Integrative Multi-OMICs Identifies Therapeutic Response Biomarkers and Confirms Fidelity of Clinically Annotated, Serially Passaged Patient-Derived Xenografts Established from Primary and Metastatic Pediatric and AYA Solid Tumors.
Autorzy:
Pandya PH; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Jannu AJ; Department of Biostatistics & Health Data Science Indiana, University School of Medicine, Indianapolis, IN 46202, USA. Bijangi-Vishehsaraei K; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Dobrota E; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Bailey BJ; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Barghi F; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Shannon HE; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Riyahi N; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Damayanti NP; Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Young C; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Malko R; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Justice R; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Albright E; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. SanduskyGE; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Wurtz LD; Department of Orthopedics Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Collier CD; Department of Orthopedics Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Marshall MS; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Gallagher RI; Center for Applied Proteomics and Molecular Medicine, Institute for Biomedical Innovation, George Mason University, Manassas, VA 20110, USA. Wulfkuhle JD; Center for Applied Proteomics and Molecular Medicine, Institute for Biomedical Innovation, George Mason University, Manassas, VA 20110, USA. Petricoin EF; Center for Applied Proteomics and Molecular Medicine, Institute for Biomedical Innovation, George Mason University, Manassas, VA 20110, USA. Coy K; Preclinical Modeling and Therapeutics Core, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Trowbridge M; Preclinical Modeling and Therapeutics Core, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Sinn AL; Preclinical Modeling and Therapeutics Core, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Renbarger JL; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Ferguson MJ; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Huang K; Department of Biostatistics & Health Data Science Indiana, University School of Medicine, Indianapolis, IN 46202, USA. Zhang J; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Saadatzadeh MR; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Pollok KE; Department of Pediatrics, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Pokaż więcej
Źródło:
Cancers [Cancers (Basel)] 2022 Dec 30; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 30.
Aberrant epigenetic and transcriptional events associated with breast cancer risk.
Autorzy:
Marino N; Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA. .; Department of Medicine, Hematology/Oncology Division, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. . German R; Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA. Podicheti R; Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN, 47405, USA. Rusch DB; Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN, 47405, USA. Rockey P; Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA. Huang J; Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN, 47405, USA. SanduskyGE; Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Temm CJ; Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Althouse S; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Nephew KP; Department of Anatomy, Cell Biology, & Physiology, Indiana University, Bloomington, IN, 47405, USA. Nakshatri H; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Liu J; Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN, 47405, USA. Vode A; Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA. Cao S; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. Storniolo AMV; Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center, Indianapolis, IN, 46202, USA.; Department of Medicine, Hematology/Oncology Division, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Pokaż więcej
Źródło:
Clinical epigenetics [Clin Epigenetics] 2022 Feb 09; Vol. 14 (1), pp. 21. Date of Electronic Publication: 2022 Feb 09.
Folate-targeted intraoperative fluorescence, OTL38, in robotic-assisted laparoscopic partial nephrectomy.
Autorzy:
Sulek JE; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA. Steward JE; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA. Bahler CD; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA. Jacobsen MH; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. Sundaram A; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA. Shum CF; Department of Urology, Khoo Teck Puat Hospital, Singapore. SanduskyGE; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. Low PS; Department of Chemistry, Institute for Drug Discovery Purdue University, West Lafayette, IN, USA. Sundaram CP; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA.
Pokaż więcej
Źródło:
Scandinavian journal of urology [Scand J Urol] 2021 Aug; Vol. 55 (4), pp. 331-336. Date of Electronic Publication: 2021 Jun 07.
A phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer.
Autorzy:
Albany C; Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA. Fazal Z; Department of Comparative Biosciences and the Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Singh R; Department of Comparative Biosciences and the Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Bikorimana E; Department of Comparative Biosciences and the Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA. Adra N; Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA. Hanna NH; Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA. Einhorn LH; Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA. Perkins SM; Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA. SanduskyGE; Division of Hematology/Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA. Christensen BC; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Keer H; Astex Pharmaceuticals, Inc, Pleasanton, CA, USA. Fang F; Medical Sciences Program, Indiana University School of Medicine, Bloomington, IN, USA. Nephew KP; Medical Sciences Program, Indiana University School of Medicine, Bloomington, IN, USA. Spinella MJ; Department of Comparative Biosciences and the Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Pokaż więcej
Źródło:
Cancer medicine [Cancer Med] 2021 Jan; Vol. 10 (1), pp. 156-163. Date of Electronic Publication: 2020 Nov 01.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies
