- Tytuł:
- Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs.
- Autorzy:
- Źródło:
- PLoS pathogens [PLoS Pathog] 2014 Jul 03; Vol. 10 (7), pp. e1004245. Date of Electronic Publication: 2014 Jul 03 (Print Publication: 2014).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
- MeSH Terms:
-
Anthelmintics*
Drug Design*
Models, Molecular*
Brugia malayi/*enzymology
Helminth Proteins/*chemistry
Phosphoric Monoester Hydrolases/*chemistry
Animals ; Filariasis/drug therapy ; Filariasis/enzymology ; Protein Structure, Tertiary
Czasopismo naukowe