Autor: "Saxena AK" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer.
Autorzy:: Singh A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Fatima K; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Srivastava A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Khwaja S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Priya D; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
Singh A; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Mahajan G; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
Alam S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Saxena AK; Amity University, Lucknow, Uttar Pradesh, India.
Mondhe DM; CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, Jammu and Kashmir, India.
Luqman S; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Chanda D; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Khan F; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India.
Negi AS; CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, Uttar Pradesh, India. .; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2016 Nov; Vol. 88 (5), pp. 625-634. Date of Electronic Publication: 2016 Aug 06.
Typ publikacji:: Editorial; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*chemistry
Gallic Acid/*chemistry
Indans/*chemistry
Tubulin Modulators/*chemistry
Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/toxicity ; Apoptosis/drug effects ; Benzylidene Compounds/chemistry ; Binding Sites ; Biomarkers, Tumor/blood ; Carcinoma, Ehrlich Tumor/drug therapy ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; G2 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Indans/chemical synthesis ; Indans/toxicity ; M Phase Cell Cycle Checkpoints/drug effects ; Mice ; Molecular Docking Simulation ; Protein Structure, Tertiary ; Tubulin/chemistry ; Tubulin/metabolism ; Tubulin Modulators/therapeutic use ; Tubulin Modulators/toxicity

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Skocz do pozycji: 2.

Tytuł:: Cell specific apoptosis by RLX is mediated by NFκB in human colon carcinoma HCT-116 cells.
Autorzy:: Qazi AK
Hussain A
Aga MA
Ali S
Taneja SC
Sharma PR
Saxena AK
Mondhe DM
Hamid A; Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Jammu 180001, India. .; Pokaż więcej
Źródło:: BMC cell biology [BMC Cell Biol] 2014 Oct 10; Vol. 15, pp. 36. Date of Electronic Publication: 2014 Oct 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alkaloids/*chemistry
Alkaloids/*pharmacology
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Colorectal Neoplasms/*drug therapy
NF-kappa B/*metabolism
Acanthaceae/chemistry ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Movement ; Colorectal Neoplasms/metabolism ; Down-Regulation/drug effects ; HCT116 Cells ; Humans ; Membrane Potential, Mitochondrial ; Up-Regulation/drug effects

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Skocz do pozycji: 3.

Tytuł:: Parthenium hysterophorus: a probable source of anticancer, antioxidant and anti-HIV agents.
Autorzy:: Kumar S; Department of Biochemistry, University of Allahabad, Allahabad 211002, India.
Chashoo G; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, Jammu 180001, India.
Saxena AK; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, Jammu 180001, India.
Pandey AK; Department of Biochemistry, University of Allahabad, Allahabad 211002, India.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2013; Vol. 2013, pp. 810734. Date of Electronic Publication: 2013 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-HIV Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Antioxidants/*pharmacology
Plant Extracts/*pharmacology
Cell Cycle/drug effects ; Cell Line, Tumor ; Free Radical Scavengers/pharmacology ; HL-60 Cells ; Humans ; Lipid Peroxidation/drug effects ; MCF-7 Cells ; Membrane Potential, Mitochondrial/drug effects ; Parthenogenesis ; Plant Leaves/chemistry

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Skocz do pozycji: 4.

Tytuł:: 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis.
Autorzy:: Mukherjee A; Department of Anticancer Drug Development, Chittaranjan National Cancer Institute, Kolkata 700026, India.
Dutta S
Shanmugavel M
Mondhe DM
Sharma PR
Singh SK
Saxena AK
Sanyal U; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2010 Dec 31; Vol. 29, pp. 175. Date of Electronic Publication: 2010 Dec 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Cycle/*drug effects
Naphthalimides/*pharmacology
Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans

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Skocz do pozycji: 5.

Tytuł:: Antitumor activity of Nitronaphthal-NU, a novel mixed-function agent.
Autorzy:: Samanta S; Department of Anticancer Drug Development, Chittaranjan National Cancer Institute, Calcutta-700026, India.
Pain A
Dutta S
Saxena AK
Shanmugavel M
Pandita RM
Qazi GN
Sanyal U; Pokaż więcej
Źródło:: Journal of experimental therapeutics & oncology [J Exp Ther Oncol] 2005; Vol. 5 (1), pp. 15-22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Naphthalenes/*chemical synthesis
Naphthalenes/*pharmacology
Alkylation ; Animals ; Antineoplastic Agents/chemical synthesis ; Cell Line, Tumor ; DNA/drug effects ; DNA/metabolism ; DNA, Neoplasm/biosynthesis ; Drug Screening Assays, Antitumor ; Drug Synergism ; Humans ; Imides/therapeutic use ; Isoquinolines/therapeutic use ; Lomustine/therapeutic use ; Mice ; Naphthalimides ; Neoplasm Transplantation ; RNA, Neoplasm/biosynthesis ; Sarcoma 180/metabolism ; Thymidine/metabolism ; Uridine/metabolism

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