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Wyszukujesz frazę ""Saccharomyces cerevisiae Proteins"" wg kryterium: Temat


Tytuł :
The Thr45Gly substitution in yeast alcohol dehydrogenase substantially decreases catalysis, alters pH dependencies, and disrupts the proton relay system.
Autorzy :
Pal S; Department of Biochemistry, The University of Iowa, Iowa City, IA, 52246, USA.
Plapp BV; Department of Biochemistry, The University of Iowa, Iowa City, IA, 52246, USA. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Nov 01; Vol. 349, pp. 109650. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Journal Article
MeSH Terms :
Alcohol Dehydrogenase/*metabolism
Saccharomyces cerevisiae/*enzymology
Saccharomyces cerevisiae Proteins/*metabolism
Alcohol Dehydrogenase/chemistry ; Alcohol Dehydrogenase/genetics ; Animals ; Binding Sites ; Biocatalysis ; Catalytic Domain ; Horses ; Hydrogen-Ion Concentration ; Kinetics ; Liver/enzymology ; Molecular Dynamics Simulation ; Mutagenesis, Site-Directed ; Protons ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
Crabtree/Warburg-like aerobic xylose fermentation by engineered Saccharomyces cerevisiae.
Autorzy :
Lee SB; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Wisconsin Energy Institute, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI, USA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA; Center for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI, USA.
Tremaine M; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA.
Place M; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA; Center for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI, USA.
Liu L; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA.
Pier A; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA.
Krause DJ; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Wisconsin Energy Institute, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI, USA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA; Center for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI, USA.
Xie D; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA.
Zhang Y; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA.
Landick R; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Gasch AP; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA; Center for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI, USA.
Hittinger CT; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA; Wisconsin Energy Institute, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI, USA; Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI, USA; Center for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: .
Sato TK; DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI, USA. Electronic address: .
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Źródło :
Metabolic engineering [Metab Eng] 2021 Nov; Vol. 68, pp. 119-130. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Xylose*
Biofuels ; Fermentation ; Glucose ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
Engineering of cis-Element in Saccharomyces cerevisiae for Efficient Accumulation of Value-Added Compound Squalene via Downregulation of the Downstream Metabolic Flux.
Autorzy :
Zhou C; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Li M; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Lu S; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Cheng Y; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Guo X; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
He X; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Wang Z; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
He XP; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Oct 27; Vol. 69 (42), pp. 12474-12484. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Down-Regulation ; Ergosterol ; Metabolic Engineering ; Squalene
Czasopismo naukowe
Tytuł :
G 1 cyclin-Cdk promotes cell cycle entry through localized phosphorylation of RNA polymerase II.
Autorzy :
Kõivomägi M; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Swaffer MP; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Turner JJ; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Marinov G; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Skotheim JM; Department of Biology, Stanford University, Stanford, CA 94305, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Oct 15; Vol. 374 (6565), pp. 347-351. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CDC28 Protein Kinase, S cerevisiae/*metabolism
Cell Division/*physiology
Cyclins/*metabolism
RNA Polymerase II/*metabolism
Saccharomyces cerevisiae/*physiology
Saccharomyces cerevisiae Proteins/*metabolism
CDC28 Protein Kinase, S cerevisiae/genetics ; Cell Division/genetics ; Cyclins/genetics ; G1 Phase/genetics ; G1 Phase/physiology ; Gene Expression Regulation, Fungal ; Phosphorylation ; Promoter Regions, Genetic ; Protein Domains ; RNA Polymerase II/chemistry ; Repressor Proteins/metabolism ; Saccharomyces cerevisiae/cytology ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Paths Through the Yeast Regulatory Network in Different Physiological States.
Autorzy :
Lesk AM; Department of Biochemistry and Molecular Biology and Center for Computational Biology and Bioinformatics, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address: .
Konagurthu AS; Department of Data Science and Artificial Intelligence, Monash University, Clayton, VIC 3800, Australia.
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 15; Vol. 433 (21), pp. 167181. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Cell Cycle/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Stress, Physiological/*genetics
Transcription Factors/*genetics
Computational Biology/methods ; DNA Damage ; Gene Expression Profiling ; Gene Expression Regulation, Fungal ; Gene Ontology ; Molecular Sequence Annotation ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/classification ; Saccharomyces cerevisiae Proteins/metabolism ; Signal Transduction ; Spores, Fungal/genetics ; Spores, Fungal/growth & development ; Spores, Fungal/metabolism ; Transcription Factors/classification ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Structural basis of the P4B ATPase lipid flippase activity.
Autorzy :
Bai L; Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Peking University, Beijing, China. .
Jain BK; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
You Q; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.
Duan HD; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.
Takar M; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Graham TR; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. .
Li H; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Oct 13; Vol. 12 (1), pp. 5963. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Triphosphatases/*chemistry
Lysophospholipids/*chemistry
Membrane Transport Proteins/*chemistry
Phosphatidylethanolamines/*chemistry
Phosphatidylserines/*chemistry
Phospholipid Transfer Proteins/*chemistry
Saccharomyces cerevisiae/*enzymology
Saccharomyces cerevisiae Proteins/*chemistry
Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Amino Acid Sequence ; Binding Sites ; Cell Membrane/chemistry ; Cell Membrane/enzymology ; Cloning, Molecular ; Cryoelectron Microscopy ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Isoenzymes/chemistry ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Lysophospholipids/metabolism ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Models, Molecular ; Phosphatidylethanolamines/metabolism ; Phosphatidylserines/metabolism ; Phospholipid Transfer Proteins/genetics ; Phospholipid Transfer Proteins/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Downregulation of the Tem1 GTPase by Amn1 after cytokinesis involves both nuclear import and SCF-mediated degradation.
Autorzy :
Devault A; CRBM (Centre de Recherche en Biologie cellulaire de Montpellier), University of Montpellier, CNRS (Centre National de la Recherche Scientifique), 1919 Route de Mende, 34293 Montpellier, France.
Piatti S; CRBM (Centre de Recherche en Biologie cellulaire de Montpellier), University of Montpellier, CNRS (Centre National de la Recherche Scientifique), 1919 Route de Mende, 34293 Montpellier, France.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Oct 01; Vol. 134 (19). Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Monomeric GTP-Binding Proteins*/genetics
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Active Transport, Cell Nucleus ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cytokinesis ; Down-Regulation/genetics ; Humans ; Mitosis ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Spindle Apparatus/metabolism
Czasopismo naukowe
Tytuł :
Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro.
Autorzy :
Nguyen PQ; Aix-Marseille Université, CNRS, AFMB UMR 7257, Marseille, France.
Conesa C; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Rabut E; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Bragagnolo G; Aix-Marseille Université, CNRS, AFMB UMR 7257, Marseille, France.
Gouzerh C; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Fernández-Tornero C; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.
Lesage P; INSERM U944, CNRS UMR 7212, Genomes and Cell Biology of Disease Unit, Institut de Recherche Saint-Louis, Université de Paris, Hôpital Saint-Louis, Paris, France.
Reguera J; Aix-Marseille Université, CNRS, AFMB UMR 7257, Marseille, France; INSERM, AFMB UMR7257, Marseille, France. Electronic address: .
Acker J; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101093. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Retroelements*
Integrases/*chemistry
Intrinsically Disordered Proteins/*chemistry
Saccharomyces cerevisiae/*enzymology
Saccharomyces cerevisiae Proteins/*chemistry
Integrases/genetics ; Integrases/metabolism ; Intrinsically Disordered Proteins/genetics ; Intrinsically Disordered Proteins/metabolism ; Protein Domains ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Autorzy :
Cereghetti G; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.; PhD Program for Molecular Life Sciences, Life Science Zurich, Zurich, Switzerland.
Wilson-Zbinden C; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.
Kissling VM; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.; PhD Program for Biomolecular Structure and Mechanism, Life Science Zurich, Zurich, Switzerland.
Diether M; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Arm A; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.
Yoo H; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
Piazza I; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Saad S; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
Picotti P; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Drummond DA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
Sauer U; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Dechant R; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland.
Peter M; Institute of Biochemistry, Department of Biology, ETH Zurich, Zurich, Switzerland. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 Oct; Vol. 23 (10), pp. 1085-1094. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Stress, Physiological*
Amyloid/*chemistry
Cell Cycle Proteins/*chemistry
Cytoplasmic Granules/*chemistry
Pyruvate Kinase/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Adenosine Triphosphate/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Fructosediphosphates/metabolism ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism ; Pyruvate Kinase/chemistry ; Pyruvate Kinase/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
Yeast YPK9 deficiency results in shortened replicative lifespan and sensitivity to hydrogen peroxide.
Autorzy :
Zhao W; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Guo F; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Kong L; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Liu J; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Hong X; Institute of Gynecology, Women and Children's Hospital of Guangdong Province, Guangzhou, 511442, China.
Jiang Z; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Song H; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Cui X; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China.; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China.
Ruan J; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China. .; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China. .
Liu X; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Aging Research, Guangdong Medical University, Dongguan, 523808, China. .; Institute of Biochemistry and Molecular Biology, Guangdong Medical University, Dongguan, 523808, China. .
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Źródło :
Biogerontology [Biogerontology] 2021 Oct; Vol. 22 (5), pp. 547-563. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; Hydrogen Peroxide ; Longevity ; Oxidative Stress ; Vacuoles/metabolism
Czasopismo naukowe
Tytuł :
Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca -calmodulin binding.
Autorzy :
Amini M; Experimentelle und Klinische Pharmakologie und Toxikologie/PZMS, Universität des Saarlandes, Homburg, Deutschland; Department of Medical Biochemistry and Molecular Biology/PZMS, Medical School, Saarland University, Homburg, Germany.
Chang Y; Experimentelle und Klinische Pharmakologie und Toxikologie/PZMS, Universität des Saarlandes, Homburg, Deutschland; Department of Medical Biochemistry and Molecular Biology/PZMS, Medical School, Saarland University, Homburg, Germany.
Wissenbach U; Experimentelle und Klinische Pharmakologie und Toxikologie/PZMS, Universität des Saarlandes, Homburg, Deutschland.
Flockerzi V; Experimentelle und Klinische Pharmakologie und Toxikologie/PZMS, Universität des Saarlandes, Homburg, Deutschland.
Schlenstedt G; Department of Medical Biochemistry and Molecular Biology/PZMS, Medical School, Saarland University, Homburg, Germany.
Beck A; Experimentelle und Klinische Pharmakologie und Toxikologie/PZMS, Universität des Saarlandes, Homburg, Deutschland. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101126. Date of Electronic Publication: 2021 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Calcium/*metabolism
Calmodulin/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
TRPC Cation Channels/*metabolism
Vacuoles/*metabolism
Calcium/chemistry ; Calmodulin/antagonists & inhibitors ; Calmodulin/chemistry ; Calmodulin/genetics ; HEK293 Cells ; Humans ; Protein Domains ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Sesterterpenes/pharmacology ; TRPC Cation Channels/chemistry ; TRPC Cation Channels/genetics ; Vacuoles/chemistry ; Vacuoles/genetics
Czasopismo naukowe
Tytuł :
Mapping protein interactions in the active TOM-TIM23 supercomplex.
Autorzy :
Gomkale R; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.
Linden A; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
Neumann P; Department for Molecular Structural Biology, Georg-August-Universität Göttingen, Göttingen, Germany.
Schendzielorz AB; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.
Stoldt S; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany.
Dybkov O; Cellular Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
Kilisch M; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany.
Schulz C; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.
Cruz-Zaragoza LD; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany.
Schwappach B; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany.
Ficner R; Department for Molecular Structural Biology, Georg-August-Universität Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.
Jakobs S; Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Clinic of Neurology, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.
Urlaub H; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen, Germany.
Rehling P; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany. .; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany. .; Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 29; Vol. 12 (1), pp. 5715. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Transport Proteins/*metabolism
Mitochondrial Membrane Transport Proteins/*metabolism
Protein Precursors/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Cell Fractionation ; Cell Nucleus/metabolism ; Cross-Linking Reagents/chemistry ; Mass Spectrometry/methods ; Membrane Transport Proteins/chemistry ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/isolation & purification ; Mitochondria/metabolism ; Mitochondrial Membrane Transport Proteins/chemistry ; Mitochondrial Membrane Transport Proteins/genetics ; Mitochondrial Membrane Transport Proteins/isolation & purification ; Mitochondrial Membranes/metabolism ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Point Mutation ; Protein Binding/genetics ; Protein Interaction Mapping/methods ; Protein Precursors/chemistry ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
Pathway of Hsp70 interactions at the ribosome.
Autorzy :
Lee K; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.; Department of Biochemistry and Biophysics, Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94158, USA.
Ziegelhoffer T; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.
Delewski W; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.
Berger SE; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.; Department of Chemistry, Lafayette College, Easton, PA, 18042, USA.; Biophysics Program, Stanford University, Stanford, CA, 94305, USA.
Sabat G; Biotechnology Center, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.
Craig EA; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 27; Vol. 12 (1), pp. 5666. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
HSP70 Heat-Shock Proteins/*metabolism
Molecular Chaperones/*metabolism
Ribosomes/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Adenosine Triphosphate/metabolism ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/isolation & purification ; Hydrolysis ; Molecular Chaperones/genetics ; Molecular Chaperones/isolation & purification ; Molecular Docking Simulation ; Protein Domains/genetics ; Protein Folding ; Protein Multimerization ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Ribosomal Proteins/metabolism ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/isolation & purification ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Photo-activatable Ub-PCNA probes reveal new structural features of the Saccharomyces cerevisiae Polη/PCNA complex.
Autorzy :
Shen S; Department of Chemistry and Biochemistry, University of Delaware, 214A Drake Hall, Newark, DE 19716, USA.
Davidson GA; Department of Chemistry and Biochemistry, University of Delaware, 214A Drake Hall, Newark, DE 19716, USA.
Yang K; Department of Chemistry and Biochemistry, University of Delaware, 214A Drake Hall, Newark, DE 19716, USA.
Zhuang Z; Department of Chemistry and Biochemistry, University of Delaware, 214A Drake Hall, Newark, DE 19716, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Sep 20; Vol. 49 (16), pp. 9374-9388.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA/*biosynthesis
DNA-Directed DNA Polymerase/*genetics
Proliferating Cell Nuclear Antigen/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Ubiquitin/*genetics
Benzophenones/pharmacology ; DNA/genetics ; DNA Replication/genetics ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/ultrastructure ; DNA-Directed DNA Polymerase/chemistry ; DNA-Directed DNA Polymerase/ultrastructure ; Macromolecular Substances/chemistry ; Macromolecular Substances/ultrastructure ; Mutation/genetics ; Phenylalanine/analogs & derivatives ; Phenylalanine/pharmacology ; Proliferating Cell Nuclear Antigen/chemistry ; Proliferating Cell Nuclear Antigen/ultrastructure ; Protein Binding/drug effects ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/ultrastructure ; Ubiquitin/chemistry ; Ubiquitin/ultrastructure
Czasopismo naukowe
Tytuł :
The small GTPase KlRho5 responds to oxidative stress and affects cytokinesis.
Autorzy :
Musielak M; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Genetik, Barbarastr. 11, D-49076 Osnabrück, Germany.
Sterk CC; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Genetik, Barbarastr. 11, D-49076 Osnabrück, Germany.
Schubert F; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Genetik, Barbarastr. 11, D-49076 Osnabrück, Germany.
Meyer C; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Zoologie, Barbarastr. 11, D-49076 Osnabrück, Germany.
Paululat A; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Zoologie, Barbarastr. 11, D-49076 Osnabrück, Germany.
Heinisch JJ; Universität Osnabrück, Fachbereich Biologie/Chemie, AG Genetik, Barbarastr. 11, D-49076 Osnabrück, Germany.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Sep 15; Vol. 134 (18). Date of Electronic Publication: 2021 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Monomeric GTP-Binding Proteins*
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Actomyosin/metabolism ; Cytokinesis/genetics ; Humans ; Kluyveromyces ; Oxidative Stress
SCR Organism :
Kluyveromyces lactis
Czasopismo naukowe
Tytuł :
The mRNA decapping complex is buffered by nuclear localization.
Autorzy :
Tishinov K; Biozentrum, University of Basel, Spitalstrasse 41, CH-4056 Basel, Switzerland.
Spang A; Biozentrum, University of Basel, Spitalstrasse 41, CH-4056 Basel, Switzerland.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Sep 15; Vol. 134 (18). Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoribonucleases*/genetics
Endoribonucleases*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
DEAD-box RNA Helicases ; RNA Stability/genetics ; Ribonucleoproteins ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
NLIP and HAD-like Domains of Pah1 and Lipin 1 Phosphatidate Phosphatases Are Essential for Their Catalytic Activities.
Autorzy :
Hsu WH; Department of Food Science, Tunghai University, No. 1727, Section 4, Taiwan Boulevard, Xitun District, Taichung 40704, Taiwan.
Huang YH; Department of Food Science, Tunghai University, No. 1727, Section 4, Taiwan Boulevard, Xitun District, Taichung 40704, Taiwan.
Chen PR; Department of Food Science, Tunghai University, No. 1727, Section 4, Taiwan Boulevard, Xitun District, Taichung 40704, Taiwan.
Hsieh LS; Department of Food Science, Tunghai University, No. 1727, Section 4, Taiwan Boulevard, Xitun District, Taichung 40704, Taiwan.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 08; Vol. 26 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Phosphatidate Phosphatase/*chemistry
Phosphatidate Phosphatase/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
Algorithms ; Computational Biology ; Intrinsically Disordered Proteins/chemistry ; Kinetics ; Phosphatidate Phosphatase/genetics ; Protein Domains ; Saccharomyces cerevisiae Proteins/genetics ; Solubility
Czasopismo naukowe
Tytuł :
Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast.
Autorzy :
Denney AS; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Weems AD; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
McMurray MA; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
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Źródło :
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 Sep 06; Vol. 11 (9).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomycetales*/metabolism
HSP90 Heat-Shock Proteins/metabolism ; Humans ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Mutation ; Protein Folding ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
Chemical rescue of mutant proteins in living Saccharomyces cerevisiae cells by naturally occurring small molecules.
Autorzy :
Hassell DS; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Steingesser MG; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Denney AS; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Johnson CR; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
McMurray MA; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
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Źródło :
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 Sep 06; Vol. 11 (9).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Mutant Proteins ; Mutation ; Septins/metabolism
Czasopismo naukowe
Tytuł :
Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5.
Autorzy :
Harris A; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Wagner M; Institute of Biochemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.; Medac GmbH, Theatherstraße 6, Wedel, Germany.
Du D; Department of Biochemistry, University of Cambridge, Cambridge, UK.; School of Life Sciences and Technology, ShanghaiTech University, Pudong, Shanghai, China.
Raschka S; Institute of Biochemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.
Nentwig LM; Institute of Biochemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.
Gohlke H; Institute of Pharmaceutical and Medicinal Pharmacy, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.; John von Neumann Institute for Computing (NIC), Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich GmbH, Jülich, Germany.; Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH, Jülich, Germany.; Institute of Bio- and Geosciences (IBG-4: Bioinformatics), Forschungszentrum Jülich GmbH, Jülich, Germany.
Smits SHJ; Institute of Biochemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.; Center for Structural Studies, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany.
Luisi BF; Department of Biochemistry, University of Cambridge, Cambridge, UK. .
Schmitt L; Institute of Biochemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, Düsseldorf, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 06; Vol. 12 (1), pp. 5254. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP-Binding Cassette Transporters/*chemistry
ATP-Binding Cassette Transporters/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
ATP-Binding Cassette Transporters/genetics ; Adenosine Triphosphate/metabolism ; Catalytic Domain ; Cryoelectron Microscopy ; Detergents/chemistry ; Drug Resistance, Fungal/genetics ; Genetic Pleiotropy ; Hydrolysis ; Mutation ; Protein Conformation ; Protein Domains ; Rhodamines/chemistry ; Rhodamines/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Vanadates/chemistry ; Vanadates/metabolism
Czasopismo naukowe

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