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Wyszukujesz frazę ""Schumacher, Björn"" wg kryterium: Autor


Tytuł:
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Autorzy:
Garinis GA; MGC Department of Cell Biology and Genetics, Center for Biomedical Genetics, Erasmus Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.
Uittenboogaard LM
Stachelscheid H
Fousteri M
van Ijcken W
Breit TM
van Steeg H
Mullenders LH
van der Horst GT
Brüning JC
Niessen CM
Hoeijmakers JH
Schumacher B
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Źródło:
Nature cell biology [Nat Cell Biol] 2009 May; Vol. 11 (5), pp. 604-15. Date of Electronic Publication: 2009 Apr 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage/*physiology
Growth/*physiology
Longevity/*physiology
Transcription, Genetic/*genetics
Aging/physiology ; Animal Structures/metabolism ; Animals ; DNA/radiation effects ; DNA Repair/physiology ; Gene Expression Profiling ; Growth/radiation effects ; Humans ; Longevity/radiation effects ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Biological ; Neoplasms/etiology ; Neoplasms/genetics ; Oxidative Stress/physiology ; Progeria/genetics ; Progeria/metabolism ; RNA Polymerase II/metabolism ; Rats ; Receptor, IGF Type 1/genetics ; Receptor, IGF Type 1/metabolism ; Receptors, Somatotropin/genetics ; Receptors, Somatotropin/metabolism ; Stress, Physiological/physiology ; Transcription, Genetic/radiation effects ; Ultraviolet Rays
Czasopismo naukowe
Tytuł:
Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.
Autorzy:
Lans H; Department of Genetics, Medical Genetics Center, Erasmus MC, Rotterdam, The Netherlands.
Marteijn JA
Schumacher B
Hoeijmakers JH
Jansen G
Vermeulen W
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Źródło:
PLoS genetics [PLoS Genet] 2010 May 06; Vol. 6 (5), pp. e1000941. Date of Electronic Publication: 2010 May 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Caenorhabditis elegans/*genetics
Caenorhabditis elegans/*growth & development
Chromatin Assembly and Disassembly/*radiation effects
DNA Damage/*radiation effects
DNA Mismatch Repair/*radiation effects
Animals ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Female ; Gene Expression Regulation, Developmental/radiation effects ; Male ; Ultraviolet Rays
Czasopismo naukowe
Tytuł:
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
Autorzy:
Ermolaeva MA; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases, Institute for Genetics, University of Cologne, Zülpicher Strasse 47a, 50674 Cologne, Germany.
Segref A
Dakhovnik A
Ou HL
Schneider JI
Utermöhlen O
Hoppe T
Schumacher B
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Źródło:
Nature [Nature] 2013 Sep 19; Vol. 501 (7467), pp. 416-20. Date of Electronic Publication: 2013 Aug 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage*/genetics
Immunity, Innate*/genetics
Adaptation, Physiological/*physiology
Caenorhabditis elegans/*physiology
Germ Cells/*immunology
Germ Cells/*metabolism
Stress, Physiological/*immunology
Animals ; Caenorhabditis elegans/cytology ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/immunology ; Caenorhabditis elegans Proteins/metabolism ; Enzyme Activation ; Genomic Instability/genetics ; Germ Cells/enzymology ; Hot Temperature ; MAP Kinase Signaling System ; Mitogen-Activated Protein Kinase 1/metabolism ; Oxidative Stress ; Proteasome Endopeptidase Complex/metabolism ; Proteolysis ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł:
Impact of genomic damage and ageing on stem cell function.
Autorzy:
Behrens A; Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3LY, UK, and the School of Medicine, King's College London, Guy's Campus, London, SE1 1UL, UK.
van Deursen JM; Department of Pediatric and Adolescent Medicine and the Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
Rudolph KL; Leibniz Institute of Age Research, Fritz Lipmann Institute e.V., Jena, 07745, Germany, and the Research Group on Molecular Aging, Faculty of Medicine, Friedrich-Schiller-University, Jena, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931 Cologne, and the Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), Institute for Genetics, and Systems Biology of Cologne, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.
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Źródło:
Nature cell biology [Nat Cell Biol] 2014 Mar; Vol. 16 (3), pp. 201-7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
DNA Damage*
Adult Stem Cells/*physiology
Aneuploidy ; Animals ; Cells, Cultured ; Cellular Senescence ; DNA Repair ; Genome, Human ; Humans ; Neoplasms/pathology
Czasopismo naukowe
Tytuł:
DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.
Autorzy:
Mueller MM; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Castells-Roca L; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Babu V; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Ermolaeva MA; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Müller RU; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, 50937 Cologne, Germany.
Frommolt P; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Center for Genomics, University of Cologne, Weyertal 115b, 50931 Cologne, Germany.
Williams AB; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Greiss S; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Schneider JI; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Benzing T; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, 50937 Cologne, Germany.
Schermer B; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, 50937 Cologne, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
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Źródło:
Nature cell biology [Nat Cell Biol] 2014 Dec; Vol. 16 (12), pp. 1168-1179. Date of Electronic Publication: 2014 Nov 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging*
DNA Damage*
Gene Expression Regulation, Developmental*
Caenorhabditis elegans/*growth & development
Caenorhabditis elegans Proteins/*genetics
DNA-Binding Proteins/*genetics
Transcription Factors/*genetics
Animals ; Animals, Genetically Modified ; Caenorhabditis elegans Proteins/biosynthesis ; DNA Repair/genetics ; DNA-Binding Proteins/biosynthesis ; Forkhead Transcription Factors ; Herbicides/pharmacology ; Paraquat/pharmacology ; Signal Transduction/genetics ; Transcription Factors/biosynthesis
Czasopismo naukowe

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