Temat: "Senescence-Associated Secretory Phenotype" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Cell senescence, the senescence-associated secretory phenotype, and cancers.
Autorzy:: Langhi Prata LGP; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2023 Sep 21; Vol. 21 (9), pp. e3002326. Date of Electronic Publication: 2023 Sep 21 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Neoplasms*/genetics
Humans ; Cellular Senescence/genetics ; Cell Differentiation ; Inflammation ; Phenotype

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Skocz do pozycji: 2.

Tytuł:: Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Autorzy:: Shrestha N; HCW Biologics Inc., Miramar, Florida, USA.
Chaturvedi P; HCW Biologics Inc., Miramar, Florida, USA.
Zhu X; HCW Biologics Inc., Miramar, Florida, USA.
Dee MJ; HCW Biologics Inc., Miramar, Florida, USA.
George V; HCW Biologics Inc., Miramar, Florida, USA.
Janney C; HCW Biologics Inc., Miramar, Florida, USA.
Egan JO; HCW Biologics Inc., Miramar, Florida, USA.
Liu B; HCW Biologics Inc., Miramar, Florida, USA.
Foster M; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Marsala L; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Wong P; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Cubitt CC; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Foltz JA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Tran J; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Schappe T; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Hsiao K; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Leclerc GM; HCW Biologics Inc., Miramar, Florida, USA.
You L; HCW Biologics Inc., Miramar, Florida, USA.
Echeverri C; HCW Biologics Inc., Miramar, Florida, USA.
Spanoudis C; HCW Biologics Inc., Miramar, Florida, USA.
Carvalho A; HCW Biologics Inc., Miramar, Florida, USA.
Kanakaraj L; HCW Biologics Inc., Miramar, Florida, USA.
Gilkes C; HCW Biologics Inc., Miramar, Florida, USA.
Encalada N; HCW Biologics Inc., Miramar, Florida, USA.
Kong L; HCW Biologics Inc., Miramar, Florida, USA.
Wang M; HCW Biologics Inc., Miramar, Florida, USA.
Fang B; HCW Biologics Inc., Miramar, Florida, USA.
Wang Z; HCW Biologics Inc., Miramar, Florida, USA.
Jiao JA; HCW Biologics Inc., Miramar, Florida, USA.
Muniz GJ; HCW Biologics Inc., Miramar, Florida, USA.
Jeng EK; HCW Biologics Inc., Miramar, Florida, USA.
Valdivieso N; HCW Biologics Inc., Miramar, Florida, USA.
Li L; HCW Biologics Inc., Miramar, Florida, USA.
Deth R; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Berrien-Elliott MM; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Fehniger TA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Rhode PR; HCW Biologics Inc., Miramar, Florida, USA.
Wong HC; HCW Biologics Inc., Miramar, Florida, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 May; Vol. 22 (5), pp. e13806. Date of Electronic Publication: 2023 Mar 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Cellular Senescence*/genetics
Mice ; Animals ; Aging ; Inflammation ; Immunotherapy ; Phenotype

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Skocz do pozycji: 3.

Tytuł:: The effect of Dendrobium officinale extract in inhibiting the senescence of H 2 O 2 -induced fibroblasts based on the senescence-associated secretory phenotype.
Autorzy:: Li L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhu L; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Chen M; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Zhao Y; Shanghai Jahwa United Co., Ltd., Shanghai, China.
Jia H; Shanghai Jahwa United Co., Ltd., Shanghai, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1360-1364. Date of Electronic Publication: 2023 Dec 06.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-6*
Dendrobium*
Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence ; Matrix Metalloproteinase 1 ; Hydrogen Peroxide/pharmacology ; Fibroblasts

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Skocz do pozycji: 4.

Tytuł:: Persistent epigenetic signals propel a senescence-associated secretory phenotype and trained innate immunity in CD34 hematopoietic stem cells from diabetic patients.
Autorzy:: Vinci MC; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy. .
Costantino S; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich and University of Zürich, Zurich, Switzerland.; University Heart Center, University Hospital Zurich, Zurich, Switzerland.
Damiano G; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Rurali E; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Rinaldi R; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Vigorelli V; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Sforza A; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.
Carulli E; Dipartimento Di Scienze Cliniche E Di Comunità, Università Di Milano, Milan, Italy.; Doctoral Programme in Translational Medicine, Università Di Milano, 20122, Milan, Italy.
Pirola S; Department of Cardiac Surgery, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Mastroiacovo G; Department of Cardiac Surgery, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Raucci A; Unit of Experimental Cardio-Oncology and Cardiovascular Aging, Centro Cardiologico Monzino IRCCS, Milan, Italy.
El-Osta A; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.
Paneni F; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, University Hospital Zurich and University of Zürich, Zurich, Switzerland. .; University Heart Center, University Hospital Zurich, Zurich, Switzerland. .
Pompilio G; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy.; Department of Biomedical, Surgical and Dental Sciences, Università Degli Studi di Milano, Milan, Italy.; Pokaż więcej
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Mar 29; Vol. 23 (1), pp. 107. Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:: Journal Article
MeSH Terms:: Trained Immunity*
Diabetes Mellitus, Type 2*/metabolism
Humans ; Senescence-Associated Secretory Phenotype ; Hematopoietic Stem Cells/metabolism ; Antigens, CD34/metabolism ; Epigenesis, Genetic ; Histone-Lysine N-Methyltransferase/genetics ; Histone-Lysine N-Methyltransferase/metabolism

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Skocz do pozycji: 5.

Tytuł:: Aging microenvironment and antitumor immunity for geriatric oncology: the landscape and future implications.
Autorzy:: Zhao B; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Departments of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100032, China.
Wu B; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Feng N; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Zhang X; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Zhang X; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.; Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Wei Y; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Zhang W; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, 1 Minde Road, Nanchang, 330006, China. .; Pokaż więcej
Źródło:: Journal of hematology & oncology [J Hematol Oncol] 2023 Mar 21; Vol. 16 (1), pp. 28. Date of Electronic Publication: 2023 Mar 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Neoplasms*/pathology
Tumor Microenvironment*
Immunotherapy*
Senescence-Associated Secretory Phenotype*
Humans ; Cellular Senescence ; Cytokines/metabolism ; Aging

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Skocz do pozycji: 6.

Tytuł:: The variant senescence-associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia-inducible factor-1α.
Autorzy:: Wu SK; Department of Cell Biology, Harvard Medical School, Massachusetts, Boston, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Massachusetts, Boston, USA.
Ariffin J; Department of Surgery, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts, Boston, USA.
Tay SC; Mechanobiology Institute, National University of Singapore, Singapore.
Picone R; Department of Cell Biology, Harvard Medical School, Massachusetts, Boston, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Massachusetts, Boston, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Mar; Vol. 22 (3), pp. e13766. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Neoplasms*/pathology
Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Cellular Senescence/genetics ; Centrosome/metabolism ; Centrosome/pathology ; Carcinogenesis ; Phenotype ; NF-kappa B/metabolism

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Skocz do pozycji: 7.

Tytuł:: Long-Term Cultured Human Glioblastoma Multiforme Cells Demonstrate Increased Radiosensitivity and Senescence-Associated Secretory Phenotype in Response to Irradiation.
Autorzy:: Alhaddad L; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; Department of Environmental Sciences, Faculty of Sciences, Damascus University, Damascus P.O. Box 30621, Syria.
Nofal Z; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.
Pustovalova M; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.
Osipov AN; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.; N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russia.
Leonov S; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; Institute of Cell Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Glioblastoma*/metabolism
Humans ; Cellular Senescence ; Cell Line ; Cells, Cultured ; Radiation Tolerance ; Phenotype

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Skocz do pozycji: 8.

Tytuł:: Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy.
Autorzy:: Tarallo D; Departamento de Bioquímica, Facultad de Medicina, and Centro de Investigaciones Biomédicas (CEINBIO), Universidad de la República, Montevideo, Uruguay.
Martínez J; Departamento de Bioquímica, Facultad de Medicina, and Centro de Investigaciones Biomédicas (CEINBIO), Universidad de la República, Montevideo, Uruguay.
Leyva A; Institut Pasteur de Montevideo and Instituto de Investigaciones Biológicas Clemente Estable (IIBCE), Montevideo, Uruguay.
Mónaco A; Departamento de Desarrollo Biotecnológico, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Perroni C; Area Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
Tassano M; Area Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
Gambini JP; Centro Uruguayo de Imagenología Molecular (CUDIM) and Centro de Medicina Nuclear (CMN), Hospital de Clínicas Dr. Manuel Quintela, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Cappetta M; Departamento de Genética, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Durán R; Institut Pasteur de Montevideo and Instituto de Investigaciones Biológicas Clemente Estable (IIBCE), Montevideo, Uruguay.
Moreno M; Departamento de Desarrollo Biotecnológico, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay. .
Quijano C; Departamento de Bioquímica, Facultad de Medicina, and Centro de Investigaciones Biomédicas (CEINBIO), Universidad de la República, Montevideo, Uruguay. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 09; Vol. 14 (1), pp. 909. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:: Journal Article
MeSH Terms:: Melanoma*/drug therapy
Melanoma*/genetics
Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence/genetics ; Mitochondria ; Phenotype ; Tumor Microenvironment

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Skocz do pozycji: 9.

Tytuł:: Senescent cells at the crossroads of aging, disease, and tissue homeostasis.
Autorzy:: Kuehnemann C; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA.
Wiley CD; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e13988. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Aging*/physiology
Cellular Senescence*/physiology
Humans ; Animals ; Mice ; Disease Models, Animal ; Senescence-Associated Secretory Phenotype ; Homeostasis

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Skocz do pozycji: 10.

Tytuł:: Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment.
Autorzy:: Petrocelli JJ; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
McKenzie AI; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
de Hart NMMP; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.
Reidy PT; Department of Kinesiology, Nutrition, and Health, Miami University, Oxford, Ohio, USA.
Mahmassani ZS; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.
Keeble AR; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.
Kaput KL; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Wahl MP; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Rondina MT; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Marcus RL; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
Welt CK; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Holland WL; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.
Funai K; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.
Fry CS; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, USA.
Drummond MJ; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA.; Molecular Medicine Program, University of Utah, Salt Lake City, Utah, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Nov; Vol. 22 (11), pp. e13936. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:: Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Male ; Female ; Humans ; Senescence-Associated Secretory Phenotype ; Cellular Senescence/genetics ; Muscle, Skeletal ; Inflammation ; Walking ; Collagen ; Fibrosis

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Skocz do pozycji: 11.

Tytuł:: Senescent Cells: Dual Implications on the Retinal Vascular System.
Autorzy:: Habibi-Kavashkohie MR; Department of Biological Sciences, Université du Québec à Montréal (UQAM), Montréal, QC H2L 2C4, Canada.; The Center of Excellence in Research on Orphan Diseases, Courtois Foundation (CERMO-FC), Montreal, QC H3G 1E8, Canada.
Scorza T; Department of Biological Sciences, Université du Québec à Montréal (UQAM), Montréal, QC H2L 2C4, Canada.; The Center of Excellence in Research on Orphan Diseases, Courtois Foundation (CERMO-FC), Montreal, QC H3G 1E8, Canada.
Oubaha M; Department of Biological Sciences, Université du Québec à Montréal (UQAM), Montréal, QC H2L 2C4, Canada.; The Center of Excellence in Research on Orphan Diseases, Courtois Foundation (CERMO-FC), Montreal, QC H3G 1E8, Canada.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Sep 23; Vol. 12 (19). Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Aging*/pathology
Cellular Senescence*
Humans ; Retina ; Retinal Vessels ; Senescence-Associated Secretory Phenotype

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Skocz do pozycji: 12.

Tytuł:: miR-143-3p Promotes Ovarian Granulosa Cell Senescence and Inhibits Estradiol Synthesis by Targeting UBE2E3 and LHCGR.
Autorzy:: Deng J; Department of Pharmacology, Jinan University, Guangzhou 510632, China.
Tang Y; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Li L; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Huang R; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Wang Z; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Ye T; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Xiao Z; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Hu M; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Wei S; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Wang Y; Department of Cell Biology, Jinan University, Guangzhou 510632, China.
Yang Y; Department of Cell Biology, Jinan University, Guangzhou 510632, China.; Guangdong Province Key Laboratory of Bioengineering Medicine, Guangzhou 510632, China.
Huang Y; Department of Pharmacology, Jinan University, Guangzhou 510632, China.; Department of Cell Biology, Jinan University, Guangzhou 510632, China.; Guangdong Province Key Laboratory of Bioengineering Medicine, Guangzhou 510632, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 08; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:: Journal Article
MeSH Terms:: Estradiol*
MicroRNAs*/genetics
Humans ; Female ; Animals ; Mice ; Ovary ; Receptors, G-Protein-Coupled ; Granulosa Cells ; Senescence-Associated Secretory Phenotype

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Skocz do pozycji: 13.

Tytuł:: IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma.
Autorzy:: Homann L; Department of Dermatology, University of Tuebingen, 72076 Tuebingen, Germany.
Rentschler M; Department of Dermatology, University of Tuebingen, 72076 Tuebingen, Germany.; Institute of Physiology I, Department of Vegetative and Clinical Physiology, University of Tuebingen, 72074 Tuebingen, Germany.
Brenner E; Department of Dermatology, University of Tuebingen, 72076 Tuebingen, Germany.
Böhm K; Department of Dermatology, University of Tuebingen, 72076 Tuebingen, Germany.
Röcken M; Department of Dermatology, University of Tuebingen, 72076 Tuebingen, Germany.
Wieder T; Institute of Physiology I, Department of Vegetative and Clinical Physiology, University of Tuebingen, 72074 Tuebingen, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Apr 30; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Melanoma*/pathology
Senescence-Associated Secretory Phenotype*
Interferon-gamma/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
CD8-Positive T-Lymphocytes/metabolism ; Cellular Senescence ; Humans

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Skocz do pozycji: 14.

Tytuł:: Mechanisms and Regulation of Cellular Senescence.
Autorzy:: Roger L; Structure and Instability of Genomes Laboratory, Muséum National d'Histoire Naturelle (MNHN), CNRS-UMR 7196/INSERM U1154, 43 Rue Cuvier, 75005 Paris, France.
Tomas F; Centre de Recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier, CNRS UMR 5237, 1919 Route de Mende, 34293 Montpellier, France.
Gire V; Centre de Recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier, CNRS UMR 5237, 1919 Route de Mende, 34293 Montpellier, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 06; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Aging*
Cellular Senescence*
DNA Damage*
Senescence-Associated Secretory Phenotype*
Inflammation/*pathology
Animals ; Humans ; Inflammation/etiology ; Signal Transduction

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Skocz do pozycji: 15.

Tytuł:: NGAL as a Potential Target in Tumor Microenvironment.
Autorzy:: Crescenzi E; Istituto per l'Endocrinologia e l'Oncologia Sperimentale, CNR, Via S. Pansini, 5-80131 Naples, Italy.
Leonardi A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, 'Federico II' University of Naples, Via S. Pansini, 5-80131 Naples, Italy.
Pacifico F; Istituto per l'Endocrinologia e l'Oncologia Sperimentale, CNR, Via S. Pansini, 5-80131 Naples, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 15; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Signal Transduction*/drug effects
Signal Transduction*/genetics
Tumor Microenvironment*
Lipocalin-2/*metabolism
Neoplasms/*metabolism
Animals ; Antibodies, Monoclonal/therapeutic use ; CRISPR-Cas Systems ; Gene Editing/methods ; Humans ; Lipocalin-2/antagonists & inhibitors ; Lipocalin-2/genetics ; Lipocalin-2/immunology ; Neoplasms/therapy ; RNA, Small Interfering/genetics ; RNAi Therapeutics/methods ; Secretome/metabolism ; Stromal Cells/metabolism

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Skocz do pozycji: 16.

Tytuł:: Angptl2 is a Marker of Cellular Senescence: The Physiological and Pathophysiological Impact of Angptl2-Related Senescence.
Autorzy:: Thorin-Trescases N; Montreal Heart Institute, University of Montreal, Montreal, QC H1T 1C8, Canada.
Labbé P; Montreal Heart Institute, University of Montreal, Montreal, QC H1T 1C8, Canada.; Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada.
Mury P; Montreal Heart Institute, University of Montreal, Montreal, QC H1T 1C8, Canada.; Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada.
Lambert M; Montreal Heart Institute, University of Montreal, Montreal, QC H1T 1C8, Canada.; Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada.
Thorin E; Montreal Heart Institute, University of Montreal, Montreal, QC H1T 1C8, Canada.; Department of Surgery, Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 12; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Aging/*blood
Angiopoietin-Like Protein 2/*blood
Aging/pathology ; Animals ; Biomarkers/blood ; Humans

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Tytuł:: Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence-associated secretory phenotype.
Autorzy:: Wallis R; Blizard Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry London UK.
Josipovic N; Institute of Pathology University Medical Centre Göttingen Göttingen Germany.
Mizen H; Blizard Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry London UK.
Robles-Tenorio A; Blizard Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry London UK.
Tyler EJ; Blizard Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry London UK.
Papantonis A; Institute of Pathology University Medical Centre Göttingen Göttingen Germany.
Bishop CL; Blizard Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry London UK.; Pokaż więcej
Źródło:: Journal of extracellular vesicles [J Extracell Vesicles] 2021 Feb; Vol. 10 (4), pp. e12041. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Senescence-Associated Secretory Phenotype*
Aging/*metabolism
Extracellular Vesicles/*metabolism
Secretome/*metabolism
Cell Line, Tumor ; Cells, Cultured ; Chromatography, Gel ; Exosomes/chemistry ; Exosomes/metabolism ; Extracellular Vesicles/chemistry ; Humans ; Phenotype ; Proteins/analysis ; Proteomics/methods

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Tytuł:: Inflammaging and Immunosenescence as Part of Skin Aging-A Narrative Review.
Autorzy:: Pająk J; Department of Dermatology, Venereology and Allergology, Wrocław Medical University, 50-368 Wrocław, Poland.
Nowicka D; Department of Dermatology, Venereology and Allergology, Wrocław Medical University, 50-368 Wrocław, Poland.
Szepietowski JC; Department of Dermatology, Venereology and Allergology, Wrocław Medical University, 50-368 Wrocław, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 24; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Immunosenescence*
Skin Aging*
Humans ; Inflammation ; Aging ; Senescence-Associated Secretory Phenotype

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Tytuł:: Ceria Nanoparticles Alleviated Osteoarthritis through Attenuating Senescence and Senescence-Associated Secretory Phenotype in Synoviocytes.
Autorzy:: Ren X; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430072, China.
Zhuang H; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430072, China.
Jiang F; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430072, China.
Zhang Y; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430072, China.
Zhou P; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430072, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 06; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Synoviocytes*/metabolism
Osteoarthritis*/metabolism
Cartilage, Articular*/metabolism
Humans ; Senescence-Associated Secretory Phenotype ; Reactive Oxygen Species/metabolism ; Signal Transduction ; NF-kappa B/metabolism ; Cellular Senescence ; Chondrocytes/metabolism

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Tytuł:: SASP-induced macrophage dysfunction may contribute to accelerated senescent fibroblast accumulation in the dermis.
Autorzy:: Ogata Y; Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Nagoya, Japan.
Yamada T; Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Nagoya, Japan.; Department of Applied Cell and Regenerative Medicine, Fujita Health University School of Medicine, Toyoake, Japan.; Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Hasegawa S; Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Nagoya, Japan.; Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.; Nagoya University-MENARD Collaborative Chair, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sanada A; Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Nagoya, Japan.
Iwata Y; Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Arima M; Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Nakata S; Research Laboratories, Nippon Menard Cosmetic Co., Ltd., Nagoya, Japan.
Sugiura K; Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Akamatsu H; Department of Applied Cell and Regenerative Medicine, Fujita Health University School of Medicine, Toyoake, Japan.; Pokaż więcej
Źródło:: Experimental dermatology [Exp Dermatol] 2021 Jan; Vol. 30 (1), pp. 84-91. Date of Electronic Publication: 2020 Dec 20.
Typ publikacji:: Journal Article
MeSH Terms:: Senescence-Associated Secretory Phenotype*
Fibroblasts/*physiology
Macrophages/*physiology
Adult ; Aged ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/genetics ; Apoptosis/drug effects ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Line ; Cell Polarity ; Cell Survival/drug effects ; Coculture Techniques ; Culture Media, Conditioned/pharmacology ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Dermis/cytology ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Gene Expression/drug effects ; Humans ; Immunohistochemistry ; Infliximab/pharmacology ; Male ; Phagocytosis ; RNA/metabolism ; Receptors, CCR7/genetics ; Receptors, Cell Surface/genetics ; Receptors, Lymphocyte Homing/genetics ; S100 Calcium-Binding Protein A4/metabolism ; Tumor Necrosis Factor Inhibitors/pharmacology ; Young Adult

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