- Tytuł:
- Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2013 Dec 27; Vol. 8 (12), pp. e84841. Date of Electronic Publication: 2013 Dec 27 (Print Publication: 2013).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Gene Expression Regulation, Leukemic*
Signal Transduction*
CD4-Positive T-Lymphocytes/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Intracellular Signaling Peptides and Proteins/*biosynthesis
Membrane Proteins/*biosynthesis
Neoplasms, Experimental/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*metabolism
Adaptor Proteins, Signal Transducing ; Animals ; CD4-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/pathology ; Calcium-Binding Proteins ; Intracellular Signaling Peptides and Proteins/genetics ; Membrane Proteins/genetics ; Mice ; Mice, Transgenic ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Receptors, Notch/genetics ; Receptors, Notch/metabolism
Czasopismo naukowe