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You search for a phrase ""Saxena AK"" according to the criterion: Author

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    Showing 1-18 from 18 results
    Title:
    Verrucous Bowen's disease on the hand successfully treated with prolonged course of topical 5% 5-fluorouracil.
    Authors:
    Lakhani R; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Khullar G; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Sharma S; National Institute of Pathology (ICMR), Safdarjung Hospital Campus, New Delhi, India.
    Saxena AK; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Bhargava A; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
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    Source:
    Dermatologic therapy [Dermatol Ther] 2021 Jan; Vol. 34 (1), pp. e14614. Date of Electronic Publication: 2020 Dec 11.
    Publication Type:
    Letter
    MeSH Terms:
    Bowen's Disease*/drug therapy
    Skin Neoplasms*/drug therapy
    Fluorouracil ; Humans
    Editorial & Opinion
    Full Text  Link opens in a new window Full TextDetails
    Title:
    Generalized leukemia cutis as the initial manifestation of precursor B-cell acute lymphoblastic leukemia in a young male.
    Authors:
    Kanoje PK; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Khullar G; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Yadav AK; Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Saxena AK; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Gupta DK; Department of Clinical Hematology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
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    Source:
    Dermatologic therapy [Dermatol Ther] 2021 Jan; Vol. 34 (1), pp. e14594. Date of Electronic Publication: 2020 Dec 07.
    Publication Type:
    Letter
    MeSH Terms:
    Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/diagnosis
    Precursor Cell Lymphoblastic Leukemia-Lymphoma*
    Skin Neoplasms*/diagnosis
    Humans ; Male ; Precursor Cells, B-Lymphoid
    Editorial & Opinion
    Full Text  Link opens in a new window Full TextDetails
    Title:
    Synthesis, SAR and docking studies of substituted aryl phenylthiazolyl phenylcarboxamide as potential protein tyrosine phosphatase 1B (PTP1B) inhibitors.
    Authors:
    Varshney K; Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India.; Department of Chemistry, Lucknow University, Lucknow, India.
    Gupta AK; Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.
    Rawat A; Biochemistry Division, Central Drug Research Institute, Lucknow, India.
    Srivastava R; Biochemistry Division, Central Drug Research Institute, Lucknow, India.
    Mishra A; Biochemistry Division, Central Drug Research Institute, Lucknow, India.
    Saxena M; Department of Chemistry, Amity University, Lucknow, India.
    Srivastava AK; Biochemistry Division, Central Drug Research Institute, Lucknow, India.
    Jain S; Department of Chemistry, Lucknow University, Lucknow, India.
    Saxena AK; Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India.
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    Source:
    Chemical biology & drug design [Chem Biol Drug Des] 2019 Jul; Vol. 94 (1), pp. 1378-1389. Date of Electronic Publication: 2019 Jun 05.
    Publication Type:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Molecular Docking Simulation*
    Amides/*chemistry
    Enzyme Inhibitors/*chemical synthesis
    Hypoglycemic Agents/*chemical synthesis
    Protein Tyrosine Phosphatase, Non-Receptor Type 1/*antagonists & inhibitors
    Amides/metabolism ; Amides/therapeutic use ; Animals ; Binding Sites ; Blood Glucose/analysis ; Catalytic Domain ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/pathology ; Drug Design ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/therapeutic use ; Glucose Tolerance Test ; Humans ; Hypoglycemic Agents/metabolism ; Hypoglycemic Agents/therapeutic use ; Hypolipidemic Agents/chemistry ; Hypolipidemic Agents/metabolism ; Hypolipidemic Agents/therapeutic use ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Protein Tyrosine Phosphatase, Non-Receptor Type 1/metabolism ; Structure-Activity Relationship
    Academic Journal
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    Title:
    Persistent pruritic rash, fever, and joint pains in a young female.
    Authors:
    Khullar G; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Saxena AK; Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
    Sharma S; Department of Pathology, National Institute of Pathology, New Delhi, India.
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    Source:
    The Australasian journal of dermatology [Australas J Dermatol] 2019 Feb; Vol. 60 (1), pp. e70-e71. Date of Electronic Publication: 2018 Jul 15.
    Publication Type:
    Case Reports; Letter
    MeSH Terms:
    Still's Disease, Adult-Onset/*diagnosis
    Still's Disease, Adult-Onset/*pathology
    Adolescent ; Arthralgia/etiology ; Female ; Fever/etiology ; Humans ; Purpura/etiology ; Still's Disease, Adult-Onset/complications
    Report
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    Title:
    Synthesis of primaquine glyco-conjugates as potential tissue schizontocidal antimalarial agents.
    Authors:
    Azad CS; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Saxena M; Department of Chemistry, Amity University (Lucknow Campus), Lucknow, UP, India.
    Siddiqui AJ; Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Bhardwaj J; Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Puri SK; Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Dutta GP; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Anand N; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, India.
    Saxena AK; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, India.
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    Source:
    Chemical biology & drug design [Chem Biol Drug Des] 2017 Aug; Vol. 90 (2), pp. 254-261. Date of Electronic Publication: 2017 Feb 22.
    Publication Type:
    Journal Article
    MeSH Terms:
    Antimalarials/*chemistry
    Antimalarials/*therapeutic use
    Malaria/*drug therapy
    Plasmodium/*drug effects
    Primaquine/*analogs & derivatives
    Primaquine/*therapeutic use
    Animals ; Antimalarials/chemical synthesis ; Antimalarials/pharmacology ; Female ; Glycoconjugates/chemical synthesis ; Glycoconjugates/chemistry ; Glycoconjugates/pharmacology ; Glycoconjugates/therapeutic use ; Macaca mulatta ; Malaria, Vivax/drug therapy ; Male ; Mice ; Plasmodium cynomolgi/drug effects ; Plasmodium vivax/drug effects ; Primaquine/chemical synthesis ; Primaquine/pharmacology
    Academic Journal
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    Title:
    Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer.
    Authors:
    Singh A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Fatima K; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Srivastava A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Khwaja S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Priya D; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
    Singh A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Mahajan G; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
    Alam S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Saxena AK; Amity University, Lucknow, Uttar Pradesh, India.
    Mondhe DM; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
    Luqman S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Chanda D; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Khan F; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
    Negi AS; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India. .
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    Source:
    Chemical biology & drug design [Chem Biol Drug Des] 2016 Nov; Vol. 88 (5), pp. 625-634. Date of Electronic Publication: 2016 Aug 06.
    Publication Type:
    Editorial; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents/*chemistry
    Gallic Acid/*chemistry
    Indans/*chemistry
    Tubulin Modulators/*chemistry
    Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/toxicity ; Apoptosis/drug effects ; Benzylidene Compounds/chemistry ; Binding Sites ; Biomarkers, Tumor/blood ; Carcinoma, Ehrlich Tumor/drug therapy ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; G2 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Indans/chemical synthesis ; Indans/toxicity ; M Phase Cell Cycle Checkpoints/drug effects ; Mice ; Molecular Docking Simulation ; Protein Structure, Tertiary ; Tubulin/chemistry ; Tubulin/metabolism ; Tubulin Modulators/therapeutic use ; Tubulin Modulators/toxicity
    Report
    Full Text  Link opens in a new window Full TextDetails
    Title:
    Novel Glycoconjugate of 8-Fluoro Norfloxacin Derivatives as Gentamicin-resistant Staphylococcus aureus Inhibitors: Synthesis and Molecular Modelling Studies.
    Authors:
    Azad CS; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
    Bhunia SS; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.; Academy of Scientific and Innovative Research, New Delhi, India.
    Krishna A; Fermentation Technology Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
    Shukla PK; Fermentation Technology Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
    Saxena AK; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.; Academy of Scientific and Innovative Research, New Delhi, India.
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    Source:
    Chemical biology & drug design [Chem Biol Drug Des] 2015 Oct; Vol. 86 (4), pp. 440-6. Date of Electronic Publication: 2015 Jan 20.
    Publication Type:
    Journal Article
    MeSH Terms:
    Drug Resistance, Bacterial*
    Gentamicins*
    Glycoconjugates*/chemical synthesis
    Glycoconjugates*/chemistry
    Glycoconjugates*/pharmacology
    Models, Molecular*
    Norfloxacin*/analogs & derivatives
    Norfloxacin*/chemical synthesis
    Norfloxacin*/chemistry
    Norfloxacin*/pharmacology
    Staphylococcus aureus/*growth & development
    Staphylococcal Infections/drug therapy
    Academic Journal
    Full Text  Link opens in a new window Full TextDetails
    Title:
    CoMFA, CoMSIA, and docking studies on thiolactone-class of potent anti-malarials: identification of essential structural features modulating anti-malarial activity.
    Authors:
    Roy KK; Division of Medicinal and Process Chemistry, Central Drug Research Institute CSIR, Lucknow-226001, India.
    Bhunia SS
    Saxena AK
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    Source:
    Chemical biology & drug design [Chem Biol Drug Des] 2011 Sep; Vol. 78 (3), pp. 483-93. Date of Electronic Publication: 2011 Jul 13.
    Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Drug Design*
    Antimalarials/*chemistry
    Antimalarials/*pharmacology
    Plasmodium falciparum/*drug effects
    Humans ; Malaria, Falciparum/drug therapy ; Models, Molecular ; Quantitative Structure-Activity Relationship ; Thiophenes/chemistry ; Thiophenes/pharmacology
    Academic Journal
    Full Text  Link opens in a new windowDetails
    Title:
    Preparation, crystallization and preliminary X-ray analysis of a complex between the Plasmodium vivax sexual stage 25 kDa protein Pvs25 and a malaria transmission-blocking antibody Fab fragment.
    Authors:
    Saxena AK; Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Twinbrook II, 12441 Parklawn Drive, Rockville, Maryland 20852, USA.
    Singh K
    Long CA
    Garboczi DN
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    Source:
    Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2004 Nov; Vol. 60 (Pt 11), pp. 2054-7. Date of Electronic Publication: 2004 Oct 20.
    Publication Type:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Antibodies, Protozoan/*immunology
    Immunoglobulin Fab Fragments/*immunology
    Malaria, Vivax/*immunology
    Plasmodium vivax/*chemistry
    Plasmodium vivax/*immunology
    Protozoan Proteins/*chemistry
    Protozoan Proteins/*immunology
    Animals ; Antibodies, Protozoan/chemistry ; Antibodies, Protozoan/isolation & purification ; Antigen-Antibody Complex/chemistry ; Antigen-Antibody Complex/immunology ; Chromatography, Gel ; Crystallization ; Crystallography, X-Ray ; Immunoglobulin Fab Fragments/chemistry ; Immunoglobulin Fab Fragments/isolation & purification ; Malaria, Vivax/parasitology ; Mice ; Protozoan Proteins/isolation & purification
    Academic Journal
    Full Text  Link opens in a new windowDetails
    Title:
    Crystallization and preliminary X-ray analysis of the Plasmodium vivax sexual stage 25 kDa protein Pvs25, a transmission-blocking vaccine candidate for malaria.
    Authors:
    Saxena AK; Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Twinbrook II, 12441 Parklawn Drive, Rockville, Maryland 20852, USA.
    Saul A
    Garboczi DN
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    Source:
    Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2004 Apr; Vol. 60 (Pt 4), pp. 706-8. Date of Electronic Publication: 2004 Mar 23.
    Publication Type:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Crystallization*
    Plasmodium vivax/*chemistry
    Protozoan Proteins/*chemistry
    Animals ; Antigens, Protozoan/chemistry ; Antigens, Surface/chemistry ; Cloning, Molecular ; Crystallography, X-Ray ; Malaria Vaccines/chemistry ; Methylation
    Academic Journal
    Full Text  Link opens in a new windowDetails
      Showing 1-18 from 18 results

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