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Wyświetlanie 1-20 z 155
Tytuł:
Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls
Autorzy:
Biria, MarjanAff1, Aff2, IDs4146702338695z_cor1
Banca, PaulaAff1, Aff2
Healy, Máiréad P.Aff1, Aff2
Keser, Engin
Sawiak, Stephen J.Aff2, Aff3
Rodgers, Christopher T.
Rua, CatarinaAff4, Aff5
de Souza, Ana Maria Frota Lisbôa PereiraAff1, Aff2
Marzuki, Aleya A.Aff1, Aff2, Aff6
Sule, Akeem
Ersche, Karen D.Aff7, Aff8, Aff9
Robbins, Trevor W.Aff1, Aff2, IDs4146702338695z_cor12
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Źródło:
Nature Communications. 14(1)
Czasopismo naukowe
Szczegóły
Tytuł:
Early-life stress biases responding to negative feedback and increases amygdala volume and vulnerability to later-life stress
Autorzy:
Dutcher, Ethan G.
Lopez-Cruz, Laura
Pama, E. A. Claudia
Lynall, Mary-EllenAff2, Aff3
Bevers, Iris C. R.
Jones, Jolyon A.
Khan, Shahid
Sawiak, Stephen J.Aff6, Aff7
Milton, Amy L.
Clatworthy, Menna R.
Robbins, Trevor W.
Bullmore, Edward T.
Dalley, Jeffrey W.Aff1, Aff2, IDs41398023023857_cor13
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Źródło:
Translational Psychiatry. 13(1)
Czasopismo naukowe
Szczegóły
Tytuł:
Automated radiosynthesis and preclinical in vivo evaluation of [18F]Fluoroethylpuromycin as a potential radiotracer for imaging protein synthesis with PET.
Autorzy:
Ramakrishnan, Nisha K. (AUTHOR)
Betts, Helen M. (AUTHOR)
Sephton, Selena Milicevic (AUTHOR)
Zhou, Xiaoyun (AUTHOR)
Williamson, David J. (AUTHOR)
Sawiak, Stephen (AUTHOR)
Aigbirhio, Franklin I. (AUTHOR)
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Źródło:
Nuclear Medicine & Biology. Nov2022, Vol. 114, p71-77. 7p.
Czasopismo naukowe
Szczegóły
Tytuł:
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Autorzy:
Sampaziotis F; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK. .; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Muraro D; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Tysoe OC; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.
Sawiak S; Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK.
Beach TE; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.
Godfrey EM; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Upponi SS; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Brevini T; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Wesley BT; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Garcia-Bernardo J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.
Mahbubani K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.
Canu G; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Gieseck R 3rd; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Berntsen NL; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Mulcahy VL; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Academic Department of Medical Genetics, University of Cambridge, Cambridge, Cambridgeshire, UK.
Crick K; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Fear C; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Robinson S; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Swift L; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Gambardella L; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Bargehr J; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Division of Cardiovascular Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Ortmann D; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Brown SE; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Osnato A; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, Cambridgeshire, UK.
Corbett G; Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Gelson WTH; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Mells GF; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.; Academic Department of Medical Genetics, University of Cambridge, Cambridge, Cambridgeshire, UK.
Humphreys P; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.
Davies SE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Amin I; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Gibbs P; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Sinha S; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, Cambridgeshire, UK.
Butler AJ; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
See TC; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Melum E; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Hybrid Technology Hub-Centre of Excellence, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Watson CJE; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.; National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre and the NIHR Blood and Transplant Research Unit (BTRU), Cambridge, Cambridgeshire, UK.; University of Cambridge in collaboration with Newcastle University and in partnership with NHS Blood and Transplant (NHSBT), Cambridge, Cambridgeshire, UK.
Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.
Vallier L; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK. .; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Feb 19; Vol. 371 (6531), pp. 839-846.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell- and Tissue-Based Therapy*
Bile Duct Diseases/*therapy
Bile Ducts/*cytology
Bile Ducts, Intrahepatic/*physiology
Epithelial Cells/*cytology
Organoids/*transplantation
Animals ; Bile ; Bile Ducts/physiology ; Bile Ducts, Intrahepatic/cytology ; Common Bile Duct/cytology ; Epithelial Cells/physiology ; Gallbladder/cytology ; Gene Expression Regulation ; Humans ; Liver/physiology ; Liver Transplantation ; Mesenchymal Stem Cell Transplantation ; Mice ; Organoids/physiology ; RNA-Seq ; Tissue and Organ Procurement ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AS163 - Cholangiocyte organoids are plastic and their identity is controlled by their local microenvironment.
Autorzy:
Sampaziotis, Fotis (AUTHOR)
Muraro, Daniele (AUTHOR)
Tysoe, Olivia C. (AUTHOR)
Beach, Timothy (AUTHOR)
Sawiak, Stephen (AUTHOR)
Godfrey, Edmund (AUTHOR)
Upponi, Sara (AUTHOR)
Wesley, Brandon (AUTHOR)
Garcia-Bernardo, Jose (AUTHOR)
Brevini, Teresa (AUTHOR)
Mahbubani, Krishnaa (AUTHOR)
Cannu, Giovanni (AUTHOR)
Gieseck, Richard (AUTHOR)
Berntsen, Natalie Lie (AUTHOR)
Mulcahy, Victoria (AUTHOR)
Crick, Keziah (AUTHOR)
Fear, Corina (AUTHOR)
Robinson, Sharayne (AUTHOR)
Swift, Lisa (AUTHOR)
Ortmann, Daniel (AUTHOR)
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Źródło:
Journal of Hepatology. 2020 Supplement 1, Vol. 73, pS112-S112. 1p.
Czasopismo naukowe
Szczegóły
Tytuł:
Encephalopathy induced by Alzheimer brain inoculation in a non-human primate.
Autorzy:
Gary C; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Lam S; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Hérard AS; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Koch JE; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; University of Wisconsin Oshkosh, 800 Algoma Boulevard, Oshkosh, WI, 54901, USA.
Petit F; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Gipchtein P; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Sawiak SJ; Wolfson Brain Imaging Centre, University of Cambridge, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Caillierez R; LabEx DISTALZ (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease), Université de Lille, Inserm, CHU-Lille, UMR-S1172, Alzheimer & Tauopathies, Rue Polonovski, 59045, Lille, France.
Eddarkaoui S; LabEx DISTALZ (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease), Université de Lille, Inserm, CHU-Lille, UMR-S1172, Alzheimer & Tauopathies, Rue Polonovski, 59045, Lille, France.
Colin M; LabEx DISTALZ (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease), Université de Lille, Inserm, CHU-Lille, UMR-S1172, Alzheimer & Tauopathies, Rue Polonovski, 59045, Lille, France.
Aujard F; UMR7179 CNRS-MNHN, MECADEV (Adaptive Mechanisms and Evolution), 1 Avenue du Petit Château, 91800, Brunoy, France.
Deslys JP; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, SEPIA, Université Paris-Saclay, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Brouillet E; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Buée L; LabEx DISTALZ (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease), Université de Lille, Inserm, CHU-Lille, UMR-S1172, Alzheimer & Tauopathies, Rue Polonovski, 59045, Lille, France.
Comoy EE; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, SEPIA, Université Paris-Saclay, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.
Pifferi F; UMR7179 CNRS-MNHN, MECADEV (Adaptive Mechanisms and Evolution), 1 Avenue du Petit Château, 91800, Brunoy, France.
Picq JL; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France.; Laboratoire de Psychopathologie et de Neuropsychologie, EA, 2027, Université Paris 8, St-Denis, France.
Dhenain M; Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud, Université Paris-Saclay UMR 9199, Laboratoire des Maladies Neurodégénératives, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France. .; Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut François Jacob, MIRCen, 18 Route du Panorama, F-92265, Fontenay-aux-Roses, France. .
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Corporate Authors:
French Neuropathology Network
Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Sep 04; Vol. 7 (1), pp. 126. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*diagnostic imaging
Alzheimer Disease/*genetics
Brain/*diagnostic imaging
Brain Diseases/*diagnostic imaging
Brain Diseases/*genetics
Alzheimer Disease/pathology ; Animals ; Brain/pathology ; Brain Diseases/pathology ; Cheirogaleidae ; Electroencephalography/methods ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Mice ; Mice, Transgenic ; Primates ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.
Autorzy:
Yang P; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Read C; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Kuc RE; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Nyimanu D; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Williams TL; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Crosby A; Department of Medicine, University of Cambridge, Cambridge, UK.
Buonincontri G; Wolfson Brain Imaging Centre, Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK.
Southwood M; Department of Pathology, Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Sawiak SJ; Wolfson Brain Imaging Centre, Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK.
Glen RC; The Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, UK and Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK.
Morrell NW; Department of Medicine, University of Cambridge, Cambridge, UK.
Davenport AP; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
Maguire JJ; Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 May; Vol. 176 (9), pp. 1206-1221. Date of Electronic Publication: 2019 Apr 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Apelin Receptors/*agonists
Monocrotaline/*pharmacology
Pulmonary Arterial Hypertension/*drug therapy
Animals ; Apelin Receptors/metabolism ; Male ; Pulmonary Arterial Hypertension/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 155

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