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Wyszukujesz frazę ""Sampson KJ"" wg kryterium: Autor


Wyświetlanie 1-5 z 5
Tytuł:
Potassium Channels as Therapeutic Targets in Pulmonary Arterial Hypertension.
Autorzy:
Redel-Traub G; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
Sampson KJ; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY 10032, USA.
Kass RS; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY 10032, USA.
Bohnen MS; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.
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Źródło:
Biomolecules [Biomolecules] 2022 Sep 22; Vol. 12 (10). Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Potassium Channels, Tandem Pore Domain*/genetics
Pulmonary Arterial Hypertension*
Channelopathies*/drug therapy
Channelopathies*/genetics
Hypertension, Pulmonary*/drug therapy
Hypertension, Pulmonary*/genetics
Hypertension, Pulmonary*/pathology
Potassium Channels, Voltage-Gated*
Humans ; Endothelin-1 ; Nerve Tissue Proteins/metabolism ; Familial Primary Pulmonary Hypertension/genetics ; Prostaglandins I ; Potassium ; KATP Channels/genetics
Czasopismo naukowe
Tytuł:
Gating mechanisms underlying deactivation slowing by two KCNQ1 atrial fibrillation mutations.
Autorzy:
Peng G; Department of Pharmacology, Columbia University Medical Center, New York, New York 10032, USA.
Barro-Soria R; Department of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA.
Sampson KJ; Department of Pharmacology, Columbia University Medical Center, New York, New York 10032, USA.
Larsson HP; Department of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA.
Kass RS; Department of Pharmacology, Columbia University Medical Center, New York, New York 10032, USA.
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Źródło:
Scientific reports [Sci Rep] 2017 Apr 06; Vol. 7, pp. 45911. Date of Electronic Publication: 2017 Apr 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation, Missense*
Atrial Fibrillation/*genetics
Genetic Predisposition to Disease/*genetics
Ion Channel Gating/*genetics
KCNQ1 Potassium Channel/*genetics
Action Potentials/genetics ; Animals ; Female ; Fluorometry/methods ; Humans ; Kinetics ; Oocytes/metabolism ; Oocytes/physiology ; Patch-Clamp Techniques/methods ; Potassium Channels, Voltage-Gated/genetics ; Xenopus laevis
Czasopismo naukowe
Tytuł:
Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.
Autorzy:
Iyer V; Department of Pharmacology, Columbia University Medical Center, New York, NY.
Roman-Campos D; Department of Pharmacology, Columbia University Medical Center, New York, NY.
Sampson KJ; Department of Pharmacology, Columbia University Medical Center, New York, NY.
Kang G; Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY.
Fishman GI; Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY.
Kass RS; Department of Pharmacology, Columbia University Medical Center, New York, NY.
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Źródło:
Scientific reports [Sci Rep] 2015 Aug 20; Vol. 5, pp. 13287. Date of Electronic Publication: 2015 Aug 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Arrhythmias, Cardiac/*pathology
Long QT Syndrome/*pathology
Purkinje Cells/*pathology
Action Potentials/drug effects ; Animals ; Arrhythmias, Cardiac/physiopathology ; Calcium/metabolism ; Cardiac Conduction System Disease ; Heart Ventricles/pathology ; Intracellular Space/metabolism ; Ion Channel Gating/drug effects ; Long QT Syndrome/physiopathology ; Mexiletine/pharmacology ; Mice, Transgenic ; Mutation/genetics ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; NAV1.5 Voltage-Gated Sodium Channel/genetics ; Patch-Clamp Techniques ; Purkinje Cells/drug effects ; Purkinje Cells/metabolism
SCR Disease Name:
Long QT syndrome type 3
Czasopismo naukowe
Tytuł:
Modeling tissue- and mutation- specific electrophysiological effects in the long QT syndrome: role of the Purkinje fiber.
Autorzy:
Iyer V; Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York, United States of America.
Sampson KJ; Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York, United States of America.
Kass RS; Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Jun 03; Vol. 9 (6), pp. e97720. Date of Electronic Publication: 2014 Jun 03 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Electrophysiological Phenomena*
Models, Cardiovascular*
Heart Ventricles/*physiopathology
Long QT Syndrome/*genetics
Long QT Syndrome/*physiopathology
Mutation/*genetics
Purkinje Fibers/*pathology
Action Potentials ; Arrhythmias, Cardiac/genetics ; Arrhythmias, Cardiac/physiopathology ; Heart Ventricles/metabolism ; Heart Ventricles/pathology ; Humans ; Ion Channel Gating ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; NAV1.5 Voltage-Gated Sodium Channel/genetics ; Organ Specificity ; Patch-Clamp Techniques ; Phenotype ; Purkinje Fibers/physiopathology
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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