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    Wyświetlanie 1-19 z 19
    Tytuł:
    Development of the Follow-Up Human 3D Oral Cancer Model in Cancer Treatment.
    Autorzy:
    Igawa K; Neutron Therapy Research Center, Okayama University, Okayama 700-8558, Japan.
    Izumi K; Division of Biomimetics, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
    Sakurai Y; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan.
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    Źródło:
    Biotech (Basel (Switzerland)) [BioTech (Basel)] 2023 May 11; Vol. 12 (2). Date of Electronic Publication: 2023 May 11.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry.
    Autorzy:
    Flieger S; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660, USA.
    Takagaki M; Research Center for Nuclear Physics, Osaka University, 10-1 Mihoga-oka, Ibaraki-City 567-0047, Osaka, Japan.
    Kondo N; Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-1010 Asashiro-Nishi, Kumatori, Sennan-gun 590-0494, Osaka, Japan.
    Lutz MR Jr; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660, USA.
    Gupta Y; Department of Medicine, Infectious Diseases, Mayo Clinic, Jacksonville, FL 32224, USA.
    Ueda H; Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-1010 Asashiro-Nishi, Kumatori, Sennan-gun 590-0494, Osaka, Japan.
    Sakurai Y; Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-1010 Asashiro-Nishi, Kumatori, Sennan-gun 590-0494, Osaka, Japan.
    Moran G; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660, USA.
    Kempaiah P; Department of Medicine, Infectious Diseases, Mayo Clinic, Jacksonville, FL 32224, USA.
    Hosmane N; Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL 60115, USA.
    Suzuki M; Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2-1010 Asashiro-Nishi, Kumatori, Sennan-gun 590-0494, Osaka, Japan.
    Becker DP; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Apr 09; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Boron Neutron Capture Therapy*/methods
    Glioma*
    Humans ; Ligands ; Virus Internalization ; Boron Compounds/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Immunohistochemical Distribution and Neurochemical Characterization of Huntingtin-Associated Protein 1 Immunoreactive Neurons in the Adult Mouse Lingual Ganglia.
    Autorzy:
    Islam MN; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Sakurai Y; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Hiwaki Y; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Tarif AMM; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Afrin M; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.; Department of Anatomy and Histology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
    Meher MM; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.; Department of Basic Laboratory Sciences, Faculty of Medicine and Health Sciences, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.; Department of Microbiology and Public Health, Faculty of Veterinary Medicine and Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.
    Nozaki K; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Masumoto KH; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Yanai A; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.; Department of Basic Laboratory Sciences, Faculty of Medicine and Health Sciences, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
    Jahan MR; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.; Department of Anatomy and Histology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
    Shinoda K; Division of Neuroanatomy, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan.
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    Źródło:
    Brain sciences [Brain Sci] 2023 Feb 03; Vol. 13 (2). Date of Electronic Publication: 2023 Feb 03.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation.
    Autorzy:
    Kondo N; Particle Radiation Oncology Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, 590-0494, Japan. .
    Sakurai Y; Particle Radiation Oncology Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, 590-0494, Japan.
    Takata T; Particle Radiation Oncology Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, 590-0494, Japan.
    Kano K; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.
    Kume K; Proton Medical Research Division, Research and Development Department, The Wakasa Wan Energy Research Center, Fukui, 914-0135, Japan.
    Maeda M; Proton Medical Research Division, Research and Development Department, The Wakasa Wan Energy Research Center, Fukui, 914-0135, Japan.
    Takai N; Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Nagasaki International University, Nagasaki, 859-3298, Japan.
    Suzuki S; Department of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine, Osaka, 545-8585, Japan.
    Eto F; Department of Cellular and Molecular Anatomy and International Mass Imaging Center, Hamamatsu University School of Medicine, Shizuoka, 431-3192, Japan.
    Kikushima K; Department of Cellular and Molecular Anatomy and International Mass Imaging Center, Hamamatsu University School of Medicine, Shizuoka, 431-3192, Japan.
    Wanibuchi H; Department of Molecular Pathology, Osaka Metropolitan University Graduate School of Medicine, Osaka, 545-8585, Japan.
    Miyatake SI; Cancer Center, Osaka Medical and Pharmaceutical University, Osaka, 569-8686, Japan.
    Kajihara T; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, 277-8562, Japan.
    Oda S; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, 277-8562, Japan.
    Setou M; Department of Cellular and Molecular Anatomy and International Mass Imaging Center, Hamamatsu University School of Medicine, Shizuoka, 431-3192, Japan.
    Aoki J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.
    Suzuki M; Particle Radiation Oncology Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, 590-0494, Japan.
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    Źródło:
    Scientific reports [Sci Rep] 2022 May 24; Vol. 12 (1), pp. 8718. Date of Electronic Publication: 2022 May 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Lysophosphatidylcholines*
    Microglia*
    Animals ; Brain ; Chromatography, Liquid ; Inflammation ; Ivermectin ; Lysophospholipids/chemistry ; Memory Disorders ; Mice ; Necrosis ; Receptors, Purinergic P2X4 ; Tandem Mass Spectrometry/methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    HIF-1α affects sensitivity of murine squamous cell carcinoma to boron neutron capture therapy with BPA.
    Autorzy:
    Sanada Y; Particle Radiation Biology, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Takata T; Particle Radiation Medical Physics, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Tanaka H; Particle Radiation Medical Physics, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Sakurai Y; Particle Radiation Medical Physics, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Watanabe T; Particle Radiation Biology, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Suzuki M; Particle Radiation Oncology, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
    Masunaga SI; Particle Radiation Biology, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
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    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2021; Vol. 97 (10), pp. 1441-1449. Date of Electronic Publication: 2021 Jul 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Carcinoma, Squamous Cell*/radiotherapy
    Animals ; Boron Compounds ; Cell Survival ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit ; Large Neutral Amino Acid-Transporter 1 ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Glioma Stem-Like Cells Can Be Targeted in Boron Neutron Capture Therapy with Boronophenylalanine.
    Autorzy:
    Kondo N; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan.
    Hikida M; Department of Life Science, Akita University, Akita 010-8502, Japan.
    Nakada M; Department of Neurosurgery, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan.
    Sakurai Y; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan.
    Hirata E; Division of Tumor Cell Biology and Bioimaging, Cancer Research Institute of Kanazawa University, Kanazawa 920-1192, Japan.; Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan.
    Takeno S; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan.; Department of Radiation Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
    Suzuki M; Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka 590-0494, Japan.
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    Źródło:
    Cancers [Cancers (Basel)] 2020 Oct 19; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 19.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Evaluation of a Novel Boron-Containing α-D-Mannopyranoside for BNCT.
    Autorzy:
    Tsurubuchi T; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
    Shirakawa M; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.; Department of Pharmaceutical Sciences, University of Fukuyama, 1 Sanzo, Gakuen-cho, Fukuyama 729-0292, Hiroshima, Japan.
    Kurosawa W; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Matsumoto K; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Ubagai R; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Umishio H; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Suga Y; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Yamazaki J; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Arakawa A; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Maruyama Y; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Seki T; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Shibui Y; Institute for Innovation, Ajinomoto Co., Inc., 1-1 Suzukichō, Kawasaki-ku, Kawasaki 210-8681, Kanagawa, Japan.
    Yoshida F; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
    Zaboronok A; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
    Suzuki M; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan-gun 590-0494, Osaka, Japan.
    Sakurai Y; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan-gun 590-0494, Osaka, Japan.
    Tanaka H; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan-gun 590-0494, Osaka, Japan.
    Nakai K; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.; Department of Radiation Oncology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
    Ishikawa E; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
    Matsumura A; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
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    Źródło:
    Cells [Cells] 2020 May 21; Vol. 9 (5). Date of Electronic Publication: 2020 May 21.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Boron/*chemistry
    Mannose/*chemistry
    Animals ; Boron/toxicity ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Colonic Neoplasms/pathology ; Disease Models, Animal ; Intracellular Space/metabolism ; Mannose/chemical synthesis ; Mannose/toxicity ; Melanoma, Experimental/pathology ; Mice ; Optical Imaging ; Rats ; Tissue Distribution/drug effects ; Toxicity Tests
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Usefulness of combination with both continuous administration of hypoxic cytotoxin and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential.
    Autorzy:
    Masunaga SI; Particle Radiation Biology, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Sakurai Y; Radiation Medical Physics, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Tanaka H; Radiation Medical Physics, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Takata T; Radiation Medical Physics, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Suzuki M; Particle Radiation Oncology Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Sanada Y; Particle Radiation Biology, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Tano K; Particle Radiation Biology, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Maruhashi A; Radiation Medical Physics, Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan.
    Ono K; Kansai BNCT Medical Center, Osaka Medical College, Osaka, Japan.
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    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2019 Dec; Vol. 95 (12), pp. 1708-1717. Date of Electronic Publication: 2019 Sep 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Hyperthermia, Induced*
    Lung Neoplasms/*secondary
    Melanoma/*pathology
    Tirapazamine/*pharmacology
    Tumor Hypoxia/*drug effects
    Tumor Hypoxia/*radiation effects
    Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Combined Modality Therapy ; Melanoma/drug therapy ; Melanoma/radiotherapy ; Mice ; Tirapazamine/administration & dosage ; Tirapazamine/therapeutic use ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effect of a change in reactor power on response of murine solid tumors in vivo, referring to impact on quiescent tumor cell population.
    Autorzy:
    Masunaga SI; a Particle Radiation Biology, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Sakurai Y; b Radiation Medical Physics, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Tanaka H; b Radiation Medical Physics, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Takata T; b Radiation Medical Physics, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Suzuki M; c Particle Radiation Oncology Center , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Sanada Y; a Particle Radiation Biology, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Tano K; a Particle Radiation Biology, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Maruhashi A; b Radiation Medical Physics, Division of Radiation Life Science , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
    Ono K; c Particle Radiation Oncology Center , Institute for Integrated Radiation and Nuclear Science, Kyoto University , Sennan-gun , Osaka , Japan.
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    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2019 May; Vol. 95 (5), pp. 635-645. Date of Electronic Publication: 2019 Jan 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Relative Biological Effectiveness*
    Animals ; Cell Line, Tumor ; Cell Proliferation/radiation effects ; Cell Survival/radiation effects ; Mice ; Radiation Tolerance
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Early clinical experience utilizing scintillator with optical fiber (SOF) detector in clinical boron neutron capture therapy: its issues and solutions.
    Autorzy:
    Ishikawa M; Department of Biomedical Science and Engineering, Graduate School of Health Science, Hokkaido University, N-12 W-5 Kita-ku, Sapporo, Hokkaido, 060-0812, Japan. .
    Yamamoto T; Faculty of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
    Matsumura A; Faculty of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
    Hiratsuka J; Department of Radiation Oncology, Kawasaki Medical School, Okayama, 701-0192, Japan.
    Miyatake S; Department of Neurosurgery, Osaka Medical College, Osaka, 569-0084, Japan.
    Kato I; Graduate School of Dentistry, Osaka University, Osaka, 565-0871, Japan.
    Sakurai Y; Research Reactor Institute, Kyoto University, Osaka, 590-0494, Japan.
    Kumada H; Faculty of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
    Shrestha SJ; Department of Biomedical Science and Engineering, Graduate School of Health Science, Hokkaido University, N-12 W-5 Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
    Ono K; Research Reactor Institute, Kyoto University, Osaka, 590-0494, Japan.
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    Źródło:
    Radiation oncology (London, England) [Radiat Oncol] 2016 Aug 09; Vol. 11 (1), pp. 105. Date of Electronic Publication: 2016 Aug 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Computer Systems*
    Boron Neutron Capture Therapy/*methods
    Fiber Optic Technology/*methods
    Radiometry/*instrumentation
    Radiometry/*methods
    Calibration ; Humans ; Neoplasms/radiotherapy ; Optical Fibers
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Effect of oxygen pressure during incubation with a (10)B-carrier on (10)B uptake capacity of cultured p53 wild-type and mutated tumor cells: dependency on p53 status of tumor cells and types of (10)B-carriers.
    Autorzy:
    Masunaga S; a Particle Radiation Biology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Tatebe H; b Department of Radiation Oncology , Kinki University School of Medicine , Ohno-Higashi, Osaka-Sayama , Osaka , Japan ;
    Nishimura Y; b Department of Radiation Oncology , Kinki University School of Medicine , Ohno-Higashi, Osaka-Sayama , Osaka , Japan ;
    Tano K; a Particle Radiation Biology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Sanada Y; a Particle Radiation Biology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Moriwaki T; a Particle Radiation Biology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Sakurai Y; c Radiation Medical Physics, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Tanaka H; c Radiation Medical Physics, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Suzuki M; d Particle Radiation Oncology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan.
    Kondo N; d Particle Radiation Oncology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan.
    Maruhashi A; c Radiation Medical Physics, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan ;
    Ono K; d Particle Radiation Oncology, Research Reactor Institute , Kyoto University , Kumatori, Osaka , Japan.
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    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2016; Vol. 92 (4), pp. 187-94. Date of Electronic Publication: 2016 Feb 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron/*pharmacokinetics
    Boron/*therapeutic use
    Carcinoma, Squamous Cell/*metabolism
    Carcinoma, Squamous Cell/*radiotherapy
    Head and Neck Neoplasms/*metabolism
    Head and Neck Neoplasms/*radiotherapy
    Oxygen/*metabolism
    Tumor Suppressor Protein p53/*metabolism
    Boron Neutron Capture Therapy/methods ; Cell Survival/radiation effects ; Drug Carriers/chemistry ; Humans ; Isotopes/pharmacokinetics ; Isotopes/therapeutic use ; Mutation ; Radiopharmaceuticals/pharmacokinetics ; Radiopharmaceuticals/therapeutic use ; Squamous Cell Carcinoma of Head and Neck
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy.
    Autorzy:
    Futamura G; Department of Neurosurgery, Osaka Medical College, Takatsuki, Japan. .
    Kawabata S; Department of Neurosurgery, Osaka Medical College, Takatsuki, Japan. .
    Siba H; Department of Neurosurgery, Osaka Medical College, Takatsuki, Japan. shibatti_.
    Kuroiwa T; Department of Neurosurgery, Osaka Medical College, Takatsuki, Japan. .
    Suzuki M; Particle Radiation Oncology Research Center, Kyoto University Research Reactor Institute, Kumatori, Japan. .
    Kondo N; Particle Radiation Oncology Research Center, Kyoto University Research Reactor Institute, Kumatori, Japan. .
    Ono K; Particle Radiation Oncology Research Center, Kyoto University Research Reactor Institute, Kumatori, Japan. .
    Sakurai Y; Division of Radiation Life Science, Kyoto University Research Reactor Institute, Kumatori, Japan. .
    Tanaka M; Division of Innovative Cancer Therapy, and Department of Surgical Neuro-Oncology The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. .
    Todo T; Division of Innovative Cancer Therapy, and Department of Surgical Neuro-Oncology The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. .
    Miyatake S; Cancer Center, Osaka Medical College, Takatsuki, Japan. .
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    Źródło:
    Radiation oncology (London, England) [Radiat Oncol] 2014 Nov 04; Vol. 9, pp. 237. Date of Electronic Publication: 2014 Nov 04.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Bone Neoplasms/*radiotherapy
    Brain Neoplasms/*radiotherapy
    Neoplasms, Radiation-Induced/*radiotherapy
    Osteosarcoma/*radiotherapy
    Radiotherapy/*adverse effects
    Bone Neoplasms/etiology ; Brain Neoplasms/complications ; Dose-Response Relationship, Radiation ; Female ; Humans ; Middle Aged ; Neoplasms, Radiation-Induced/etiology ; Osteosarcoma/etiology ; Prognosis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Effect of bevacizumab combined with boron neutron capture therapy on local tumor response and lung metastasis.
    Autorzy:
    Masunaga SI; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Sakurai Y; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Tano K; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Tanaka H; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Suzuki M; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Kondo N; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Narabayashi M; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Watanabe T; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Nakagawa Y; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Maruhashi A; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Ono K; Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University, Osaka 590-0494, Japan.
    Pokaż więcej
    Źródło:
    Experimental and therapeutic medicine [Exp Ther Med] 2014 Jul; Vol. 8 (1), pp. 291-301. Date of Electronic Publication: 2014 May 08.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Sonoporation as an enhancing method for boron neutron capture therapy for squamous cell carcinomas.
    Autorzy:
    Yamatomo N
    Iwagami T
    Kato I
    Masunaga S
    Sakurai Y
    Iwai S
    Nakazawa M
    Ono K
    Yura Y; Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, Yamadaoka 1-8, Suita, Osaka, 565-0871, Japan. .
    Pokaż więcej
    Źródło:
    Radiation oncology (London, England) [Radiat Oncol] 2013 Dec 02; Vol. 8, pp. 280. Date of Electronic Publication: 2013 Dec 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy/*methods
    Carcinoma, Squamous Cell/*radiotherapy
    Mouth Neoplasms/*radiotherapy
    Radiotherapy/*methods
    Ultrasonics/*methods
    Animals ; Boron Compounds/chemistry ; Carcinoma, Squamous Cell/pathology ; Cell Line, Tumor ; Cell Membrane/radiation effects ; Female ; Humans ; Isotopes/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Microbubbles ; Mouth Neoplasms/pathology ; Neoplasm Transplantation ; Neutrons ; Phenylalanine/analogs & derivatives ; Phenylalanine/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Usefulness of combined treatment with continuous administration of tirapazamine and mild temperature hyperthermia in γ-ray irradiation in terms of local tumour response and lung metastatic potential.
    Autorzy:
    Masunaga S; Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Osaka, Japan. />Liu Y
    Sakurai Y
    Tanaka H
    Suzuki M
    Kondo N
    Maruhashi A
    Ono K
    Pokaż więcej
    Źródło:
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group [Int J Hyperthermia] 2012; Vol. 28 (7), pp. 636-44. Date of Electronic Publication: 2012 Sep 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hyperthermia, Induced*
    Antineoplastic Agents/*administration & dosage
    Melanoma, Experimental/*therapy
    Triazines/*administration & dosage
    Animals ; Combined Modality Therapy ; Female ; Gamma Rays ; Lung Neoplasms/secondary ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis ; Tirapazamine ; Tumor Burden/drug effects ; Tumor Burden/radiation effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Induction of multinucleation in oral squamous cell carcinoma tissue with mutated p53 surviving boron neutron capture therapy.
    Autorzy:
    Fujita Y; Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, Osaka, Japan.
    Yamamoto N
    Kato I
    Iwai S
    Ono K
    Sakurai Y
    Ohnishi K
    Ohnishi T
    Yura Y
    Pokaż więcej
    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2011 Mar; Vol. 87 (3), pp. 293-301. Date of Electronic Publication: 2010 Dec 10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, p53*
    Mutation*
    Boron Neutron Capture Therapy/*adverse effects
    Carcinoma, Squamous Cell/*genetics
    Carcinoma, Squamous Cell/*radiotherapy
    Mouth Neoplasms/*genetics
    Mouth Neoplasms/*radiotherapy
    Animals ; Boron Compounds/pharmacology ; Cell Line, Tumor ; Cell Proliferation ; Female ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mitosis ; Neoplasm Transplantation ; Phenotype ; Phenylalanine/analogs & derivatives ; Phenylalanine/pharmacology ; Radiation-Sensitizing Agents/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effect of neutron capture therapy on the cell cycle of human squamous cell carcinoma cells.
    Autorzy:
    Kamida A; Department of Oral and Maxillofacial Surgery II, Osaka University Graduate School of Dentistry, Osaka, Japan.
    Fujita Y
    Kato I
    Iwai S
    Ono K
    Suzuki M
    Sakurai Y
    Yura Y
    Pokaż więcej
    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2008 Mar; Vol. 84 (3), pp. 191-9.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Carcinoma, Squamous Cell/*pathology
    Mouth Neoplasms/*pathology
    Boron Compounds/pharmacology ; Carcinoma, Squamous Cell/metabolism ; Cell Cycle/radiation effects ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Survival/radiation effects ; Humans ; Mouth Neoplasms/metabolism ; Phenylalanine/analogs & derivatives ; Phenylalanine/pharmacology ; Tumor Suppressor Protein p53/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The usefulness of mild temperature hyperthermia combined with a newly developed hypoxia-oriented 10B conjugate compound, TX-2100, for boron neutron capture therapy.
    Autorzy:
    Masunaga S; Radiation Oncology Research Laboratory, Research Reactor Institute, Kyoto University, Sennan-gun, Osaka, Japan. />Nagasawa H
    Sakurai Y
    Uto Y
    Hori H
    Nagata K
    Suzuki M
    Maruhashi A
    Kinashi Y
    Ono K
    Pokaż więcej
    Źródło:
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group [Int J Hyperthermia] 2006 Jun; Vol. 22 (4), pp. 287-99.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hyperthermia, Induced*
    Boron Neutron Capture Therapy/*methods
    Hypoxia/*physiopathology
    Animals ; Borohydrides/pharmacology ; Borohydrides/therapeutic use ; Boron Compounds/pharmacology ; Boron Compounds/therapeutic use ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/therapy ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Combined Modality Therapy ; Cyclic N-Oxides/pharmacology ; Cyclic N-Oxides/therapeutic use ; Female ; Fluorescent Antibody Technique ; Mice ; Mice, Inbred C3H ; Micronucleus Tests ; Quinoxalines/pharmacology ; Quinoxalines/therapeutic use ; Quinuclidines/pharmacology ; Quinuclidines/therapeutic use ; Sulfhydryl Compounds/pharmacology ; Sulfhydryl Compounds/therapeutic use ; Time Factors ; Tissue Distribution ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of boron neutron capture therapy on human oral squamous cell carcinoma in a nude mouse model.
    Autorzy:
    Kamida A; Department of Oral and Maxillofacial Surgery II, Osaka University Graduate School of Dentistry, Osaka, Japan.
    Obayashi S
    Kato I
    Ono K
    Suzuki M
    Nagata K
    Sakurai Y
    Yura Y
    Pokaż więcej
    Źródło:
    International journal of radiation biology [Int J Radiat Biol] 2006 Jan; Vol. 82 (1), pp. 21-9.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Boron Neutron Capture Therapy*
    Carcinoma, Squamous Cell/*radiotherapy
    Mouth Neoplasms/*radiotherapy
    Animals ; Apoptosis ; Body Weight/radiation effects ; Boron Compounds/therapeutic use ; Bromodeoxyuridine/metabolism ; Carcinoma, Squamous Cell/blood supply ; Carcinoma, Squamous Cell/pathology ; Female ; Humans ; Immunohistochemistry ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mouth Neoplasms/blood supply ; Mouth Neoplasms/pathology ; Neoplasm Transplantation ; Phenylalanine/analogs & derivatives ; Phenylalanine/therapeutic use ; Transplantation, Heterologous
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-19 z 19

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