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Wyświetlanie 1-8 z 8
Tytuł:
Capsule-Negative emm Types Are an Increasing Cause of Pediatric Group A Streptococcal Infections at a Large Pediatric Hospital in Texas.
Autorzy:
Flores AR; Division of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Sciences Center at Houston.
Chase McNeil J; Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
Shah B; Division of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Sciences Center at Houston.
Van Beneden C; Respiratory Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Shelburne SA; Division of Internal Medicine, Departments of Infectious Diseases and Genomic Medicine, MD Anderson Cancer Center, Houston, Texas.
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Źródło:
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2019 Jul 01; Vol. 8 (3), pp. 244-250.
Typ publikacji:
Journal Article
MeSH Terms:
Hospitals, Pediatric*
Streptococcal Infections/*epidemiology
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*isolation & purification
Adolescent ; Antigens, Bacterial/genetics ; Bacterial Outer Membrane Proteins/genetics ; Carrier Proteins/genetics ; Child ; Child, Preschool ; Female ; Genotype ; Humans ; Infant ; Male ; Pharynx/microbiology ; Prospective Studies ; Streptococcus pyogenes/genetics ; Streptococcus pyogenes/pathogenicity ; Texas/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł:
Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface.
Autorzy:
Galloway-Peña J; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
DebRoy S; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Brumlow C; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Li X; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Tran TT; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, United States of America.
Horstmann N; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Yao H; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Chen K; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Wang F; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Pan BF; The Proteomics and Metabolomics Facility, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Hawke DH; The Proteomics and Metabolomics Facility, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Thompson EJ; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Arias CA; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, United States of America.; Center for Infectious Diseases, UTHealth School of Public Health, Houston, Texas, United States of America.; Molecular Genetics and Antimicrobial Resistance Unit-International Center for Microbial Genomics, Universidad El Bosque, Bogota, Colombia.
Fowler VG Jr; Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America.
Bhatti MM; Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Kalia A; Graduate Program in Diagnostic Genetics, School of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Flores AR; Center for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, United States of America.; Department of Pediatrics, University of Texas Health Science Center McGovern Medical School, Houston, Texas, United States of America.
Shelburne SA; Department of Infectious Diseases Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; The Proteomics and Metabolomics Facility, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Dec 05; Vol. 13 (12), pp. e0207897. Date of Electronic Publication: 2018 Dec 05 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Streptococcus pyogenes/*pathogenicity
Animals ; Bacterial Capsules/genetics ; Bacterial Capsules/ultrastructure ; Bacterial Proteins/genetics ; Cell Membrane/genetics ; Cell Membrane/ultrastructure ; Female ; Genes, Bacterial ; Histidine Kinase ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Mice ; Microscopy, Electron, Transmission ; Mutation ; Regulon ; Repressor Proteins/genetics ; Serogroup ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/genetics ; Streptococcus pyogenes/ultrastructure ; Virulence/genetics ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł:
Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus.
Autorzy:
Horstmann N; Department of Infectious Diseases, Infection Control and Employee Health, MD Anderson Cancer Center, Houston TX, United States of America.
Tran CN; Department of Infectious Diseases, Infection Control and Employee Health, MD Anderson Cancer Center, Houston TX, United States of America.
Brumlow C; Department of Infectious Diseases, Infection Control and Employee Health, MD Anderson Cancer Center, Houston TX, United States of America.
DebRoy S; Department of Infectious Diseases, Infection Control and Employee Health, MD Anderson Cancer Center, Houston TX, United States of America.
Yao H; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston TX, United States of America.
Nogueras Gonzalez G; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston TX, United States of America.
Makthal N; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, United States of America.
Kumaraswami M; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, United States of America.
Shelburne SA; Department of Infectious Diseases, Infection Control and Employee Health, MD Anderson Cancer Center, Houston TX, United States of America.; Department of Genomic Medicine, MD Anderson Cancer Center, Houston TX, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2018 Oct 31; Vol. 14 (10), pp. e1007354. Date of Electronic Publication: 2018 Oct 31 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Bacterial Proteins/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Nasopharynx/*microbiology
Phosphoric Monoester Hydrolases/*metabolism
Skin/*microbiology
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*pathogenicity
Animals ; Bacterial Proteins/genetics ; Gene Expression Regulation, Bacterial ; Histidine Kinase ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Mice ; Mice, Hairless ; Nasopharynx/enzymology ; Phosphoric Monoester Hydrolases/genetics ; Phosphorylation ; Serogroup ; Skin/enzymology ; Streptococcal Infections/enzymology ; Streptococcus pyogenes/enzymology ; Virulence
Czasopismo naukowe
Tytuł:
A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus.
Autorzy:
DebRoy S; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.
Saldaña M; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.
Travisany D; Mathomics, Center for Mathematical Modeling, Universidad de Chile, Beauchef 851, 7th Floor, Santiago, Chile.; Center for Genome Regulation (Fondap 15090007), Universidad de Chile, Blanco Encalada 2085, Santiago, Chile.
Montano A; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.
Galloway-Peña J; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.
Horstmann N; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.
Yao H; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, Texas, USA.
González M; Center for Genome Regulation (Fondap 15090007), Universidad de Chile, Blanco Encalada 2085, Santiago, Chile.; Laboratorio de Bioinformática y Expresión Génica, INTA, Universidad de Chile, El Líbano 5524, Macul, Santiago, Chile.
Maass A; Mathomics, Center for Mathematical Modeling, Universidad de Chile, Beauchef 851, 7th Floor, Santiago, Chile.; Center for Genome Regulation (Fondap 15090007), Universidad de Chile, Blanco Encalada 2085, Santiago, Chile.; Department of Mathematical Engineering, Universidad de Chile, Beauchef 851, 5th Floor, Santiago, Chile.
Latorre M; Mathomics, Center for Mathematical Modeling, Universidad de Chile, Beauchef 851, 7th Floor, Santiago, Chile.; Center for Genome Regulation (Fondap 15090007), Universidad de Chile, Blanco Encalada 2085, Santiago, Chile.; Laboratorio de Bioinformática y Expresión Génica, INTA, Universidad de Chile, El Líbano 5524, Macul, Santiago, Chile.
Shelburne SA; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA.; Department of Genomic Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło:
Scientific reports [Sci Rep] 2016 Sep 01; Vol. 6, pp. 32442. Date of Electronic Publication: 2016 Sep 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Bacterial*
Regulon*
Transcriptome*
Bacterial Proteins/*genetics
Repressor Proteins/*genetics
Streptococcus pyogenes/*genetics
Streptococcus pyogenes/*pathogenicity
Animals ; Bacterial Proteins/metabolism ; Female ; Gene Expression Profiling ; Humans ; Mice ; Nucleotide Motifs ; Repressor Proteins/metabolism ; Serogroup ; Streptococcal Infections/microbiology ; Streptococcal Infections/mortality ; Streptococcal Infections/pathology ; Streptococcus pyogenes/classification ; Streptococcus pyogenes/metabolism ; Survival Analysis ; Virulence
Czasopismo naukowe
Tytuł:
Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis.
Autorzy:
Horstmann N; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, United States of America.
Saldaña M; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, United States of America.
Sahasrabhojane P; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, United States of America.
Yao H; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, Texas, United States of America.
Su X; Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, Texas, United States of America.
Thompson E; DNA Sequencing Facility, MD Anderson Cancer Center, Houston, Texas, United States of America.
Koller A; Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America.
Shelburne SA 3rd; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, United States of America; Department of Genomic Medicine, MD Anderson Cancer Center, Houston, Texas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2014 May 01; Vol. 10 (5), pp. e1004088. Date of Electronic Publication: 2014 May 01 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Processing, Post-Translational*/physiology
Bacterial Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
Repressor Proteins/*metabolism
Streptococcus pyogenes/*genetics
Streptococcus pyogenes/*pathogenicity
Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Female ; Gene Expression Regulation, Bacterial ; Host-Pathogen Interactions/genetics ; Mice ; Microarray Analysis ; Mutation, Missense ; Phosphorylation/physiology ; Protein Interaction Domains and Motifs ; Repressor Proteins/chemistry ; Repressor Proteins/genetics ; Streptococcal Infections/genetics ; Streptococcal Infections/metabolism ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/metabolism
Czasopismo naukowe
Tytuł:
Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis.
Autorzy:
Horstmann N; Department of Biochemistry and Molecular Biology, MD Anderson Cancer Center, Houston, Texas, United States of America.
Sahasrabhojane P
Suber B
Kumaraswami M
Olsen RJ
Flores A
Musser JM
Brennan RG
Shelburne SA 3rd
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Źródło:
PLoS pathogens [PLoS Pathog] 2011 Oct; Vol. 7 (10), pp. e1002311. Date of Electronic Publication: 2011 Oct 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acid Substitution*
Amino Acids/*chemistry
Bacterial Proteins/*chemistry
Bacterial Proteins/*genetics
Repressor Proteins/*chemistry
Repressor Proteins/*genetics
Streptococcus pyogenes/*genetics
Animals ; Bacterial Proteins/metabolism ; Base Sequence ; DNA, Bacterial/analysis ; Disease Models, Animal ; Female ; Longevity ; Mice ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Polymorphism, Single Nucleotide ; Protein Structure, Secondary ; RNA, Bacterial/analysis ; Repressor Proteins/metabolism ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/pathogenicity ; Virulence/genetics
Czasopismo naukowe
Tytuł:
A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.
Autorzy:
Shelburne SA; Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, United States of America.
Olsen RJ
Suber B
Sahasrabhojane P
Sumby P
Brennan RG
Musser JM
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Źródło:
PLoS pathogens [PLoS Pathog] 2010 Mar 19; Vol. 6 (3), pp. e1000817. Date of Electronic Publication: 2010 Mar 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Streptococcus pyogenes*/genetics
Streptococcus pyogenes*/growth & development
Streptococcus pyogenes*/pathogenicity
Bacterial Proteins/*genetics
Repressor Proteins/*genetics
Streptococcal Infections/*microbiology
Transcriptional Activation/*physiology
Animals ; Animals, Outbred Strains ; Bacterial Proteins/metabolism ; Female ; Gene Expression Regulation, Bacterial ; Humans ; Mice ; Phosphorylation/physiology ; Promoter Regions, Genetic/physiology ; RNA, Messenger/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Repressor Proteins/metabolism ; Saliva/microbiology ; Virulence ; Virulence Factors/genetics ; Virulence Factors/metabolism
Czasopismo naukowe
Tytuł:
Molecular mechanisms underlying group A streptococcal pathogenesis.
Autorzy:
Olsen RJ; Center for Molecular and Translational Human Infectious Disease Research, The Methodist Hospital Research Institute, Houston, TX 77030, USA.
Shelburne SA
Musser JM
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Źródło:
Cellular microbiology [Cell Microbiol] 2009 Jan; Vol. 11 (1), pp. 1-12. Date of Electronic Publication: 2008 Aug 15.
Typ publikacji:
Journal Article
MeSH Terms:
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*pathogenicity
Streptococcus pyogenes/*physiology
Animals ; Host-Pathogen Interactions ; Humans ; Mice ; Models, Animal
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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