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    Tytuł:
    Optimization and use of near infrared imaging to guide lymph node collection in rhesus macaques (Macaca mulatta).
    Autorzy:
    Smedley JV; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Bochart RM; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Fischer M; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Funderburgh H; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Kelly V; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Crank H; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Armantrout K; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Shiel O; Infectious Disease Resource, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Robertson-LeVay M; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Sternberger N; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Schmaling B; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Roberts S; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Sekiguchi V; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Reusz M; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Schwartz T; Surgical Services Unit, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Meyer KA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
    Webb G; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Gilbride RM; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Dambrauskas N; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
    Andrade D; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
    Wood M; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
    Labriola C; Experimental Pathology Unit, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Axthelm M; Experimental Pathology Unit, Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, USA.
    Derby N; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
    Varco-Merth B; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Fukazawa Y; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Hansen S; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
    Sodora DL; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA.
    Sather DN; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA.
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    Źródło:
    Journal of medical primatology [J Med Primatol] 2022 Oct; Vol. 51 (5), pp. 270-277. Date of Electronic Publication: 2022 Jul 15.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Indocyanine Green*
    Lymph Nodes*/diagnostic imaging
    Animals ; Macaca mulatta ; Obesity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species.
    Autorzy:
    Chang XL; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Reed JS; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Webb GM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Wu HL; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Le J; Quest Clinical Research, San Francisco, California, United States of America.
    Bateman KB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Greene JM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Pessoa C; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Waytashek C; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Weber WC; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Hwang J; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Fischer M; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Moats C; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Shiel O; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Bochart RM; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Crank H; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Siess D; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Giobbi T; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Torgerson J; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Agnor R; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Gao L; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Dhody K; Amarex Clinical Research LLC, Germantown, Maryland, United States of America.
    Lalezari JP; Quest Clinical Research, San Francisco, California, United States of America.
    Bandar IS; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, United States of America.
    Carnate AM; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, United States of America.
    Pang AS; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, United States of America.
    Corley MJ; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, United States of America.
    Kelly S; CytoDyn Inc., Vancouver, Washington, United States of America.
    Pourhassan N; CytoDyn Inc., Vancouver, Washington, United States of America.
    Smedley J; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Bimber BN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Hansen SG; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Ndhlovu LC; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, United States of America.
    Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2022 Mar 31; Vol. 18 (3), pp. e1010396. Date of Electronic Publication: 2022 Mar 31 (Print Publication: 2022).
    Typ publikacji:
    Clinical Study; Journal Article
    MeSH Terms:
    Simian Immunodeficiency Virus*
    Animals ; Antibodies, Monoclonal, Humanized/pharmacology ; HIV Antibodies ; Humans ; Macaca mulatta ; Receptors, CCR5
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques.
    Autorzy:
    Wen J; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles (UCLA), UCLA AIDS Institute, Los Angeles, California, United States of America.
    Cheever T; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Wang L; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles (UCLA), UCLA AIDS Institute, Los Angeles, California, United States of America.
    Wu D; Department of Chemical and Biomolecular Engineering, School of Engineering, UCLA, Los Angeles, California, United States of America.
    Reed J; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Mascola J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda Maryland, United States of America.
    Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda Maryland, United States of America.
    Liu C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda Maryland, United States of America.
    Pegu A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda Maryland, United States of America.
    Sacha JB; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Lu Y; Department of Chemical and Biomolecular Engineering, School of Engineering, UCLA, Los Angeles, California, United States of America.
    Haigwood NL; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Chen ISY; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles (UCLA), UCLA AIDS Institute, Los Angeles, California, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 Jul 20; Vol. 17 (7), pp. e1009738. Date of Electronic Publication: 2021 Jul 20 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Viral/*administration & dosage
    Brain/*virology
    Broadly Neutralizing Antibodies/*administration & dosage
    Simian Acquired Immunodeficiency Syndrome/*virology
    Viral Load/*drug effects
    Animals ; Animals, Newborn ; Blood-Brain Barrier ; Brain/drug effects ; Humans ; Macaca mulatta ; Nanocapsules ; Simian Immunodeficiency Virus
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy.
    Autorzy:
    Verweij MC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Iyer R; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    John N; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Malouli D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Morrow D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Scholz I; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Womack J; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Abdulhaqq S; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Selseth AN; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Oswald K; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Shoemaker R; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Berkemeier B; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Bosche WJ; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Hull M; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Shao J; Population Sciences and Computational Biology Programs, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
    Sacha JB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Edlefsen PT; Population Sciences and Computational Biology Programs, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
    Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, MD 21702, USA.
    Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. .
    Früh K; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. .
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    Źródło:
    Science (New York, N.Y.) [Science] 2021 Apr 30; Vol. 372 (6541). Date of Electronic Publication: 2021 Mar 25.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    CD8-Positive T-Lymphocytes/*immunology
    Cytomegalovirus/*metabolism
    Genetic Vectors/*metabolism
    Histocompatibility Antigens Class I/*metabolism
    Peptide Fragments/*metabolism
    SAIDS Vaccines/*immunology
    Animals ; Cell Line ; Cytomegalovirus/genetics ; Epitopes, T-Lymphocyte/immunology ; Fibroblasts/metabolism ; Genetic Vectors/genetics ; Histocompatibility Antigens Class I/genetics ; Ligands ; Macaca mulatta ; Peptide Fragments/genetics ; Protein Transport ; Simian Immunodeficiency Virus ; HLA-E Antigens
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Viral opportunistic infections in Mauritian cynomolgus macaques undergoing allogeneic stem cell transplantation mirror human transplant infectious disease complications.
    Autorzy:
    Wu HL; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Weber WC; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Shriver-Munsch C; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Swanson T; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Northrup M; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Price H; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Armantrout K; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Robertson-LeVay M; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Reed JS; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Bateman KB; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Mahyari E; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Thomas A; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.; Division of Neuroscience, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Junell SL; Department of Radiation Medicine, Division of Medical Physics, Oregon Health & Science University, Portland, Oregon.
    Hobbs TR; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Martin LD; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    MacAllister R; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Bimber BN; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Slifka MK; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.; Division of Neuroscience, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Legasse AW; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Moats C; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Axthelm MK; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Smedley J; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Lewis AD; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Colgin L; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Meyers G; Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
    Maziarz RT; Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
    Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Stanton JJ; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon.
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    Źródło:
    Xenotransplantation [Xenotransplantation] 2020 Jul; Vol. 27 (4), pp. e12578. Date of Electronic Publication: 2020 Jan 13.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
    MeSH Terms:
    Disease Models, Animal*
    Hematopoietic Stem Cell Transplantation*/adverse effects
    Opportunistic Infections*/virology
    Virus Diseases*
    Allografts ; Animals ; Humans ; Macaca fascicularis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.
    Autorzy:
    Webb GM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Molden J; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, United States of America.
    Busman-Sahay K; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Abdulhaqq S; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Wu HL; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Weber WC; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Bateman KB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Reed JS; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Northrup M; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Maier N; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Tanaka S; ImmunityBio, Los Angeles, California, United States of America.
    Gao L; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Davey B; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, United States of America.
    Carpenter BL; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, United States of America.
    Axthelm MK; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Stanton JJ; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Smedley J; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Greene JM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Safrit JT; NantKWest, Los Angeles, California, United States of America.
    Estes JD; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Skinner PJ; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, United States of America.
    Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2020 Mar 12; Vol. 16 (3), pp. e1008339. Date of Electronic Publication: 2020 Mar 12 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Anti-Retroviral Agents/*administration & dosage
    B-Lymphocytes/*drug effects
    CD8-Positive T-Lymphocytes/*drug effects
    HIV Infections/*drug therapy
    Interleukin-15/*antagonists & inhibitors
    Killer Cells, Natural/*drug effects
    Proteins/*administration & dosage
    Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; Cell Movement/drug effects ; Disease Models, Animal ; HIV Infections/genetics ; HIV Infections/immunology ; HIV Infections/physiopathology ; HIV-1/drug effects ; HIV-1/physiology ; Humans ; Interleukin-15/genetics ; Interleukin-15/immunology ; Killer Cells, Natural/cytology ; Killer Cells, Natural/immunology ; Lymph Nodes/drug effects ; Lymph Nodes/immunology ; Macaca mulatta ; Recombinant Fusion Proteins ; Simian Acquired Immunodeficiency Syndrome/drug therapy ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/physiopathology ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/drug effects ; Simian Immunodeficiency Virus/physiology ; Virus Latency/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.
    Autorzy:
    Steinbach RJ; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Haese NN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Smith JL; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Colgin LMA; Division of Comparative Medicine, Pathology Services Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    MacAllister RP; Division of Comparative Medicine, Clinical Medicine Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Greene JM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Parkins CJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Kempton JB; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Porsov E; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Wang X; Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Renner LM; Department of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    McGill TJ; Department of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Dozier BL; Division of Comparative Medicine, Clinical Medicine Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Kreklywich CN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Andoh TF; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Grafe MR; Department of Pathology, Oregon Health & Science University, Portland, Oregon, United States of America.
    Pecoraro HL; Veterinary Diagnostic Services Department, North Dakota State University, Fargo, North Dakota, United States of America.
    Hodge T; Division of Comparative Medicine, Time Mated Breeding Services Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Friedman RM; Department of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Houser LA; Division of Comparative Medicine, Behavioral Services Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Morgan TK; Department of Pathology, Oregon Health & Science University, Portland, Oregon, United States of America.; Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, United States of America.
    Stenzel P; Department of Pathology, Oregon Health & Science University, Portland, Oregon, United States of America.
    Lindner JR; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Schelonka RL; Division of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America.
    Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Roberts VHJ; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Neuringer M; Department of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
    Brigande JV; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Kroenke CD; Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Frias AE; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.; Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, United States of America.
    Lewis AD; Division of Comparative Medicine, Pathology Services Unit, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Kelleher MA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Hirsch AJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
    Streblow DN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
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    Źródło:
    PloS one [PLoS One] 2020 Jan 14; Vol. 15 (1), pp. e0227676. Date of Electronic Publication: 2020 Jan 14 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Disease Models, Animal*
    Zika Virus/*pathogenicity
    Zika Virus Infection/*veterinary
    Animals ; Cardiomyopathies/virology ; Female ; Fetus/virology ; Macaca mulatta ; Microcephaly/virology ; Pregnancy ; Pregnancy Complications, Infectious/veterinary ; Pregnancy Complications, Infectious/virology ; Pregnancy Trimester, First ; Seizures/virology ; Zika Virus Infection/virology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers.
    Autorzy:
    de Mulder M; Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Ross Hall 604, 2300 Eye St. NW, Washington, DC, 20037, USA. .
    SenGupta D; Gilead Sciences Inc., Foster City, CA, USA.; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
    Deeks SG; HIV/AIDS Program, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
    Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
    Pilcher CD; HIV/AIDS Program, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
    Hecht FM; HIV/AIDS Program, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
    Sacha JB; Division of Pathobiology and Immunology, Oregon Health and Science University, Portland, CA, USA.
    Nixon DF; Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Ross Hall 604, 2300 Eye St. NW, Washington, DC, 20037, USA.; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
    Michaud HA; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Equipe Immunité et Cancer, Institut de Recherche en Cancérlogie de Montpellier, Montpellier, France.
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    Źródło:
    Retrovirology [Retrovirology] 2017 Aug 22; Vol. 14 (1), pp. 41. Date of Electronic Publication: 2017 Aug 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Capsid Proteins/*immunology
    Endogenous Retroviruses/*immunology
    HIV Antibodies/*blood
    HIV Infections/*immunology
    HIV-1/*immunology
    Cells, Cultured ; Epitopes/chemistry ; Epitopes/immunology ; Gene Products, gag/immunology ; HIV Infections/blood ; Humans ; Peptide Fragments/chemistry ; Peptide Fragments/immunology ; Recombinant Proteins/immunology ; Viral Proteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication.
    Autorzy:
    Ericsen AJ; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.; Virology Training Program, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Lauck M; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Mohns MS; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    DiNapoli SR; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States Of America.
    Mutschler JP; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
    Greene JM; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Weinfurter JT; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Lehrer-Brey G; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
    Prall TM; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
    Gieger SM; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Buechler CR; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Crosno KA; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
    Peterson EJ; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
    Reynolds MR; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Wiseman RW; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon National Primate Research Center, and Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States Of America.
    Estes JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, United States Of America.
    Sacha JB; Vaccine & Gene Therapy Institute, Oregon National Primate Research Center, and Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States Of America.
    Friedrich TC; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.
    Brenchley JM; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States Of America.
    O'Connor DH; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States Of America.; Wisconsin National Primate Research Center, Madison, Wisconsin, United States Of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Dec 07; Vol. 12 (12), pp. e1006048. Date of Electronic Publication: 2016 Dec 07 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    DNA, Viral/*blood
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*pathogenicity
    Viremia/*virology
    Animals ; Disease Progression ; Female ; Flow Cytometry ; Immunophenotyping ; Inflammation/immunology ; Inflammation/virology ; Lymphocyte Activation/immunology ; Macaca fascicularis ; Male ; Polymerase Chain Reaction ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Immunodeficiency Virus/immunology ; Virus Replication/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus.
    Autorzy:
    Sturgill ER; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Malouli D; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Hansen SG; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Seo S; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Schneider CL; Department of Life Sciences, Carroll University, Waukesha, Wisconsin, United States of America.
    Womack JL; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Verweij MC; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Ventura AB; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Bhusari A; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Jeffries KM; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Legasse AW; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Axthelm MK; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Hudson AW; Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Picker LJ; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
    Früh K; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Aug 31; Vol. 12 (8), pp. e1005868. Date of Electronic Publication: 2016 Aug 31 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Immune Evasion*
    Lymphocyte Activation*
    Cytomegalovirus/*immunology
    Cytomegalovirus Infections/*immunology
    Killer Cells, Natural/*immunology
    Animals ; Humans ; K562 Cells ; Macaca fascicularis ; Membrane Glycoproteins/immunology ; NK Cell Lectin-Like Receptor Subfamily K/immunology ; Viral Proteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
    Autorzy:
    Abdel-Mohsen M; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
    Chavez L; Blood Systems Research Institute, San Francisco, California, United States of America.
    Tandon R; School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
    Chew GM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Deng X; Blood Systems Research Institute, San Francisco, California, United States of America.
    Danesh A; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
    Keating S; Blood Systems Research Institute, San Francisco, California, United States of America.
    Lanteri M; Blood Systems Research Institute, San Francisco, California, United States of America.
    Samuels ML; RainDance Technologies, Inc., Billerica, Massachusetts, United States of America.
    Hoh R; University of California, San Francisco, California, United States of America.
    Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
    Norris PJ; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
    Niki T; GalPharma Co., Ltd., Takamatsu-shi, Kagawa, Japan.; Department of Immunology and Immunopathology, Kagawa University, Kagawa, Japan.
    Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Hirashima M; GalPharma Co., Ltd., Takamatsu-shi, Kagawa, Japan.; Department of Immunology and Immunopathology, Kagawa University, Kagawa, Japan.
    Deeks SG; University of California, San Francisco, California, United States of America.
    Ndhlovu LC; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Pillai SK; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Jun 02; Vol. 12 (6), pp. e1005677. Date of Electronic Publication: 2016 Jun 02 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*virology
    Galectins/*metabolism
    HIV Infections/*metabolism
    Virus Activation/*physiology
    Virus Latency/*physiology
    Anti-HIV Agents/therapeutic use ; Blotting, Western ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Gene Expression Profiling ; HIV Infections/drug therapy ; HIV Infections/virology ; HIV-1/physiology ; Humans ; Polymerase Chain Reaction ; Transcription, Genetic/physiology ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.
    Autorzy:
    Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Wu HL; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Burwitz BJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Hammond KB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Reed JS; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Ainslie E; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Morrow DW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Selseth AN; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Pathak R; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Malouli D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Legasse AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Nelson JA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Gillespie GM; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
    Walters LC; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
    Brackenridge S; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
    Sharpe HR; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
    López CA; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
    Früh K; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Korber BT; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. The New Mexico Consortium, Los Alamos, NM 87545, USA.
    McMichael AJ; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
    Gnanakaran S; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
    Sacha JB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2016 Feb 12; Vol. 351 (6274), pp. 714-20. Date of Electronic Publication: 2016 Jan 21.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    CD8-Positive T-Lymphocytes/*immunology
    Cytomegalovirus/*immunology
    Epitopes, T-Lymphocyte/*immunology
    Histocompatibility Antigens Class I/*immunology
    Simian Immunodeficiency Virus/*immunology
    Animals ; Antigen Presentation ; Antigenic Variation ; Cytomegalovirus/genetics ; Epitopes, T-Lymphocyte/chemistry ; Genetic Vectors/genetics ; Genetic Vectors/immunology ; Histocompatibility Antigens Class I/chemistry ; Host-Pathogen Interactions/immunology ; Immune Evasion ; Killer Cells, Natural/immunology ; Macaca mulatta ; Protein Structure, Secondary ; Vaccination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Identification and spontaneous immune targeting of an endogenous retrovirus K envelope protein in the Indian rhesus macaque model of human disease.
    Autorzy:
    Wu HL; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, USA. .
    Léon EJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, USA. .; Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR, 97007, USA. .
    Wallace LT; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. .
    Nimiyongskul FA; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. .
    Buechler MB; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. .
    Newman LP; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. .
    Castrovinci PA; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. .
    Paul Johnson R; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA. .
    Gifford RJ; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK. .
    Brad Jones R; Department of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington DC, USA. .
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, USA. sacha@ohsu.edu.; Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR, 97007, USA. sacha@ohsu.edu.
    Pokaż więcej
    Źródło:
    Retrovirology [Retrovirology] 2016 Jan 15; Vol. 13, pp. 6. Date of Electronic Publication: 2016 Jan 15.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Viral/*blood
    Endogenous Retroviruses/*immunology
    Gene Products, env/*immunology
    T-Lymphocytes/*immunology
    Animals ; Endogenous Retroviruses/genetics ; Female ; Gene Products, env/genetics ; Macaca mulatta ; Male ; Molecular Sequence Data ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
    Autorzy:
    Chew GM; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Fujita T; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.; Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.
    Webb GM; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Wu HL; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Reed JS; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Hammond KB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Clayton KL; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
    Ishii N; Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.
    Abdel-Mohsen M; Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
    Liegler T; Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
    Mitchell BI; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Hecht FM; HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
    Ostrowski M; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
    Shikuma CM; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
    Hansen SG; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Maurer M; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America.
    Korman AJ; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America.
    Deeks SG; HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
    Ndhlovu LC; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Jan 07; Vol. 12 (1), pp. e1005349. Date of Electronic Publication: 2016 Jan 07 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*immunology
    CD8-Positive T-Lymphocytes/*immunology
    HIV Infections/*immunology
    Receptors, Immunologic/*immunology
    Animals ; B7-H1 Antigen/immunology ; Cell Separation ; DNA, Viral/analysis ; Disease Progression ; Flow Cytometry ; Humans ; Lymphocyte Activation/immunology ; Macaca mulatta ; RNA, Viral/analysis ; Simian Acquired Immunodeficiency Syndrome/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    T cell inactivation by poxviral B22 family proteins increases viral virulence.
    Autorzy:
    Alzhanova D; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Hammarlund E; Division of Neuroscience, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Reed J; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Meermeier E; Department of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America; Portland Veterans Administration Medical Center, Portland, Oregon, United States of America.
    Rawlings S; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Ray CA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.
    Edwards DM; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Bimber B; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Legasse A; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Planer S; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Sprague J; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Axthelm MK; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Pickup DJ; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.
    Lewinsohn DM; Department of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America; Portland Veterans Administration Medical Center, Portland, Oregon, United States of America.
    Gold MC; Department of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America; Portland Veterans Administration Medical Center, Portland, Oregon, United States of America.
    Wong SW; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Slifka MK; Division of Neuroscience, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Früh K; Vaccine and Gene Therapy Institute, Oregon National Primate Research Center, Portland, Oregon, United States of America; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Portland, Oregon, United States of America.
    Pokaż więcej
    Źródło:
    PLoS pathogens [PLoS Pathog] 2014 May 15; Vol. 10 (5), pp. e1004123. Date of Electronic Publication: 2014 May 15 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Immune Evasion*/genetics
    Poxviridae/*pathogenicity
    Poxviridae Infections/*immunology
    T-Lymphocytes/*immunology
    T-Lymphocytes/*virology
    Viral Proteins/*physiology
    Animals ; CHO Cells ; Cells, Cultured ; Chlorocebus aethiops ; Cricetinae ; Cricetulus ; Female ; HEK293 Cells ; Humans ; Jurkat Cells ; Macaca mulatta ; Mice ; Mice, Inbred BALB C ; Mpox (monkeypox)/immunology ; Poxviridae/genetics ; Poxviridae/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication.
    Autorzy:
    Sheppard NC; Vaccine Research, Worldwide R&D, Pfizer Inc., San Diego, California, United States of America.
    Jones RB; Department of Immunology, University of Toronto, Toronto, ON, Canada.
    Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Nimityongskul FA; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Newman LP; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Buechler MB; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Reed JS; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
    Piaskowski SM; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Weisgrau KL; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Castrovinci PA; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Wilson NA; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Ostrowski MA; Department of Immunology, University of Toronto, Toronto, ON, Canada.
    Park B; Division of Biostatistics, Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, Oregon, United States of America.
    Nixon DF; Division of Experiment Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America.
    Rakasz EG; Wisconsin National Primate Center, University of Wisconsin, Madison, Wisconsin, United States of America.
    Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America; Department of Medical Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2014 Mar 20; Vol. 9 (3), pp. e92012. Date of Electronic Publication: 2014 Mar 20 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Consensus Sequence*
    Vaccination*
    Macaca mulatta/*immunology
    Retroelements/*immunology
    Simian Acquired Immunodeficiency Syndrome/*prevention & control
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*physiology
    Virus Replication/*physiology
    Animals ; Cell Proliferation ; Gene Products, env/immunology ; Gene Products, gag/immunology ; Humans ; Long Interspersed Nucleotide Elements/genetics ; Macaca mulatta/virology ; Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; SAIDS Vaccines/immunology ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Immunodeficiency Virus/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/virology ; Ubiquitin-Protein Ligases
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection.
    Autorzy:
    Michaud HA
    de Mulder M
    SenGupta D
    Deeks SG
    Martin JN
    Pilcher CD
    Hecht FM
    Sacha JB
    Nixon DF; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, USA. .
    Pokaż więcej
    Źródło:
    Retrovirology [Retrovirology] 2014 Jan 28; Vol. 11, pp. 10. Date of Electronic Publication: 2014 Jan 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression*
    Virus Activation*
    Antibodies, Viral/*blood
    Endogenous Retroviruses/*physiology
    HIV Infections/*immunology
    Viral Envelope Proteins/*biosynthesis
    Viral Envelope Proteins/*immunology
    Adult ; Endogenous Retroviruses/immunology ; Female ; Humans ; Male ; Protein Processing, Post-Translational
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Immune clearance of highly pathogenic SIV infection.
    Autorzy:
    Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon 97006, USA.
    Piatak M Jr
    Ventura AB
    Hughes CM
    Gilbride RM
    Ford JC
    Oswald K
    Shoemaker R
    Li Y
    Lewis MS
    Gilliam AN
    Xu G
    Whizin N
    Burwitz BJ
    Planer SL
    Turner JM
    Legasse AW
    Axthelm MK
    Nelson JA
    Früh K
    Sacha JB
    Estes JD
    Keele BF
    Edlefsen PT
    Lifson JD
    Picker LJ
    Pokaż więcej
    Źródło:
    Nature [Nature] 2013 Oct 03; Vol. 502 (7469), pp. 100-4. Date of Electronic Publication: 2013 Sep 11.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    SAIDS Vaccines/*immunology
    Simian Acquired Immunodeficiency Syndrome/*prevention & control
    Simian Immunodeficiency Virus/*immunology
    Animals ; Cytomegalovirus/genetics ; Cytomegalovirus/immunology ; Female ; Macaca mulatta ; Male ; Molecular Sequence Data ; Simian Acquired Immunodeficiency Syndrome/virology ; Time Factors ; Vaccines, Attenuated/immunology ; Viral Load ; Virus Replication/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms.
    Autorzy:
    Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
    Sacha JB
    Hughes CM
    Ford JC
    Burwitz BJ
    Scholz I
    Gilbride RM
    Lewis MS
    Gilliam AN
    Ventura AB
    Malouli D
    Xu G
    Richards R
    Whizin N
    Reed JS
    Hammond KB
    Fischer M
    Turner JM
    Legasse AW
    Axthelm MK
    Edlefsen PT
    Nelson JA
    Lifson JD
    Früh K
    Picker LJ
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2013 May 24; Vol. 340 (6135), pp. 1237874.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    CD8-Positive T-Lymphocytes/*immunology
    Cytomegalovirus/*immunology
    Epitopes, T-Lymphocyte/*immunology
    Genetic Vectors/*immunology
    SAIDS Vaccines/*immunology
    Animals ; Cytokines/immunology ; Cytomegalovirus/genetics ; Female ; Genetic Vectors/genetics ; Histocompatibility Antigens Class II/immunology ; Humans ; Macaca mulatta ; Male ; Membrane Glycoproteins/genetics ; SAIDS Vaccines/administration & dosage ; Viral Envelope Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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