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Wyszukujesz frazę ""Serotonin Antagonists"" wg kryterium: Temat


Tytuł:
Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys.
Autorzy:
Hori Y; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
Mimura K; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.; Research Center for Medical and Health Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.
Nagai Y; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
Hori Y; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
Kumata K; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology, Chiba, Japan.
Zhang MR; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology, Chiba, Japan.
Suhara T; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
Higuchi M; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
Minamimoto T; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology, Chiba, Japan.
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Źródło:
PLoS biology [PLoS Biol] 2024 Jan 01; Vol. 22 (1), pp. e3002445. Date of Electronic Publication: 2024 Jan 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin*
Serotonin Antagonists*/pharmacology
Brain/metabolism ; Carrier Proteins/metabolism ; Receptor, Serotonin, 5-HT1B ; Macaca ; Animals
Czasopismo naukowe
Tytuł:
Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model.
Autorzy:
Redenšek Trampuž S; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.; Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia.
van Riet S; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
Nordling Å; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
Ingelman-Sundberg M; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 16; Vol. 14 (1), pp. 1396. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/pathology
Liver Neoplasms*/pathology
Animals ; Humans ; Ketanserin/pharmacology ; Serotonin/pharmacology ; Serotonin/metabolism ; Serotonin Antagonists/pharmacology ; Liver/metabolism ; Fibrosis ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Receptors, Serotonin/metabolism
Czasopismo naukowe
Tytuł:
Unique green chromatography method for the determination of serotonin receptor antagonist (Ondansetron hydrochloride) related substances in a liquid formulation, robustness by quality by design-based design of experiments approach.
Autorzy:
Kowtharapu LP; Department of Analytical Development, Shenzhen DEC Pharmaceutical Co., Ltd, Shenzhen, China.; Department of Chemistry, School of Science, GITAM (deemed to be) University, Hyderabad, India.
Katari NK; Department of Chemistry, School of Science, GITAM (deemed to be) University, Hyderabad, India.
Sandoval CA; Department of Analytical Development, Shenzhen DEC Pharmaceutical Co., Ltd, Shenzhen, China.
Muchakayala SK; Department of Analytical Research & Development, Douglas Pharma US Inc., Warminster, Pennsylvania, USA.
Rekulapally VK; Department of Analytical Research & Development, Hikma Pharmaceuticals USA Inc., Columbus, Ohio, USA.
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Źródło:
Journal of separation science [J Sep Sci] 2022 May; Vol. 45 (10), pp. 1711-1726. Date of Electronic Publication: 2022 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Ondansetron*
Serotonin Antagonists*
Chromatography, High Pressure Liquid/methods ; Drug Contamination ; Drug Stability ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Pindolol potentiates the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice.
Autorzy:
Yaman B; Medicine Faculty, Department of Physiology, Gaziantep University, Gaziantep, Turkey.
Bal R; Medicine Faculty, Department of Physiology, Gaziantep University, Gaziantep, Turkey.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2022 Jan; Vol. 132 (1), pp. 23-30. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji:
Journal Article
MeSH Terms:
Antidepressive Agents/*pharmacology
Dorsal Raphe Nucleus/*drug effects
Motor Activity/*drug effects
Pindolol/*pharmacology
Receptor, Serotonin, 5-HT1A/*drug effects
Serotonin Antagonists/*pharmacology
Venlafaxine Hydrochloride/*pharmacology
Animals ; Antidepressive Agents/administration & dosage ; Behavior, Animal/drug effects ; Drug Synergism ; Mice ; Mice, Inbred BALB C ; Pindolol/administration & dosage ; Piperazines/pharmacology ; Serotonin Antagonists/administration & dosage ; Venlafaxine Hydrochloride/administration & dosage
Czasopismo naukowe
Tytuł:
The Phenoxyalkyltriazine Antagonists for 5-HT 6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.
Autorzy:
Sudoł S; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
Cios A; Department of Clinical Pharmacy, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Jastrzębska-Więsek M; Department of Clinical Pharmacy, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Honkisz-Orzechowska E; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
Mordyl B; Department of Pharmacobiology, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Wilczyńska-Zawal N; Department of Clinical Pharmacy, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Satała G; Department of Medicinal Chemistry, Maj Institute of Pharmacology Polish Academy of Sciences, PL 31-343 Kraków, Poland.
Kucwaj-Brysz K; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
Partyka A; Department of Clinical Pharmacy, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Latacz G; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
Olejarz-Maciej A; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
Wesołowska A; Department of Clinical Pharmacy, Medical College, Jagiellonian University, PL 30-688 Kraków, Poland.
Handzlik J; Faculty of Pharmacy, Medical College in Krakow, Jagiellonian University, PL 30-688 Kraków, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 05; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Cognition Disorders/*drug therapy
Dementia/*drug therapy
Receptors, Serotonin/*chemistry
Serotonin Antagonists/*pharmacology
Triazines/*pharmacology
Animals ; Caco-2 Cells ; Humans ; Male ; Molecular Structure ; Rats ; Rats, Wistar ; Receptors, Serotonin/metabolism ; Serotonin Antagonists/chemistry ; Structure-Activity Relationship ; Triazines/chemistry
Czasopismo naukowe
Tytuł:
Agomelatine: A Potential Multitarget Compound for Neurodevelopmental Disorders.
Autorzy:
Savino, Rosa (AUTHOR)
Polito, Anna Nunzia (AUTHOR)
Marsala, Gabriella (AUTHOR)
Ventriglio, Antonio (AUTHOR)
Di Salvatore, Melanie (AUTHOR)
De Stefano, Maria Ida (AUTHOR)
Valenzano, Anna (AUTHOR)
Marinaccio, Luigi (AUTHOR)
Bellomo, Antonello (AUTHOR)
Cibelli, Giuseppe (AUTHOR)
Monda, Marcellino (AUTHOR)
Monda, Vincenzo (AUTHOR)
Messina, Antonietta (AUTHOR)
Polito, Rita (AUTHOR)
Carotenuto, Marco (AUTHOR)
Messina, Giovanni (AUTHOR)
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Źródło:
Brain Sciences (2076-3425). May2023, Vol. 13 Issue 5, p734. 14p.
Czasopismo naukowe
Tytuł:
Ginsenoside Re attenuates 8-OH-DPAT-induced serotonergic behaviors in mice via interactive modulation between PKCδ gene and Nrf2.
Autorzy:
Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Jeong JH; Department of Global Innovative Drugs, College of Medicine, Graduate School of Chung-Ang University, Chung-Ang University, Seoul, Republic of Korea.
Nguyen BT; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Sharma N; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.; Department of Global Innovative Drugs, College of Medicine, Graduate School of Chung-Ang University, Chung-Ang University, Seoul, Republic of Korea.
Tran CNK; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea.
Lee Y; Department of Industrial Plant Science & Technology, Chungbuk National University, Chungju, Republic of Korea.
Byun JK; Korea Society of Forest Environmental Research, Namyangju, Republic of Korea.
Ko SK; Department of Oriental Medical Food and Nutrition, Semyung University, Jecheon, Republic of Korea.
Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2023 Mar; Vol. 46 (2), pp. 281-296. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Ginsenosides*/pharmacology
Mice ; Animals ; 8-Hydroxy-2-(di-n-propylamino)tetralin/pharmacology ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Receptor, Serotonin, 5-HT1A/genetics ; Glutathione ; Glutathione Disulfide ; Serotonin Antagonists ; Ligases
Czasopismo naukowe
Tytuł:
Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders.
Autorzy:
Nirogi R; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Jayarajan P; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Shinde A; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Mohammed AR; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Grandhi VR; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Benade V; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Goyal VK; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Abraham R; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Jasti V; Suven Life Sciences Limited, Serene Chambers, Road-5, Avenue-7, Banjara Hills, Hyderabad 500034, Telangana, India.
Cummings J; Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas, NV 89154, USA.
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Źródło:
Biomolecules [Biomolecules] 2023 Feb 07; Vol. 13 (2). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Serotonin*
Alzheimer Disease*/metabolism
Animals ; Receptors, Serotonin/metabolism ; Serotonin Antagonists/therapeutic use
Czasopismo naukowe
Tytuł:
Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT 6 and D 3 R Affinity in the 1 H -Pyrrolo[3,2- c ]quinoline Series.
Autorzy:
Grychowska K; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Kraków, Poland.
Pietruś W; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Kulawik L; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Kraków, Poland.
Bento O; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS INSERM, 34094 Montpellier, France.
Satała G; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Bantreil X; IBMM, Université de Montpellier, CNRS, ENSCM, 34094 Montpellier, France.; Institut Universitaire de France (IUF), 75005 Paris, France.
Lamaty F; IBMM, Université de Montpellier, CNRS, ENSCM, 34094 Montpellier, France.
Bojarski AJ; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Gołębiowska J; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Nikiforuk A; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Marin P; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS INSERM, 34094 Montpellier, France.
Chaumont-Dubel S; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS INSERM, 34094 Montpellier, France.
Kurczab R; Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Str., 31-324 Kraków, Poland.
Zajdel P; Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Kraków, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 21; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 21.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin*
Quinolines*/chemistry
Structure-Activity Relationship ; Ligands ; Amines ; Receptors, Serotonin/metabolism ; Serotonin Antagonists/chemistry ; Receptors, Dopamine D3
Czasopismo naukowe
Tytuł:
Antagonists of the serotonin receptor 5A target human breast tumor initiating cells.
Autorzy:
Gwynne WD; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Shakeel MS; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Girgis-Gabardo A; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Kim KH; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Ford E; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Dvorkin-Gheva A; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Aarts C; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Isaac M; Drug Discovery Group, The Ontario Institute for Cancer Research, 661 University Ave Suite 510, Toronto, ON, M5G 0A3, Canada.
Al-Awar R; Drug Discovery Group, The Ontario Institute for Cancer Research, 661 University Ave Suite 510, Toronto, ON, M5G 0A3, Canada.
Hassell JA; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada. .
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Źródło:
BMC cancer [BMC Cancer] 2020 Aug 05; Vol. 20 (1), pp. 724. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Biphenyl Compounds/*pharmacology
Breast Neoplasms/*drug therapy
Neoplastic Stem Cells/*drug effects
Receptors, Serotonin/*metabolism
Serotonin Antagonists/*pharmacology
Animals ; Antineoplastic Agents/pharmacology ; Biphenyl Compounds/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Class I Phosphatidylinositol 3-Kinases/drug effects ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Female ; Gene Knockout Techniques ; Guanidines/chemistry ; Guanidines/metabolism ; Guanidines/pharmacology ; Heterografts ; Humans ; Isoquinolines/chemistry ; Isoquinolines/metabolism ; Isoquinolines/pharmacology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplasm Transplantation ; Proteomics ; Proto-Oncogene Proteins c-akt/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Serotonin/genetics ; Serotonin Antagonists/chemistry ; Serotonin Antagonists/metabolism
Czasopismo naukowe
Tytuł:
The Anti-Serotonin Effect of Parthenolide Derivatives and Standardised Extract from the Leaves of Stizolophus balsamita .
Autorzy:
Nawrot J; Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.
Napierała M; Laboratory of Environmental Research, Department of Toxicology, Poznan University of Medicinal Sciences, Dojazd 30, 60-631 Poznan.
Kaczerowska-Pietrzak K; Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.
Florek E; Laboratory of Environmental Research, Department of Toxicology, Poznan University of Medicinal Sciences, Dojazd 30, 60-631 Poznan.
Gornowicz-Porowska J; Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.
Pelant E; Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.
Nowak G; Department of Medicinal and Cosmetic Natural Products, Poznan University of Medicinal Sciences, Mazowiecka 33, 60-623 Poznan, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Nov 15; Vol. 24 (22). Date of Electronic Publication: 2019 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Plant Extracts*/chemistry
Plant Extracts*/pharmacology
Serotonin Antagonists*/chemistry
Serotonin Antagonists*/pharmacology
Sesquiterpenes*/chemistry
Sesquiterpenes*/pharmacology
Asteraceae/*chemistry
Blood Platelets/*metabolism
Plant Leaves/*chemistry
Serotonin/*metabolism
Animals ; Female ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł:
Identification and Pharmacological Characterization of Two Serotonin Type 7 Receptor Isoforms from Mythimna separata .
Autorzy:
Chen W; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
Gao X; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
Wang H; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
Xie G; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
An S; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
Du Y; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Zhao X; Henan International Joint Laboratory of Green Pest Control, College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 30; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin*/pharmacology
Moths*/genetics
Moths*/metabolism
Animals ; Serotonin Antagonists/pharmacology ; Receptors, Serotonin/metabolism ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł:
Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor.
Autorzy:
Hasan A; Department of Plant Medicals, College of Life Sciences, Andong National University, Andong, 36729, Korea.
Yeom HS; Center for Eco-Friendly New Materials, Korea Research Institute of Chemicals Technology, Yuseong, Daejeon, 34114, Korea.
Ryu J; Center for Eco-Friendly New Materials, Korea Research Institute of Chemicals Technology, Yuseong, Daejeon, 34114, Korea.
Bode HB; Department of Biosciences, Molecular Biotechnology, and Buchmann Institute for Molecular Life Sciences (BMLS), Goethe-Universität Frankfurt am Main, Frankfurt, Germany.
Kim Y; Department of Plant Medicals, College of Life Sciences, Andong National University, Andong, 36729, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2019 Dec 30; Vol. 9 (1), pp. 20358. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insect Proteins/*antagonists & inhibitors
Phenethylamines/*pharmacology
Receptors, Serotonin/*metabolism
Serotonin Antagonists/*pharmacology
Amino Acid Sequence ; Animals ; Bacteria/classification ; Bacteria/genetics ; Bacteria/metabolism ; CRISPR-Cas Systems ; Gene Expression ; Hemocytes/metabolism ; Immunity, Cellular ; Larva ; Phagocytosis/genetics ; Phagocytosis/immunology ; Phenethylamines/chemistry ; Phylogeny ; RNA Interference ; Receptors, Serotonin/genetics ; Secondary Metabolism ; Serotonin Antagonists/chemistry
Czasopismo naukowe
Tytuł:
Kinetic analysis of [ F] altanserin bolus injection in the canine brain using PET imaging.
Autorzy:
Pauwelyn G; Laboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium. .
Vlerick L; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Dockx R; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.; Department of Psychiatry and Medical Psychology, Ghent University, Ghent, Belgium.
Verhoeven J; Laboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Dobbeleir A; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.; Department of Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.
Bosmans T; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Peremans K; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Vanhove C; Institute Biomedical Technology - Medisip - Infinity, Ghent University, Ghent, Belgium.
Polis I; Small animal Departments, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
De Vos F; Laboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
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Źródło:
BMC veterinary research [BMC Vet Res] 2019 Nov 21; Vol. 15 (1), pp. 415. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*metabolism
Dogs/*metabolism
Ketanserin/*analogs & derivatives
Positron-Emission Tomography/*veterinary
Serotonin Antagonists/*pharmacokinetics
Animals ; Female ; Fluorine Radioisotopes ; Ketanserin/administration & dosage ; Ketanserin/pharmacokinetics ; Models, Biological ; Serotonin Antagonists/administration & dosage
Czasopismo naukowe
Tytuł:
Lurasidone inhibits NMDA receptor antagonist-induced functional abnormality of thalamocortical glutamatergic transmission via 5-HT 7 receptor blockade.
Autorzy:
Okada M; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Japan.
Fukuyama K; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Japan.
Ueda Y; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Japan.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Oct; Vol. 176 (20), pp. 4002-4018. Date of Electronic Publication: 2019 Sep 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antipsychotic Agents/*pharmacology
Dizocilpine Maleate/*antagonists & inhibitors
Lurasidone Hydrochloride/*pharmacology
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Receptors, Serotonin/*metabolism
Serotonin Antagonists/*pharmacology
Animals ; Antipsychotic Agents/administration & dosage ; Dizocilpine Maleate/pharmacology ; Glutamic Acid/drug effects ; Glutamic Acid/metabolism ; Lurasidone Hydrochloride/administration & dosage ; Male ; Mediodorsal Thalamic Nucleus/drug effects ; Perfusion ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/metabolism ; Serotonin Antagonists/administration & dosage ; Synaptic Transmission/drug effects ; Thalamus/drug effects ; Thalamus/metabolism
Czasopismo naukowe
Tytuł:
Multitargeting the Action of 5-HT 6 Serotonin Receptor Ligands by Additional Modulation of Kinases in the Search for a New Therapy for Alzheimer's Disease: Can It Work from a Molecular Point of View?
Autorzy:
Czarnota-Łydka K; Department of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.; Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Św. Łazarza 15, 31-530 Krakow, Poland.
Kucwaj-Brysz K; Department of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
Pyka P; Department of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
Haberek W; Department of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
Podlewska S; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Medicinal Chemistry, Smętna Street 12, 31-343 Krakow, Poland.
Handzlik J; Department of Technology and Biotechnology of Drugs, Medical College, Jagiellonian University, Medyczna 9, 30-688 Krakow, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 07; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease*/metabolism
Cognition Disorders*/etiology
Animals ; Humans ; Ligands ; Receptors, Serotonin/metabolism ; Serotonin ; Serotonin Antagonists/pharmacology
Czasopismo naukowe
Tytuł:
Therapeutic Effects of Quetiapine and 5-HT 1A Receptor Agonism on Hyperactivity in Dopamine-Deficient Mice.
Autorzy:
Ochiai Y; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.; Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo 183-0042, Japan.
Fujita M; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Hagino Y; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Kobayashi K; Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University, Fukushima 960-1295, Japan.
Okiyama R; Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo 183-0042, Japan.
Takahashi K; Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo 183-0042, Japan.
Ikeda K; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 04; Vol. 23 (13). Date of Electronic Publication: 2022 Jul 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antipsychotic Agents*/pharmacology
Dopamine*/deficiency
Dopamine*/metabolism
Quetiapine Fumarate*/pharmacology
Receptor, Serotonin, 5-HT1A*/metabolism
Serotonin 5-HT1 Receptor Agonists*/pharmacology
Animals ; Mice ; Serotonin/metabolism ; Serotonin Antagonists/pharmacology
Czasopismo naukowe

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