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Tytuł :
Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids.
Autorzy :
Li P; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Li Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Wang Y; School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Liu J; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Lavrijsen M; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Li Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Zhang R; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Verstegen MMA; Department of Surgery, Erasmus MC Transplant Institute, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Wang Y; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Li TC; Department of Virology II, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
Ma Z; Biomedical Research Center, Northwest Minzu University, Lanzhou, PR China.
Kainov DE; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim 7028, Norway.; Institute of Technology, University of Tartu, Tartu 50090, Estonia.
Bruno MJ; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
de Man RA; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
van der Laan LJW; Department of Surgery, Erasmus MC Transplant Institute, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Peppelenbosch MP; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
Pan Q; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, Netherlands.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj5908. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling.
Autorzy :
Marcogliese PC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Dutta D; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Ray SS; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.
Dang NDP; Department of Pharmacology and Toxicology, University of Alabama, Birmingham, AL 35294, USA.
Zuo Z; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Wang Y; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Lu D; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Fazal F; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Ravenscroft TA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Chung H; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Kanca O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Wan J; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Douine ED; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
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Pena LDM; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Yamamoto S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.
Nelson SF; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Might M; Precision Medicine Institute, University of Alabama, Birmingham, AL 35294, USA.
Meyer KC; The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.; Department of Pediatrics, The Ohio State University, Columbus, OH 43210, USA.
Yeo NC; Department of Pharmacology and Toxicology, University of Alabama, Birmingham, AL 35294, USA.; Precision Medicine Institute, University of Alabama, Birmingham, AL 35294, USA.
Bellen HJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabl5613. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Lack of practical identifiability may hamper reliable predictions in COVID-19 epidemic models.
Autorzy :
Gallo L; Department of Physics and Astronomy, University of Catania, Catania 95125, Italy.; INFN Sezione di Catania, Via S. Sofia, 64, Catania 95125, Italy.
Frasca M; Department of Electrical, Electronics and Computer Science Engineering, University of Catania, Catania 95125, Italy.; Istituto di Analisi dei Sistemi ed Informatica 'A. Ruberti,' Consiglio Nazionale delle Ricerche (IASI-CNR), 00185 Roma 00185, Italy.
Latora V; Department of Physics and Astronomy, University of Catania, Catania 95125, Italy.; INFN Sezione di Catania, Via S. Sofia, 64, Catania 95125, Italy.; School of Mathematical Sciences, Queen Mary University of London, London E1 4NS, UK.; Complexity Science Hub Vienna, A-1080 Vienna, Austria.
Russo G; Department of Mathematics and Computer Science, University of Catania, Catania 95125, Italy.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabg5234. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B.
Autorzy :
Liu J; Department of Medicine, University of Toronto, Toronto, ON, Canada.
Budylowski P; Department of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
Samson R; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Griffin BD; Sunnybrook Research Institute, Toronto, ON, Canada.
Babuadze G; Sunnybrook Research Institute, Toronto, ON, Canada.
Rathod B; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Colwill K; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Abioye JA; Providence Therapeutics Holdings Inc., Calgary, AB, Canada.
Schwartz JA; Providence Therapeutics Holdings Inc., Calgary, AB, Canada.
Law R; Department of Immunology, University of Toronto, Toronto, ON, Canada.
Yip L; Sunnybrook Research Institute, Toronto, ON, Canada.
Ahn SK; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Chau S; Department of Immunology, University of Toronto, Toronto, ON, Canada.
Naghibosadat M; Sunnybrook Research Institute, Toronto, ON, Canada.
Arita Y; Providence Therapeutics Holdings Inc., Calgary, AB, Canada.
Hu Q; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Yue FY; Department of Medicine, University of Toronto, Toronto, ON, Canada.
Banerjee A; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK, Canada.; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK, Canada.; Department of Biology, University of Waterloo, Waterloo, ON, Canada.
Hardy WR; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Mossman K; Department of Medicine, McMaster University, Hamilton, ON, Canada.
Mubareka S; Sunnybrook Research Institute, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, ON, Canada.
Kozak RA; Sunnybrook Research Institute, Toronto, ON, Canada.
Pollanen MS; Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, ON, Canada.
Martin Orozco N; Providence Therapeutics Holdings Inc., Calgary, AB, Canada.
Gingras AC; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health System, Toronto, ON, Canada.
Marcusson EG; Providence Therapeutics Holdings Inc., Calgary, AB, Canada.; Marcusson Consulting, San Francisco, CA, USA.
Ostrowski MA; Department of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada.; Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj9815. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
How is a turbidite actually deposited?
Autorzy :
Ge Z; State Key Laboratory of Petroleum Resources and Prospecting, China University of Petroleum (Beijing), Beijing 102249, China.; College of Geosciences, China University of Petroleum (Beijing), Beijing 102249, China.; Department of Earth Science, University of Bergen, 5007 Bergen, Norway.
Nemec W; Department of Earth Science, University of Bergen, 5007 Bergen, Norway.
Vellinga AJ; School of Ocean and Earth Science, University of Southampton, Southampton SO14 3ZH, UK.
Gawthorpe RL; Department of Earth Science, University of Bergen, 5007 Bergen, Norway.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabl9124. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Inverse design of soft materials via a deep learning-based evolutionary strategy.
Autorzy :
Coli GM; Soft Condensed Matter, Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands.
Boattini E; Soft Condensed Matter, Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands.
Filion L; Soft Condensed Matter, Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands.
Dijkstra M; Soft Condensed Matter, Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj6731. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Targeted gene silencing in the nervous system with CRISPR-Cas13.
Autorzy :
Powell JE; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
Lim CKW; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
Krishnan R; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
McCallister TX; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
Saporito-Magriña C; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
Zeballos MA; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
McPheron GD; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.
Gaj T; Department of Bioengineering, University of Illinois, Urbana, IL 61801, USA.; Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL 61801, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabk2485. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Populations of local direction-selective cells encode global motion patterns generated by self-motion.
Autorzy :
Henning M; Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz 55128, Germany.; Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB) and International Max Planck Research School (IMPRS) for Neurosciences at the University of Göttingen, Göttingen 37077, Germany.
Ramos-Traslosheros G; Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz 55128, Germany.; Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB) and International Max Planck Research School (IMPRS) for Neurosciences at the University of Göttingen, Göttingen 37077, Germany.
Gür B; Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz 55128, Germany.; Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB) and International Max Planck Research School (IMPRS) for Neurosciences at the University of Göttingen, Göttingen 37077, Germany.
Silies M; Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz 55128, Germany.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabi7112. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Peptide framework for screening the effects of amino acids on assembly.
Autorzy :
Hamsici S; Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73069 USA.
White AD; Department of Chemical Engineering, University of Rochester, Rochester, NY 14627, USA.
Acar H; Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73069 USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj0305. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Widespread occurrence of hybrid internal-terminal exons in human transcriptomes.
Autorzy :
Fiszbein A; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Boston University, Boston, MA, USA.
McGurk M; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Calvo-Roitberg E; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Kim G; Department of Biology, Boston University, Boston, MA, USA.
Burge CB; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Pai AA; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabk1752. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Up-regulation of proBDNF/p75 signaling in antibody-secreting cells drives systemic lupus erythematosus.
Autorzy :
Shen WY; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Luo C; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Hurtado PR; Department of Renal Medicine, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Liu XJ; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Luo RY; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Li H; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Hu ZL; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Xu JM; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Coulson EJ; Queensland Brain Institute, The University of Queensland, 4072 Brisbane, Australia.
Zhao M; Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
Zhou XF; School of Pharmacy and Medical Sciences, Division of Health Sciences, University of South Australia, Adelaide, SA 5000, Australia.
Dai RP; Department of Anesthesiology, The Second Xiangya Hospital, Central South University, 139 Ren-Min Central Road, Changsha City, Hunan 410011, China.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj2797. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Biometrics-protected optical communication enabled by deep learning-enhanced triboelectric/photonic synergistic interface.
Autorzy :
Dong B; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.; NUS Graduate School-Integrative Sciences and Engineering Programme (ISEP), National University of Singapore, Singapore, Singapore 119077.
Zhang Z; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.
Shi Q; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.
Wei J; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.
Ma Y; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.
Xiao Z; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.
Lee C; Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore 117583.; Center for Intelligent Sensors and MEMS, National University of Singapore, Singapore, Singapore 117608.; NUS Graduate School-Integrative Sciences and Engineering Programme (ISEP), National University of Singapore, Singapore, Singapore 119077.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabl9874. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Trade-off between sex and growth in diatoms: Molecular mechanisms and demographic implications.
Autorzy :
Annunziata R; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Mele BH; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Marotta P; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Volpe M; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Entrambasaguas L; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Mager S; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Stec K; Stazione Zoologica Anton Dohrn, Napoli, Italy.
d'Alcalà MR; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Sanges R; International School for Advanced Studies (SISSA), Via Bonomea 265, Trieste 34136, Italy.
Finazzi G; Université Grenoble Alpes (UGA), Centre National Recherche Scientifique (CNRS), Commissariat Energie Atomique, Energies Alternatives (CEA), Institut National Recherche Agriculture, Alimentation, Environnement (INRAE), Interdisciplinary Research Institute of Grenoble, IRIG-Laboratoire de Physiologie Cellulaire et Végétale, Grenoble, France.
Iudicone D; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Montresor M; Stazione Zoologica Anton Dohrn, Napoli, Italy.
Ferrante MI; Stazione Zoologica Anton Dohrn, Napoli, Italy.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabj9466. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Complaints about excessive use of police force in women's neighborhoods and subsequent perinatal and cardiovascular health.
Autorzy :
Freedman AA; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, IL, USA.; Institute for Policy Research, Northwestern University, Evanston, IL, USA.
Papachristos AV; Institute for Policy Research, Northwestern University, Evanston, IL, USA.; Department of Sociology, Northwestern University, Evanston, IL, USA.
Smart BP; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, IL, USA.
Keenan-Devlin LS; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, IL, USA.; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.
Khan SS; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Borders A; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, Evanston, IL, USA.; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.; Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Kershaw KN; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Miller GE; Institute for Policy Research, Northwestern University, Evanston, IL, USA.; Department of Psychology, Northwestern University, Evanston, IL, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabl5417. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a.
Autorzy :
Bessa LM; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Guseva S; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Camacho-Zarco AR; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Salvi N; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Maurin D; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Perez LM; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Botova M; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Malki A; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Nanao M; Structural Biology Group, European Synchrotron Radiation Facility, F-38000 Grenoble, France.
Jensen MR; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Ruigrok RWH; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Blackledge M; Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabm4034. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity.
Autorzy :
Ye H; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Feng B; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA.
Wang C; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Saito K; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Yang Y; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Ibrahimi L; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Schaul S; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Patel N; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Saenz L; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Luo P; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Lai P; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Torres V; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Kota M; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Dixit D; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Cai X; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Qu N; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Hyseni I; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Yu K; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Jiang Y; Department of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Tong Q; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Sun Z; Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Arenkiel BR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
He Y; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA.
Xu P; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA.; Department of Physiology and Biophysics, The University of Illinois at Chicago, Chicago, IL 60612, USA.
Xu Y; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabk0185. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Preneoplastic somatic mutations including MYD88 in lymphoplasmacytic lymphoma.
Autorzy :
Rodriguez S; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Celay J; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Goicoechea I; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Jimenez C; Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigación del Cancer (IBMCC-USAL, CSIC), CIBER-ONC, Salamanca, Spain.
Botta C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
Garcia-Barchino MJ; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Garces JJ; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Larrayoz M; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Santos S; Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.
Alignani D; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Vilas-Zornoza A; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Perez C; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Garate S; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Sarvide S; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Lopez A; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Reinhardt HC; Department of Hematology and Stem Cell Transplantation, West German Cancer Center, DKTK Partner Site Essen, Center for Molecular Biotechnology, University Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany.
Carrasco YR; Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB)-CSIC, Madrid, Spain.
Sanchez-Garcia I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Larrayoz MJ; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Calasanz MJ; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Panizo C; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Prosper F; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Lamo-Espinosa JM; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Motta M; Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy.
Tucci A; Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy.
Sacco A; Clinical Research Development and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
Gentile M; Department of Oncohematology, 'Annunziata' Hospital, Cosenza, Italy.
Duarte S; Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.
Vitoria H; Hospital de S. Teotónio, Viseu, Portugal.
Geraldes C; Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.
Paiva A; Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.
Puig N; Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigación del Cancer (IBMCC-USAL, CSIC), CIBER-ONC, Salamanca, Spain.
Garcia-Sanz R; Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigación del Cancer (IBMCC-USAL, CSIC), CIBER-ONC, Salamanca, Spain.
Roccaro AM; Clinical Research Development and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
Fuerte G; Mission Bio, San Francisco, CA, USA.
San Miguel JF; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Martinez-Climent JA; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
Paiva B; Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC, Pamplona, Spain.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabl4644. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
From structure to sequence: Antibody discovery using cryoEM.
Autorzy :
Antanasijevic A; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Bowman CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Kirchdoerfer RN; Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, WI 53706, USA.
Cottrell CA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Upadhyay AA; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, GA 30329, USA.; Yerkes Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Yerkes Nonhuman Primate Genomics Core, Emory University, Atlanta, GA 30329, USA.
Cirelli KM; Vaccine Discovery Division, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Carnathan DG; Yerkes Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Yerkes Nonhuman Primate Genomics Core, Emory University, Atlanta, GA 30329, USA.
Enemuo CA; Yerkes Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Yerkes Nonhuman Primate Genomics Core, Emory University, Atlanta, GA 30329, USA.
Sewall LM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Nogal B; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Zhao F; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; International AIDS Vaccine Initiative-Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA.
Groschel B; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Schief WR; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
Sok D; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; International AIDS Vaccine Initiative-Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA.
Silvestri G; Yerkes Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Yerkes Nonhuman Primate Genomics Core, Emory University, Atlanta, GA 30329, USA.
Crotty S; Vaccine Discovery Division, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Bosinger SE; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, GA 30329, USA.; Yerkes Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Yerkes Nonhuman Primate Genomics Core, Emory University, Atlanta, GA 30329, USA.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabk2039. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A comprehensive long-read isoform analysis platform and sequencing resource for breast cancer.
Autorzy :
Veiga DFT; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Nesta A; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA.
Zhao Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Mays AD; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Huynh R; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Rossi R; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Wu TC; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Palucka K; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
Anczukow O; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA.; Institute for Systems Genomics, University of Connecticut Health Center, Farmington, CT 06030, USA.
Beck CR; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT 06030, USA.; Institute for Systems Genomics, University of Connecticut Health Center, Farmington, CT 06030, USA.
Banchereau J; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032 USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabg6711. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Class I histone deacetylases (HDAC1-3) are histone lysine delactylases.
Autorzy :
Moreno-Yruela C; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Zhang D; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.
Wei W; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.
Bæk M; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Liu W; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.
Gao J; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.
Danková D; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Nielsen AL; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Bolding JE; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Yang L; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.
Jameson ST; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Wong J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.
Olsen CA; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Zhao Y; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.
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Źródło :
Science advances [Sci Adv] 2022 Jan 21; Vol. 8 (3), pp. eabi6696. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article
Czasopismo naukowe

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