- Tytuł:
- The increases in relative mRNA expressions of inflammatory cytokines and chemokines in splenic macrophages from rats exposed to multi-walled carbon nanotubes by whole-body inhalation for 13 weeks.
- Autorzy:
- Źródło:
- Inhalation toxicology [Inhal Toxicol] 2014 Oct; Vol. 26 (12), pp. 750-8.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Cytokines/*agonists
Inflammation/*chemically induced
Inhalation Exposure/*adverse effects
Macrophages/*drug effects
Nanotubes, Carbon/*toxicity
Spleen/*drug effects
Up-Regulation/*drug effects
Aerosols ; Algorithms ; Animals ; Cells, Cultured ; Chemokines/agonists ; Chemokines/antagonists & inhibitors ; Chemokines/genetics ; Chemokines/metabolism ; Cytokines/antagonists & inhibitors ; Cytokines/genetics ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Female ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Nanotubes, Carbon/analysis ; RNA, Messenger/metabolism ; Rats, Inbred F344 ; Spleen/immunology ; Spleen/metabolism ; Spleen/pathology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Tissue Distribution ; Toxicity Tests, Subchronic
Czasopismo naukowe