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Tytuł:
An Integrated Research-Clinical BSL-2 Platform for a Live SARS-CoV-2 Neutralization Assay.
Autorzy:
Zou J; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Kurhade C; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Chang HC; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Hu Y; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Meza JA; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Beaver D; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Trinh K; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Omlid J; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Elghetany B; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Desai R; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
McCaffrey P; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Garcia JD; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Shi PY; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Ren P; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xie X; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.; Sealy Institute for Drug Discovery, University of Texas Medical Branch, Galveston, TX 77555, USA.
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Źródło:
Viruses [Viruses] 2023 Aug 31; Vol. 15 (9). Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Immunogenicity and Safety of a Third COVID-19 BNT162b2 mRNA Vaccine Dose in 5- to 11-Year Olds.
Autorzy:
Simões EAF; Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA.
Klein NP; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California, Oakland, CA, USA.
Sabharwal C; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Gurtman A; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Kitchin N; Vaccine Research and Development, Pfizer Ltd, Hurley, UK.
Ukkonen B; Espoo Vaccine Research Clinic, Tampere University, Espoo, Finland.
Korbal P; Ośrodek Badań Klinicznych In-Vivo, Bydgoszcz-Toruń, Poland.
Zou J; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Sarwar UN; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Xu X; Vaccine Research and Development, Pfizer Inc, Collegeville, PA, USA.
Lockhart S; Vaccine Research and Development, Pfizer Ltd, Hurley, UK.
Cunliffe L; Vaccine Research and Development, Pfizer Ltd, Hurley, UK.
Lu C; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Ma H; Vaccine Research and Development, Pfizer Inc, Collegeville, PA, USA.
Swanson KA; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Koury K; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Shi PY; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Cooper D; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Türeci Ӧ; BioNTech, Mainz, Germany.
Jansen KU; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
Şahin U; BioNTech, Mainz, Germany.
Gruber WC; Vaccine Research and Development, Pfizer Inc, Pearl River, NY, USA.
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Źródło:
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2023 Apr 28; Vol. 12 (4), pp. 234-238.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
BNT162 Vaccine*
COVID-19*/prevention & control
Humans ; Antibodies, Viral ; Immunogenicity, Vaccine ; SARS-CoV-2 ; mRNA Vaccines
Czasopismo naukowe
Tytuł:
Positive-strand RNA viruses-a Keystone Symposia report.
Autorzy:
Cable J; PhD Science Writer, New York, New York, USA.
Denison MR; Department of Pediatrics and Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center; and Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, Tennessee, USA.
Kielian M; Department of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
Jackson WT; Department of Microbiology and Immunology and Center for Pathogen Research, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Bartenschlager R; Department of Infectious Diseases, Molecular Virology, Heidelberg University and German Cancer Research Center (DKFZ), Research Division Virus-associated Carcinogenesis, Heidelberg, Germany.
Ahola T; Department of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland.
Mukhopadhyay S; Department of Biology, Indiana University, Bloomington, Indiana, USA.
Fremont DH; Department of Pathology & Immunology; Department of Molecular Microbiology; and Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Kuhn RJ; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.
Shannon A; Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix Marseille Université, Marseille, France.
Frazier MN; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.
Yuen KY; Department of Microbiology, Li Ka Shing Faculty of Medicine and State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong, People's Republic of China.
Coyne CB; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Wolthers KC; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam and Amsterdam Institute for Infection and Immunity, OrganoVIR Labs, Amsterdam, The Netherlands.
Ming GL; Department of Neuroscience and Mahoney Institute for Neurosciences, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Guenther CS; Colorado State University, Fort Collins, Colorado, USA.
Moshiri J; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Best SM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Schoggins JW; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jurado KA; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ebel GD; Center for Vector-borne Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ng LFP; ASTAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science Technology and Research (A*STAR), Singapore City, Singapore.; National Institute of Health Research, Health Protection Research Unit in Emerging and Zoonotic Infections; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Kikkert M; Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, California, USA.; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, California, USA.
Harris E; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA.
Wing PAC; Nuffield Department of Medicine and Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK.
Eggenberger J; Department of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.
Krishnamurthy SR; Metaorganism Immunity Section, Laboratory of Immune System Biology and NIAID Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Mah MG; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore City, Singapore.
Meganck RM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Chung D; Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, Texas, USA.
Maurer-Stroh S; Yong Loo Lin School of Medicine and Department of Biological Sciences, National University of Singapore, Singapore City, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore City, Singapore.
Andino R; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Korber B; Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
Perlman S; Department of Microbiology and Immunology, and Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.
Shi PY; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.
Bárcena M; Section Electron Microscopy, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Aicher SM; Institut Pasteurgrid, Université de Paris Cité, Virus Sensing and Signaling Unit, Paris, France.
Vu MN; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Kenney DJ; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, USA.
Lindenbach BD; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA.
Nishida Y; Chugai Pharmaceutical, Co., Tokyo, Japan.; Lee Kong Chian School of Medicine and School of Biological Sciences, Nanyang Technological University, Singapore City, Singapore.
Rénia L; ASTAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science Technology and Research (A*STAR), Singapore City, Singapore.
Williams EP; Department of Microbiology, Immunology, and Biochemistry, The University of Tennessee Health Science Center, Memphis, Tennessee, USA.
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Źródło:
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2023 Mar; Vol. 1521 (1), pp. 46-66. Date of Electronic Publication: 2023 Jan 25.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural
MeSH Terms:
COVID-19*
Zika Virus*
Zika Virus Infection*/epidemiology
Zika Virus Infection*/prevention & control
Zika Virus Infection*/drug therapy
Humans ; SARS-CoV-2 ; Positive-Strand RNA Viruses ; Antiviral Agents/therapeutic use ; Pandemics
Czasopismo naukowe
Tytuł:
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Autorzy:
Radoshitzky SR; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.; Division of Antivirals, Office of Infectious Diseases, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Iversen P; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.
Lu X; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Zou J; Department of Biochemistry & Molecular Biology, Institute for Drug Discovery, Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA.
Kaptein SJF; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, B-3000, Leuven, Belgium.; Global Virus Network, GVN, Baltimore, USA.
Stuthman KS; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.
Van Tongeren SA; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.
Steffens J; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.
Gong R; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Truong H; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Sapre AA; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Yang H; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Xie X; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Chia JJ; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Song ZJ; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Leventhal SM; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Chan J; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Shornikov A; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Zhang X; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, B-3000, Leuven, Belgium.; Global Virus Network, GVN, Baltimore, USA.
Cowfer D; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Yu H; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Warren T; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.; Laulima Government Solutions, LLC., Orlando, FL, USA.
Cihlar T; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Porter DP; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, B-3000, Leuven, Belgium.; Global Virus Network, GVN, Baltimore, USA.
Shi PY; Department of Biochemistry & Molecular Biology, Institute for Drug Discovery, Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA.
Wells J; The Geneva Foundation, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA.
Bilello JP; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA.
Feng JY; Gilead Sciences, Inc, 333 Lakeside Drive, Foster City, CA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 23; Vol. 13 (1), pp. 3131. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hemorrhagic Fever, Ebola*/drug therapy
Filoviridae*
Zika Virus*
Zika Virus Infection*/drug therapy
Humans ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Adenosine Monophosphate ; Alanine
Czasopismo naukowe
Tytuł:
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.
Autorzy:
Richards CM; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Jabs S; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Qiao W; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Varanese LD; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Schweizer M; Department of Electron Microscopy, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mosen PR; Institute for Biochemistry and Molecular Biology, Medical Faculty, Rheinische Friedrich-Wilhelms-University of Bonn, Bonn, Germany.
Riley NM; Department of Chemistry, Stanford University, Stanford, CA, USA.
Klüssendorf M; Department of Osteology and Biomechanics, Cell Biology of Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Zengel JR; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Flynn RA; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA.; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA, USA.
Rustagi A; Division of Infectious Disease and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Widen JC; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Peters CE; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Ooi YS; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Shi PY; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Bartenschlager R; Department of Infectious Diseases, Molecular Virology, Heidelberg University, Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Puschnik AS; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Bogyo M; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Bertozzi CR; Department of Chemistry, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford, CA, USA.
Blish CA; Division of Infectious Disease and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Winter D; Institute for Biochemistry and Molecular Biology, Medical Faculty, Rheinische Friedrich-Wilhelms-University of Bonn, Bonn, Germany.
Nagamine CM; Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Braulke T; Department of Osteology and Biomechanics, Cell Biology of Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Carette JE; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Oct 07; Vol. 378 (6615), pp. eabn5648. Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
Lysosomes*/metabolism
Mucolipidoses*/genetics
Mucolipidoses*/metabolism
Proteins*/genetics
Animals ; Cathepsins/metabolism ; Humans ; Mannose/metabolism ; Mice ; Mice, Knockout ; Transferases (Other Substituted Phosphate Groups)
Czasopismo naukowe
Tytuł:
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Autorzy:
Johnson BA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Zhou Y; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Lokugamage KG; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Vu MN; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Bopp N; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Crocquet-Valdes PA; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Kalveram B; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Schindewolf C; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Liu Y; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Scharton D; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.
Plante JA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.
Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Aguilar P; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.
Weaver SC; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America.
Shi PY; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America.; Institute for Drug Discovery, University of Texas Medical Branch, Galveston, Texas, United States of America.
Walker DH; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America.; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.
Routh AL; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, Texas, United States of America.
Plante KS; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.
Menachery VD; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.; World Reference Center of Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, United States of America.; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2022 Jun 21; Vol. 18 (6), pp. e1010627. Date of Electronic Publication: 2022 Jun 21 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
COVID-19*/genetics
SARS-CoV-2*/genetics
Glycogen Synthase Kinase 3 ; Humans ; Mutation ; Nucleocapsid ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
A Single-Round Infection Fluorescent SARS-CoV-2 Neutralization Test for COVID-19 Serological Testing at a Biosafety Level-2 Laboratory.
Autorzy:
Zou J; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xia H; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Shi PY; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555, USA.; Sealy Institute for Drug Discovery, University of Texas Medical Branch, Galveston, TX 77555, USA.; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA.; Sealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA.; Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xie X; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555, USA.
Ren P; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555, USA.; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
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Źródło:
Viruses [Viruses] 2022 Jun 02; Vol. 14 (6). Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/diagnosis
SARS-CoV-2*
Antibodies, Neutralizing ; Antibodies, Viral ; COVID-19 Serological Testing ; Containment of Biohazards ; Humans ; Laboratories ; Neutralization Tests ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.
Autorzy:
Dorjsuren D; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Eastman RT; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Song MJ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Yasgar A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Chen Y; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Bharti K; Unit on Ocular and Stem Cell Translational Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Zakharov AV; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Jadhav A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Ferrer M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
Shi PY; University of Texas Medical Branch Galveston, Galveston, TX, United States of America.
Simeonov A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Jan 18; Vol. 17 (1), pp. e0261821. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Printing, Three-Dimensional*
Retina*/metabolism
Retina*/virology
Zika Virus Infection*/drug therapy
Zika Virus Infection*/genetics
Zika Virus Infection*/metabolism
Antiviral Agents/*pharmacology
Virus Replication/*drug effects
Zika Virus/*physiology
Animals ; Antiviral Agents/chemistry ; Chlorocebus aethiops ; Drug Evaluation, Preclinical ; Hep G2 Cells ; Humans ; Vero Cells ; Virus Replication/genetics
Czasopismo naukowe

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