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Wyszukujesz frazę ""Schumacher, Björn"" wg kryterium: Autor


Tytuł :
Molecular pathology of rare progeroid diseases.
Autorzy :
Rieckher M; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Center for Molecular Medicine (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.
Garinis GA; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece; Department of Biology, University of Crete, Heraklion, Crete, Greece.
Schumacher B; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Center for Molecular Medicine (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany. Electronic address: bjoern.schumacher@uni-koeln.de.
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Źródło :
Trends in molecular medicine [Trends Mol Med] 2021 Sep; Vol. 27 (9), pp. 907-922. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
The Aging Skin: From Basic Mechanisms to Clinical Applications.
Autorzy :
Schumacher B; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany; Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne Germany. Electronic address: bjoern.schumacher@uni-koeln.de.
Krieg TM; Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne Germany; Translational Matrix Biology, Medical Faculty, University of Cologne, Cologne Germany.
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2021 Apr; Vol. 141 (4S), pp. 949-950.
Typ publikacji :
Editorial
Opinia redakcyjna
Tytuł :
Principles of the Molecular and Cellular Mechanisms of Aging.
Autorzy :
da Silva PFL; Medical Faculty, Institute for Genome Stability in Ageing and Disease, University of Cologne, Cologne, Germany; Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center, University of Cologne, Cologne, Germany; Center for Molecular Medicine, University of Cologne, Cologne, Germany.
Schumacher B; Medical Faculty, Institute for Genome Stability in Ageing and Disease, University of Cologne, Cologne, Germany; Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center, University of Cologne, Cologne, Germany; Center for Molecular Medicine, University of Cologne, Cologne, Germany. Electronic address: bjoern.schumacher@uni-koeln.de.
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2021 Apr; Vol. 141 (4S), pp. 951-960. Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
DNA Damaged Induced Cell Death in Oocytes.
Autorzy :
Gebel J; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, 60438 Frankfurt, Germany.
Tuppi M; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, 60438 Frankfurt, Germany.
Sänger N; Department for Gynecological Endocrinology and Reproductive Medicine, University Hospital of Bonn, Venusberg-Campus 1, 53217 Bonn, Germany.
Schumacher B; Institute for Genome Stability in Aging and Disease, Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center, and Center for Molecular Medicine, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Dötsch V; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, 60438 Frankfurt, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 03; Vol. 25 (23). Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Death/*genetics
DNA Damage/*genetics
Oocytes/*physiology
Animals ; DNA Breaks, Double-Stranded ; DNA Repair/genetics ; Humans
Czasopismo naukowe
Tytuł :
H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage.
Autorzy :
Wang S; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Meyer DH; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany. bjoern.schumacher@uni-koeln.de.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany. bjoern.schumacher@uni-koeln.de.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. bjoern.schumacher@uni-koeln.de.
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Dec; Vol. 27 (12), pp. 1165-1177. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair*/radiation effects
Gene Expression Regulation, Developmental*
Caenorhabditis elegans/*genetics
DNA, Helminth/*genetics
Histones/*genetics
Animals ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans/radiation effects ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Clutch Size/radiation effects ; DNA Damage ; DNA, Helminth/metabolism ; Histones/antagonists & inhibitors ; Histones/metabolism ; Homeostasis/radiation effects ; Longevity/radiation effects ; Oxidoreductases, N-Demethylating/genetics ; Oxidoreductases, N-Demethylating/metabolism ; Protein Biosynthesis/radiation effects ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
A C. elegans model for neurodegeneration in Cockayne syndrome.
Autorzy :
Lopes AFC; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Bozek K; Center for Molecular Medicine (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Robert-Koch-Str. 21, 50931 Cologne, Germany.
Herholz M; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, D-50931 Cologne, Germany.
Trifunovic A; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Center for Molecular Medicine (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Robert-Koch-Str. 21, 50931 Cologne, Germany.; Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, D-50931 Cologne, Germany.
Rieckher M; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Schumacher B; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.; Center for Molecular Medicine (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Robert-Koch-Str. 21, 50931 Cologne, Germany.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 10973-10985.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cockayne Syndrome*/genetics
Cockayne Syndrome*/physiopathology
DNA Damage*
Disease Models, Animal*
Animals ; Caenorhabditis elegans/genetics ; DNA Repair ; DNA Repair Enzymes/genetics ; Mitochondria/pathology ; Mutation ; Poly-ADP-Ribose Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
DNA Damage Response and Metabolic Reprogramming in Health and Disease.
Autorzy :
Chatzidoukaki O; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Crete, Greece.
Goulielmaki E; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Crete, Greece.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD) and Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany.
Garinis GA; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Crete, Greece; Department of Biology, University of Crete, Heraklion, Crete, Greece. Electronic address: .
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Źródło :
Trends in genetics : TIG [Trends Genet] 2020 Oct; Vol. 36 (10), pp. 777-791. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Aging*
Cellular Reprogramming*
Cellular Senescence*
DNA Damage*
DNA Repair*
DNA Repair Enzymes/*metabolism
Neoplasms/*genetics
Animals ; DNA Repair Enzymes/genetics ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
DNA damage responses in ageing.
Autorzy :
da Silva PFL; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.
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Źródło :
Open biology [Open Biol] 2019 Nov 29; Vol. 9 (11), pp. 190168. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Aging*
DNA Damage*
DNA Repair*
Animals ; Cellular Senescence ; Genomic Instability ; Humans ; Longevity ; Stress, Physiological
Czasopismo naukowe
Tytuł :
Age is in the nucleus.
Autorzy :
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany. bjoern.schumacher@uni-koeln.de.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany. bjoern.schumacher@uni-koeln.de.
Vijg J; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. .; Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Źródło :
Nature metabolism [Nat Metab] 2019 Oct; Vol. 1 (10), pp. 931-932.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstream of the Core Apoptotic Machinery in Caenorhabditis elegans .
Autorzy :
Doll MA; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.
Soltanmohammadi N; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany bjoern.schumacher@uni-koeln.de.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.
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Źródło :
Genetics [Genetics] 2019 Sep; Vol. 213 (1), pp. 173-194. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
DNA Damage*
Argonaute Proteins/*metabolism
Caenorhabditis elegans Proteins/*metabolism
MicroRNAs/*genetics
Mitogen-Activated Protein Kinase 1/*metabolism
Animals ; Argonaute Proteins/genetics ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; MAP Kinase Signaling System ; MicroRNAs/metabolism
Czasopismo naukowe
Tytuł :
Recent advances in understanding the mechanisms determining longevity.
Autorzy :
Bayersdorf R; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Schumacher B; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
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Źródło :
F1000Research [F1000Res] 2019 Aug 09; Vol. 8. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Damage*
Longevity*
Signal Transduction*
Aging/*physiology
Humans
Czasopismo naukowe
Tytuł :
Restoration of Proteostasis in the Endoplasmic Reticulum Reverses an Inflammation-Like Response to Cytoplasmic DNA in Caenorhabditis elegans .
Autorzy :
Williams AB; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.; Systems Biology of Ageing Cologne, University of Cologne, 50931, Germany.
Heider F; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.; Systems Biology of Ageing Cologne, University of Cologne, 50931, Germany.
Messling JE; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.; Systems Biology of Ageing Cologne, University of Cologne, 50931, Germany.
Rieckher M; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.; Systems Biology of Ageing Cologne, University of Cologne, 50931, Germany.
Bloch W; Department of Molecular and Cellular Sports Medicine, German Sports University, 50933 Cologne, Germany.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, 50931, Germany bjoern.schumacher@uni-koeln.de.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Germany.; Systems Biology of Ageing Cologne, University of Cologne, 50931, Germany.
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Źródło :
Genetics [Genetics] 2019 Aug; Vol. 212 (4), pp. 1259-1278. Date of Electronic Publication: 2019 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*
Proteostasis*
DNA/*immunology
Endoplasmic Reticulum/*metabolism
Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Endodeoxyribonucleases/genetics ; Endodeoxyribonucleases/metabolism
Czasopismo naukowe
Tytuł :
Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells.
Autorzy :
Ou HL; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Kim CS; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany; Paul Gerson Unna Group 'Skin Homeostasis and Ageing,' Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, D-50931 Cologne, Germany.
Uszkoreit S; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.
Wickström SA; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany; Paul Gerson Unna Group 'Skin Homeostasis and Ageing,' Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, D-50931 Cologne, Germany; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, FI-00014 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, FI-00014 Helsinki, Finland.
Schumacher B; Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany. Electronic address: bjoern.schumacher@uni-koeln.de.
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Źródło :
Developmental cell [Dev Cell] 2019 Jul 22; Vol. 50 (2), pp. 167-183.e8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Caenorhabditis elegans Proteins/*metabolism
Eukaryotic Initiation Factors/*metabolism
Fibroblast Growth Factors/*metabolism
Germ Cells/*pathology
Tumor Suppressor Protein p53/*metabolism
Animals ; Apoptosis ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Cells, Cultured ; DNA Repair ; Eukaryotic Initiation Factors/genetics ; Female ; Germ Cells/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Signal Transduction ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe

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