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    Tytuł:
    Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
    Autorzy:
    Dotan I; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Institute of Endocrinology, Beilinson Campus, Rabin Medical Center, Petach Tikva, Israel.
    Yang J; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Ikeda J; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Roth Z; Program in Cell Biology, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Canada.
    Pollock-Tahiri E; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Desai H; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Sivasubramaniyam T; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Rehal S; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Rapps J; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Li YZ; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Le H; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Farber G; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Alchami E; Department of Immunology, University of Toronto, Toronto, Canada.
    Xiao C; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Karim S; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Gronda M; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
    Saikali MF; Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada.
    Tirosh A; Endocrine Cancer Genomics Center, Sheba Medical Center, Tel Hashomer, Israel.
    Wagner KU; Department of Oncology, Wayne State University School of Medicine and Tumor Biology Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
    Genest J; Research Institute of the McGill University Health Centre, Royal Victoria Hospital, Montreal, QC, Canada.
    Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
    Gupta V; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
    Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
    Cummins CL; Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada.
    Lewis GF; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.
    Robbins C; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Immunology, University of Toronto, Toronto, Canada.
    Jongstra-Bilen J; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Immunology, University of Toronto, Toronto, Canada.
    Cybulsky M; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Department of Immunology, University of Toronto, Toronto, Canada.
    Woo M; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. .; Department of Immunology, University of Toronto, Toronto, Canada. .; Division of Endocrinology and Metabolism, Department of Medicine, University Health Network and Sinai Health System, University of Toronto, Toronto, Canada. .
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    Źródło:
    Communications biology [Commun Biol] 2022 Feb 15; Vol. 5 (1), pp. 132. Date of Electronic Publication: 2022 Feb 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Atherosclerosis*/enzymology
    Atherosclerosis*/genetics
    Atherosclerosis*/metabolism
    Cholesterol*/metabolism
    Janus Kinase 2*/deficiency
    Janus Kinase 2*/genetics
    Janus Kinase 2*/metabolism
    Animals ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL
    Czasopismo naukowe
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    Tytuł:
    Activation and gut-homing of peripheral T cells in HIV immunologic non-responders despite long term viral suppression.
    Autorzy:
    Rousseau RK; Department of Immunology, University of Toronto, Toronto, Canada.
    Szadkowski L; Biostatistics Research Unit, University Health Network, Toronto, Canada.
    Kovacs CM; Maple Leaf Medical Clinic, Toronto, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.
    Saikali MF; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
    Nadeem R; Department of Medicine, University of Toronto, Toronto, Canada.
    Malazogu F; Department of Medicine, University of Toronto, Toronto, Canada.
    Huibner S; Department of Medicine, University of Toronto, Toronto, Canada.
    Cummins CL; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
    Kaul R; Department of Immunology, University of Toronto, Toronto, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.; Toronto General Hospital, University Health Network, Toronto, Canada.
    Walmsley SL; Department of Medicine, University of Toronto, Toronto, Canada.; Toronto General Hospital, University Health Network, Toronto, Canada.; Toronto General Hospital Research Institute, Toronto, Canada.
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    Źródło:
    PloS one [PLoS One] 2021 Jul 28; Vol. 16 (7), pp. e0254149. Date of Electronic Publication: 2021 Jul 28 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*immunology
    CD8-Positive T-Lymphocytes/*immunology
    HIV Infections/*immunology
    Adult ; Anti-Retroviral Agents/therapeutic use ; CD4 Lymphocyte Count ; CD4-CD8 Ratio ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/metabolism ; Cross-Sectional Studies ; Female ; HIV Infections/drug therapy ; HLA-DR Antigens/metabolism ; Humans ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/metabolism ; Linear Models ; Lymphocyte Activation ; Male ; Middle Aged ; Phenotype ; Treatment Failure ; Vascular Cell Adhesion Molecule-1/blood
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-2 z 2

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