Autor: "Schober SJ" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing's Sarcoma, Enhancing T Cell Cytotoxicity.
Autorzy:: Biele E; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Schober SJ; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Prexler C; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Thiede M; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Heyking KV; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Gassmann H; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Eck J; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Xue B; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Burdach S; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; German Cancer Consortium (DKTK), German Research Center (DKFZ), Partner Site Munich, 80336 Munich, Germany.
Thiel U; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Nov 08; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Up-Regulation*/genetics
Histocompatibility Antigens Class I/*metabolism
Intercellular Adhesion Molecule-1/*metabolism
Monocytes/*pathology
Sarcoma, Ewing/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Antigens, CD ; Cell Line, Tumor ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Gene Expression Regulation, Neoplastic ; Humans ; Immunoglobulins ; Membrane Glycoproteins ; Sarcoma, Ewing/genetics ; Tumor Necrosis Factor-alpha/metabolism ; CD83 Antigen

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Skocz do pozycji: 2.

Tytuł:: Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function.
Autorzy:: Gassmann H; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Schneider K; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Evdokimova V; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.
Ruzanov P; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.
Schober SJ; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Xue B; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
von Heyking K; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Thiede M; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Richter GHS; Division of Oncology and Hematology, Department of Pediatrics, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Pfaffl MW; Division of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany.
Noessner E; Immunoanalytics Research Group-Tissue Control of Immunocytes, Helmholtz Center, 81377 Munich, Germany.
Stein LD; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.
Sorensen PH; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1L3, Canada.
Burdach SEG; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1L3, Canada.; Translational Pediatric Cancer Research, Institute of Pathology, Technical University of Munich, 80804 Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Partner Site Munich, 81675 Munich, Germany.
Thiel U; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Aug 13; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dendritic Cells/*metabolism
Extracellular Vesicles/*metabolism
Adaptive Immunity ; B7-1 Antigen/metabolism ; Cell Differentiation ; Cell Line ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Extracellular Vesicles/transplantation ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Humans ; Interleukin-10/metabolism ; Interleukin-6/metabolism ; Lymphocyte Activation ; Monocytes/cytology ; Monocytes/metabolism ; Sarcoma, Ewing/metabolism ; Sarcoma, Ewing/pathology ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology ; Transcriptome ; Tumor Microenvironment

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Skocz do pozycji: 3.

Tytuł:: MHC Class I-Restricted TCR-Transgenic CD4 T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo.
Autorzy:: Schober SJ; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Thiede M; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Gassmann H; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Prexler C; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Xue B; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Schirmer D; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.
Wohlleber D; Institute of Molecular Immunology/Experimental Oncology, Klinikum rechts der Isar, Technical University of Munich, 81674 Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU, 80337 Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU, 80337 Munich, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Busch DH; Institute for Medical Microbiology, Immunology and Hygiene, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81674 Munich, Germany.
Richter GHS; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; Division of Oncology and Hematology, Department of Pediatrics, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Burdach SEG; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), partner site Munich, 80336 Munich, Germany.
Thiel U; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804 Munich, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Jun 29; Vol. 9 (7). Date of Electronic Publication: 2020 Jun 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antigens, Neoplasm/*metabolism
CD4-Positive T-Lymphocytes/*metabolism
CD8-Positive T-Lymphocytes/*metabolism
Oxidoreductases/*metabolism
Sarcoma, Ewing/*metabolism
Animals ; Cells, Cultured ; Computational Biology ; DNA-Binding Proteins/metabolism ; Flow Cytometry ; Humans ; Mice, Inbred BALB C ; Mice, Mutant Strains ; Xenograft Model Antitumor Assays

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