Autor: "Schneekloth JS Jr" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.
Autorzy:: Gaikwad SM; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Phyo Z; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Arteaga AQ; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Gorjifard S; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Calabrese DR; Chemical Biology Laboratory, National Cancer Institute, NIH, Frederick, MD 21702, USA.; NCATS, NIH, Rockville, MD 20850, USA.
Connors D; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Huang J; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Michalowski AM; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Zhang S; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Liu ZG; Laboratory of Immune Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Schneekloth JS Jr; Chemical Biology Laboratory, National Cancer Institute, NIH, Frederick, MD 21702, USA.
Mock BA; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2020 Oct 13; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 13.
Typ publikacji:: Journal Article

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Skocz do pozycji: 2.

Tytuł:: Custom G4 Microarrays Reveal Selective G-Quadruplex Recognition of Small Molecule BMVC: A Large-Scale Assessment of Ligand Binding Selectivity.
Autorzy:: Wu G; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, 575 W Stadium Ave, West Lafayette, IN 47907, USA.
Tillo D; Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Ray S; Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chang TC; Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei 106, Taiwan.
Schneekloth JS Jr; Chemical Biology Laboratory, National Cancer Institute-Frederick, Frederick, MD 21702, USA.
Vinson C; Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Yang D; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, 575 W Stadium Ave, West Lafayette, IN 47907, USA.; Purdue Center for Cancer Research, West Lafayette, IN 47906, USA.; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Jul 30; Vol. 25 (15). Date of Electronic Publication: 2020 Jul 30.
Typ publikacji:: Journal Article
MeSH Terms:: G-Quadruplexes*
Carbazoles/*metabolism
Fluorescent Dyes/*metabolism
Proto-Oncogene Proteins c-myc/*genetics
Pyridinium Compounds/*metabolism
Carbazoles/chemistry ; Fluorescence ; Fluorescent Dyes/chemistry ; Humans ; Ligands ; Microarray Analysis ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-myc/metabolism ; Pyridinium Compounds/chemistry

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Skocz do pozycji: 3.

Tytuł:: Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age.
Autorzy:: Ferreira R; ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, Australian National University, Acton 2601, Australian Capital Territory, Australia.
Schneekloth JS Jr; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Panov KI; ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, Australian National University, Acton 2601, Australian Capital Territory, Australia.; CCRCB and School of Biological Sciences, Queen's University Belfast Medical Biology Centre, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK.
Hannan KM; ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, Australian National University, Acton 2601, Australian Capital Territory, Australia.; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.
Hannan RD; ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, Australian National University, Acton 2601, Australian Capital Territory, Australia.; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.; Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, Victoria 3000, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.; School of Biomedical Sciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Jan 21; Vol. 9 (2). Date of Electronic Publication: 2020 Jan 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Transcription, Genetic*
Neoplasms/*enzymology
Neoplasms/*therapy
RNA Polymerase I/*genetics
Drug Design ; Humans ; Neoplasms/genetics ; Patient Satisfaction ; RNA Polymerase I/metabolism ; Ribosomes/metabolism

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