Temat: "Senescence" - OpacWWW

Skocz do pozycji: 41.

Tytuł:: Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Autorzy:: Shrestha N; HCW Biologics Inc., Miramar, Florida, USA.
Chaturvedi P; HCW Biologics Inc., Miramar, Florida, USA.
Zhu X; HCW Biologics Inc., Miramar, Florida, USA.
Dee MJ; HCW Biologics Inc., Miramar, Florida, USA.
George V; HCW Biologics Inc., Miramar, Florida, USA.
Janney C; HCW Biologics Inc., Miramar, Florida, USA.
Egan JO; HCW Biologics Inc., Miramar, Florida, USA.
Liu B; HCW Biologics Inc., Miramar, Florida, USA.
Foster M; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Marsala L; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Wong P; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Cubitt CC; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Foltz JA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Tran J; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Schappe T; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Hsiao K; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Leclerc GM; HCW Biologics Inc., Miramar, Florida, USA.
You L; HCW Biologics Inc., Miramar, Florida, USA.
Echeverri C; HCW Biologics Inc., Miramar, Florida, USA.
Spanoudis C; HCW Biologics Inc., Miramar, Florida, USA.
Carvalho A; HCW Biologics Inc., Miramar, Florida, USA.
Kanakaraj L; HCW Biologics Inc., Miramar, Florida, USA.
Gilkes C; HCW Biologics Inc., Miramar, Florida, USA.
Encalada N; HCW Biologics Inc., Miramar, Florida, USA.
Kong L; HCW Biologics Inc., Miramar, Florida, USA.
Wang M; HCW Biologics Inc., Miramar, Florida, USA.
Fang B; HCW Biologics Inc., Miramar, Florida, USA.
Wang Z; HCW Biologics Inc., Miramar, Florida, USA.
Jiao JA; HCW Biologics Inc., Miramar, Florida, USA.
Muniz GJ; HCW Biologics Inc., Miramar, Florida, USA.
Jeng EK; HCW Biologics Inc., Miramar, Florida, USA.
Valdivieso N; HCW Biologics Inc., Miramar, Florida, USA.
Li L; HCW Biologics Inc., Miramar, Florida, USA.
Deth R; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Berrien-Elliott MM; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Fehniger TA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Rhode PR; HCW Biologics Inc., Miramar, Florida, USA.
Wong HC; HCW Biologics Inc., Miramar, Florida, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 May; Vol. 22 (5), pp. e13806. Date of Electronic Publication: 2023 Mar 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Cellular Senescence*/genetics
Mice ; Animals ; Aging ; Inflammation ; Immunotherapy ; Phenotype

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Skocz do pozycji: 42.

Tytuł:: Altered Mitochondrial Function and Accelerated Aging Phenotype in Neural Stem Cells Derived from Dnm1l Knockout Embryonic Stem Cells.
Autorzy:: Na SB; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Seo BJ; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Hong TK; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Oh SY; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Hong YJ; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Song JH; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Uhm SJ; Department of Animal Science, Sangji University, Wonju 26339, Republic of Korea.
Hong K; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Do JT; Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 19; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:: Journal Article
MeSH Terms:: Mitochondria*/genetics
Cellular Senescence*
Nestin ; Embryonic Stem Cells

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Skocz do pozycji: 43.

Tytuł:: New Possibilities for Evaluating the Development of Age-Related Pathologies Using the Dynamical Network Biomarkers Theory.
Autorzy:: Akagi K; Research Center for Pre-Disease Science, University of Toyama, Toyama 930-8555, Japan.
Koizumi K; Research Center for Pre-Disease Science, University of Toyama, Toyama 930-8555, Japan.; Division of Presymptomatic Disease, Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan.
Kadowaki M; Research Center for Pre-Disease Science, University of Toyama, Toyama 930-8555, Japan.
Kitajima I; Research Center for Pre-Disease Science, University of Toyama, Toyama 930-8555, Japan.
Saito S; Research Center for Pre-Disease Science, University of Toyama, Toyama 930-8555, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Sep 17; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 17.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Healthy Aging*
Biomarkers ; Computational Biology

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Skocz do pozycji: 44.

Tytuł:: Simulation-based Reconstructed Diffusion unveils the effect of aging on protein diffusion in Escherichia coli.
Autorzy:: Mantovanelli L; Department of Biochemistry, University of Groningen, Groningen, the Netherlands.
Linnik DS; Department of Biochemistry, University of Groningen, Groningen, the Netherlands.
Punter M; Department of Biochemistry, University of Groningen, Groningen, the Netherlands.
Kojakhmetov HJ; Dynamical Systems, Geometry and Mathematical Physics Group, University of Groningen, Groningen, the Netherlands.
Śmigiel WM; Department of Biochemistry, University of Groningen, Groningen, the Netherlands.
Poolman B; Department of Biochemistry, University of Groningen, Groningen, the Netherlands.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2023 Sep 11; Vol. 19 (9), pp. e1011093. Date of Electronic Publication: 2023 Sep 11 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Escherichia coli*
Cellular Senescence*
Cell Shape ; Computer Simulation

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Skocz do pozycji: 45.

Tytuł:: Lifelong restructuring of 3D genome architecture in cerebellar granule cells.
Autorzy:: Tan L; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Shi J; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
Moghadami S; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.
Parasar B; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Wright CP; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Seo Y; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Vallejo K; Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Cobos I; Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Duncan L; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Chen R; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Sep 08; Vol. 381 (6662), pp. 1112-1119. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:: Journal Article
MeSH Terms:: Cerebellum*/cytology
Cerebellum*/growth & development
Neurons*/metabolism
Genome*
Chromatin Assembly and Disassembly*
Cellular Senescence*
Animals ; Humans ; Mice ; Imaging, Three-Dimensional ; Single-Cell Analysis ; Atlases as Topic

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Skocz do pozycji: 46.

Tytuł:: Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice.
Autorzy:: Doshida Y; Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan.
Hashimoto S; Department of Molecular Pathophysiology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, 641-8509, Japan.
Iwabuchi S; Department of Molecular Pathophysiology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, 641-8509, Japan.
Takino Y; Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Ishiwata T; Aging and Carcinogenesis, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.
Aigaki T; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan.
Ishigami A; Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan. .; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 30; Vol. 13 (1), pp. 14186. Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Liver*
Cellular Senescence*/genetics
Mice ; Rats ; Animals ; In Situ Hybridization, Fluorescence ; RNA, Messenger/genetics ; Sequence Analysis, RNA

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Skocz do pozycji: 47.

Tytuł:: Aging impairs the neurovascular interface in the heart.
Autorzy:: Wagner JUG; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
Tombor LS; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
Malacarne PF; Institute for Cardiovascular Physiology, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Kettenhausen LM; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Panthel J; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Kujundzic H; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Manickam N; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
Schmitz K; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Cipca M; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Stilz KA; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Fischer A; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Muhly-Reinholz M; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Abplanalp WT; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
John D; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Mohanta SK; Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität München (LMU), 80336 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.
Weber C; Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität München (LMU), 80336 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands.
Habenicht AJR; Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität München (LMU), 80336 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.
Buchmann GK; Institute for Cardiovascular Physiology, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Angendohr S; Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Amin E; Institute of Neural and Sensory Physiology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Scherschel K; Institute of Neural and Sensory Physiology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.; Division of Cardiology/Angiology/Intensive Care, EVK Düsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, 40217 Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf (CARID), Medical Faculty and University Hospital of Düsseldorf, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Klöcker N; Institute of Neural and Sensory Physiology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Kelm M; Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf (CARID), Medical Faculty and University Hospital of Düsseldorf, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Schüttler D; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.; Department of Medicine I, University Hospital Munich, Ludwig Maximilian University, 81377 Munich, Germany.; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICON), LMU Munich, 80539 Munich, Germany.
Clauss S; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.; Department of Medicine I, University Hospital Munich, Ludwig Maximilian University, 81377 Munich, Germany.; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICON), LMU Munich, 80539 Munich, Germany.
Günther S; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
Boettger T; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
Braun T; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
Bär C; Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, 30625 Hannover, Germany.; REBIRTH-Centre for Translational Regenerative Medicine, Hannover Medical School, 30625 Hannover, Germany.
Pham MD; Department of Medicine, Cardiology, Goethe University Hospital, 60590 Frankfurt, Germany.; Genome Biologics, 60590 Frankfurt am Main, Germany.
Krishnan J; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Department of Medicine, Cardiology, Goethe University Hospital, 60590 Frankfurt, Germany.
Hille S; Department of Internal Medicine III, University Hospital Schleswig-Holstein, University of Kiel, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (partner site Hamburg/Kiel/Lübeck), 24105 Kiel, Germany.
Müller OJ; Department of Internal Medicine III, University Hospital Schleswig-Holstein, University of Kiel, 24105 Kiel, Germany.; German Centre for Cardiovascular Research (partner site Hamburg/Kiel/Lübeck), 24105 Kiel, Germany.
Bozoglu T; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.; Klinik und Poliklinik für Innere Medizin I, University Clinic rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Kupatt C; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), 80802 Munich, Germany.; Klinik und Poliklinik für Innere Medizin I, University Clinic rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Nardini E; Institute of Medical Chemistry, Center for Pathobiochemistry and Genetics, Medical University of Vienna, A-1090 Vienna, Austria.
Osmanagic-Myers S; Institute of Medical Chemistry, Center for Pathobiochemistry and Genetics, Medical University of Vienna, A-1090 Vienna, Austria.
Meyer C; Division of Cardiology/Angiology/Intensive Care, EVK Düsseldorf, cNEP, cardiac Neuro- and Electrophysiology Research Consortium, 40217 Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf (CARID), Medical Faculty and University Hospital of Düsseldorf, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Zeiher AM; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
Brandes RP; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Institute for Cardiovascular Physiology, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Luxán G; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.
Dimmeler S; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhein-Main, 60590 Frankfurt, Germany.; Cardiopulmonary Institute (CPI), 60590 Frankfurt, Germany.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Aug 25; Vol. 381 (6660), pp. 897-906. Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:: Journal Article
MeSH Terms:: Heart*/innervation
MicroRNAs*/genetics
MicroRNAs*/metabolism
Semaphorin-3A*/genetics
Aging*/genetics
Aging*/pathology
Cellular Senescence*/genetics
Myocardium*/pathology
Microvascular Density*
Microcirculation ; Animals ; Mice ; Male ; Mice, Inbred C57BL ; Axons

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Skocz do pozycji: 48.

Tytuł:: A quick and reliable image-based AI algorithm for evaluating cellular senescence of gastric organoids.
Autorzy:: Yang R; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Du Y; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Kwan W; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Yan R; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Shi Q; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Zang L; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Zhu Z; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Zhang J; Institute of Translational Medicine, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 201210, China.
Li C; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Yu Y; Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.; Pokaż więcej
Źródło:: Cancer biology & medicine [Cancer Biol Med] 2023 Jun 30; Vol. 20 (7).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Artificial Intelligence*
Cellular Senescence*
Animals ; Humans ; Aging ; Cell Cycle ; Organoids

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Skocz do pozycji: 49.

Tytuł:: Exploring the Communication of the SASP: Dynamic, Interactive, and Adaptive Effects on the Microenvironment.
Autorzy:: Giroud J; Laboratory of Biochemistry and Cell Biology (URBC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, 5000 Namur, Belgium.; University of Lille, CNRS, Inserm, Pasteur Institute of Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, 59000 Lille, France.
Bouriez I; Laboratory of Biochemistry and Cell Biology (URBC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, 5000 Namur, Belgium.
Paulus H; Laboratory of Biochemistry and Cell Biology (URBC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, 5000 Namur, Belgium.
Pourtier A; University of Lille, CNRS, Inserm, Pasteur Institute of Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, 59000 Lille, France.
Debacq-Chainiaux F; Laboratory of Biochemistry and Cell Biology (URBC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, 5000 Namur, Belgium.
Pluquet O; University of Lille, CNRS, Inserm, Pasteur Institute of Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, 59000 Lille, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 28; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cellular Senescence*/genetics
Cell Communication*
Biomarkers ; Phenotype

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Skocz do pozycji: 50.

Tytuł:: Induction of Senescence by Loss of Gata4 in Cardiac Fibroblasts.
Autorzy:: Zhang Z; Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Shayani G; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Xu Y; Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Kim A; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Hong Y; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Feng H; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Zhu H; Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jun 17; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*/genetics
Cellular Senescence*/physiology
Fibroblasts*/metabolism
GATA4 Transcription Factor*/deficiency
GATA4 Transcription Factor*/genetics
GATA4 Transcription Factor*/metabolism
Myocytes, Cardiac*/metabolism
Animals ; Mice ; Gene Expression Regulation ; Mice, Knockout ; Transcription Factors/metabolism

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Skocz do pozycji: 51.

Tytuł:: Senopathies-Diseases Associated with Cellular Senescence.
Autorzy:: Lushchak O; Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.; Department of Biochemistry and Biotechnology, Precarpathian National University, 76000 Ivano-Frankivsk, Ukraine.; Research and Development University, 76018 Ivano-Frankivsk, Ukraine.
Schosserer M; Institute of Medical Genetics, Center for Pathobiochemistry and Genetics, Medical University of Vienna, 1090 Vienna, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria.
Grillari J; Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria.; Institute of Molecular Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, 1190 Vienna, Austria.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Jun 08; Vol. 13 (6). Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Aging*
Animals ; Humans ; Biomarkers/metabolism ; Lung/metabolism ; Phenotype

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Skocz do pozycji: 52.

Tytuł:: Cellular senescence in skin-related research: Targeted signaling pathways and naturally occurring therapeutic agents.
Autorzy:: Dańczak-Pazdrowska A; Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
Gornowicz-Porowska J; Department and Division of Practical Cosmetology and Skin Diseases Prophylaxis, Poznan University of Medical Sciences, Poznan, Poland.
Polańska A; Department of Dermatology and Venereology, Poznan University of Medical Sciences, Poznan, Poland.
Krajka-Kuźniak V; Department of Pharmaceutical Biochemistry, Poznan University of Medical Sciences, Poznan, Poland.
Stawny M; Department of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Poznan, Poland.
Gostyńska A; Department of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Poznan, Poland.
Rubiś B; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Poznan, Poland.
Nourredine S; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Ashiqueali S; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Schneider A; Faculdade de Nutrição, Universidade Federal de Pelotas, Pelotas, RS, Brazil.
Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Wyles SP; Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Masternak MM; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Jun; Vol. 22 (6), pp. e13845. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Cellular Senescence*/physiology
Skin Aging*
Humans ; Signal Transduction

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Skocz do pozycji: 53.

Tytuł:: Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy.
Autorzy:: Cayo A; Center for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.; Institute for Interdisciplinary Research, Academic Vice Rectory, University of Talca, Talca 3460000, Chile.
Venturini W; Center for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.; Institute for Interdisciplinary Research, Academic Vice Rectory, University of Talca, Talca 3460000, Chile.
Rebolledo-Mira D; Center for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.
Moore-Carrasco R; Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, University of Talca, Talca 3460000, Chile.
Herrada AA; Lymphatic and Inflammation Research Laboratory, Facultad de Ciencias de la Salud, Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Talca 3467987, Chile.
Nova-Lamperti E; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, Universidad de Concepción, Concepción 4070386, Chile.
Valenzuela C; Center for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.
Brown NE; Center for Medical Research, School of Medicine, University of Talca, Talca 3460000, Chile.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 26; Vol. 24 (11). Date of Electronic Publication: 2023 May 26.
Typ publikacji:: Journal Article
MeSH Terms:: Cellular Senescence*
Piperazines*/pharmacology
Humans ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Carcinogenesis ; Autophagy

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Skocz do pozycji: 54.

Tytuł:: A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence.
Autorzy:: Kang T; Buck Institute for Research on Aging, Novato, CA 94945, USA.; Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.
Moore EC; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Kopania EEK; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
King CD; Buck Institute for Research on Aging, Novato, CA 94945, USA.
Schilling B; Buck Institute for Research on Aging, Novato, CA 94945, USA.
Campisi J; Buck Institute for Research on Aging, Novato, CA 94945, USA.
Good JM; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Brem RB; Buck Institute for Research on Aging, Novato, CA 94945, USA.; Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 Jul 05; Vol. 13 (7).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Cellular Senescence*/genetics
DNA Damage*
Animals ; Mice ; Cell Cycle ; Cytokines/metabolism ; Tumor Suppressor Protein p53/genetics ; Upstream Stimulatory Factors/genetics

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Skocz do pozycji: 55.

Tytuł:: Photomodulation alleviates cellular senescence of aging adipose-derived stem cells.
Autorzy:: Zhang T; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
He Y; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Shu X; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Ma X; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Wu J; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Du Z; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Xu J; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Chen N; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
You J; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Liu Y; Department of Reproductive Technology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China.
Li T; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China.; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China.; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China.
Wu J; Department of Pharmacology, School of Pharmacy Drug Discovery Research Center of Southwest Medical University, and Laboratory for Cardiovascular Pharmacology, Southwest Medical University, Luzhou, Sichuan, China. .; Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, China. .; Metabolic Vascular Disease Key Laboratory of Sichuan Province, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology, Luzhou, 646000, Sichuan, China. .; Drug Discovery Research Center, Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2023 Jun 19; Vol. 21 (1), pp. 146. Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:: Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adipose Tissue*/metabolism
Cellular Senescence*/genetics
Animals ; Mice ; Cell Differentiation ; Cell Proliferation ; Stem Cells ; Cells, Cultured

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Skocz do pozycji: 56.

Tytuł:: Cellular Senescence, Inflammation, and Cancer in the Gastrointestinal Tract.
Autorzy:: Choi EL; Graduate Research Education Program (Choi), Mayo Clinic, Rochester, MN 55905, USA.
Taheri N; Department of Physiology and Biomedical Engineering (Taheri, Chandra and Hayashi), Mayo Clinic, Rochester, MN 55905, USA.; Division of Gastroenterology and Hepatology (Taheri and Hayashi), Mayo Clinic, Rochester, MN 55905, USA.
Chandra A; Department of Physiology and Biomedical Engineering (Taheri, Chandra and Hayashi), Mayo Clinic, Rochester, MN 55905, USA.; Robert and Arlene Kogod Center on Aging (Chandra), Mayo Clinic, Rochester, MN 55905, USA.
Hayashi Y; Department of Physiology and Biomedical Engineering (Taheri, Chandra and Hayashi), Mayo Clinic, Rochester, MN 55905, USA.; Division of Gastroenterology and Hepatology (Taheri and Hayashi), Mayo Clinic, Rochester, MN 55905, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 06; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cellular Senescence*
Neoplasms*/metabolism
Humans ; Inflammation ; Gastrointestinal Tract/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 57.

Tytuł:: Involvement of ACACA (acetyl-CoA carboxylase α) in the lung pre-metastatic niche formation in breast cancer by senescence phenotypic conversion in fibroblasts.
Autorzy:: Huang YC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Hou MF; Department of Biomedical Science and Environment Biology, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Tsai YM; Division of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan.; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Pan YC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Tsai PH; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Lin YS; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Chang CY; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan.; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.; Department of Anatomy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Tsai EM; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Hsu YL; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung, 807, Taiwan. .; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. .; Department of Biological Science and Technology, National Pingtung University of Science and Technology, Pingtung, 912, Taiwan. .; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Jun; Vol. 46 (3), pp. 643-660. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:: Journal Article
MeSH Terms:: Acetyl-CoA Carboxylase*/genetics
Acetyl-CoA Carboxylase*/metabolism
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Cellular Senescence*/genetics
Fibroblasts*/metabolism
Fibroblasts*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/secondary
Animals ; Mice ; Down-Regulation ; Lung/metabolism ; Lung/pathology ; Humans

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Skocz do pozycji: 58.

Tytuł:: A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo.
Autorzy:: Morsli S; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
Henriques CM; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
Ellis PS; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
Mortiboys H; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.
Baxendale S; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; School of Biosciences, University of Sheffield, Sheffield, S10 2TH, UK.
Loynes CA; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
Renshaw SA; The Bateson Centre, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
Bellantuono I; Healthy Lifespan Institute, University of Sheffield, Western Bank, Sheffield, S10 2TH, UK.; Department of Oncology and Metabolism, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Jun; Vol. 22 (6), pp. e13835. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Zebrafish*/genetics
Animals ; Aging/genetics ; Green Fluorescent Proteins/genetics ; Mammals ; Senotherapeutics

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Skocz do pozycji: 59.

Tytuł:: Effect of Monocerin, a Fungal Secondary Metabolite, on Endothelial Cells.
Autorzy:: Gomes TC; Development and Innovation Laboratory, Instituto Butantan, Avenida Vital Brasil, 1500, Sao Paulo 05503-900, SP, Brazil.
Conrado R; Development and Innovation Laboratory, Instituto Butantan, Avenida Vital Brasil, 1500, Sao Paulo 05503-900, SP, Brazil.
Oliveira RC; Department of Biochemical and Pharmaceutical Technology, FCF, University of Sao Paulo, Sao Paulo 05508-000, SP, Brazil.
Selari PJRG; Federal Institute of Education, Science and Technology Goiano, Ceres 76300-000, GO, Brazil.
Melo IS; Environmental Microbiology Laboratory, EMBRAPA Meio Ambiente, Jaguariuna 13918-110, SP, Brazil.
Araújo WL; Laboratory of Molecular Biology and Microbial Ecology (LABMEM), Microbiology Department, ICB II, University of Sao Paulo, Sao Paulo 05508-000, SP, Brazil.
Maria DA; Development and Innovation Laboratory, Instituto Butantan, Avenida Vital Brasil, 1500, Sao Paulo 05503-900, SP, Brazil.
De Souza AO; Development and Innovation Laboratory, Instituto Butantan, Avenida Vital Brasil, 1500, Sao Paulo 05503-900, SP, Brazil.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 May 18; Vol. 15 (5). Date of Electronic Publication: 2023 May 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Lactones*/pharmacology
Humans ; Human Umbilical Vein Endothelial Cells ; Cells, Cultured ; Cell Proliferation

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Skocz do pozycji: 60.

Tytuł:: The effect of Dendrobium officinale extract in inhibiting the senescence of H 2 O 2 -induced fibroblasts based on the senescence-associated secretory phenotype.
Autorzy:: Li L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhu L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Chen M; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhao Y; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Jia H; Shanghai Jahwa United Co., Ltd., Shanghai, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1360-1364. Date of Electronic Publication: 2023 Dec 06.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-6*
Dendrobium*
Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence ; Matrix Metalloproteinase 1 ; Hydrogen Peroxide/pharmacology ; Fibroblasts

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