JN: "Scientific reports [Sci Rep] NLMUID: 101563288" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells.
Autorzy:: Lv S; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Pan Q; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Lu W; The Fifth Affiliated Hospital of Jinan University (Heyuan Shenhe People's Hospital), Heyuan, 517000, China.
Zhang W; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Wang N; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Huang L; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Li L; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Liu J; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Ma J; Medicine and Health Science College, Guangzhou Huashang College, Guangzhou, People's Republic of China.
Li Z; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Huang Y; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Deng Q; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China. .
Lei X; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Apr 01; Vol. 14 (1), pp. 7654. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Ferroptosis*
Humans ; ErbB Receptors/metabolism ; Apoptosis ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Protein Kinase Inhibitors/pharmacology ; Mutation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Monolayer culture alters EGFR inhibitor response through abrogation of microRNA-mediated feedback regulation.
Autorzy:: Florio A; Biomarker Discovery Laboratory, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA.
Johnson S; Biomarker Discovery Laboratory, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Salvatori R; Biomarker Discovery Laboratory, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Vasmatzis G; Biomarker Discovery Laboratory, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. .; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7303. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/metabolism
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/genetics
Humans ; Erlotinib Hydrochloride/pharmacology ; Erlotinib Hydrochloride/therapeutic use ; Feedback ; ErbB Receptors/metabolism ; Cell Line, Tumor ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Drug Resistance, Neoplasm ; Mutation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: 1,2,3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies.
Autorzy:: Belay Y; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa. .
Muller A; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Mokoena FS; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Adeyinka AS; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Motadi LR; Department of Biochemistry, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Oyebamiji AK; Industrial Chemistry Programme, Bowen University, PMB 284, Iwo, Osun State, Nigeria.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 23; Vol. 14 (1), pp. 6951. Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:: Journal Article
MeSH Terms:: Schiff Bases*/pharmacology
Schiff Bases*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Molecular Docking Simulation ; Triazoles/pharmacology ; Triazoles/chemistry ; Structure-Activity Relationship ; Molecular Structure

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
Autorzy:: Hagi T; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Vangveravong S; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Takchi R; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Gong Q; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Goedegebuure SP; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.
Tiriac H; Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California San Diego, San Diego, CA, USA, San Diego, USA.
Van Tine BA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.; Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Powell MA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Hawkins WG; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA. .; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA. .
Spitzer D; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA. .; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 16; Vol. 14 (1), pp. 6373. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/metabolism
Humans ; Animals ; Mice ; Female ; Apoptosis ; Inhibitor of Apoptosis Proteins/metabolism ; Caspases/metabolism ; Cell Line, Tumor

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Static magnetic field reduces cisplatin resistance via increasing apoptosis pathways and genotoxicity in cancer cell lines.
Autorzy:: Zafari J; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. .
Rastegar-Pouyani N; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Javani Jouni F; Department of Biochemistry and Biophysics, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Najjar N; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azarshin SZ; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jafarzadeh E; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Abdolmaleki P; Department of Biophysics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Hoseini Shirazi F; Pharmaceutical Sciences Research Center and Department of Toxicology and Pharmacology, Faculty of Pharmacy, Shahid Behesthi University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5792. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Ovarian Neoplasms*/pathology
Humans ; Female ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Apoptosis ; DNA Damage ; Magnetic Fields

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Synthesis, anticancer activity, and molecular docking of half-sandwich iron(II) cyclopentadienyl complexes with maleimide and phosphine or phosphite ligands.
Autorzy:: Das S; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland.
Strachanowska M; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Wadowski P; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Juszczak M; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Tokarz P; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Kosińska A; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland.
Palusiak M; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Rybarczyk-Pirek AJ; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Wzgarda-Raj K; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Vasudevan S; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363, Lodz, Poland.
Chworos A; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363, Lodz, Poland.
Woźniak K; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland. .
Rudolf B; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5634. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article
MeSH Terms:: Phosphites*
Coordination Complexes*/chemistry
Carcinoma, Non-Small-Cell Lung*
Lung Neoplasms*
Antineoplastic Agents*/chemistry
Phosphines*
Humans ; Molecular Docking Simulation ; Iron ; Leukocytes, Mononuclear/metabolism ; Spectroscopy, Fourier Transform Infrared ; DNA/metabolism ; Maleimides ; Ferrous Compounds/pharmacology ; Ligands ; Cell Line, Tumor

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B.
Autorzy:: Okahata M; Graduate School of Frontier Biosciences, Osaka University Suita, Osaka, Japan.; Graduate School of Natural Science, Konan University, Kobe, Hyogo, Japan.; Faculty of Science and Engineering, Konan University, Kobe, Hyogo, Japan.; Institute for Integrative Neurobiology, Konan University, Kobe, Hyogo, Japan.
Sawada N; Graduate School of Natural Science, Konan University, Kobe, Hyogo, Japan.
Nakao K; Biomolecular Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
Ohta A; Graduate School of Natural Science, Konan University, Kobe, Hyogo, Japan. o_.; Faculty of Science and Engineering, Konan University, Kobe, Hyogo, Japan. o_.; Institute for Integrative Neurobiology, Konan University, Kobe, Hyogo, Japan. o_.
Kuhara A; Graduate School of Natural Science, Konan University, Kobe, Hyogo, Japan. atsushi_.; Faculty of Science and Engineering, Konan University, Kobe, Hyogo, Japan. atsushi_.; Institute for Integrative Neurobiology, Konan University, Kobe, Hyogo, Japan. atsushi_.; PRIME, AMED, Japan Agency for Medical Research and Development, Tokyo, Japan. atsushi_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 05; Vol. 14 (1), pp. 5401. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:: Journal Article
MeSH Terms:: Camptothecin*/pharmacology
Antineoplastic Agents*
Animals ; Caenorhabditis elegans/genetics ; Fatty Acids, Unsaturated

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Ultra-stable nano-micro bubbles in a biocompatible medium for safe delivery of anti-cancer drugs.
Autorzy:: Bunyatova U; Biomedical Engineering Department, Engineering Facility, Baskent University, Ankara, Turkey. .
Dogan M; Department of Control and Automation Engineering, Faculty of Electrical-Electronics Engineering, Istanbul Technical University, Istanbul, Turkey.
Tekin E; Department of Electronics and Communications Engineering, Faculty of Electrical-Electronics Engineering, Istanbul Technical University, Istanbul, Turkey.
Ferhanoğlu O; Department of Electronics and Communications Engineering, Faculty of Electrical-Electronics Engineering, Istanbul Technical University, Istanbul, Turkey.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5321. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Metal Nanoparticles*
Antineoplastic Agents*
Humans ; Quality of Life ; Silver ; Health Status

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Cytotoxic naphtho- and benzofurans from an endophytic fungus Epicoccum nigrum Ann-B-2 associated with Annona squamosa fruits.
Autorzy:: Elnaggar MS; Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt. .
Fayez S; Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt. shaimaa_.
Anwar A; Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt.
Ebada SS; Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 28; Vol. 14 (1), pp. 4940. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Annona*/chemistry
Benzofurans*/pharmacology
Ascomycota*/chemistry
Antineoplastic Agents*/chemistry
Fruit ; Molecular Structure
SCR Organism:: Epicoccum nigrum

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Cytotoxic and antiviral activities of Jatropha variegata and Jatropha spinosa in relation to their metabolite profile.
Autorzy:: Shari K; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt.
Mohamed OG; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt.; Natural Products Discovery Core, Life Sciences Institute, University of Michigan, Ann Arbor, MI, 48109, USA.
Meselhy KM; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt.
Tripathi A; Natural Products Discovery Core, Life Sciences Institute, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.
Khaleel AE; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt.
Abdel-Sattar E; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt. .
Gedaily RAE; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, Cairo, 11562, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 28; Vol. 14 (1), pp. 4846. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Jatropha*
Influenza A Virus, H1N1 Subtype*
Antineoplastic Agents*
Humans ; Plant Extracts/pharmacology ; Methylene Chloride ; Flavonoids ; Coumarins ; Antiviral Agents/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Neutrophil to lymphocyte ratio may predict efficacy of anti-PD-1 inhibitors in advanced EGFR-mutant non-small cell lung cancer: retrospective cohort study.
Autorzy:: Chen J; Department of Medical Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China.
Zheng Q; Department of Medical Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China.
Zhu S; Department of Medical Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China.
Qiu D; Department of Medical Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China.
Wang J; Department of Radiation Oncology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 20; Vol. 14 (1), pp. 4165. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Antineoplastic Agents*/therapeutic use
Humans ; Retrospective Studies ; Neutrophils ; Immune Checkpoint Inhibitors/therapeutic use ; Prognosis ; Lymphocytes ; ErbB Receptors ; Mutation ; Protein Kinase Inhibitors/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Process optimization for green synthesis of silver nanoparticles using Rubus discolor leaves extract and its biological activities against multi-drug resistant bacteria and cancer cells.
Autorzy:: Ghasemi S; Department of Medicinal Chemistry, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Dabirian S; Department of Pharmaceutical Biotechnology, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Kariminejad F; Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Koohi DE; Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Nemattalab M; Department of Pharmaceutics, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Majidimoghadam S; Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Zamani E; Department of Pharmacology and Toxicology, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Yousefbeyk F; Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4130. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Rubus*
Metal Nanoparticles*/chemistry
Antineoplastic Agents*/chemistry
Neoplasms*
Silver/pharmacology ; Silver/chemistry ; Spectroscopy, Fourier Transform Infrared ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Anti-Bacterial Agents/chemistry ; Bacteria

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: High-throughput screening assay for PARP-HPF1 interaction inhibitors to affect DNA damage repair.
Autorzy:: Dhakar SS; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland.
Galera-Prat A; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland.
Lehtiö L; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 16; Vol. 14 (1), pp. 3875. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Histones*/drug effects
Histones*/metabolism
Poly(ADP-ribose) Polymerase Inhibitors*/chemistry
Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology
DNA Damage ; DNA Repair ; High-Throughput Screening Assays ; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors ; Poly ADP Ribosylation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment.
Autorzy:: Berthenet K; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Aïmontché E; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
El Mrini S; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Brière J; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Pion N; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Iacono I; Department of Translational Research and Innovation, Centre Léon Bérard, 69373, Lyon, France.
Brejon S; Department of Translational Research and Innovation, Centre Léon Bérard, 69373, Lyon, France.
Monier K; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Catez F; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Ichim G; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.; Institut Convergence PLAsCAN, 69373, Lyon Cedex 08, France.
Combaret V; Department of Translational Research and Innovation, Centre Léon Bérard, 69373, Lyon, France.
Mertani HC; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.
Diaz JJ; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France.; Institut Convergence PLAsCAN, 69373, Lyon Cedex 08, France.; DevWeCan Labex Laboratory, 69373, Lyon Cedex 08, France.
Albaret MA; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008, Lyon, France. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 14; Vol. 14 (1), pp. 3768. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroblastoma*/drug therapy
Neuroblastoma*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Child ; Humans ; Bortezomib/pharmacology ; Bortezomib/therapeutic use ; Caspase 3/pharmacology ; Cell Line, Tumor ; Apoptosis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors.
Autorzy:: Noser AA; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt. .
El-Barbary AA; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Salem MM; Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
El Salam HAA; Green Chemistry Department, National Research Centre, Dokki, GizaCairo, 12622, Egypt.
Shahien M; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 12; Vol. 14 (1), pp. 3530. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Oxazepines*/pharmacology
Anti-Infective Agents*/pharmacology
Antineoplastic Agents*/chemistry
Structure-Activity Relationship ; Molecular Docking Simulation ; Hedgehog Proteins ; Quinazolinones/pharmacology ; Cell Proliferation ; Escherichia coli/metabolism ; Staphylococcus aureus/metabolism ; Glucan 1,3-beta-Glucosidase ; Prospective Studies ; Molecular Structure ; Drug Screening Assays, Antitumor

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Immunological characterization of a long-lasting response in a patient with metastatic triple-negative breast cancer treated with PD-1 and LAG-3 blockade.
Autorzy:: Rivoltini L; Unit of Immunotherapy of Human Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Camisaschi C; Unit of Immunotherapy of Human Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Biomarkers Unit, Department of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Fucà G; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Paolini B; Pathology A Unit, Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Vergani B; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Beretta V; Unit of Immunotherapy of Human Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Damian S; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Duca M; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Cresta S; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Magni M; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Leone BE; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Castelli C; Unit of Immunotherapy of Human Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
de Braud F; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.; Oncology and Hemato-Oncology Department, University of Milan, Milan, Italy.
De Santis F; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy.
Di Nicola M; Immunotherapy and Innovative Therapeutics Unit, Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian,1, 20133, Milan, Italy. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3379. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:: Clinical Trial, Phase II; Clinical Trial, Phase I; Journal Article
MeSH Terms:: Triple Negative Breast Neoplasms*/pathology
Antineoplastic Agents*/therapeutic use
Humans ; Programmed Cell Death 1 Receptor/metabolism ; CD8-Positive T-Lymphocytes ; Treatment Outcome ; B7-H1 Antigen

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Label-free visualization and quantification of the drug-type-dependent response of tumor spheroids by dynamic optical coherence tomography.
Autorzy:: Abd El-Sadek I; Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, 305-8573, Japan.; Department of Physics, Faculty of Science, Damietta University, New Damietta City, Damietta, 34517, Egypt.
Morishita R; Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, 305-8573, Japan.
Mori T; Clinical Research and Regional Innovation, Faculty of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
Makita S; Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, 305-8573, Japan.
Mukherjee P; Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, 305-8573, Japan.
Matsusaka S; Clinical Research and Regional Innovation, Faculty of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.
Yasuno Y; Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, 305-8573, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3366. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/diagnostic imaging
Breast Neoplasms*/drug therapy
Humans ; Female ; Tomography, Optical Coherence/methods ; Spheroids, Cellular ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Novel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments.
Autorzy:: Mehany MM; Laboratory Department, Chemistry Unit, Police Hospital, Agouza, Cairo, Egypt.
Hammam OA; Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt.
Selim AA; Labeled Compounds Department, Hot Laboratories Centre, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt. adli_a_.
Sayed GH; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Anwer KE; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2738. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Iodine Radioisotopes*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Animals ; Mice ; MCF-7 Cells ; Caco-2 Cells ; Cell Proliferation ; Pyridines/pharmacology ; Pyridines/chemistry ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Drug Design ; Molecular Docking Simulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Electrochemical and theoretical studies of the interaction between anticancer drug ponatinib and dsDNA.
Autorzy:: Smarzewska S; Department of Inorganic and Analytical Chemistry, University of Lodz, 12 Tamka Str, 91-403, Lodz, Poland.
Ignaczak A; Department of Physical Chemistry, University of Lodz, 163/165 Pomorska Str, 90-236, Lodz, Poland. .
Koszelska K; Department of Inorganic and Analytical Chemistry, University of Lodz, 12 Tamka Str, 91-403, Lodz, Poland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 27; Vol. 14 (1), pp. 2278. Date of Electronic Publication: 2024 Jan 27.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*
Imidazoles*
Pyridazines*
Models, Theoretical ; Guanine ; Acetates ; Electrodes ; Electrochemical Techniques

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Transcriptomic and proteomic analysis of tumor suppressive effects of GZ17-6.02 against mycosis fungoides.
Autorzy:: Bordeaux ZA; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Reddy SV; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Choi J; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Braun G; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
McKeel J; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Lu W; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Yossef SM; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.
Ma EZ; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA.
West CE; Genzada Pharmaceuticals, Hutchinson, USA.; US Dermatology Partners, Wichita, USA.
Kwatra SG; Department of Dermatology, Johns Hopkins University School of Medicine, Cancer Research Building II, Suite 206 1550 Orleans Street, Baltimore, MD, 21231, USA. .; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, USA. .
Kwatra MM; Department of Anesthesiology, Duke University School of Medicine, Durham, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 23; Vol. 14 (1), pp. 1955. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:: Journal Article
MeSH Terms:: Mycosis Fungoides*
Antineoplastic Agents*
Lymphoma, T-Cell, Cutaneous*
Skin Neoplasms*
Humans ; Animals ; Mice ; Phosphatidylinositol 3-Kinases ; Proteomics ; Quality of Life ; Gene Expression Profiling ; Mammals

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Scientific reports [Sci Rep] NLMUID: 101563288"" wg kryterium: JN

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat