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Wyszukujesz frazę ""Shultz, Leonard D."" wg kryterium: Autor


Wyświetlanie 1-16 z 16
Tytuł :
Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
Autorzy :
Friedline RH; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Ko HJ; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Jung DY; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Lee Y; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Bortell R; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Dagdeviren S; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Patel PR; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Hu X; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Inashima K; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Kearns C; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Tsitsilianos N; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Shafiq U; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Shultz LD; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Lee KW; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Greiner DL; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Kim JK; Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea .
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2016 Mar; Vol. 30 (3), pp. 1328-38. Date of Electronic Publication: 2015 Dec 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance/*physiology
Interleukin-2/*metabolism
Lymphocytes/*metabolism
Mice, Inbred NOD/*metabolism
Obesity/*metabolism
Animals ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/physiopathology ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/physiopathology ; Diet, High-Fat/adverse effects ; Dietary Fats/adverse effects ; Energy Metabolism/physiology ; Glucose/metabolism ; Glucose Clamp Technique/methods ; Insulin/metabolism ; Lymphocytes/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred NOD/physiology ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiology ; Obesity/physiopathology ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.
Autorzy :
Sewald X; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
Ladinsky MS; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Uchil PD; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
Beloor J; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Pi R; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
Herrmann C; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
Motamedi N; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Murooka TT; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Brehm MA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Greiner DL; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Shultz LD; The Jackson Laboratory, Bar Harbor, ME 04609, USA..
Mempel TR; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Kumar P; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2015 Oct 30; Vol. 350 (6260), pp. 563-567. Date of Electronic Publication: 2015 Oct 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
HIV Infections/*immunology
HIV-1/*physiology
Leukemia Virus, Murine/*physiology
Lymphocytes/*virology
Retroviridae Infections/*immunology
Sialic Acid Binding Ig-like Lectin 1/*physiology
Animals ; Dendritic Cells/immunology ; Dendritic Cells/virology ; Humans ; Lymph Nodes/immunology ; Lymph Nodes/virology ; Lymphocytes/immunology ; Macrophages/immunology ; Macrophages/virology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Sialic Acid Binding Ig-like Lectin 1/genetics ; Spleen/immunology ; Spleen/virology
Czasopismo naukowe
Tytuł :
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Autorzy :
Unsinger J; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
McDonough JS
Shultz LD
Ferguson TA
Hotchkiss RS
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2009 Aug; Vol. 86 (2), pp. 219-27. Date of Electronic Publication: 2009 Apr 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*immunology
Cytokines/*metabolism
Hematopoietic Stem Cell Transplantation/*methods
Inflammation/*immunology
Lymphocytes/*immunology
Systemic Inflammatory Response Syndrome/*immunology
Adoptive Transfer/methods ; Animals ; Animals, Newborn ; Cell Lineage/immunology ; Cell Proliferation ; Cells, Cultured ; Cord Blood Stem Cell Transplantation/methods ; Disease Models, Animal ; Graft Survival/immunology ; Hematopoietic Stem Cells/immunology ; Humans ; Immunity, Innate/immunology ; Inflammation/physiopathology ; Lymphocyte Activation/immunology ; Lymphocytes/metabolism ; Mice ; Mice, Knockout ; Mice, SCID ; Systemic Inflammatory Response Syndrome/physiopathology
Czasopismo naukowe
Tytuł :
Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.
Autorzy :
Banuelos SJ; Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Shultz LD
Greiner DL
Burzenski LM
Gott B
Lyons BL
Rossini AA
Appel MC
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Źródło :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2004 Sep; Vol. 112 (3), pp. 273-83.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Genes, RAG-1/*genetics
Graft Rejection/*immunology
HLA-A2 Antigen/*immunology
Islets of Langerhans/*immunology
Islets of Langerhans Transplantation/*immunology
Lymphocytes/*immunology
Severe Combined Immunodeficiency/*immunology
Animals ; Blood Glucose/analysis ; Diabetes Mellitus/blood ; Diabetes Mellitus/chemically induced ; Diabetes Mellitus/immunology ; Diabetes Mellitus/surgery ; Gene Deletion ; Graft vs Host Disease/immunology ; Humans ; Membrane Glycoproteins/deficiency ; Membrane Glycoproteins/genetics ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, Transgenic ; Perforin ; Pore Forming Cytotoxic Proteins ; Spleen/immunology ; Transplantation, Homologous/immunology
Czasopismo naukowe
Tytuł :
Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice.
Autorzy :
Turgeon NA; University of Massachusetts Medical School, Worcester, Massachussetts 01605, USA.
Banuelos SJ
Shultz LD
Lyons BL
Iwakoshi N
Greiner DL
Mordes JP
Rossini AA
Appel MC
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Źródło :
Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2003 Oct; Vol. 228 (9), pp. 1096-104.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Graft vs Host Disease*
Lymphocytes/*cytology
Skin Transplantation/*immunology
Animals ; CD3 Complex/biosynthesis ; CD4 Antigens/biosynthesis ; CD8 Antigens/biosynthesis ; Female ; Flow Cytometry ; Graft Rejection ; Humans ; Immunohistochemistry ; Leukocyte Common Antigens/biosynthesis ; Leukocytes, Mononuclear/metabolism ; Lymphocytes/metabolism ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Receptors, Interleukin-2/biosynthesis ; Spleen/cytology ; beta 2-Microglobulin/genetics
Czasopismo naukowe
Tytuł :
Antibody Repertoires in Humanized NOD-scid-IL2Rγ Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse.
Autorzy :
Ippolito, Gregory C.
Kam Hon Hoi
Reddy, Sai T.
Carroll, Sean M.
Xin Ge
Rogosch, Tobias
Zemlin, Michael
Shultz, Leonard D.
Ellington, Andrew D.
VanDenBerg, Carla L.
Georgiou, George
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Temat :
ANTIGEN presenting cells
IMMUNOGLOBULIN genes
B cells
STEM cells
LYMPHOCYTES
BONE marrow cells
HEMATOPOIETIC stem cells
Źródło :
PLoS ONE; Apr2012, Vol. 7 Issue 4, p1-15, 15p
Czasopismo naukowe
Tytuł :
HLA-A2-Matched Peripheral Blood Mononuclear Cells From Type 1 Diabetic Patients, but Not Nondiabetic Donors, Transfer Insulitis to NOD-scid/γc T cells.
Autorzy :
Whitfield-Larry, Fatima
Young, Ellen F.
Talmage, Garrick
Fudge, Elizabeth
Azam, Anita
Patel, Shipra
Largay, Joseph
Byrd, Warren
Buse, John
Calikoglu, Ali S.
Shultz, Leonard D.
Frelinger, Jeffrey A.
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Temat :
DIABETES
AUTOIMMUNE diseases
INSULIN
LYMPHOCYTES
T cells
PEPTIDES
Źródło :
Diabetes; Jun2011, Vol. 60 Issue 6, p1726-1733, 8p
Czasopismo naukowe
Tytuł :
Human Nasal Polyp Microenvironments Maintained in a Viable and Functional State as Xenografts in NOD-scid IL2ry Mice.
Autorzy :
Bernstein, Joel M.
Brooks, Stephen P.
Lehman, Heather K.
Pope, Liza
Sands, Amy
Shultz, Leonard D.
Bankert, Richard B.
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Temat :
TRANSPLANTATION of organs, tissues, etc.
POLYPS
NASAL tumors
LYMPHOCYTES
KILLER cells
Źródło :
Annals of Otology, Rhinology & Laryngology; Dec2009, Vol. 118 Issue 12, p866-875, 10p
Czasopismo naukowe
    Wyświetlanie 1-16 z 16

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