Autor: "Sala KA" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Detection of Plasmodium falciparum in laboratory-reared and naturally infected wild mosquitoes using near-infrared spectroscopy.
Autorzy:: Da DF; Institut de Recherche en Sciences de la Santé, Direction Régionale, 399 avenue de la liberté, 01 BP 545, Bobo-Dioulasso 01, Burkina Faso. .
McCabe R; MRC Centre for Global Infectious Disease Analysis, Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UK.
Somé BM; Institut de Recherche en Sciences de la Santé, Direction Régionale, 399 avenue de la liberté, 01 BP 545, Bobo-Dioulasso 01, Burkina Faso.
Esperança PM; MRC Centre for Global Infectious Disease Analysis, Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UK.
Sala KA; Division of Microbiology and Parasitology, Department of Pathology, Cambridge University, Cambridge, CB2 1QP, UK.; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London, UK.
Blight J; Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London, UK.
Blagborough AM; Division of Microbiology and Parasitology, Department of Pathology, Cambridge University, Cambridge, CB2 1QP, UK.
Dowell F; Stored Product Insect and Engineering Research Unit, United States Department of Agriculture/Agricultural Research Services, Center for Grain and Animal Health Research, Manhattan, KS, USA.
Yerbanga SR; Institut de Recherche en Sciences de la Santé, Direction Régionale, 399 avenue de la liberté, 01 BP 545, Bobo-Dioulasso 01, Burkina Faso.
Lefèvre T; MIVEGEC, Montpellier University, IRD, CNRS, Montpellier, France.; Laboratoire Mixte International Sur Les Vecteurs (LAMIVECT), Bobo Dioulasso, Burkina Faso.; Centre de Recherche en Écologie et Évolution de la Santé (CREES), Montpellier, France.
Mouline K; MIVEGEC, Montpellier University, IRD, CNRS, Montpellier, France.; Laboratoire Mixte International Sur Les Vecteurs (LAMIVECT), Bobo Dioulasso, Burkina Faso.
Dabiré RK; Institut de Recherche en Sciences de la Santé, Direction Régionale, 399 avenue de la liberté, 01 BP 545, Bobo-Dioulasso 01, Burkina Faso.; Laboratoire Mixte International Sur Les Vecteurs (LAMIVECT), Bobo Dioulasso, Burkina Faso.
Churcher TS; MRC Centre for Global Infectious Disease Analysis, Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, UK.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 13; Vol. 11 (1), pp. 10289. Date of Electronic Publication: 2021 May 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anopheles/*parasitology
Mosquito Vectors/*parasitology
Plasmodium falciparum/*isolation & purification
Spectroscopy, Near-Infrared/*methods
Animals

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Skocz do pozycji: 2.

Tytuł:: The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.
Autorzy:: Miguel-Blanco C; Global Health, GlaxoSmithKline, Tres Cantos, 28760, Madrid, Spain.
Murithi JM; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Benavente ED; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Angrisano F; Division of Microbiology and Parasitology, Department of Pathology, Cambridge University, Tennis Court Road, Cambridge, CB2 1QP, UK.
Sala KA; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
van Schalkwyk DA; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Vanaerschot M; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Schwach F; Parasites and Microbes Programme, Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.
Fuchter MJ; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, White City Campus, Wood Lane, London, W12 OBZ, UK.
Billker O; Parasites and Microbes Programme, Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Molecular Biology, The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 901 87, Umeå, Sweden.
Sutherland CJ; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Campino SG; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Clark TG; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Blagborough AM; Division of Microbiology and Parasitology, Department of Pathology, Cambridge University, Tennis Court Road, Cambridge, CB2 1QP, UK.; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Fidock DA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, 10032, USA.; Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Herreros E; Global Health, GlaxoSmithKline, Tres Cantos, 28760, Madrid, Spain.; Medicines for Malaria Venture, 20 Route de Pré-Bois, 1215, Geneva 15, Switzerland.
Gamo FJ; Global Health, GlaxoSmithKline, Tres Cantos, 28760, Madrid, Spain.
Baum J; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Delves MJ; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 21; Vol. 11 (1), pp. 1888. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antimalarials/*pharmacology
Drug Resistance/*drug effects
Malaria/*drug therapy
Plasmodium falciparum/*drug effects
Animals ; Antimalarials/chemistry ; Erythrocytes/parasitology ; Host-Parasite Interactions/drug effects ; Humans ; Inhibitory Concentration 50 ; Malaria/parasitology ; Mice ; Molecular Structure ; Plasmodium/drug effects ; Plasmodium/parasitology ; Plasmodium berghei/drug effects ; Plasmodium berghei/parasitology ; Plasmodium falciparum/physiology ; Species Specificity

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Skocz do pozycji: 3.

Tytuł:: Male-Specific Protein Disulphide Isomerase Function is Essential for Plasmodium Transmission and a Vulnerable Target for Intervention.
Autorzy:: Angrisano F; Division of Microbiology and Parasitology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, United Kingdom.
Sala KA; Department of Life Sciences, Imperial College of Science, Technology and Medicine, London, SW7 2AZ, United Kingdom.
Tapanelli S; Department of Life Sciences, Imperial College of Science, Technology and Medicine, London, SW7 2AZ, United Kingdom.
Christophides GK; Department of Life Sciences, Imperial College of Science, Technology and Medicine, London, SW7 2AZ, United Kingdom.
Blagborough AM; Division of Microbiology and Parasitology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, United Kingdom. .; Department of Life Sciences, Imperial College of Science, Technology and Medicine, London, SW7 2AZ, United Kingdom. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Dec 04; Vol. 9 (1), pp. 18300. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Bacitracin*/pharmacology
Bacitracin*/therapeutic use
Malaria*/prevention & control
Malaria*/transmission
Malaria Vaccines*/pharmacology
Malaria Vaccines*/therapeutic use
Plasmodium berghei/*enzymology
Protein Disulfide-Isomerases/*physiology
Animals ; Female ; Male ; Mice ; Plasmodium berghei/drug effects ; Plasmodium berghei/pathogenicity ; Protozoan Proteins/physiology

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Skocz do pozycji: 4.

Tytuł:: Protective efficacy of an IL-12-expressing baculoviral malaria vaccine.
Autorzy:: Iyori M; Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa, Japan.
Blagborough AM; Department of Life Sciences, Imperial College London, London, UK.
Sala KA; Department of Life Sciences, Imperial College London, London, UK.
Nishiura H; Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa, Japan.
Takagi K; Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa, Japan.
Yoshida S; Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kanazawa, Japan.; Pokaż więcej
Źródło:: Parasite immunology [Parasite Immunol] 2017 Dec; Vol. 39 (12).
Typ publikacji:: Journal Article
MeSH Terms:: Antibodies, Protozoan/*immunology
Interleukin-12/*immunology
Malaria Vaccines/*immunology
Plasmodium berghei/*immunology
Plasmodium falciparum/*immunology
Protozoan Proteins/*immunology
Animals ; Baculoviridae/genetics ; Cell Line ; Genetic Vectors/genetics ; Hep G2 Cells ; Humans ; Immunoglobulin G/immunology ; Interferon-gamma/immunology ; Interleukin-12/biosynthesis ; Interleukin-12/genetics ; Mice ; Plasmodium berghei/genetics ; Protozoan Proteins/biosynthesis ; Protozoan Proteins/genetics ; Sporozoites/immunology ; Vaccination

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Skocz do pozycji: 5.

Tytuł:: A novel model fitted to multiple life stages of malaria for assessing efficacy of transmission-blocking interventions.
Autorzy:: Sherrard-Smith E; MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, W2 1PG, UK. .
Churcher TS; MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Upton LM; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Sala KA; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Zakutansky SE; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Slater HC; MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, W2 1PG, UK.
Blagborough AM; Department of Life Sciences, Imperial College London, South Kensington, London, SW7 2AZ, UK.
Betancourt M; Department of Statistics, University of Warwick, Warwick, UK.; Pokaż więcej
Źródło:: Malaria journal [Malar J] 2017 Apr 04; Vol. 16 (1), pp. 137. Date of Electronic Publication: 2017 Apr 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anopheles/*parasitology
Disease Transmission, Infectious/*prevention & control
Drug Evaluation, Preclinical/*methods
Malaria/*parasitology
Malaria/*prevention & control
Plasmodium berghei/*isolation & purification
Animals ; Female ; Humans ; Malaria/transmission ; Mice ; Models, Statistical

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Skocz do pozycji: 6.

Tytuł:: Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts.
Autorzy:: Churcher TS; MRC Centre for Outbreak Analysis and Modelling, Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.
Sinden RE; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.; The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.
Edwards NJ; The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.
Poulton ID; The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.
Rampling TW; The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.
Brock PM; MRC Centre for Outbreak Analysis and Modelling, Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.; Institute of Biodiversity Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Griffin JT; MRC Centre for Outbreak Analysis and Modelling, Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.
Upton LM; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.
Zakutansky SE; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.
Sala KA; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.
Angrisano F; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.
Hill AV; The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom.
Blagborough AM; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2017 Jan 12; Vol. 13 (1), pp. e1006108. Date of Electronic Publication: 2017 Jan 12 (Print Publication: 2017).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anopheles/*parasitology
Insect Vectors/*parasitology
Malaria/*prevention & control
Malaria Vaccines/*administration & dosage
Plasmodium/*immunology
Animals ; Antibodies, Protozoan ; Disease Models, Animal ; Humans ; Malaria/parasitology ; Malaria/transmission ; Mice ; Plasmodium/growth & development ; Population Dynamics ; Protozoan Proteins/immunology ; Salivary Glands/parasitology ; Sporozoites/immunology ; Vaccination

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Skocz do pozycji: 7.

Tytuł:: A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Autorzy:: Baragaña B; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Hallyburton I; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Lee MC; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Norcross NR; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Grimaldi R; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Otto TD; Malaria Programme, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK.
Proto WR; Malaria Programme, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK.
Blagborough AM; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Meister S; University of California, San Diego, School of Medicine, 9500 Gilman Drive 0760, La Jolla, California 92093, USA.
Wirjanata G; Global Health and Tropical Medicine Division, Menzies School of Health Research, Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia.
Ruecker A; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Upton LM; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Abraham TS; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Almeida MJ; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Pradhan A; Department of Global Health, College of Public Health University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, Florida 33612, USA.
Porzelle A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Luksch
Martínez MS; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Luksch T
Bolscher JM; TropIQ Health Sciences, Geert Grooteplein 28, Huispost 268, 6525 GA Nijmegen, The Netherlands.
Woodland A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Norval S; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Zuccotto F; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Thomas J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Simeons F; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Stojanovski L; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Osuna-Cabello M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Brock PM; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Churcher TS; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Sala KA; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Zakutansky SE; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Jiménez-Díaz MB; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Sanz LM; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Riley J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Basak R; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Campbell M; Centre for Drug Candidate Optimisation, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Avery VM; Eskitis Institute, Brisbane Innovation Park, Nathan Campus, Griffith University, Queensland 4111, Australia.
Sauerwein RW; TropIQ Health Sciences, Geert Grooteplein 28, Huispost 268, 6525 GA Nijmegen, The Netherlands.
Dechering KJ; TropIQ Health Sciences, Geert Grooteplein 28, Huispost 268, 6525 GA Nijmegen, The Netherlands.
Noviyanti R; Malaria Pathogenesis Laboratory, Eijkman Institute for Molecular Biology, Jalan Diponegoro 69, 10430 Jakarta, Indonesia.
Campo B; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Frearson JA; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Angulo-Barturen I; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Ferrer-Bazaga S; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Gamo FJ; GlaxoSmithKline, Tres Cantos Medicines Development Campus-Diseases of the Developing World, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Wyatt PG; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Leroy D; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Siegl P; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Delves MJ; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Kyle DE; Department of Global Health, College of Public Health University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, Florida 33612, USA.
Wittlin S; Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland.
Marfurt J; Global Health and Tropical Medicine Division, Menzies School of Health Research, Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia.
Price RN; 1] Global Health and Tropical Medicine Division, Menzies School of Health Research, Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia [2] Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LJ, UK.
Sinden RE; Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Winzeler EA; University of California, San Diego, School of Medicine, 9500 Gilman Drive 0760, La Jolla, California 92093, USA.
Charman SA; Centre for Drug Candidate Optimisation, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Bebrevska L; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Gray DW; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Campbell S; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Fairlamb AH; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Willis PA; Medicines for Malaria Venture, PO Box 1826, 20 route de Pre-Bois, 1215 Geneva 15, Switzerland.
Rayner JC; Malaria Programme, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK.
Fidock DA; 1] Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA [2] Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Read KD; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Gilbert IH; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.; Pokaż więcej
Źródło:: Nature [Nature] 2015 Jun 18; Vol. 522 (7556), pp. 315-20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antimalarials/*pharmacology
Gene Expression Regulation/*drug effects
Malaria/*parasitology
Plasmodium/*drug effects
Plasmodium/*metabolism
Protein Biosynthesis/*drug effects
Quinolines/*pharmacology
Animals ; Antimalarials/administration & dosage ; Antimalarials/adverse effects ; Antimalarials/pharmacokinetics ; Drug Discovery ; Female ; Life Cycle Stages/drug effects ; Liver/drug effects ; Liver/parasitology ; Malaria/drug therapy ; Male ; Models, Molecular ; Peptide Elongation Factor 2/antagonists & inhibitors ; Peptide Elongation Factor 2/metabolism ; Plasmodium/genetics ; Plasmodium/growth & development ; Plasmodium berghei/drug effects ; Plasmodium berghei/physiology ; Plasmodium falciparum/drug effects ; Plasmodium falciparum/metabolism ; Plasmodium vivax/drug effects ; Plasmodium vivax/metabolism ; Quinolines/administration & dosage ; Quinolines/chemistry ; Quinolines/pharmacokinetics

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Skocz do pozycji: 8.

Tytuł:: Structure-function analysis of the Anopheles gambiae LRIM1/APL1C complex and its interaction with complement C3-like protein TEP1.
Autorzy:: Povelones M; Division of Cell and Molecular Biology, Department of Life Sciences, Imperial College, London, United Kingdom.
Upton LM
Sala KA
Christophides GK; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2011 Apr; Vol. 7 (4), pp. e1002023. Date of Electronic Publication: 2011 Apr 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anopheles/*metabolism
Insect Proteins/*metabolism
Multiprotein Complexes/*metabolism
Animals ; Anopheles/genetics ; Anopheles/parasitology ; Hemolymph/metabolism ; Hemolymph/parasitology ; Humans ; Insect Proteins/genetics ; Malaria/genetics ; Malaria/metabolism ; Multiprotein Complexes/genetics ; Plasmodium berghei/genetics ; Plasmodium berghei/metabolism ; Protein Structure, Tertiary ; Structure-Activity Relationship

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