GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma.
Autorzy:
Li Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, People's Republic of China. Fan Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, People's Republic of China. Xu J; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center, 1825 Pressler St., Houston, TX, 77030, USA.; Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, 350001, People's Republic of China. Huo L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. ScottAW; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Jin J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Yang B; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center, 1825 Pressler St., Houston, TX, 77030, USA. Shao S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Ma L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Wang Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Yao X; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Pool Pizzi M; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Sewastjanow Da Silva M; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Zhang G; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center, 1825 Pressler St., Houston, TX, 77030, USA. Zhuo L; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center, 1825 Pressler St., Houston, TX, 77030, USA. Cho EJ; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA. Dalby KN; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA. Shanbhag ND; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. Wang Z; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, People's Republic of China. . Li W; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, McGovern Medical School, The University of Texas Health Science Center, 1825 Pressler St., Houston, TX, 77030, USA. . Song S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. . Ajani JA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. .
Symptom-Based Risk Factors for Retinal Tears and Detachments in Suspected Posterior Vitreous Detachment.
Autorzy:
Ahmad MT; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Sein J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Wang J; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. ScottAW; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Ramroop J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Jiramongkolchai K; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Zimmer-Galler IE; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Handa JT; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Arevalo JF; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma.
Autorzy:
Song S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. . Xu Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, P. R. China. Huo L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Zhao S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Wang R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Li Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, P. R. China. ScottAW; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Pizzi MP; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Wang Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Fan Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Harada K; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Jin J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Ma L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Yao X; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Shanbhag ND; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. Gan Q; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Roy-Chowdhuri S; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Badgwell BD; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Wang Z; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, 110001, P. R. China. Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Ajani JA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. .
LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma.
Autorzy:
Li Y; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang 110001, China. Song S; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Pizzi MP; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Han G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ScottAW; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Jin J; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Xu Y; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang 110001, China. Wang Y; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Huo L; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Ma L; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. Vellano C; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Luo X; Ionis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA. MacLeod R; Ionis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA. Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Wang Z; Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang 110001, China. Ajani JA; Department of Gastrointestinal Medical Oncology, Unit 0426, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
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Źródło:
Cancers [Cancers (Basel)] 2020 Oct 15; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 15.
Interocular asymmetry of foveal avascular zone morphology and parafoveal capillary density in sickle cell retinopathy.
Autorzy:
Zhou DB; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America.; Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. ScottAW; Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America. Linz MO; Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America. Han IC; Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Department of Ophthalmology and Visual Sciences, Institute for Vision Research, University of Iowa, Iowa City, Iowa, United States of America. Castanos MV; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America. Lynch G; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America.; Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. Andrade Romo JS; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America. Linderman RE; Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America. Carroll J; Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.; Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America. Rosen RB; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America.; Icahn School of Medicine at Mount Sinai, New York, New York, United States of America. Chui TY; Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States of America.; Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Jun 10; Vol. 15 (6), pp. e0234151. Date of Electronic Publication: 2020 Jun 10 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue.
Autorzy:
Jin J; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Xu Y; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Huo L; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Ma L; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. ScottAW; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Pizzi MP; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Li Y; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Wang Y; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Yao X; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Song S; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America. Ajani JA; The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Houston, TX, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Feb 13; Vol. 15 (2), pp. e0228910. Date of Electronic Publication: 2020 Feb 13 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Visual function quality of life measure changes upon conversion to neovascular age-related macular degeneration in second eyes.
Autorzy:
Paulus YM; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.; Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA. Jefferys JL; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA. Hawkins BS; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA. ScottAW; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA. .; 600 North Wolfe Street, Maumenee #719, Baltimore, MD, 21287-92272, USA. .
Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8 gene expression and restores enterocyte migration in lipopolysaccharide-induced septic mice.
Autorzy:
Wang X; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Hao L; Department of Chemistry and the International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208, USA. Bu HF; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. ScottAW; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA. Tian K; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.; Department of Gastroenterology, Peking University People's Hospital, Beijing 100044, P. R. China. Liu F; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. De Plaen IG; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Liu Y; Department of Gastroenterology, Peking University People's Hospital, Beijing 100044, P. R. China. Mirkin CA; Department of Chemistry and the International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA. Tan XD; Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
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Źródło:
Scientific reports [Sci Rep] 2016 Aug 19; Vol. 6, pp. 31687. Date of Electronic Publication: 2016 Aug 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Retinal angiomatous proliferation or retinal anastomosis to the lesion.
Autorzy:
ScottAW; Retina Division, Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Bressler SB
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Źródło:
Eye (London, England) [Eye (Lond)] 2010 Mar; Vol. 24 (3), pp. 491-6. Date of Electronic Publication: 2009 Dec 18.
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