Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic Target.
Autorzy:
Olenginski LT; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. Kasprzak WK; Bioinformatics and Computational Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. Attionu SK; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. ShapiroBA; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. Dayie TK; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
RNA⁻Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.
Autorzy:
Bindewald E; RNA Biology Laboratory, Basic Science Program, Frederick National Laboratory for Cancer Research supported by the National Cancer Institute, Frederick, MD 21702, USA. . Dai L; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. . Kasprzak WK; RNA Biology Laboratory, Basic Science Program, Frederick National Laboratory for Cancer Research supported by the National Cancer Institute, Frederick, MD 21702, USA. . Kim T; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. . Gu S; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. . ShapiroBA; RNA Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. .
Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.
Autorzy:
Belew AT; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2]. Meskauskas A; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2] Department of Biotechnology and Microbiology, Vilnius University, Vilnius, LT 03101, Lithuania [3]. Musalgaonkar S; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA. Advani VM; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA. Sulima SO; 1] Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA [2] VIB Center for the Biology of Disease, KU Leuven, Campus Gasthuisberg, Herestraat 49, bus 602, 3000 Leuven, Belgium. Kasprzak WK; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA. ShapiroBA; Basic Research Laboratory, National Cancer Institute, Frederick, Maryland 21702, USA. Dinman JD; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, USA.
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Źródło:
Nature [Nature] 2014 Aug 21; Vol. 512 (7514), pp. 265-9. Date of Electronic Publication: 2014 Jul 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.
Autorzy:
Tamim S; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America. Vo DT; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America. Uren PJ; Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California, United States of America. Qiao M; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America. Bindewald E; Basic Science Program, SAIC-Frederick, Inc., Center for Cancer Research Nanobiology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America. Kasprzak WK; Basic Science Program, SAIC-Frederick, Inc., Center for Cancer Research Nanobiology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America. ShapiroBA; Center for Cancer Research Nanobiology Program, National Cancer Institute, Frederick, Maryland, California. Nakaya HI; Department of Clinical Analyses and Toxicology, Institute of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil. Burns SC; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America. Araujo PR; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America. Nakano I; Department of Neurological Surgery, James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America. Radek AJ; Epicentre (An Illumina Company), Madison, Wisconsin, United States of America. Kuersten S; Epicentre (An Illumina Company), Madison, Wisconsin, United States of America. Smith AD; Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California, United States of America. Penalva LO; Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America ; Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Jan 22; Vol. 9 (1), pp. e85591. Date of Electronic Publication: 2014 Jan 22 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.
Autorzy:
McFarland AP; Department of Immunology, University of Washington, Seattle, Washington, USA. Horner SM; 1] Department of Immunology, University of Washington, Seattle, Washington, USA. [2]. Jarret A; Department of Immunology, University of Washington, Seattle, Washington, USA. Joslyn RC; Department of Immunology, University of Washington, Seattle, Washington, USA. Bindewald E; Basic Science Program, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA. ShapiroBA; Center for Cancer Research Nanobiology Program, National Cancer Institute, Frederick, Maryland, USA. Delker DA; Divison of Gastroenterology, Hepatology and Nutrition, School of Medicine, University of Utah, Salt Lake City, Utah, USA. Hagedorn CH; 1] Divison of Gastroenterology, Hepatology and Nutrition, School of Medicine, University of Utah, Salt Lake City, Utah, USA. [2]. Carrington M; 1] Cancer and Inflammation Program, Laboratory of Experimental Immunology, Science Applications International Corporation-Frederick, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA. [2] Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, USA. Gale M Jr; Department of Immunology, University of Washington, Seattle, Washington, USA. Savan R; Department of Immunology, University of Washington, Seattle, Washington, USA.
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Źródło:
Nature immunology [Nat Immunol] 2014 Jan; Vol. 15 (1), pp. 72-9. Date of Electronic Publication: 2013 Nov 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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