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    Wyświetlanie 1-19 z 19
    Tytuł:
    Novel urine biomarkers to distinguish UTI from culture-negative pyuria.
    Autorzy:
    Hill EB; Division of Emergency Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA. .; Division of Emergency Medicine, Children's National Health System, The George Washington University School of Medicine, Washington, DC, USA. .
    Watson JR; Division of Infectious Diseases, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
    Cohen DM; Division of Emergency Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
    Kline D; Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University College of Medicine, Columbus, OH, USA.
    Schwaderer AL; Division of Nephrology, Riley Children's Health, Indiana University School of Medicine, Indianapolis, IN, USA.
    Spencer JD; Division of Nephrology and Hypertension, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
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    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2022 Feb; Vol. 37 (2), pp. 385-391. Date of Electronic Publication: 2021 Jul 16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Pyuria*/diagnosis
    Urinary Tract Infections*/diagnosis
    Urinary Tract Infections*/urine
    Biomarkers ; Child ; Humans ; Leukocyte Count ; Urinalysis/methods ; Urine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice.
    Autorzy:
    Hains DS; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
    Polley S; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
    Liang D; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
    Saxena V; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
    Arregui S; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
    Ketz J; The Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
    Barr-Beare E; Brown University, Providence, Rhode Island, USA.
    Rawson A; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
    Spencer JD; The Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
    Cohen A; The Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
    Hansen PL; Lundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Tuttolomondo M; Lundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Casella C; Lundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Ditzel HJ; Lundbeckfonden Center of Excellence NanoCAN, University of Southern Denmark, Odense, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Cohen D; Emergency Department, Nationwide Children's Hospital, Columbus, Ohio, USA.
    Hollox EJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
    Schwaderer AL; Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
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    Źródło:
    Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e477.
    Typ publikacji:
    Letter; Research Support, N.I.H., Extramural
    MeSH Terms:
    Calcium-Binding Proteins/*genetics
    DNA-Binding Proteins/*genetics
    Tumor Suppressor Proteins/*genetics
    Urinary Tract Infections/*pathology
    Animals ; Anti-Bacterial Agents/therapeutic use ; Calcium-Binding Proteins/deficiency ; Case-Control Studies ; Child ; DNA Copy Number Variations ; DNA-Binding Proteins/deficiency ; Disease Models, Animal ; Genetic Predisposition to Disease ; Humans ; Mice ; Mice, Knockout ; Risk Factors ; Tumor Suppressor Proteins/deficiency ; Urinary Tract/metabolism ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/genetics
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Aptamer based proteomic pilot study reveals a urine signature indicative of pediatric urinary tract infections.
    Autorzy:
    Dong L; Department of Pediatrics, Indiana University, Indianapolis, Indiana, United States of America.
    Watson J; Division of Infectious Disease, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
    Cao S; Department of Biostatistics, Indiana University, Indianapolis, Indiana, United States of America.
    Arregui S; Department of Pediatrics, Indiana University, Indianapolis, Indiana, United States of America.
    Saxena V; Department of Pediatrics, Indiana University, Indianapolis, Indiana, United States of America.
    Ketz J; The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America.
    Awol AK; Earlham College, Richmond, Indiana, United States of America.
    Cohen DM; Division of Emergency Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
    Caterino JM; Division of Emergency Medicine, The Ohio State University, Columbus, Ohio, United States of America.
    Hains DS; Department of Pediatrics, Indiana University, Indianapolis, Indiana, United States of America.
    Schwaderer AL; Department of Pediatrics, Indiana University, Indianapolis, Indiana, United States of America.
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    Źródło:
    PloS one [PLoS One] 2020 Jul 06; Vol. 15 (7), pp. e0235328. Date of Electronic Publication: 2020 Jul 06 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
    MeSH Terms:
    Support Vector Machine*
    Aptamers, Nucleotide/*chemistry
    Proteomics/*methods
    Urinalysis/*methods
    Urinary Tract Infections/*diagnosis
    Adolescent ; Biomarkers/urine ; Child ; Child, Preschool ; Female ; Humans ; Male ; Pilot Projects ; Prospective Studies ; Urinary Tract Infections/urine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Publisher Correction: Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function.
    Autorzy:
    Saxena V; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
    Fitch J; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.
    Ketz J; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.
    White P; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Wetzel A; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.
    Chanley MA; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.
    Spencer JD; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Becknell B; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Pierce KR; Innate Immunity Translational Research Center, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, United States.
    Arregui SW; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States.
    Nelson RD; Division of Nephrology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States.
    Schwartz GJ; University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, New York, United States.
    Velazquez V; Research Institute at Nationwide Children's Hospital Flow Cytometry Core Laboratory, Columbus, Ohio, United States.
    Walker LA; Department of Physics, College of Arts and Sciences, The Ohio State University, Columbus, Ohio, United States.
    Chen X; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States.
    Yan P; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States.; Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.
    Hains DS; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
    Schwaderer AL; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Mar 17; Vol. 10 (1), pp. 5090. Date of Electronic Publication: 2020 Mar 17.
    Typ publikacji:
    Published Erratum
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    DNA copy number variations in children with vesicoureteral reflux and urinary tract infections.
    Autorzy:
    Liang D; Department of Pediatrics, Indiana University, Indianapolis, IN, United States of America.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, United States of America.
    McHugh KM; Division of Anatomy, The Ohio State University, Columbus, OH, United States of America.
    Brophy PD; Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, United States of America.
    Shaikh N; Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, United States of America.
    Manak JR; Departments of Biology and Pediatrics, University of Iowa, Iowa City, IA, United States of America.
    Andrews P; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States of America.
    Hakker I; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States of America.
    Wang Z; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States of America.
    Schwaderer AL; Department of Pediatrics, Indiana University, Indianapolis, IN, United States of America.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, United States of America.; Riley Hospital for Children at Indiana University Health, Indianapolis, IN, United States of America.
    Hains DS; Department of Pediatrics, Indiana University, Indianapolis, IN, United States of America.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, United States of America.; Riley Hospital for Children at Indiana University Health, Indianapolis, IN, United States of America.
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    Źródło:
    PloS one [PLoS One] 2019 Aug 12; Vol. 14 (8), pp. e0220617. Date of Electronic Publication: 2019 Aug 12 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    DNA Copy Number Variations/*genetics
    Genetic Predisposition to Disease/*genetics
    Urinary Tract Infections/*genetics
    Vesico-Ureteral Reflux/*genetics
    Case-Control Studies ; Child ; Female ; Genetic Linkage ; Humans ; Immunity, Innate/genetics ; Male ; Risk Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function.
    Autorzy:
    Saxena V; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
    Fitch J; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.
    Ketz J; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.
    White P; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Wetzel A; The Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States.
    Chanley MA; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.
    Spencer JD; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Becknell B; The Research Institute at Nationwide Children's, Center for Clinical and Translational Research, Columbus, Ohio, and College of Medicine, Ohio State University, Columbus, Ohio, United States.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio, United States.
    Pierce KR; Innate Immunity Translational Research Center, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, United States.
    Arregui SW; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States.
    Nelson RD; Division of Nephrology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States.
    Schwartz GJ; University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, New York, United States.
    Velazquez V; Research Institute at Nationwide Children's Hospital Flow Cytometry Core Laboratory, Columbus, Ohio, United States.
    Walker LA; Department of Physics, College of Arts and Sciences, The Ohio State University, Columbus, Ohio, United States.
    Chen X; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States.
    Yan P; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States.; Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.
    Hains DS; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
    Schwaderer AL; Indiana University School of Medicine, Riley Children's Hospital, Indianapolis, Indiana, United States. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jan 24; Vol. 9 (1), pp. 545. Date of Electronic Publication: 2019 Jan 24.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Epithelial Cells/*metabolism
    Gene Expression Profiling/*methods
    Kidney Tubules, Collecting/*cytology
    Kidney Tubules, Collecting/*immunology
    Lipopolysaccharides/*metabolism
    Retinoid X Receptor alpha/*antagonists & inhibitors
    Retinoid X Receptor alpha/*metabolism
    Animals ; Aquaporin 2/genetics ; Aquaporin 2/metabolism ; Female ; Immunity, Innate/genetics ; Interleukin-1/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Pilot Projects ; Signal Transduction/genetics ; Transcriptome/immunology ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Geobiology reveals how human kidney stones dissolve in vivo.
    Autorzy:
    Sivaguru M; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Carl Zeiss , Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign, Urbana, IL, USA. .
    Saw JJ; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Department of Molecular and Integrative Physiology, University of Illinois at Urbana- Champaign, Urbana, IL, USA. .; Mayo Clinic School of Medicine, Mayo Clinic, Rochester, MN, USA. .
    Williams JC Jr; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
    Lieske JC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
    Krambeck AE; Department of Urology, Mayo Clinic, Rochester, MN, USA.; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA.
    Romero MF; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
    Chia N; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
    Schwaderer AL; Department of Pediatric Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA.
    Alcalde RE; Civil, Architectural and Environmental Engineering, University of Texas at Austin, Austin, TX, USA.
    Bruce WJ; Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA.
    Wildman DE; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Molecular and Integrative Physiology, University of Illinois at Urbana- Champaign, Urbana, IL, USA.
    Fried GA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Carl Zeiss , Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign, Urbana, IL, USA.
    Werth CJ; Civil, Architectural and Environmental Engineering, University of Texas at Austin, Austin, TX, USA.
    Reeder RJ; Department of Geosciences, Stony Brook University, Stony Brook, NY, 11794, USA.
    Yau PM; Protein Sciences, Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
    Sanford RA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Geology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
    Fouke BW; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Carl Zeiss , Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Department of Geology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .; Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, USA. .
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2018 Sep 13; Vol. 8 (1), pp. 13731. Date of Electronic Publication: 2018 Sep 13.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Calcium Oxalate/*chemistry
    Kidney/*chemistry
    Kidney Calculi/*chemistry
    Kidney Calculi/*therapy
    Calcium Oxalate/adverse effects ; Crystallization ; Humans ; Kidney/diagnostic imaging ; Kidney/pathology ; Kidney/ultrastructure ; Kidney Calculi/pathology ; Kidney Calculi/ultrastructure ; Microscopy, Confocal ; Minerals/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Acute Kidney Injury and Atypical Features during Pediatric Poststreptococcal Glomerulonephritis.
    Autorzy:
    Ayoob RM; Division of Nephrology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
    Schwaderer AL; Division of Nephrology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
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    Źródło:
    International journal of nephrology [Int J Nephrol] 2016; Vol. 2016, pp. 5163065. Date of Electronic Publication: 2016 Aug 23.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Expression and Significance of the HIP/PAP and RegIIIγ Antimicrobial Peptides during Mammalian Urinary Tract Infection.
    Autorzy:
    Spencer JD; Division of Nephrology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Center for Clinical and Translational Research, Research Institute at Nationwide Children's, Columbus, Ohio, United States of America.
    Jackson AR; Biomedical Sciences Graduate Program, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.
    Li B; Center for Clinical and Translational Research, Research Institute at Nationwide Children's, Columbus, Ohio, United States of America.
    Ching CB; Division of Urology, Department of Surgery, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.
    Vonau M; Department of Pediatrics and Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.
    Easterling RS; Medical College of Ohio, Toledo, Ohio, United States of America.
    Schwaderer AL; Division of Nephrology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Center for Clinical and Translational Research, Research Institute at Nationwide Children's, Columbus, Ohio, United States of America.
    McHugh KM; Department of Anatomy, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Center for Molecular and Human Genetics, Research Institute at Nationwide Children's, Columbus, Ohio, United States of America.
    Becknell B; Division of Nephrology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Center for Clinical and Translational Research, Research Institute at Nationwide Children's, Columbus, Ohio, United States of America.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2015 Dec 10; Vol. 10 (12), pp. e0144024. Date of Electronic Publication: 2015 Dec 10 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Antimicrobial Cationic Peptides/*metabolism
    Peptides/*metabolism
    Animals ; Antimicrobial Cationic Peptides/genetics ; Antimicrobial Cationic Peptides/urine ; Cystitis/metabolism ; Cystitis/microbiology ; Cystitis/pathology ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Humans ; Kidney/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pancreatitis-Associated Proteins ; Peptides/genetics ; Peptides/urine ; RNA/analysis ; RNA/isolation & purification ; Real-Time Polymerase Chain Reaction ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/pharmacology ; Staphylococcus saprophyticus/drug effects ; Transcriptome ; Urinary Bladder/metabolism ; Urinary Tract Infections/metabolism ; Urinary Tract Infections/microbiology ; Urinary Tract Infections/pathology ; Uropathogenic Escherichia coli/drug effects ; Urothelium/metabolism ; Urothelium/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The Interaction between Enterobacteriaceae and Calcium Oxalate Deposits.
    Autorzy:
    Barr-Beare E; The Research Institute at Nationwide Children's Hospital, Center for Clinical and Translational Research, Columbus, Ohio, United States of America.
    Saxena V; The Research Institute at Nationwide Children's Hospital, Center for Clinical and Translational Research, Columbus, Ohio, United States of America.
    Hilt EE; Loyola University Chicago, Stritch School of Medicine, Department of Microbiology and Immunology, Chicago, Illinois, United States of America.
    Thomas-White K; Loyola University Chicago, Stritch School of Medicine, Department of Microbiology and Immunology, Chicago, Illinois, United States of America.
    Schober M; Nationwide Children's Hospital, Division of Urology, Columbus, Ohio, United States of America.
    Li B; The Research Institute at Nationwide Children's Hospital, Center for Clinical and Translational Research, Columbus, Ohio, United States of America.
    Becknell B; The Research Institute at Nationwide Children's Hospital, Center for Clinical and Translational Research, Columbus, Ohio, United States of America; Nationwide Children's Hospital, Division of Nephrology, Columbus, Ohio, United States of America.
    Hains DS; Lebonheur Children's Hospital, Division of Nephrology, Memphis, Tennessee, United States of America.
    Wolfe AJ; Loyola University Chicago, Stritch School of Medicine, Department of Microbiology and Immunology, Chicago, Illinois, United States of America.
    Schwaderer AL; Loyola University Chicago, Stritch School of Medicine, Department of Microbiology and Immunology, Chicago, Illinois, United States of America; Nationwide Children's Hospital, Division of Nephrology, Columbus, Ohio, United States of America.
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    Źródło:
    PloS one [PLoS One] 2015 Oct 08; Vol. 10 (10), pp. e0139575. Date of Electronic Publication: 2015 Oct 08 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Calcium Oxalate/*metabolism
    Enterobacteriaceae/*metabolism
    Adolescent ; Animals ; Child ; DNA, Bacterial/chemistry ; Disease Models, Animal ; Enterobacteriaceae/genetics ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Female ; Glyoxylates/administration & dosage ; Humans ; Kidney/immunology ; Kidney/metabolism ; Kidney Calculi/etiology ; Kidney Calculi/metabolism ; Kidney Calculi/microbiology ; Male ; Mice ; Mice, Inbred C57BL ; Pyelonephritis/etiology ; RNA, Ribosomal, 16S/chemistry ; RNA, Ribosomal, 16S/genetics ; Risk Factors ; Sequence Analysis, DNA ; Urolithiasis/etiology ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The innate immune response during urinary tract infection and pyelonephritis.
    Autorzy:
    Spencer JD; Department of Pediatrics, Division of Nephrology, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA, .
    Schwaderer AL
    Becknell B
    Watson J
    Hains DS
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2014 Jul; Vol. 29 (7), pp. 1139-49. Date of Electronic Publication: 2013 Jun 05.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Review
    MeSH Terms:
    Pyelonephritis/*immunology
    Urinary Tract Infections/*immunology
    Adaptive Immunity ; Antimicrobial Cationic Peptides/physiology ; Cytokines/physiology ; Humans ; Immunity, Innate ; Pyelonephritis/microbiology ; Toll-Like Receptors/physiology ; Urinary Tract/immunology ; Urinary Tract Infections/microbiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract.
    Autorzy:
    Becknell B; Section of Nephrology, Nationwide Children's Hospital, Columbus, Ohio, United States of America ; Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America.
    Spencer JD
    Carpenter AR
    Chen X
    Singh A
    Ploeger S
    Kline J
    Ellsworth P
    Li B
    Proksch E
    Schwaderer AL
    Hains DS
    Justice SS
    McHugh KM
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2013 Oct 21; Vol. 8 (10), pp. e77714. Date of Electronic Publication: 2013 Oct 21 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Anti-Infective Agents/*metabolism
    Urinary Tract/*metabolism
    Urinary Tract/*microbiology
    beta-Defensins/*genetics
    beta-Defensins/*metabolism
    Animals ; Escherichia coli Infections/metabolism ; Escherichia coli Infections/prevention & control ; Female ; Humans ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Mice, Knockout ; Uropathogenic Escherichia coli/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human alpha defensin 5 expression in the human kidney and urinary tract.
    Autorzy:
    Spencer JD; Pediatric Nephrology Fellowship Program, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
    Hains DS
    Porter E
    Bevins CL
    DiRosario J
    Becknell B
    Wang H
    Schwaderer AL
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31712. Date of Electronic Publication: 2012 Feb 16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Kidney/*metabolism
    Urinary Tract Infections/*metabolism
    alpha-Defensins/*analysis
    Escherichia coli Infections ; Humans ; Kidney/chemistry ; Kidney Tubules, Collecting/chemistry ; Kidney Tubules, Collecting/metabolism ; Polymerase Chain Reaction ; Pyelonephritis/metabolism ; Urinary Tract/chemistry ; Urinary Tract/metabolism ; Urothelium/chemistry ; Urothelium/metabolism ; alpha-Defensins/genetics ; alpha-Defensins/urine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Hepatoblastoma and prune belly syndrome: a potential association.
    Autorzy:
    Becknell B; Department of Pediatrics, Ohio State University College of Medicine, Columbus, OH 43205, USA. />Pais P
    Onimoe G
    Rangarajan H
    Schwaderer AL
    McHugh K
    Ranalli MA
    Hains DS
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2011 Aug; Vol. 26 (8), pp. 1269-73. Date of Electronic Publication: 2011 May 20.
    Typ publikacji:
    Case Reports; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hepatoblastoma/*complications
    Liver Neoplasms/*complications
    Prune Belly Syndrome/*complications
    Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Management and etiology of the unilateral multicystic dysplastic kidney: a review.
    Autorzy:
    Hains DS; Department of Pediatrics, Division of Pediatric Nephrology, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA.
    Bates CM
    Ingraham S
    Schwaderer AL
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2009 Feb; Vol. 24 (2), pp. 233-41. Date of Electronic Publication: 2008 May 15.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Multicystic Dysplastic Kidney*/diagnosis
    Multicystic Dysplastic Kidney*/etiology
    Multicystic Dysplastic Kidney*/therapy
    Kidney/*abnormalities
    Child ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Low bone density in children with hypercalciuria and/or nephrolithiasis.
    Autorzy:
    Schwaderer AL; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA. />Cronin R
    Mahan JD
    Bates CM
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2008 Dec; Vol. 23 (12), pp. 2209-14. Date of Electronic Publication: 2008 Aug 12.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bone Density/*physiology
    Hypercalciuria/*physiopathology
    Nephrolithiasis/*physiopathology
    Absorptiometry, Photon ; Child ; Creatinine/urine ; Female ; Humans ; Hypercalciuria/urine ; Male ; Nephrolithiasis/urine ; Quaternary Ammonium Compounds/urine ; Retrospective Studies ; Risk Factors ; Sex Characteristics ; Urinary Calculi/epidemiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Renal anomalies in family members of infants with bilateral renal agenesis/adysplasia.
    Autorzy:
    Schwaderer AL; Division of Nephrology, Department of Pediatrics, Columbus Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA. />Bates CM
    McHugh KM
    McBride KL
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2007 Jan; Vol. 22 (1), pp. 52-6. Date of Electronic Publication: 2006 Sep 15.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Family*
    Congenital Abnormalities/*genetics
    Kidney/*abnormalities
    Kidney Diseases/*congenital
    Cohort Studies ; Congenital Abnormalities/epidemiology ; Extracellular Matrix Proteins/genetics ; Female ; Humans ; Infant, Newborn ; Intracellular Signaling Peptides and Proteins/genetics ; Kidney/diagnostic imaging ; Kidney Diseases/epidemiology ; Kidney Failure, Chronic/etiology ; Male ; Mutation/genetics ; Nerve Tissue Proteins/genetics ; Nuclear Proteins/genetics ; Prevalence ; Protein Tyrosine Phosphatases/genetics ; Ultrasonography
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Granulomatous interstitial nephritis associated with bone marrow transplantation.
    Autorzy:
    Schwaderer AL; Division of Pediatric Nephrology, Golisano Children's Hospital at Strong, Department of Pediatrics, University of Rochester, Rochester, New York, USA. andrew_schwaderer@urmc.rochester.edu
    Arend L
    Lande MB
    Pokaż więcej
    Źródło:
    Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2005 Apr; Vol. 20 (4), pp. 539-42. Date of Electronic Publication: 2005 Feb 03.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Bone Marrow Transplantation/*adverse effects
    Granuloma/*etiology
    Nephritis, Interstitial/*etiology
    Severe Combined Immunodeficiency/*surgery
    Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Chromosomes, Human, X ; Genetic Linkage ; Granuloma/pathology ; Humans ; Kidney/diagnostic imaging ; Kidney/pathology ; Male ; Nephritis, Interstitial/diagnostic imaging ; Nephritis, Interstitial/drug therapy ; Nephritis, Interstitial/pathology ; Severe Combined Immunodeficiency/genetics ; Ultrasonography
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-19 z 19

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