher E; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada.
Golshani A; Department of Biology and the Ottawa Institute of Systems Biology (OISB), Carleton University, Ottawa, K1S 5B6, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2024 May 22; Vol. 14 (1), pp. 11695. Date of Electronic Publication: 2024 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Tetrahydrofolate Dehydrogenase*/metabolism
Tetrahydrofolate Dehydrogenase*/genetics
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/drug effects
Saccharomyces cerevisiae*/metabolism
Molecular Docking Simulation*
Folic Acid Antagonists/pharmacology ; RNA/metabolism ; Humans ; Fungicides, Industrial/pharmacology ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł:
Loss of Conserved rRNA Modifications in the Peptidyl Transferase Center Leads to Diminished Protein Synthesis and Cell Growth in Budding Yeast.
Autorzy:
Leppik M; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
Pomerants L; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
Põldes A; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
Mihkelson P; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
Remme J; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
Tamm T; Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 10; Vol. 25 (10). Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Ribosomal*/genetics
RNA, Ribosomal*/metabolism
Protein Biosynthesis*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Peptidyl Transferases*/metabolism
Peptidyl Transferases*/genetics
Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomycetales/genetics ; Saccharomycetales/metabolism ; Ribosomes/metabolism ; RNA, Small Nucleolar/genetics ; RNA, Small Nucleolar/metabolism ; RNA Processing, Post-Transcriptional ; RNA, Fungal/genetics ; RNA, Fungal/metabolism ; Mutation
Czasopismo naukowe

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