Improved B cell development in humanized NOD -scid IL2Rγ mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3.
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.
Autorzy:
Sewald X; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA. Ladinsky MS; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Uchil PD; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA. Beloor J; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA. Pi R; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA. Herrmann C; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA. Motamedi N; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA. Murooka TT; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Brehm MA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA. Greiner DL; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA. Shultz LD; The Jackson Laboratory, Bar Harbor, ME 04609, USA.. Mempel TR; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Kumar P; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA. Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2015 Oct 30; Vol. 350 (6260), pp. 563-567. Date of Electronic Publication: 2015 Oct 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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