- Tytuł:
- Attenuation of canonical NF-κB signaling maintains function and stability of human Treg.
- Autorzy:
- Źródło:
- The FEBS journal [FEBS J] 2021 Jan; Vol. 288 (2), pp. 640-662. Date of Electronic Publication: 2020 May 28.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Forkhead Transcription Factors/*immunology
Haploinsufficiency/*immunology
NF-kappa B p50 Subunit/*immunology
T-Lymphocytes, Regulatory/*immunology
TOR Serine-Threonine Kinases/*immunology
Transcription Factor RelA/*immunology
Active Transport, Cell Nucleus/drug effects ; Active Transport, Cell Nucleus/immunology ; Cell Nucleus/drug effects ; Cell Nucleus/immunology ; Cell Nucleus/metabolism ; Forkhead Transcription Factors/genetics ; Gene Expression Regulation ; Humans ; Interleukin-10/genetics ; Interleukin-10/immunology ; Lymphocyte Activation ; NF-kappa B p50 Subunit/deficiency ; NF-kappa B p50 Subunit/genetics ; Phosphorylation/drug effects ; Primary Cell Culture ; Repressor Proteins/genetics ; Repressor Proteins/immunology ; Signal Transduction ; Sirolimus/pharmacology ; T-Lymphocytes, Regulatory/cytology ; T-Lymphocytes, Regulatory/drug effects ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/genetics ; Thiazoles/pharmacology ; Transcription Factor RelA/antagonists & inhibitors ; Transcription Factor RelA/genetics
Czasopismo naukowe