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    Tytuł:
    Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques.
    Autorzy:
    Bauer A; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Lindemuth E; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Marino FE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Krause R; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Joy J; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Docken SS; Kirby Institute, University of New South Wales, Sydney, Australia.
    Mallick S; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    McCormick K; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Holt C; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, United States of America.
    Georgiev I; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, United States of America.
    Felber B; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, Maryland, United States of America.
    Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
    Veazey R; Department of Pathology and Laboratory Medicine, Tulane School of Medicine, New Orleans, Louisiana, United States of America.
    Davenport MP; Kirby Institute, University of New South Wales, Sydney, Australia.
    Li H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Departments of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Shaw GM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Departments of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Bar KJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2023 Jul 03; Vol. 19 (7), pp. e1011059. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Simian Acquired Immunodeficiency Syndrome*
    Simian Immunodeficiency Virus*
    HIV Infections*
    HIV-1*
    HIV Seropositivity*
    Animals ; Humans ; Macaca mulatta/metabolism ; env Gene Products, Human Immunodeficiency Virus ; Virus Replication/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.
    Autorzy:
    van Schooten J; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    van Haaren MM; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    Li H; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    McCoy LE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; Division of Infection and Immunity, University College London, London, United Kingdom.
    Havenar-Daughton C; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
    Cottrell CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
    Burger JA; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    van der Woude P; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    Helgers LC; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    Tomris I; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
    Labranche CC; Laboratory for AIDS Vaccine Research and Development, Duke University Medical Center, Durham, North Carolina, United States of America.
    Montefiori DC; Laboratory for AIDS Vaccine Research and Development, Duke University Medical Center, Durham, North Carolina, United States of America.
    Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative-Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, California, United States of America.; Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.
    Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative-Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, California, United States of America.; Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America.
    Moore JP; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
    Sanders RW; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
    Crotty S; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
    Shaw GM; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    van Gils MJ; Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 Aug 25; Vol. 17 (8), pp. e1009736. Date of Electronic Publication: 2021 Aug 25 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    AIDS Vaccines/*administration & dosage
    Antibodies, Neutralizing/*immunology
    Epitopes/*immunology
    HIV Infections/*immunology
    HIV-1/*immunology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    env Gene Products, Human Immunodeficiency Virus/*immunology
    AIDS Vaccines/immunology ; Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/immunology ; Antibody Formation ; Antigens, Viral/immunology ; HIV Antibodies/immunology ; HIV Infections/virology ; Humans ; Immunization ; Infant ; Kenya ; Primates ; Protein Multimerization ; Simian Acquired Immunodeficiency Syndrome/prevention & control ; Simian Immunodeficiency Virus/immunology ; Vaccination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
    Autorzy:
    Charles TP; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Burton SL; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Arunachalam PS; Departments of Pathology, and Microbiology and Immunology, Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, California, United States of America.
    Cottrell CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
    Sewall LM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
    Bollimpelli VS; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Gangadhara S; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Dey AK; International AIDS Vaccine Initiative, New York, New York, United States of America.
    Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
    Shaw GM; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Hunter E; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America.
    Amara RR; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, United States of America.
    Pulendran B; Departments of Pathology, and Microbiology and Immunology, Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, California, United States of America.
    van Gils MJ; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
    Derdeyn CA; Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 Feb 08; Vol. 17 (2), pp. e1009257. Date of Electronic Publication: 2021 Feb 08 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Neutralizing/*immunology
    HIV Antibodies/*immunology
    HIV-1/*immunology
    Polysaccharides/*immunology
    Simian Acquired Immunodeficiency Syndrome/*prevention & control
    Simian Immunodeficiency Virus/*immunology
    env Gene Products, Human Immunodeficiency Virus/*immunology
    Animals ; Epitopes/immunology ; Female ; HIV Infections/immunology ; HIV Infections/virology ; Humans ; Immunization ; Macaca mulatta ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/virology ; Vaccination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.
    Autorzy:
    O'Brien SP; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Swanstrom AE; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Pegu A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Ko SY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Immonen TT; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Del Prete GQ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Fennessey CM; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Gorman J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Foulds KE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Schmidt SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Doria-Rose N; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Williamson C; Division of Medical Virology, University of Cape Town, Cape Town, South Africa.; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
    Hatziioannou T; The Rockefeller University, New York, NY, United States of America.
    Bieniasz PD; The Rockefeller University, New York, NY, United States of America.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, United States of America.
    Li H; Department of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
    Shaw GM; Department of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
    Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Koup RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
    Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
    Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2019 Apr 03; Vol. 15 (4), pp. e1007632. Date of Electronic Publication: 2019 Apr 03 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Mutation*
    HIV Infections/*virology
    HIV-1/*genetics
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*genetics
    env Gene Products, Human Immunodeficiency Virus/*metabolism
    Animals ; Gene Expression Regulation, Viral ; Humans ; Macaca mulatta ; Research Design ; Virus Replication ; env Gene Products, Human Immunodeficiency Virus/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee.
    Autorzy:
    Barbian HJ; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Jackson-Jewett R; ChimpHaven, Inc., Keithville, LA, USA.
    Brown CS; ChimpHaven, Inc., Keithville, LA, USA.
    Bibollet-Ruche F; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Learn GH; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Decker T; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Kreider EF; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Li Y; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
    Sharp PM; Institute of Evolutionary Biology, and Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, UK.
    Shaw GM; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Lifson J; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
    Acosta EP; Department of Medicine and Center for AIDS Research, University of Alabama at Birmingham, Birmingham, AL, USA.
    Saag MS; Department of Medicine and Center for AIDS Research, University of Alabama at Birmingham, Birmingham, AL, USA.
    Bar KJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA.
    Hahn BH; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. .; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 409 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA, 19104-6076, USA. .
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    Źródło:
    Retrovirology [Retrovirology] 2017 Jun 02; Vol. 14 (1), pp. 35. Date of Electronic Publication: 2017 Jun 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Anti-Retroviral Agents/*therapeutic use
    Ape Diseases/*drug therapy
    Ape Diseases/*virology
    Pan troglodytes/*virology
    Simian Acquired Immunodeficiency Syndrome/*drug therapy
    Simian Immunodeficiency Virus/*drug effects
    Animals ; Anti-Retroviral Agents/administration & dosage ; Anti-Retroviral Agents/blood ; Antiretroviral Therapy, Highly Active/adverse effects ; CD4 Lymphocyte Count ; Drug Resistance, Viral ; Male ; Mutation ; RNA, Viral/blood ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/genetics ; Simian Immunodeficiency Virus/physiology ; Viral Load/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.
    Autorzy:
    Roberts ER; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Biomedical Graduate Studies in Immunology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.
    Carnathan DG; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Li H; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Shaw GM; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Silvestri G; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Betts MR; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Dec 30; Vol. 12 (12), pp. e1006135. Date of Electronic Publication: 2016 Dec 30 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    CD8-Positive T-Lymphocytes/*immunology
    CD8-Positive T-Lymphocytes/*virology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    Simian Immunodeficiency Virus/*immunology
    Animals ; Fluorescent Antibody Technique ; Granzymes/biosynthesis ; Granzymes/immunology ; Macaca mulatta ; Perforin/biosynthesis ; Perforin/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.
    Autorzy:
    Policicchio BB; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Xu C; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Brocca-Cofano E; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Raehtz KD; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    He T; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Ma D; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Li H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Sivanandham R; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Haret-Richter GS; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Dunsmore T; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Trichel A; Division of Laboratory Animal Resources, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Mellors JW; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Hahn BH; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Shaw GM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Ribeiro RM; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.
    Pandrea I; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Apetrei C; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Sep 15; Vol. 12 (9), pp. e1005879. Date of Electronic Publication: 2016 Sep 15 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Anti-Retroviral Agents/*pharmacology
    Depsipeptides/*pharmacology
    Simian Acquired Immunodeficiency Syndrome/*drug therapy
    Simian Immunodeficiency Virus/*physiology
    Virus Replication/*drug effects
    Animals ; CD8-Positive T-Lymphocytes/metabolism ; Macaca mulatta ; RNA, Viral/blood ; Simian Acquired Immunodeficiency Syndrome/blood ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
    Autorzy:
    Santra S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Tomaras GD; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Warrier R; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Nicely NI; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Liao HX; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Pollara J; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Liu P; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Alam SM; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Zhang R; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Cocklin SL; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Shen X; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Duffy R; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Xia SM; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Schutte RJ; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Pemble Iv CW; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Dennison SM; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Li H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Chao A; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Vidnovic K; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Evans A; Department of Medicine, St Mary's Campus, Imperial College London, London, United Kingdom.
    Klein K; Department of Medicine, St Mary's Campus, Imperial College London, London, United Kingdom.
    Kumar A; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Robinson J; Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.
    Landucci G; Division of Infectious Diseases, Department of Medicine, University of California, Irvine, Irvine, California, United States of America.
    Forthal DN; Division of Infectious Diseases, Department of Medicine, University of California, Irvine, Irvine, California, United States of America.
    Montefiori DC; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Kaewkungwal J; Tropical Hygiene, Mahidol University, Bangkok, Thailand.
    Nitayaphan S; Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.
    Pitisuttithum P; Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand.
    Rerks-Ngarm S; Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
    Robb ML; US Military Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
    Michael NL; US Military Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
    Kim JH; US Military Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
    Soderberg KA; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Giorgi EE; Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.
    Blair L; Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.
    Korber BT; Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.
    Moog C; U1109, INSERM University of Strasbourg, Strasbourg, Alsace, France.
    Shattock RJ; Department of Medicine, St Mary's Campus, Imperial College London, London, United Kingdom.
    Letvin NL; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Schmitz JE; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Moody MA; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Gao F; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Ferrari G; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Shaw GM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Haynes BF; Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America.
    Pokaż więcej
    Źródło:
    PLoS pathogens [PLoS Pathog] 2015 Aug 03; Vol. 11 (8), pp. e1005042. Date of Electronic Publication: 2015 Aug 03 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Monoclonal/*immunology
    Antibodies, Viral/*immunology
    Simian Acquired Immunodeficiency Syndrome/*prevention & control
    Simian Immunodeficiency Virus/*immunology
    Viral Envelope Proteins/*immunology
    Animals ; CD4-Positive T-Lymphocytes/immunology ; Fluorescent Antibody Technique ; HIV-1/immunology ; Humans ; Intestinal Mucosa/virology ; Macaca mulatta ; Protein Conformation ; Rectum ; Reverse Transcriptase Polymerase Chain Reaction ; Surface Plasmon Resonance ; Viral Envelope Proteins/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz.
    Autorzy:
    Keele BF; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
    Jones JH
    Terio KA
    Estes JD
    Rudicell RS
    Wilson ML
    Li Y
    Learn GH
    Beasley TM
    Schumacher-Stankey J
    Wroblewski E
    Mosser A
    Raphael J
    Kamenya S
    Lonsdorf EV
    Travis DA
    Mlengeya T
    Kinsel MJ
    Else JG
    Silvestri G
    Goodall J
    Sharp PM
    Shaw GM
    Pusey AE
    Hahn BH
    Pokaż więcej
    Źródło:
    Nature [Nature] 2009 Jul 23; Vol. 460 (7254), pp. 515-9.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Pan troglodytes/*virology
    Simian Acquired Immunodeficiency Syndrome/*mortality
    Simian Acquired Immunodeficiency Syndrome/*pathology
    Simian Immunodeficiency Virus/*physiology
    Acquired Immunodeficiency Syndrome/pathology ; Africa ; Animals ; Animals, Wild ; CD4-Positive T-Lymphocytes/immunology ; Female ; Humans ; Male ; Molecular Sequence Data ; Prevalence ; Simian Acquired Immunodeficiency Syndrome/epidemiology ; Simian Acquired Immunodeficiency Syndrome/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human immunodeficiency viruses: SIV infection in wild gorillas.
    Autorzy:
    Van Heuverswyn F; UMR145, Institut de Recherche pour le Développement and Department of International Health, University of Montpellier 1, 34394 Montpellier Cedex 5, France.
    Li Y
    Neel C
    Bailes E
    Keele BF
    Liu W
    Loul S
    Butel C
    Liegeois F
    Bienvenue Y
    Ngolle EM
    Sharp PM
    Shaw GM
    Delaporte E
    Hahn BH
    Peeters M
    Pokaż więcej
    Źródło:
    Nature [Nature] 2006 Nov 09; Vol. 444 (7116), pp. 164.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Animals, Wild/*virology
    Gorilla gorilla/*virology
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*isolation & purification
    Animals ; Cameroon/epidemiology ; Feces/virology ; Gorilla gorilla/classification ; Humans ; Pan troglodytes/virology ; Simian Acquired Immunodeficiency Syndrome/epidemiology ; Simian Acquired Immunodeficiency Syndrome/transmission ; Simian Immunodeficiency Virus/classification ; Zoonoses/transmission ; Zoonoses/virology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Chimpanzee reservoirs of pandemic and nonpandemic HIV-1.
    Autorzy:
    Keele BF; Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
    Van Heuverswyn F
    Li Y
    Bailes E
    Takehisa J
    Santiago ML
    Bibollet-Ruche F
    Chen Y
    Wain LV
    Liegeois F
    Loul S
    Ngole EM
    Bienvenue Y
    Delaporte E
    Brookfield JF
    Sharp PM
    Shaw GM
    Peeters M
    Hahn BH
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2006 Jul 28; Vol. 313 (5786), pp. 523-6. Date of Electronic Publication: 2006 May 25.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Disease Outbreaks*
    Disease Reservoirs*
    HIV Infections/*virology
    HIV-1/*genetics
    Pan troglodytes/*virology
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*genetics
    Animals ; Antibodies, Viral/analysis ; Ape Diseases/epidemiology ; Ape Diseases/virology ; Cameroon/epidemiology ; DNA, Mitochondrial/genetics ; Feces/virology ; HIV Antibodies/analysis ; HIV Infections/epidemiology ; HIV-1/classification ; Haplotypes ; Humans ; Molecular Epidemiology ; Molecular Sequence Data ; Pan troglodytes/classification ; Phylogeny ; Prevalence ; Recombination, Genetic ; Simian Acquired Immunodeficiency Syndrome/epidemiology ; Simian Immunodeficiency Virus/classification ; Simian Immunodeficiency Virus/immunology ; Simian Immunodeficiency Virus/isolation & purification
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeat.
    Autorzy:
    Peeters M; Institue de Recherche pour la Développement, Laboratoire Retrovirus, 911 Avenue Agropolis, BP 5045, 34032 Montpellier cedex 1, France. />Courgnaud V
    Abela B
    Auzel P
    Pourrut X
    Bibollet-Ruche F
    Loul S
    Liegeois F
    Butel C
    Koulagna D
    Mpoudi-Ngole E
    Shaw GM
    Hahn BH
    Delaporte E
    Pokaż więcej
    Źródło:
    Emerging infectious diseases [Emerg Infect Dis] 2002 May; Vol. 8 (5), pp. 451-7.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Haplorhini/*virology
    Meat/*virology
    Simian Acquired Immunodeficiency Syndrome/*transmission
    Simian Immunodeficiency Virus/*isolation & purification
    Animals ; Animals, Domestic/blood ; Animals, Domestic/immunology ; Animals, Domestic/virology ; Animals, Wild/blood ; Animals, Wild/immunology ; Animals, Wild/virology ; Cameroon ; Cross Reactions ; Evolution, Molecular ; HIV/immunology ; Haplorhini/blood ; Haplorhini/immunology ; Humans ; Immune Sera/immunology ; Molecular Sequence Data ; Phylogeny ; Polymerase Chain Reaction ; Prevalence ; Risk Factors ; Serologic Tests ; Simian Acquired Immunodeficiency Syndrome/blood ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/genetics ; Simian Immunodeficiency Virus/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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