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Wyszukujesz frazę ""Scrutton, Nigel S."" wg kryterium: Autor


Tytuł:
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades.
Autorzy:
Mutti FG; School of Chemistry, University of Manchester, Manchester Institute of Biotechnology, Manchester M1 7DN, UK. Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK. .
Knaus T; Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK.
Scrutton NS; Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, UK.
Breuer M; BASF SE, White Biotechnology Research, GBW/B-A030, 67056 Ludwigshafen, Germany.
Turner NJ; School of Chemistry, University of Manchester, Manchester Institute of Biotechnology, Manchester M1 7DN, UK. .
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Źródło:
Science (New York, N.Y.) [Science] 2015 Sep 25; Vol. 349 (6255), pp. 1525-9.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biocatalysis*
Alcohol Dehydrogenase/*chemistry
Alcohols/*chemistry
Amines/*chemical synthesis
Oxidoreductases Acting on CH-NH Group Donors/*chemistry
Alcohol Dehydrogenase/genetics ; Amination ; Bacillus/enzymology ; Bacillus/genetics ; Genetic Engineering ; Hydrogen/chemistry ; Lactobacillus/enzymology ; Lactobacillus/genetics ; Oxidoreductases Acting on CH-NH Group Donors/genetics
Czasopismo naukowe
Tytuł:
New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.
Autorzy:
Payne KA; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
White MD; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Fisher K; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Khara B; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Bailey SS; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Parker D; Innovation/Biodomain, Shell International Exploration and Production, Westhollow Technology Center, 3333 Highway 6 South, Houston, Texas 77082-3101, USA.
Rattray NJ; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Trivedi DK; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Goodacre R; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Beveridge R; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Barran P; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Rigby SE; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Scrutton NS; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Hay S; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
Leys D; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
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Źródło:
Nature [Nature] 2015 Jun 25; Vol. 522 (7557), pp. 497-501. Date of Electronic Publication: 2015 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biocatalysis*
Cycloaddition Reaction*
Carboxy-Lyases/*metabolism
Alkenes/chemistry ; Alkenes/metabolism ; Aspergillus niger/enzymology ; Aspergillus niger/genetics ; Carboxy-Lyases/chemistry ; Carboxy-Lyases/genetics ; Crystallography, X-Ray ; Decarboxylation ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Flavins/biosynthesis ; Flavins/chemistry ; Flavins/metabolism ; Isomerism ; Ligands ; Models, Molecular ; Ubiquinone/biosynthesis
Czasopismo naukowe
Tytuł:
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis.
Autorzy:
White MD; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Payne KA; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Fisher K; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Marshall SA; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Parker D; Innovation/Biodomain, Shell International Exploration and Production, Westhollow Technology Center, 3333 Highway 6 South, Houston, Texas 77082-3101, USA.
Rattray NJ; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Trivedi DK; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Goodacre R; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Rigby SE; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Scrutton NS; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Hay S; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
Leys D; Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, UK.
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Źródło:
Nature [Nature] 2015 Jun 25; Vol. 522 (7557), pp. 502-6. Date of Electronic Publication: 2015 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biocatalysis*
Carboxy-Lyases/*metabolism
Dimethylallyltranstransferase/*metabolism
Flavins/*metabolism
Pseudomonas aeruginosa/*enzymology
Pseudomonas aeruginosa/*metabolism
Ubiquinone/*biosynthesis
Alkyl and Aryl Transferases/chemistry ; Alkyl and Aryl Transferases/metabolism ; Aspergillus niger/enzymology ; Aspergillus niger/genetics ; Carboxy-Lyases/chemistry ; Carboxy-Lyases/genetics ; Catalytic Domain ; Crystallography, X-Ray ; Cycloaddition Reaction ; Decarboxylation ; Dimethylallyltranstransferase/chemistry ; Dimethylallyltranstransferase/genetics ; Electron Transport ; Flavin Mononucleotide/metabolism ; Flavins/biosynthesis ; Flavins/chemistry ; Models, Molecular ; Pseudomonas aeruginosa/genetics
Czasopismo naukowe
Tytuł:
Relating localized protein motions to the reaction coordinate in coenzyme B₁₂-dependent enzymes.
Autorzy:
Jones AR; Manchester Institute of Biotechnology and Faculty of Life Sciences, The University of Manchester, Manchester, UK. />Levy C
Hay S
Scrutton NS
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Źródło:
The FEBS journal [FEBS J] 2013 Jul; Vol. 280 (13), pp. 2997-3008. Date of Electronic Publication: 2013 Mar 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Biocatalysis*
Models, Molecular*
Cobamides/*metabolism
Animals ; Biomedical Research/trends ; Biotechnology/trends ; Cobamides/chemistry ; Humans ; Molecular Conformation ; Molecular Dynamics Simulation ; Protein Binding ; Protein Engineering/trends
Czasopismo naukowe
Tytuł:
Special issue: Catalytic mechanisms by biological systems--introduction.
Autorzy:
Fraaije MW; Molecular Enzymology Group, University of Groningen, Groningen, The Netherlands.
Scrutton NS
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Źródło:
The FEBS journal [FEBS J] 2013 Jul; Vol. 280 (13), pp. 2947. Date of Electronic Publication: 2013 Jun 03.
Typ publikacji:
Introductory Journal Article
MeSH Terms:
Biocatalysis*
Models, Biological*
Animals ; Biomedical Research/trends ; Humans ; Protein Engineering/trends ; Systems Biology/trends
Czasopismo naukowe
Tytuł:
Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase.
Autorzy:
Heyes, Derren J.
Hardman, Samantha J. O.
Hedison, Tobias M.
Hoeven, Robin
Scrutton, Nigel S.
Greetham, Greg M.
Towrie, Michael
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Temat:
PROTOCHLOROPHYLLIDE reductase
BIOCATALYSIS
PHOTOCHEMICAL research
INTRAMOLECULAR charge transfer
HYDROGEN bonding interactions
ELECTRON density
Źródło:
Angewandte Chemie International Edition; Jan2015, Vol. 54 Issue 5, p1512-1515, 4p
Czasopismo naukowe

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