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    Wyświetlanie 1-9 z 9
    Tytuł:
    A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl.
    Autorzy:
    Göhring G; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Thomay K; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Schmidt G; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Ripperger T; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Xu M; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.; b Manitoba Institute of Cell Biology , CancerCare Manitoba , Winnipeg , Canada.
    Wittner N; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Chao MM; c Department of Pediatric Hematology and Oncology , Hannover Medical School , Hannover , Germany.
    Baumann I; d Department of Pathology , Clinical Center , Böblingen , Germany.
    Niewisch M; e Division of Pediatric Hematology and Oncology, Department of Pediatrics , University Medical Center Freiburg , Freiburg , Germany.
    Reinhardt D; f Clinic for Pediatrics III , University Hospital Essen , Essen , Germany.
    Klingebiel T; g Hospital for Children and Adolescents , University Hospital Frankfurt , Frankfurt , Germany.
    Thol F; h Department of Hematology, Hemostasis, Oncology and SCT , Hannover Medical School , Hannover , Germany.
    Schlegelberger B; a Institute of Human Genetics , Hannover Medical School , Hannover , Germany.
    Niemeyer CM; e Division of Pediatric Hematology and Oncology, Department of Pediatrics , University Medical Center Freiburg , Freiburg , Germany.
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    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2017 Mar; Vol. 58 (3), pp. 718-721. Date of Electronic Publication: 2016 Nov 28.
    Typ publikacji:
    Letter; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation*
    Clonal Evolution/*genetics
    DNA (Cytosine-5-)-Methyltransferases/*genetics
    Leukemia, Myeloid, Acute/*genetics
    Myelodysplastic Syndromes/*genetics
    Precancerous Conditions/*genetics
    Adolescent ; Alleles ; Biomarkers ; Bone Marrow/pathology ; DNA Methylation ; DNA Methyltransferase 3A ; DNA Mutational Analysis ; Female ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukocyte Count ; Myelodysplastic Syndromes/diagnosis
    Raport
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q.
    Autorzy:
    Heuser M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Meggendorfer M; MLL Munich Leukemia Laboratory, Munich, Germany.
    Cruz MM; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Fabisch J; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Klesse S; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Köhler L; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Göhring G; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
    Ganster C; Department of Hematology and Oncology, Georg-August-Universität Göttingen, Göttingen, Germany.
    Shirneshan K; Department of Hematology and Oncology, Georg-August-Universität Göttingen, Göttingen, Germany.
    Gutermuth A; Department of Hematology and Oncology, Georg-August-Universität Göttingen, Göttingen, Germany.
    Cerny-Reiterer S; Department of Hematology and Hemostasis, Medical University Vienna, Vienna, Austria.
    Krönke J; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
    Panagiota V; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Haferlach C; MLL Munich Leukemia Laboratory, Munich, Germany.
    Koenecke C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Platzbecker U; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Thiede C; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Schroeder T; Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany.
    Kobbe G; Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany.
    Ehrlich S; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Stamer K; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Döhner K; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
    Valent P; Department of Hematology and Hemostasis, Medical University Vienna, Vienna, Austria.
    Schlegelberger B; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
    Kroeger N; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Haase D; Department of Hematology and Oncology, Georg-August-Universität Göttingen, Göttingen, Germany.
    Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany.
    Thol F; MLL Munich Leukemia Laboratory, Munich, Germany.
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    Źródło:
    Leukemia [Leukemia] 2015 Sep; Vol. 29 (9), pp. 1942-5. Date of Electronic Publication: 2015 Feb 24.
    Typ publikacji:
    Letter; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Chromosomes, Human, Pair 5*
    Mutation*
    Casein Kinase Ialpha/*genetics
    Myelodysplastic Syndromes/*genetics
    Myelodysplastic Syndromes/*mortality
    Humans ; Prognosis
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Low frequency of calreticulin mutations in MDS patients.
    Autorzy:
    Heuser M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Panagiota V; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Koenecke C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Fehse B; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Alchalby H; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Badbaran A; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Shahswar R; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Stadler M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Eder M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Göhring G; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
    Trummer A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Schroeder T; Department of Hematology, Oncology and Clinical Immunology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany.
    Kobbe G; Department of Hematology, Oncology and Clinical Immunology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany.
    Thiede C; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Platzbecker U; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Schlegelberger B; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
    Kroeger N; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Thol F; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2014 Sep; Vol. 28 (9), pp. 1933-4. Date of Electronic Publication: 2014 May 21.
    Typ publikacji:
    Letter; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation*
    Calreticulin/*genetics
    Myelodysplastic Syndromes/*genetics
    Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia, Myeloid, Acute/therapy ; Retrospective Studies ; Transplantation, Homologous
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation.
    Autorzy:
    Panagiota V; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Thol F; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Markus B; Department of Cardiology, University Hospital Marburg, Marburg, Germany.
    Fehse B; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Alchalby H; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Badbaran A; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Lehmann U; Institute of Pathology, Hannover Medical School, Hannover, Germany.
    Koenecke C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Shahswar R; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Chaturvedi A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Stadler M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Eder M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Göhring G; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
    Koenigsmann M; Outpatient Oncology Center Hannover, Hannover, Germany.
    Kloos A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Trummer A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Schroeder T; Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany.
    Kobbe G; Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany.
    Thiede C; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Platzbecker U; Medical Department I, University Hospital Carl Gustav Carus, Dresden, Germany.
    Schlegelberger B; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
    Kreipe HH; Institute of Pathology, Hannover Medical School, Hannover, Germany.
    Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Kröger N; Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Heuser M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2014 Jul; Vol. 28 (7), pp. 1552-5. Date of Electronic Publication: 2014 Feb 07.
    Typ publikacji:
    Letter; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation*
    Calreticulin/*genetics
    Primary Myelofibrosis/*genetics
    Primary Myelofibrosis/*mortality
    Graft vs Host Disease/etiology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Primary Myelofibrosis/therapy ; Prognosis ; Transplantation, Homologous ; Treatment Outcome
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications.
    Autorzy:
    Damm F
    Thol F
    Kosmider O
    Kade S
    Löffeld P
    Dreyfus F
    Stamatoullas-Bastard A
    Tanguy-Schmidt A
    Beyne-Rauzy O
    de Botton S
    Guerci-Bresler A
    Göhring G
    Schlegelberger B
    Ganser A
    Bernard OA
    Fontenay M
    Heuser M
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2012 May; Vol. 26 (5), pp. 1137-40. Date of Electronic Publication: 2011 Nov 08.
    Typ publikacji:
    Letter; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation*
    Myelodysplastic Syndromes/*genetics
    Phosphoproteins/*genetics
    Ribonucleoprotein, U2 Small Nuclear/*genetics
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; RNA Splicing Factors ; Young Adult
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Update on cytogenetic and molecular changes in myelodysplastic syndromes.
    Autorzy:
    Schlegelberger B; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany. schlegelberger. />Göhring G
    Thol F
    Heuser M
    Pokaż więcej
    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2012 Apr; Vol. 53 (4), pp. 525-36. Date of Electronic Publication: 2011 Nov 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Chromosome Aberrations*
    Mutation*
    Genetic Predisposition to Disease/*genetics
    Myelodysplastic Syndromes/*genetics
    Humans ; Karyotype ; Myelodysplastic Syndromes/pathology ; Prognosis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia.
    Autorzy:
    Damm F; Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
    Bunke T
    Thol F
    Markus B
    Wagner K
    Göhring G
    Schlegelberger B
    Heil G
    Reuter CW
    Püllmann K
    Schlenk RF
    Döhner K
    Heuser M
    Krauter J
    Döhner H
    Ganser A
    Morgan MA
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2012 Feb; Vol. 26 (2), pp. 289-95. Date of Electronic Publication: 2011 Aug 09.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation*
    Biomarkers, Tumor/*genetics
    Leukemia, Myeloid, Acute/*genetics
    NADH Dehydrogenase/*genetics
    Adult ; Base Sequence ; DNA Primers ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Nucleophosmin ; Polymerase Chain Reaction ; Prognosis ; Risk Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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