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Tytuł :
Pan-cancer analysis reveals that neurotrophin signaling correlates positively with anti-tumor immunity, clinical outcomes, and response to targeted therapies and immunotherapies in cancer.
Autorzy :
Feng Q; Biomedical Informatics Research Lab, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Cancer Genomics Research Center, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Big Data Research Institute, China Pharmaceutical University, Nanjing 211198, China.
Song D; Biomedical Informatics Research Lab, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Cancer Genomics Research Center, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Big Data Research Institute, China Pharmaceutical University, Nanjing 211198, China.
Wang X; Biomedical Informatics Research Lab, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Cancer Genomics Research Center, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; Big Data Research Institute, China Pharmaceutical University, Nanjing 211198, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119848. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/immunology
Databases, Genetic*
Immunotherapy*
Neoplasm Proteins*/genetics
Neoplasm Proteins*/immunology
Neoplasms*/genetics
Neoplasms*/immunology
Neoplasms*/therapy
Nerve Growth Factors*/genetics
Nerve Growth Factors*/immunology
Signal Transduction*/genetics
Signal Transduction*/immunology
Humans
Czasopismo naukowe
Tytuł :
TLR7 Agonist Suppresses Group 2 Innate Lymphoid Cell-mediated Inflammation via IL-27-Producing Interstitial Macrophages.
Autorzy :
Okuzumi S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Miyata J; Division of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine, National Defense Medical College, Saitama, Japan; and.
Kabata H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Mochimaru T; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Kagawa S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Masaki K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Irie M; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Morita H; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Fukunaga K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 Sep; Vol. 65 (3), pp. 309-318.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Imidazoles/*pharmacology
Immunity, Innate/*drug effects
Interleukins/*immunology
Lung/*immunology
Lymphocytes/*immunology
Macrophages/*immunology
Membrane Glycoproteins/*agonists
Signal Transduction/*drug effects
Toll-Like Receptor 7/*agonists
Animals ; Asthma/genetics ; Asthma/immunology ; Asthma/pathology ; Chemokine CCL17/genetics ; Chemokine CCL17/immunology ; Chemokine CCL24/genetics ; Chemokine CCL24/immunology ; Eosinophils/immunology ; Eosinophils/pathology ; Immunity, Innate/genetics ; Inflammation/genetics ; Inflammation/immunology ; Interleukin-33/genetics ; Interleukin-33/immunology ; Interleukins/genetics ; Lung/pathology ; Lymphocytes/pathology ; Macrophages/pathology ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Receptors, Interleukin/deficiency ; Receptors, Interleukin/immunology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Toll-Like Receptor 7/genetics ; Toll-Like Receptor 7/immunology
Czasopismo naukowe
Tytuł :
Multistep Signaling in Nature: A Close-Up of Geobacter Chemotaxis Sensing.
Autorzy :
Silva MA; Associate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.
Salgueiro CA; Associate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.; UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 21; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Chemotaxis/*physiology
Geobacter/*physiology
Methyl-Accepting Chemotaxis Proteins/*physiology
SCR Organism :
Geobacter sulfurreducens
Czasopismo naukowe
Tytuł :
Modeling Neuroimmune Interactions in Human Subjects and Animal Models to Predict Subtype-Specific Multidrug Treatments for Gulf War Illness.
Autorzy :
Carrera Arias FJ; Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Aenlle K; Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Miami Veterans Affairs Healthcare System, Miami, FL 33125, USA.
Abreu M; Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Miami Veterans Affairs Healthcare System, Miami, FL 33125, USA.
Holschbach MA; Department of Psychology & Neuroscience, College of Psychology, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Michalovicz LT; Health Effects Laboratory Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Kelly KA; Health Effects Laboratory Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Klimas N; Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Miami Veterans Affairs Healthcare System, Miami, FL 33125, USA.
O'Callaghan JP; Health Effects Laboratory Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
Craddock TJA; Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Psychology & Neuroscience, College of Psychology, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.; Department of Computer Science, College of Engineering and Computing, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 09; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Immunological*
Models, Neurological*
Neuroimmunomodulation*
Persian Gulf Syndrome*/drug therapy
Persian Gulf Syndrome*/immunology
Signal Transduction*/drug effects
Signal Transduction*/immunology
Blood-Brain Barrier/*immunology
Adult ; Animals ; Disease Models, Animal ; Humans ; Male ; Mice ; Middle Aged
Czasopismo naukowe
Tytuł :
Evaluation of Th1 and Th2 mediated cellular and humoral immunity in patients with COVID-19 following the use of melatonin as an adjunctive treatment.
Autorzy :
Hosseini A; Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Esmaeili Gouvarchin Ghaleh H; Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Aghamollaei H; Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Fasihi Ramandi M; Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Alishiri G; Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Shahriary A; Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
Hassanpour K; Sabzevar University of Medical Sciences, School of Medicine, Sabzevar, Iran. Electronic address: .
Tat M; Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Farnoosh G; Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Aug 05; Vol. 904, pp. 174193. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/drug therapy
COVID-19*/epidemiology
COVID-19*/immunology
Melatonin*/administration & dosage
Melatonin*/immunology
Signal Transduction*/drug effects
Signal Transduction*/immunology
Th1 Cells*/drug effects
Th1 Cells*/immunology
Th2 Cells*/drug effects
Th2 Cells*/immunology
Cytokines/*blood
Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/immunology ; Female ; Humans ; Immunity, Cellular/drug effects ; Immunity, Humoral/drug effects ; Immunologic Factors/administration & dosage ; Immunologic Factors/immunology ; Iran/epidemiology ; Male ; Middle Aged ; SARS-CoV-2 ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound.
Autorzy :
Kamikaseda Y; Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan; Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Uruno T; Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Kunimura K; Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Harada A; Division of Transcriptomics, Research Center for Transomics Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Saiki K; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Oisaki K; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Sakata D; Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Nakahara T; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kido-Nakahara M; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kanai M; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Nakamura S; Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Ohkawa Y; Division of Transcriptomics, Research Center for Transomics Medicine, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Furue M; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Fukui Y; Division of Immunogenetics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 633-638. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basic Helix-Loop-Helix Transcription Factors/*antagonists & inhibitors
Dermatitis, Atopic/*immunology
Doxycycline/*pharmacology
Gene Expression Regulation/*drug effects
Interleukins/*immunology
Signal Transduction/*drug effects
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/immunology ; Dermatitis, Atopic/genetics ; Dermatitis, Atopic/pathology ; Gene Expression Regulation/immunology ; Interleukins/genetics ; Mice ; Mice, Knockout ; Promoter Regions, Genetic ; Signal Transduction/genetics ; Signal Transduction/immunology ; T-Lymphocytes, Helper-Inducer
Czasopismo naukowe
Tytuł :
How can a traffic light properly work if it is always green? The paradox of CK2 signaling.
Autorzy :
Borgo C; Department of Biomedical Sciences, University of Padova, Padova, Italy.
D'Amore C; Department of Biomedical Sciences, University of Padova, Padova, Italy.
Cesaro L; Department of Biomedical Sciences, University of Padova, Padova, Italy.
Sarno S; Department of Biomedical Sciences, University of Padova, Padova, Italy.
Pinna LA; Department of Biomedical Sciences, University of Padova, Padova, Italy.; CNR Institute of Neurosciences, Padova, Italy.
Ruzzene M; Department of Biomedical Sciences, University of Padova, Padova, Italy.; CNR Institute of Neurosciences, Padova, Italy.
Salvi M; Department of Biomedical Sciences, University of Padova, Padova, Italy.
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Źródło :
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2021 Aug; Vol. 56 (4), pp. 321-359. Date of Electronic Publication: 2021 Apr 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review; Video-Audio Media
MeSH Terms :
Signal Transduction*
Casein Kinase II/*metabolism
Neoplasm Proteins/*metabolism
Neoplasms/*enzymology
Virus Diseases/*enzymology
Animals ; Humans ; Inflammation/enzymology
Czasopismo naukowe
Tytuł :
Color Sensing and Signal Transmission Diversity of Cyanobacterial Phytochromes and Cyanobacteriochromes.
Autorzy :
Villafani Y; Department of Biological Sciences, Chungnam National University, Daejeon 34134, Korea.
Yang HW; Department of Biological Sciences, Chungnam National University, Daejeon 34134, Korea.
Park YI; Department of Biological Sciences, Chungnam National University, Daejeon 34134, Korea.
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Źródło :
Molecules and cells [Mol Cells] 2020 Jun 30; Vol. 43 (6), pp. 509-516.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Cyanobacteria/*metabolism
Phytochrome/*metabolism
Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Color ; Light Signal Transduction ; Phytochrome/chemistry
Czasopismo naukowe
Tytuł :
FBP1 enhances the radiosensitivity by suppressing glycolysis via the FBXW7/mTOR axis in nasopharyngeal carcinoma cells.
Autorzy :
Zhang P; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Shao Y; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Quan F; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Liu L; Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Yang J; Department of Oncology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 15; Vol. 283, pp. 119840. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
Glycolysis*
Radiation Tolerance*
Signal Transduction*
F-Box-WD Repeat-Containing Protein 7/*metabolism
Nasopharyngeal Carcinoma/*metabolism
Nasopharyngeal Neoplasms/*metabolism
Neoplasm Proteins/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Animals ; Cell Line, Tumor ; F-Box-WD Repeat-Containing Protein 7/genetics ; Female ; Fructose-Bisphosphatase/genetics ; Fructose-Bisphosphatase/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Middle Aged ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/pathology ; Nasopharyngeal Carcinoma/radiotherapy ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/pathology ; Nasopharyngeal Neoplasms/radiotherapy ; Neoplasm Proteins/genetics ; TOR Serine-Threonine Kinases/genetics
Czasopismo naukowe
Tytuł :
A general principle for spontaneous genetic symmetry breaking and pattern formation within cell populations.
Autorzy :
Wang X; College of Life Sciences, Zhejiang University, Hangzhou 310058, China; School of Physical Sciences, University of Science and Technology of China, Hefei 230026, China. Electronic address: .
Harrison A; Department of Mathematical Sciences, University of Essex, Colchester CO4 3SQ, UK. Electronic address: .
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Źródło :
Journal of theoretical biology [J Theor Biol] 2021 Oct 07; Vol. 526, pp. 110809. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Escherichia coli*
Signal Transduction*
Diffusion
Czasopismo naukowe
Tytuł :
Placental signaling influences cerebellum development.
Autorzy :
McCarthy MM; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland, USA. .; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2021 Oct; Vol. 24 (10), pp. 1343-1345.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Placenta*
Signal Transduction*
Cerebellum ; Female ; Humans ; Neurogenesis ; Pregnancy
Czasopismo naukowe
Tytuł :
GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii.
Autorzy :
Bhandage AK; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
Friedrich LM; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Huddinge, Sweden.
Kanatani S; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
Jakobsson-Björkén S; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Huddinge, Sweden.
Escrig-Larena JI; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Huddinge, Sweden.
Wagner AK; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
Chambers BJ; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Huddinge, Sweden.
Barragan A; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2021 Oct; Vol. 110 (4), pp. 617-628. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Killer Cells, Natural/*metabolism
Killer Cells, Natural/*parasitology
Toxoplasma/*physiology
gamma-Aminobutyric Acid/*metabolism
Animals ; Cell Death ; Cell Degranulation/physiology ; Cell Line ; Cell Movement ; Dendritic Cells/parasitology ; Humans ; Killer Cells, Natural/physiology ; Mice, Inbred C57BL ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Identification and characterization of a UbK family kinase in Porphyromonas gingivalis that phosphorylates the RprY response regulator.
Autorzy :
Perpich JD; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.; Department of Pharmaceutical Sciences, Sullivan University College of Pharmacy and Health Sciences, Louisville, Kentucky, USA.
Yakoumatos L; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
Johns P; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
Stocke KS; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
Fitzsimonds ZR; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
Wilkey DW; Division of Nephrology and Hypertension, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Merchant ML; Division of Nephrology and Hypertension, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Miller DP; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
Lamont RJ; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA.
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Źródło :
Molecular oral microbiology [Mol Oral Microbiol] 2021 Oct; Vol. 36 (5), pp. 258-266. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Porphyromonas gingivalis*/genetics
Porphyromonas gingivalis*/metabolism
Signal Transduction*
Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Phosphorylation ; Protein-Tyrosine Kinases/metabolism ; Virulence
Czasopismo naukowe
Tytuł :
Genetically encoded sensors towards imaging cAMP and PKA activity in vivo.
Autorzy :
Massengill CI; Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Day-Cooney J; Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Mao T; Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: .
Zhong H; Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: .
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2021 Oct 01; Vol. 362, pp. 109298. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Brain*/diagnostic imaging
Signal Transduction*
Animals ; Learning ; Neuronal Plasticity ; Phosphorylation
Czasopismo naukowe
Tytuł :
Intestinal interplay of quorum sensing molecules and human receptors.
Autorzy :
Krasulova K; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic. Electronic address: .
Illes P; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
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Źródło :
Biochimie [Biochimie] 2021 Oct; Vol. 189, pp. 108-119. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gastrointestinal Microbiome*
Quorum Sensing*
Signal Transduction*
Bacteria/*metabolism
Intestines/*parasitology
Humans
Czasopismo naukowe
Tytuł :
TaFDL2-1A interacts with TabZIP8-7A protein to cope with drought stress via the abscisic acid signaling pathway.
Autorzy :
Wang B; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
Li L; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
Peng; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
Liu M; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
Wei A; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
Li X; State Key Laboratory of Crop Stress Biology in Arid Areas and College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address: .
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Źródło :
Plant science : an international journal of experimental plant biology [Plant Sci] 2021 Oct; Vol. 311, pp. 111022. Date of Electronic Publication: 2021 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Droughts*
Abscisic Acid/*metabolism
Adaptation, Physiological/*genetics
Basic-Leucine Zipper Transcription Factors/*metabolism
Gene Expression Regulation, Plant/*drug effects
Signal Transduction/*genetics
Triticum/*genetics
Basic-Leucine Zipper Transcription Factors/genetics ; China ; Crops, Agricultural/genetics ; Crops, Agricultural/physiology ; Signal Transduction/physiology ; Triticum/physiology
Czasopismo naukowe
Tytuł :
Breaking boundaries: exploring short- and long-distance mitochondrial signalling in plants.
Autorzy :
Welchen E; Facultad de Bioquímica y Ciencias Biológicas, Instituto de Agrobiotecnología del Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Universidad Nacional del Litoral, Santa Fe, 3000, Argentina.
Gonzalez DH; Facultad de Bioquímica y Ciencias Biológicas, Instituto de Agrobiotecnología del Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Universidad Nacional del Litoral, Santa Fe, 3000, Argentina.
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Źródło :
The New phytologist [New Phytol] 2021 Oct; Vol. 232 (2), pp. 494-501. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Plants*
Signal Transduction*
Animals ; Mitochondria/metabolism ; Oxidation-Reduction ; Plant Development ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
New insights into BMP9 signaling in liver diseases.
Autorzy :
Jiang QQ; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Liu BB; Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Xu KS; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Oct; Vol. 476 (10), pp. 3591-3600. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Growth Differentiation Factor 2/*metabolism
Liver Diseases/*metabolism
Animals ; Humans ; Liver Diseases/pathology ; Liver Diseases/therapy
Czasopismo naukowe
Tytuł :
Inhibition of miR-1298-5p attenuates sepsis lung injury by targeting SOCS6.
Autorzy :
Ma J; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Doctor's Office, 10th floor, building 2, NO.507 Zhengmin Road, Yangpu District, Shanghai, 200433, P.R. China. .
Xu LY; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Doctor's Office, 10th floor, building 2, NO.507 Zhengmin Road, Yangpu District, Shanghai, 200433, P.R. China.
Sun QH; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Doctor's Office, 10th floor, building 2, NO.507 Zhengmin Road, Yangpu District, Shanghai, 200433, P.R. China.
Wan XY; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Doctor's Office, 10th floor, building 2, NO.507 Zhengmin Road, Yangpu District, Shanghai, 200433, P.R. China.
BingLi; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Doctor's Office, 10th floor, building 2, NO.507 Zhengmin Road, Yangpu District, Shanghai, 200433, P.R. China.
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Oct; Vol. 476 (10), pp. 3745-3756. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Acute Lung Injury/*metabolism
MicroRNAs/*metabolism
Sepsis/*metabolism
Suppressor of Cytokine Signaling Proteins/*metabolism
Acute Lung Injury/genetics ; Cell Line ; Exocytosis/genetics ; Exosomes/metabolism ; Humans ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Sepsis/genetics ; Suppressor of Cytokine Signaling Proteins/genetics
Czasopismo naukowe
Tytuł :
PHLPP1/Nrf2-Mdm2 axis induces renal apoptosis via influencing nucleo-cytoplasmic shuttling of FoxO1 during diabetic nephropathy.
Autorzy :
Mathur A; Herbal Research Laboratory, Food, Drug & Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.
Pandey VK; Herbal Research Laboratory, Food, Drug & Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, 226001, Uttar Pradesh, India.
Khan MF; Herbal Research Laboratory, Food, Drug & Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India.; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, 226001, Uttar Pradesh, India.
Kakkar P; Herbal Research Laboratory, Food, Drug & Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan 31, Mahatma Gandhi Marg, Lucknow, 226001, Uttar Pradesh, India. .; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, 226001, Uttar Pradesh, India. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Oct; Vol. 476 (10), pp. 3681-3699. Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Signal Transduction*
Diabetes Mellitus, Experimental/*metabolism
Diabetic Nephropathies/*metabolism
Kidney/*metabolism
NF-E2-Related Factor 2/*metabolism
Nerve Tissue Proteins/*metabolism
Nuclear Proteins/*metabolism
Proto-Oncogene Proteins c-mdm2/*metabolism
Animals ; Diabetes Mellitus, Experimental/pathology ; Diabetic Nephropathies/pathology ; Kidney/pathology ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe

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