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Tytuł:
Patients with Advanced Pancreatic Cancer Treated with Mistletoe and Hyperthermia in Addition to Palliative Chemotherapy: A Retrospective Single-Center Analysis.
Autorzy:
Hohneck AL; Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 69117 Heidelberg, Germany.; European Center for AngioScience (ECAS), German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, 68167 Mannheim, Germany.
Sadikaj L; Onkologische Praxis Kaiserslautern, 67655 Kaiserslautern, Germany.
Heinemann L; Department of Haematology and Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 69117 Heidelberg, Germany.
Schroeder M; Klinik Öschelbronn, 75223 Oeschelbronn, Germany.
Riess H; AnthroMed Öschelbronn, Centrum für Integrative Medizin, 75223 Oeschelbronn, Germany.
Gerhards A; AnthroMed Öschelbronn, Centrum für Integrative Medizin, 75223 Oeschelbronn, Germany.
Burkholder I; Department of Nursing and Health, University of Applied Sciences of the Saarland, 66117 Saarbruecken, Germany.
Heckel-Reusser S; Heckel Medizintechnik GmbH, 73728 Esslingen, Germany.
Gottfried J; Klinik Öschelbronn, 75223 Oeschelbronn, Germany.
Hofheinz RD; Department of Haematology and Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 69117 Heidelberg, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2023 Oct 11; Vol. 15 (20). Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cabotegravir and Rilpivirine Long-Acting Antiretroviral Therapy Administered Every 2 Months is Cost-Effective for the Treatment of HIV-1 in Spain.
Autorzy:
Moreno S; Hospital Ramón y Cajal, CIBERINFEC, Universidad de Alcalá, IRYCIS, Madrid, Spain.
Rivero A; Hospital Reina Sofía, Córdoba, Spain.
Ventayol P; Hospital Son Espases, Palma, Spain.
Falcó V; Hospital Vall d'Hebron, Barcelona, Spain.
Torralba M; Hospital de Guadalajara, Guadalajara, Spain.
Schroeder M; ViiV Healthcare, Brentford, UK.
Neches V; Market Access, GSK, P.T.M Severo Ochoa, 2-28760, Tres Cantos, Madrid, Spain. .
Vallejo-Aparicio LA; Market Access, GSK, P.T.M Severo Ochoa, 2-28760, Tres Cantos, Madrid, Spain.
Mackenzie I; HEOR Ltd, Cardiff, UK.
Turner M; HEOR Ltd, Cardiff, UK.
Harrison C; HEOR Ltd, Cardiff, UK.
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Źródło:
Infectious diseases and therapy [Infect Dis Ther] 2023 Aug; Vol. 12 (8), pp. 2039-2055. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Netrank: network-based approach for biomarker discovery.
Autorzy:
Al-Fatlawi A; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), TU Dresden, Dresden, Germany.; University of Kufa, Najaf, Iraq.
Rusadze E; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.
Shmelkin A; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.
Malekian N; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.
Ozen C; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.
Pilarsky C; Department of Surgical Research, Universitätsklinikum Erlangen, Erlangen, Germany.
Schroeder M; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany. Michael.Schroeder@tu-dresden.de.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), TU Dresden, Dresden, Germany. Michael.Schroeder@tu-dresden.de.
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Jul 29; Vol. 24 (1), pp. 304. Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:
Journal Article
MeSH Terms:
Biomedical Research*
Humans ; Algorithms ; Area Under Curve ; Disease Progression ; Gene Library
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An interaction-based drug discovery screen explains known SARS-CoV-2 inhibitors and predicts new compound scaffolds.
Autorzy:
Schake P; Bioinformatics, Biotechnology Center (BIOTEC), Technische Universität Dresden, Dresden, Saxony, Germany. .
Dishnica K; University of Verona, Verona, Italy.
Kaiser F; PharmAi, Dresden, Germany.
Leberecht C; PharmAi, Dresden, Germany.
Haupt VJ; PharmAi, Dresden, Germany.
Schroeder M; Bioinformatics, Biotechnology Center (BIOTEC), Technische Universität Dresden, Dresden, Saxony, Germany.
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 06; Vol. 13 (1), pp. 9204. Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Pandemics ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; Molecular Docking Simulation ; Viral Nonstructural Proteins/metabolism ; Drug Discovery/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Placenta-A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice.
Autorzy:
Ontsouka E; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Schroeder M; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Ok L; Institut National de la Recherche Scientifique (INRS), Centre Armand Frappier et Regroupement Intersectoriel de Recherche en Santé de l'Université du Quebec (RISUQ), 532 des Prairies, Laval, QC H7V1B7, Canada.
Vaillancourt C; Institut National de la Recherche Scientifique (INRS), Centre Armand Frappier et Regroupement Intersectoriel de Recherche en Santé de l'Université du Quebec (RISUQ), 532 des Prairies, Laval, QC H7V1B7, Canada.
Stroka D; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Murtenstrasse 35, 3002 Bern, Switzerland.
Albrecht C; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 30; Vol. 24 (11). Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Bile Acids and Salts*/metabolism
Steroid 12-alpha-Hydroxylase*/genetics
Humans ; Mice ; Animals ; Pregnancy ; Female ; Liver/metabolism ; Cholesterol/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Placenta/metabolism ; Gene Expression ; Steroid Hydroxylases/genetics ; Steroid Hydroxylases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Reasoning: A Missing Piece for Improving Evidence-Based Assessment in Psychology.
Autorzy:
Wilcox G; School and Applied Child Psychology, Werklund School of Education, University of Calgary, Calgary, AB T2N 1N4, Canada.
Schroeder M; School and Applied Child Psychology, Werklund School of Education, University of Calgary, Calgary, AB T2N 1N4, Canada.
Drefs MA; School and Applied Child Psychology, Werklund School of Education, University of Calgary, Calgary, AB T2N 1N4, Canada.
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Źródło:
Journal of Intelligence [J Intell] 2023 Jan 26; Vol. 11 (2). Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Rad52 SSAP superfamily and new insight into homologous recombination.
Autorzy:
Al-Fatlawi A; Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Tatzberg 47, 01307, Dresden, Germany.
Schroeder M; Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Tatzberg 47, 01307, Dresden, Germany. michael.schroeder@tu-dresden.de.
Stewart AF; Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Tatzberg 47, 01307, Dresden, Germany. .; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia. .
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Źródło:
Communications biology [Commun Biol] 2023 Jan 23; Vol. 6 (1), pp. 87. Date of Electronic Publication: 2023 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Homologous Recombination*
Rad52 DNA Repair and Recombination Protein*/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Emati: a recommender system for biomedical literature based on supervised learning.
Autorzy:
Kart Ö; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany.; Department of Computer Engineering, Dokuz Eylül University, Tinaztepe Campus, Buca 35160 Izmir, Turkey.
Mestiashvili A; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany.
Lachmann K; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany.
Kwasnicki R; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany.
Schroeder M; Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany.
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Źródło:
Database : the journal of biological databases and curation [Database (Oxford)] 2022 Dec 09; Vol. 2022.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bayes Theorem*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
What about the fellow eye in treatment of neovascular age-related macular degeneration? Analysis of data from the Swedish macula register.
Autorzy:
Lövestam Adrian M; Department of Ophthalmology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Schroeder M; Department of Ophthalmology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Westborg I; Department of Neuroscience, Ophthalmology, Uppsala University, Uppsala, Sweden.
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Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2022 Nov; Vol. 100 (7), pp. 769-774. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Macular Degeneration*/drug therapy
Wet Macular Degeneration*/diagnosis
Wet Macular Degeneration*/drug therapy
Wet Macular Degeneration*/epidemiology
Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/therapeutic use ; Female ; Follow-Up Studies ; Humans ; Intravitreal Injections ; Male ; Ranibizumab ; Retrospective Studies ; Sweden/epidemiology ; Tomography, Optical Coherence ; Visual Acuity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of four diagnostic criteria for invasive pulmonary aspergillosis-A diagnostic accuracy study in critically ill patients.
Autorzy:
Schroeder M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Giese M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wijaya C; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Winterland S; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nuechtern A; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Grensemann J; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Matthews H; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wichmann D; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Stamm J; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rohde H; Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christner M; Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ozga AK; Center for Experimental Medicine, Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Steurer S; Center for Diagnostics, Institute of, Pathology with the Sections Molecular Pathology and Cytopathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Heinemann A; Center for Diagnostics, Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Simon M; Department of Respiratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Fischer M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kluge S; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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Źródło:
Mycoses [Mycoses] 2022 Aug; Vol. 65 (8), pp. 824-833. Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Invasive Pulmonary Aspergillosis*/diagnosis
Invasive Pulmonary Aspergillosis*/microbiology
Aspergillus ; Cohort Studies ; Critical Illness ; Humans ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel phenotype associated with the R162W variant in the KCNJ13 gene.
Autorzy:
Schroeder M; Department of Ophthalmology and Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Peter VG; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.
Gränse L; Department of Ophthalmology and Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Andréasson S; Department of Ophthalmology and Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Rivolta C; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.
Kjellström U; Department of Ophthalmology and Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
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Źródło:
Ophthalmic genetics [Ophthalmic Genet] 2022 Aug; Vol. 43 (4), pp. 500-507. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cataract*/genetics
Retinal Detachment*
Retinal Dystrophies*/genetics
DNA Mutational Analysis ; Electroretinography ; Humans ; Mutation ; Pedigree ; Phenotype ; Retinal Degeneration ; Tomography, Optical Coherence/methods
SCR Disease Name:
Snowflake vitreoretinal degeneration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.
Autorzy:
Lee KH; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA.; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, USA.
Ali NF; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA.
Lee SH; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, USA.
Zhang Z; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, PO Box 800546, Charlottesville, VA, 22908, USA.
Burdick M; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, PO Box 800546, Charlottesville, VA, 22908, USA.
Beaulac ZJ; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA.
Petruncio G; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA.
Li L; Department of Obstetrics and Gynecology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, 358 Datong Road, Shanghai, 200137, China.
Xiang J; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Chung EM; STCube Pharmaceutical, Inc., 401 Professional Dr, Gaithersburg, MD, 20879, USA.
Foreman KW; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA.
Noble SM; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, USA. schroeder.m..
Shim YM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, PO Box 800546, Charlottesville, VA, 22908, USA. .
Paige M; Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 08; Vol. 12 (1), pp. 9443. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Epoxide Hydrolases*
Pneumonia*
Animals ; Disease Models, Animal ; Ligands ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploration of real-world outcomes and treatment patterns in patients treated with anti-vascular endothelial growth factors for neovascular age-related macular degeneration in Sweden.
Autorzy:
Schroeder M; Divison of Ophthalmology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
Westborg I; Department of Neuroscience, Ophthalmology, Uppsala University, Uppsala, Sweden.
Fluur C; Novartis Sverige AB, Kista, Sweden.
Olsen R; Novartis Healthcare A/S, Copenhagen, Denmark.
Lövestam-Adrian M; Divison of Ophthalmology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.
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Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2022 Jun; Vol. 100 (4), pp. e928-e935. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Macular Degeneration*/drug therapy
Wet Macular Degeneration*/diagnosis
Wet Macular Degeneration*/drug therapy
Angiogenesis Inhibitors ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Intravitreal Injections ; Ranibizumab ; Retrospective Studies ; Sweden/epidemiology ; Treatment Outcome ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A genome-wide scan of wastewater E. coli for genes under positive selection: focusing on mechanisms of antibiotic resistance.
Autorzy:
Malekian N; Biotechnology Center (BIOTEC), Technische Universität Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Agrawal AA; Biotechnology Center (BIOTEC), Technische Universität Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Berendonk TU; Institute of Hydrobiology, Technische Universität Dresden, 01217, Dresden, Germany.
Al-Fatlawi A; Biotechnology Center (BIOTEC), Technische Universität Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Schroeder M; Biotechnology Center (BIOTEC), Technische Universität Dresden, Tatzberg 47-49, 01307, Dresden, Germany. michael.schroeder@tu-dresden.de.
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Źródło:
Scientific reports [Sci Rep] 2022 May 16; Vol. 12 (1), pp. 8037. Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/metabolism
Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; DNA-Binding Proteins/genetics ; Drug Resistance, Microbial/genetics ; Wastewater
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A multiscale model of the regulation of aquaporin 2 recycling.
Autorzy:
Leberecht C; Biotechnology Center (BIOTEC), TU Dresden, Dresden, 01307, Germany. .; University of Applied Sciences Mittweida, Mittweida, 09648, Germany. .
Schroeder M; Biotechnology Center (BIOTEC), TU Dresden, Dresden, 01307, Germany.
Labudde D; University of Applied Sciences Mittweida, Mittweida, 09648, Germany.
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Źródło:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2022 May 09; Vol. 8 (1), pp. 16. Date of Electronic Publication: 2022 May 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aquaporin 2*/genetics
Aquaporin 2*/metabolism
Cyclic AMP-Dependent Protein Kinases*/metabolism
Biological Transport ; Water/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Decomposing compounds enables reconstruction of interaction fingerprints for structure-based drug screening.
Autorzy:
Adasme MF; Biotechnology Center (BIOTEC), CMCB, Technische Universitat Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Bolz SN; Biotechnology Center (BIOTEC), CMCB, Technische Universitat Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Al-Fatlawi A; Biotechnology Center (BIOTEC), CMCB, Technische Universitat Dresden, Tatzberg 47-49, 01307, Dresden, Germany.
Schroeder M; Biotechnology Center (BIOTEC), CMCB, Technische Universitat Dresden, Tatzberg 47-49, 01307, Dresden, Germany. michael.schroeder@tu-dresden.de.
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Źródło:
Journal of cheminformatics [J Cheminform] 2022 Mar 15; Vol. 14 (1), pp. 17. Date of Electronic Publication: 2022 Mar 15.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isoflurane promotes early spontaneous breathing in ventilated intensive care patients: A post hoc subgroup analysis of a randomized trial.
Autorzy:
Müller-Wirtz LM; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.; Outcomes Research Consortium, Cleveland, Ohio, USA.
Behne F; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.
Kermad A; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.
Wagenpfeil G; Institute for Medical Biometry, Epidemiology and Medical Informatics (IMBEI), Saarland University Faculty of Medicine, Homburg, Germany.
Schroeder M; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.
Sessler DI; Outcomes Research Consortium, Cleveland, Ohio, USA.; Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Volk T; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.; Outcomes Research Consortium, Cleveland, Ohio, USA.
Meiser A; Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center, Saarland University Faculty of Medicine, Homburg, Germany.
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Źródło:
Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2022 Mar; Vol. 66 (3), pp. 354-364. Date of Electronic Publication: 2021 Dec 14.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Hypnotics and Sedatives*/therapeutic use
Isoflurane*/therapeutic use
Propofol*/therapeutic use
Respiration*
Respiration, Artificial*
Critical Care ; Deep Sedation ; Humans ; Intensive Care Units
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Explainable AI to improve acceptance of convolutional neural networks for automatic classification of dopamine transporter SPECT in the diagnosis of clinically uncertain parkinsonian syndromes.
Autorzy:
Nazari M; Faculty of Computer Science and Center for Molecular and Cellular Bioengineering, Technical University Dresden, BiotechDresden, Germany.; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H, 01307, Dresden, Germany.
Kluge A; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H, 01307, Dresden, Germany.
Apostolova I; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Klutmann S; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Kimiaei S; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H, 01307, Dresden, Germany.
Schroeder M; Center for Molecular and Cellular Bioengineering, Technical University Dresden, Dresden, Germany.
Buchert R; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. .
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Mar; Vol. 49 (4), pp. 1176-1186. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine Plasma Membrane Transport Proteins*
Parkinsonian Disorders*/diagnostic imaging
Humans ; Neural Networks, Computer ; Retrospective Studies ; Tomography, Emission-Computed, Single-Photon
Czasopismo naukowe
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Tytuł:
Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients.
Autorzy:
de Buhr N; Department of Biochemistry, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Parplys AC; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Schroeder M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Henneck T; Department of Biochemistry, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Schaumburg B; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Stanelle-Bertram S; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Jarczak D; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Nierhaus A; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Hiller J; Institute for Transfusion Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Peine S; Institute for Transfusion Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Kluge S; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Klingel K; Institute for Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany.
Gabriel G; Leibniz Institute for Experimental Virology, Hamburg, Germany.; Institute for Virology, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
von Köckritz-Blickwede M; Department of Biochemistry, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
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Źródło:
Journal of innate immunity [J Innate Immun] 2022; Vol. 14 (5), pp. 461-476. Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Extracellular Traps*/metabolism
Thrombosis*
Aged ; Deoxyribonuclease I/metabolism ; Female ; Humans ; Male ; Neutrophils/metabolism
Czasopismo naukowe
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Tytuł:
Data-driven identification of diagnostically useful extrastriatal signal in dopamine transporter SPECT using explainable AI.
Autorzy:
Nazari M; Department of Computer Science, Biotech, Technical University Dresden, Dresden, Germany.; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H., 01307, Dresden, Germany.
Kluge A; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H., 01307, Dresden, Germany.
Apostolova I; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Klutmann S; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Kimiaei S; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft M.B.H., 01307, Dresden, Germany.
Schroeder M; Department of Computer Science, Biotech, Technical University Dresden, Dresden, Germany.
Buchert R; Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 25; Vol. 11 (1), pp. 22932. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Image Interpretation, Computer-Assisted*
Neural Networks, Computer*
Tomography, Emission-Computed, Single-Photon*
Brain/*diagnostic imaging
Dopamine Plasma Membrane Transport Proteins/*metabolism
Parkinson Disease/*diagnostic imaging
Radiopharmaceuticals/*administration & dosage
Tropanes/*administration & dosage
Brain/metabolism ; Diagnosis, Differential ; Humans ; Nerve Degeneration ; Parkinson Disease/metabolism ; Predictive Value of Tests ; Radiopharmaceuticals/metabolism ; Reproducibility of Results ; Retrospective Studies ; Tropanes/metabolism
Czasopismo naukowe
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