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Tytuł :
KISS1/KISS1R mediates Sertoli cell apoptosis via the PI3K/AKT signalling pathway in a high‑glucose environment.
Autorzy :
Gan DM; Department of Pediatric Endocrinology, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315000, P.R. China.
Zhang PP; Department of Pediatric Endocrinology, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315000, P.R. China.
Zhang JP; Department of Pediatric Endocrinology, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315000, P.R. China.
Ding SX; Department of Pediatric Endocrinology, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315000, P.R. China.
Fang J; Department of Pediatric Endocrinology, Ningbo Women and Children's Hospital, Ningbo, Zhejiang 315000, P.R. China.
Liu Y; Department of Pediatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Signal Transduction*
Diabetes Mellitus, Experimental/*metabolism
Glucose/*metabolism
Kisspeptins/*metabolism
Receptors, Kisspeptin-1/*metabolism
Sertoli Cells/*metabolism
Animals ; Cells, Cultured ; Glucose/toxicity ; Kisspeptins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Kisspeptin-1/genetics ; Sertoli Cells/drug effects
Czasopismo naukowe
Tytuł :
RANKL regulates male reproductive function.
Autorzy :
Blomberg Jensen M; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. .; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA. .
Andreassen CH; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jørgensen A; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Nielsen JE; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Juel Mortensen L; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Boisen IM; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Schwarz P; Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Toppari J; Institute of Biomedicine, Research Centre for Integrated Physiology and Pharmacology, and Centre for Population Health Research, University of Turku, and Department of Pediatrics, Turku University Hospital, Turku, Finland.
Baron R; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Lanske B; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Juul A; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Nature communications [Nat Commun] 2021 Apr 23; Vol. 12 (1), pp. 2450. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fertility/*physiology
RANK Ligand/*metabolism
Semen Analysis/*methods
Sertoli Cells/*metabolism
Spermatozoa/*metabolism
Animals ; Anti-Mullerian Hormone/blood ; Anti-Mullerian Hormone/metabolism ; Denosumab/pharmacology ; Fertility/drug effects ; Humans ; Inhibins/antagonists & inhibitors ; Inhibins/blood ; Inhibins/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Osteoprotegerin/pharmacology ; RANK Ligand/antagonists & inhibitors ; RANK Ligand/genetics ; Semen/drug effects ; Semen/metabolism ; Sertoli Cells/drug effects ; Sperm Count ; Spermatozoa/cytology ; Spermatozoa/drug effects
Czasopismo naukowe
Tytuł :
Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment.
Autorzy :
Guo J; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA; Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Electronic address: .
Sosa E; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Chitiashvili T; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Nie X; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Rojas EJ; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Oliver E; NORDFERTIL Research Laboratory Stockholm, Childhood Cancer Research Unit, Bioclinicum J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Solna 17164, Sweden.
Plath K; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Hotaling JM; Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Stukenborg JB; NORDFERTIL Research Laboratory Stockholm, Childhood Cancer Research Unit, Bioclinicum J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Solna 17164, Sweden.
Clark AT; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: .
Cairns BR; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Electronic address: .
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Corporate Authors :
DonorConnect; DonorConnect, Murray, UT 84107, USA.
Źródło :
Cell stem cell [Cell Stem Cell] 2021 Apr 01; Vol. 28 (4), pp. 764-778.e4. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Sertoli Cells*
Testis*
Adult ; Female ; Humans ; Male ; Pregnancy ; Single-Cell Analysis ; Spermatogonia ; Stem Cells
Czasopismo naukowe
Tytuł :
Targeted disruption of galectin 3 in mice delays the first wave of spermatogenesis and increases germ cell apoptosis.
Autorzy :
Lei T; Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Aulweg 123, 35385, Giessen, Germany.; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Blois SM; Department of Obstetrics and Fetal Medicine, AG Glycoimmunology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20251, Hamburg, Germany.; Experimental and Clinical Research Center, A Cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, The Charité Universitätsmedizin Berlin, Berlin, Germany.
Freitag N; Department of Obstetrics and Fetal Medicine, AG Glycoimmunology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20251, Hamburg, Germany.; Experimental and Clinical Research Center, A Cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, The Charité Universitätsmedizin Berlin, Berlin, Germany.; Division of General Internal and Psychosomatic Medicine, Berlin Institute of Health, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt Universität zu Berlin, Berlin, Germany.
Bergmann M; Institute of Veterinary Anatomy, Histology, and Embryology, Justus-Liebig-University of Giessen, Giessen, Germany.
Bhushan S; Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Aulweg 123, 35385, Giessen, Germany.
Wahle E; Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Aulweg 123, 35385, Giessen, Germany.
Huang AC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen HL; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Hartmann MF; Steroid Research and Mass Spectrometry Unit, Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University of Giessen, Giessen, Germany.
Wudy SA; Steroid Research and Mass Spectrometry Unit, Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University of Giessen, Giessen, Germany.
Liu FT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Meinhardt A; Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Aulweg 123, 35385, Giessen, Germany.
Fijak M; Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Aulweg 123, 35385, Giessen, Germany. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Apr; Vol. 78 (7), pp. 3621-3635. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Spermatogenesis*
Galectin 3/*physiology
Leydig Cells/*pathology
Sertoli Cells/*pathology
Spermatozoa/*pathology
Animals ; Follicle Stimulating Hormone/metabolism ; Leydig Cells/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Sertoli Cells/metabolism ; Spermatozoa/metabolism ; Testosterone/metabolism
Czasopismo naukowe
Tytuł :
Mutations in non-muscle myosin 2A disrupt the actomyosin cytoskeleton in Sertoli cells and cause male infertility.
Autorzy :
Sung DC; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States.
Ahmad M; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States.
Lerma Cervantes CB; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States.
Zhang Y; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States.
Adelstein RS; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States.
Ma X; Laboratory of Molecular Cardiology, Cell and Developmental Biology Center, Bethesda, MD, 20892-1583, United States; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892-1583, United States. Electronic address: .
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Źródło :
Developmental biology [Dev Biol] 2021 Feb; Vol. 470, pp. 49-61. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Actomyosin/*metabolism
Cytoskeleton/*ultrastructure
Infertility, Male/*genetics
Myosin Heavy Chains/*metabolism
Nonmuscle Myosin Type IIA/*metabolism
Sertoli Cells/*physiology
Actins/metabolism ; Actomyosin/chemistry ; Animals ; Blood-Testis Barrier/metabolism ; Cell Shape ; Cytoskeleton/metabolism ; Infertility, Male/pathology ; Infertility, Male/physiopathology ; Male ; Mice ; Microtubules/chemistry ; Microtubules/metabolism ; Microtubules/ultrastructure ; Myosin Heavy Chains/genetics ; Nonmuscle Myosin Type IIA/genetics ; Nonmuscle Myosin Type IIB/genetics ; Nonmuscle Myosin Type IIB/metabolism ; Organ Size ; Permeability ; Point Mutation ; Sertoli Cells/cytology ; Sertoli Cells/ultrastructure ; Testis/pathology ; Tubulin/metabolism
Czasopismo naukowe
Tytuł :
In "Vitro" Lps-Stimulated Sertoli Cells Pre-Loaded With Microparticles: Intracellular Activation Pathways.
Autorzy :
Arato I; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Milardi D; International Scientific Institute 'Paul VI', Rome, Italy.; Division of Endocrinology, Fondazione Policlinico Universitario 'Agostino Gemelli', Rome, Italy.
Giovagnoli S; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
Grande G; 2nd Department of Medicine, 'Ca' Foncello' Regional Hospital, ULSS2 Marca Trevigiana, Treviso, Italy.
Bellucci C; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Lilli C; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Bartoli S; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Corneli S; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche 'Togo Rosati', Perugia, Italy.
Mazzone P; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche 'Togo Rosati', Perugia, Italy.
Calvitti M; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Baroni T; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Calafiore R; Department of Medicine, University of Perugia, Perugia, Italy.; Division of Medical Andrology and Endocrinology of Reproduction, Saint Mary Hospital, Terni, Italy.
Mancuso F; Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Luca G; Department of Experimental Medicine, University of Perugia, Perugia, Italy.; Division of Medical Andrology and Endocrinology of Reproduction, Saint Mary Hospital, Terni, Italy.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2021 Jan 07; Vol. 11, pp. 611932. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Cell-Derived Microparticles/*metabolism
Intracellular Fluid/*metabolism
Lipopolysaccharides/*toxicity
Sertoli Cells/*metabolism
Signal Transduction/*physiology
Animals ; Animals, Newborn ; Intracellular Fluid/drug effects ; Male ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Phosphorylation/physiology ; Sertoli Cells/drug effects ; Signal Transduction/drug effects ; Swine ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Autophagy in Sertoli cell protects against environmental cadmium-induced germ cell apoptosis in mouse testes.
Autorzy :
Zhou GX; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Zhu HL; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Shi XT; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Nan Y; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Liu WB; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Dai LM; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Xiong YW; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Yi SJ; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Cao XL; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Xu DX; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China.
Wang H; Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Feb 01; Vol. 270, pp. 116241. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cadmium*/toxicity
Sertoli Cells*
Animals ; Apoptosis ; Autophagy ; Germ Cells ; Male ; Mice ; Testis
Czasopismo naukowe
Tytuł :
Crosstalk between Androgen-ZIP9 Signaling and Notch Pathway in Rodent Sertoli Cells.
Autorzy :
Kamińska A; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Marek S; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Pardyak L; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.; Center of Experimental and Innovative Medicine, University of Agriculture in Krakow, 30-248 Kraków, Poland.
Brzoskwinia M; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Bilinska B; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Hejmej A; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 05; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Androgens/*metabolism
Cation Transport Proteins/*physiology
Receptors, Notch/*metabolism
Sertoli Cells/*metabolism
Androgens/pharmacology ; Androgens/physiology ; Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cells, Cultured ; Male ; Mice ; Rats ; Receptor Cross-Talk/drug effects ; Receptor Cross-Talk/physiology ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Sertoli Cells/drug effects ; Sertoli Cells/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Transcription Factor HES-1/genetics ; Transcription Factor HES-1/metabolism
Czasopismo naukowe
Tytuł :
Bifenthrin impairs the functions of Leydig and Sertoli cells in mice via mitochondrion-endoplasmic reticulum dysregulation.
Autorzy :
Ham J; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.
You S; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. Electronic address: .
Lim W; Department of Food and Nutrition, Kookmin University, Seoul, 02707, Republic of Korea. Electronic address: .
Song G; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2020 Nov; Vol. 266 (Pt 3), pp. 115174. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Leydig Cells*
Sertoli Cells*
Animals ; Endoplasmic Reticulum ; Male ; Mice ; Mitochondria ; Phosphatidylinositol 3-Kinases ; Pyrethrins ; Testis
Czasopismo naukowe
Tytuł :
miR-130a promotes immature porcine Sertoli cell growth by activating SMAD5 through the TGF-β-PI3K/AKT signaling pathway.
Autorzy :
Luo H; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Chen B; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Weng B; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Tang X; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Chen Y; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Yang A; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Chu D; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Zeng X; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
Ran M; College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha, China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 15164-15179. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Spermatogenesis*
MicroRNAs/*genetics
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Sertoli Cells/*cytology
Smad5 Protein/*metabolism
Transforming Growth Factor beta/*metabolism
Animals ; Cell Proliferation ; Male ; Mice, Inbred ICR ; MicroRNAs/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt/genetics ; Sertoli Cells/metabolism ; Smad5 Protein/genetics ; Swine ; Transforming Growth Factor beta/genetics
Czasopismo naukowe
Tytuł :
Bta-miR-34b inhibits proliferation and promotes apoptosis via the MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells.
Autorzy :
Zhang L; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Ma T; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Tao Q; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Tan W; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Chen H; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Liu W; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Lin P; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Zhou D; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Wang A; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.; Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Jin Y; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
Tang K; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China.
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Źródło :
Journal of animal science [J Anim Sci] 2020 Oct 01; Vol. 98 (10).
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs*/genetics
MicroRNAs*/metabolism
Sertoli Cells*
Animals ; Apoptosis ; Cattle ; Cell Line, Tumor ; Cell Proliferation ; MAP Kinase Signaling System ; Male
Czasopismo naukowe
Tytuł :
Hypothyroidism induced by postnatal PTU (6-n-propyl-2-thiouracil) treatment decreases Sertoli cell number and spermatogenic efficiency in sexually mature pigs.
Autorzy :
Lara NLM; Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Silva VA Jr; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Recife, PE, Brazil.
Chiarini-Garcia H; Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Garcia SK; Department of Zootechny, School of Veterinary at Federal University of Minas Gerais, Brazil.
Debeljuk L; Southern Illinois University, Carbondale, IL, USA.
Hess RA; Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA.
França LR; Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address: .
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Źródło :
General and comparative endocrinology [Gen Comp Endocrinol] 2020 Dec 01; Vol. 299, pp. 113593. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimetabolites/*toxicity
Hypothyroidism/*pathology
Propylthiouracil/*toxicity
Sertoli Cells/*pathology
Spermatogenesis/*drug effects
Spermatozoa/*pathology
Animals ; Animals, Newborn ; Cell Count ; Hypothyroidism/chemically induced ; Leydig Cells/drug effects ; Leydig Cells/pathology ; Male ; Seminiferous Tubules/drug effects ; Seminiferous Tubules/pathology ; Sertoli Cells/drug effects ; Spermatozoa/drug effects ; Swine
Czasopismo naukowe
Tytuł :
Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production.
Autorzy :
Rossi G; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Dufrusine B; Faculty of Biosciences, and Technology for Food Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Lizzi AR; Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Luzi C; Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Piccoli A; Department of Medicine, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Fezza F; Department of Experimental Medicine and Surgery, Tor Vergata University of Rome, 00133 Rome, Italy.
Iorio R; Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
D'Andrea G; Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Dainese E; Faculty of Biosciences, and Technology for Food Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Cecconi S; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Maccarrone M; Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, 67100 L'Aquila, Italy.; European Center for Brain Research, Santa Lucia Foundation IRCCS, 00142 Rome, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 26; Vol. 21 (23). Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Benzhydryl Compounds/*toxicity
Endocannabinoids/*metabolism
Inhibins/*biosynthesis
Phenols/*toxicity
Sertoli Cells/*metabolism
Animals ; Cell Survival/drug effects ; Cells, Cultured ; Gene Expression Regulation/drug effects ; Male ; Mice ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Cannabinoid/genetics ; Receptors, Cannabinoid/metabolism ; Sertoli Cells/drug effects ; Transferrin/metabolism
Czasopismo naukowe
Tytuł :
[D-galactose (D-gal) disrupts barrier function of murine TM4 sertoli cells via activation of p38MAPK signaling pathway].
Autorzy :
Yang Y; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Zhang C; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Zhang Y; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Yang S; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Ye Y; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Wu J; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Yuan D; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.
Zhao H; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China. *Corresponding author, E-mail: .
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Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2020 Nov; Vol. 36 (11), pp. 1002-1008.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*/drug effects
Sertoli Cells*/metabolism
Signal Transduction*/drug effects
Animals ; Enzyme Activation/drug effects ; Galactose/pharmacology ; Male ; Mice ; Occludin/genetics ; Zonula Occludens-1 Protein/genetics
Czasopismo naukowe
Tytuł :
The role of gonadotrophins in gonocyte transformation during minipuberty.
Autorzy :
Burton E; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.; Department of Pediatrics, University of Melbourne, Melbourne, Australia.
Abeydeera SA; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.
Sarila G; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.
Cho HJ; Biological Optical Microscopy Platform, The University of Melbourne, Melbourne, Australia.
Wu S; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Tien MY; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.; Department of Pediatrics, University of Melbourne, Melbourne, Australia.
Hutson J; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia.; Department of Pediatrics, University of Melbourne, Melbourne, Australia.; Department of Urology, The Royal Children's Hospital, Melbourne, Australia.
Li R; Douglas Stephens Surgical Research Group, Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, Australia. .; Department of Pediatrics, University of Melbourne, Melbourne, Australia. .
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Źródło :
Pediatric surgery international [Pediatr Surg Int] 2020 Nov; Vol. 36 (11), pp. 1379-1385. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Germ Cells/*metabolism
Luteinizing Hormone/*physiology
Sertoli Cells/*metabolism
Spermatogenesis/*physiology
Testis/*metabolism
Animals ; Germ Cells/cytology ; Male ; Mice ; Models, Animal ; Sertoli Cells/cytology ; Testis/cytology
Czasopismo naukowe
Tytuł :
Down regulating PHGDH affects the lactate production of sertoli cells in varicocele.
Autorzy :
Guo WB; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Huang ZH; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Yang C; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Lv XY; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Xia H; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Tian H; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Yang JK; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Zhou QZ; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Chen MK; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Xue KY; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Liu CD; Department of Urology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China. .
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Źródło :
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2020 Jul 14; Vol. 18 (1), pp. 70. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Lactic Acid/*metabolism
Phosphoglycerate Dehydrogenase/*genetics
Sertoli Cells/*metabolism
Varicocele/*genetics
Varicocele/*metabolism
Animals ; Cells, Cultured ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Gene Expression Regulation, Enzymologic/drug effects ; Glycolysis/drug effects ; Glycolysis/genetics ; Humans ; Infertility, Male/genetics ; Infertility, Male/metabolism ; Infertility, Male/pathology ; Male ; Phosphoglycerate Dehydrogenase/antagonists & inhibitors ; Phosphoglycerate Dehydrogenase/metabolism ; RNA, Small Interfering/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sertoli Cells/drug effects ; Sertoli Cells/pathology ; Spermatogenesis/drug effects ; Spermatogenesis/genetics ; Testis/drug effects ; Testis/metabolism ; Testis/pathology ; Varicocele/pathology
Czasopismo naukowe
Tytuł :
Effects of nicotine on porcine pre-pupertal sertoli cells: An in vitro study.
Autorzy :
Marinucci L; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy. Electronic address: .
Balloni S; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
Bellucci C; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
Lilli C; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
Stabile AM; Department of Surgery and Biomedical Sciences, Unit of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia 06132, Italy.
Calvitti M; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
Aglietti MC; Department of Medicine, University of Perugia, Perugia 06132, Italy.
Gambelunghe A; Department of Medicine, University of Perugia, Perugia 06132, Italy; Department of Medicine, Section of Occupational Medicine, Respiratory Diseases and Toxicology, University of Perugia, Perugia 06132, Italy.
Muzi G; Department of Medicine, University of Perugia, Perugia 06132, Italy; Department of Medicine, Section of Occupational Medicine, Respiratory Diseases and Toxicology, University of Perugia, Perugia 06132, Italy.
Rende M; Department of Surgery and Biomedical Sciences, Unit of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia 06132, Italy.
Luca G; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy; Division of Medical Andrology and Endocrinology of Reproduction, Saint Mary Hospital, Terni 05100, Italy.
Mancuso F; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
Arato I; Department of Experimental Medicine, University of Perugia, Perugia 06132, Italy.
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Sep; Vol. 67, pp. 104882. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Nicotine/*toxicity
Sertoli Cells/*drug effects
Animals ; Anti-Mullerian Hormone/genetics ; Apoptosis/drug effects ; Aromatase/genetics ; Cell Survival/drug effects ; Cells, Cultured ; Inhibins/genetics ; Integrins/genetics ; Laminin/genetics ; Male ; Mitogen-Activated Protein Kinases/genetics ; Receptors, FSH/genetics ; Sertoli Cells/metabolism ; Sexual Maturation ; Swine
Czasopismo naukowe
Tytuł :
Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2.
Autorzy :
Ma T; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Hou J; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Zhou Y; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Chen Y; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Qiu J; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Wu J; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Ding J; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Han X; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China.; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China.
Li D; Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, Jiangsu, China. .; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, Jiangsu, China. .
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Źródło :
Environmental health : a global access science source [Environ Health] 2020 Aug 01; Vol. 19 (1), pp. 87. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*drug effects
Dibutyl Phthalate/*adverse effects
Nuclear Proteins/*genetics
Phthalic Acids/*adverse effects
Plasticizers/*adverse effects
Sertoli Cells/*drug effects
Animals ; Cell Proliferation/physiology ; Male ; Mice ; Mice, Inbred BALB C ; Nuclear Proteins/metabolism ; Sertoli Cells/physiology ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Effect of Sertoli Cell Transplantation on Reducing Neuroinflammation-Induced Necroptosis and Improving Motor Coordination in the Rat Model of Cerebellar Ataxia Induced by 3-Acetylpyridine.
Autorzy :
Saeidikhoo S; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
Ezi S; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khatmi A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aghajanpour F; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Soltani R; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abdollahifar MA; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jahanian A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aliaghaei A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
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Źródło :
Journal of molecular neuroscience : MN [J Mol Neurosci] 2020 Jul; Vol. 70 (7), pp. 1153-1163. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Movement*
Necroptosis*
Cerebellar Ataxia/*therapy
Sertoli Cells/*transplantation
Stem Cell Transplantation/*methods
Animals ; Cells, Cultured ; Cerebellar Ataxia/etiology ; Glial Cell Line-Derived Neurotrophic Factor/genetics ; Glial Cell Line-Derived Neurotrophic Factor/metabolism ; Male ; PC12 Cells ; Pyridines/toxicity ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Sertoli Cells/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vimentin/genetics ; Vimentin/metabolism
Czasopismo naukowe
Tytuł :
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Autorzy :
Cui L; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China.
Gu Y; Department of Obstetrics, the People's Hospital of Longhua, Shenzhen, 518109, China.
Liu S; College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 10083, China.
Li M; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China.
Ye J; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China.
Zhang F; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China.
Luo X; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China.
Chang WL; Department of Obstetrics, the People's Hospital of Longhua, Shenzhen, 518109, China. .
Gui Y; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, China. .
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Źródło :
Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2020 Jul; Vol. 27 (7), pp. 1443-1454. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood-Testis Barrier/*metabolism
Seminiferous Epithelium/*metabolism
Sertoli Cells/*metabolism
rab1 GTP-Binding Proteins/*drug effects
Animals ; Blood-Testis Barrier/pathology ; Cells, Cultured ; Coculture Techniques ; Infertility, Male/genetics ; Infertility, Male/metabolism ; Infertility, Male/pathology ; Male ; Mice ; Mice, Transgenic ; Seminiferous Epithelium/pathology ; Sertoli Cells/pathology ; Testis/metabolism ; Testis/pathology ; rab1 GTP-Binding Proteins/genetics
Czasopismo naukowe

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