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Wyszukujesz frazę ""Signal Transduction"" wg kryterium: Temat


Tytuł :
Arabidopsis FHY3 and FAR1 integrate light and strigolactone signaling to regulate branching.
Autorzy :
Xie Y; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Liu Y; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Ma M; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Zhou Q; Graduate School of Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Zhao Y; Graduate School of Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Zhao B; Graduate School of Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Wang B; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China.
Wei H; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, 510642, Guangzhou, China.
Wang H; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, 510642, Guangzhou, China. .; Guangdong Laboratory for Lingnan Modern Agriculture, 510642, Guangzhou, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Apr 23; Vol. 11 (1), pp. 1955. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Arabidopsis/*growth & development
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
Heterocyclic Compounds, 3-Ring/*metabolism
Lactones/*metabolism
Nuclear Proteins/*metabolism
Phytochrome/*metabolism
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Gene Expression Regulation, Plant ; Heterocyclic Compounds, 3-Ring/antagonists & inhibitors ; Lactones/antagonists & inhibitors ; Light ; Light Signal Transduction ; Mutation ; Nuclear Proteins/genetics ; Phytochrome/genetics ; Plants, Genetically Modified ; Promoter Regions, Genetic ; Protein Binding ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł :
Comparative transcription analysis of photosensitive and non-photosensitive eggplants to identify genes involved in dark regulated anthocyanin synthesis.
Autorzy :
He Y; School of Agriculture and Biology, Shanghai JiaoTong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.
Chen H; School of Agriculture and Biology, Shanghai JiaoTong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.
Zhou L; School of Agriculture and Biology, Shanghai JiaoTong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China.
Liu Y; School of Agriculture and Biology, Shanghai JiaoTong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China. .
Chen H; School of Agriculture and Biology, Shanghai JiaoTong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, China. .
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Źródło :
BMC genomics [BMC Genomics] 2019 Aug 28; Vol. 20 (1), pp. 678. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
MeSH Terms :
Light Signal Transduction*
Anthocyanins/*biosynthesis
Solanum melongena/*genetics
Gene Expression Regulation, Plant ; RNA-Seq ; Signal Transduction ; Solanum melongena/metabolism ; Transcription Factors/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin.
Autorzy :
Xia S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Lan Q; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Su S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Wang X; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Xu W; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Liu Z; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Zhu Y; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Wang Q; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. .
Lu L; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. .
Jiang S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2020 Jun 12; Vol. 5 (1), pp. 92. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
MeSH Terms :
Betacoronavirus/*genetics
Furin/*metabolism
SARS Virus/*genetics
Signal Transduction/*drug effects
Spike Glycoprotein, Coronavirus/*genetics
Trypsin/*metabolism
Amino Acid Motifs ; Amino Acid Sequence ; Betacoronavirus/metabolism ; Cell Line, Tumor ; Coculture Techniques ; Gene Expression Regulation ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; HEK293 Cells ; Hepatocytes/metabolism ; Hepatocytes/virology ; Host-Pathogen Interactions/genetics ; Humans ; Membrane Fusion ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism ; Proteolysis ; SARS Virus/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Signal Transduction/genetics ; Signal Transduction/immunology ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Virus Replication
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Raport
Tytuł :
Overview of lethal human coronaviruses.
Autorzy :
Chen B; Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, 610041, China.
Tian EK; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
He B; Department of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Tian L; Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, 610041, China.
Han R; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Wang S; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Xiang Q; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Zhang S; Department of Emergency Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. .
El Arnaout T; Kappa Crystals Ltd., Dublin, Ireland. .
Cheng W; Division of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, 610041, China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2020 Jun 10; Vol. 5 (1), pp. 89. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
MeSH Terms :
Pandemics*
Antiviral Agents/*therapeutic use
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Host-Pathogen Interactions/*drug effects
Pneumonia, Viral/*drug therapy
Signal Transduction/*drug effects
Betacoronavirus/genetics ; Betacoronavirus/immunology ; Betacoronavirus/pathogenicity ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Cytokines/antagonists & inhibitors ; Cytokines/genetics ; Cytokines/immunology ; Gene Expression Regulation ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Middle East Respiratory Syndrome Coronavirus/genetics ; Middle East Respiratory Syndrome Coronavirus/immunology ; Middle East Respiratory Syndrome Coronavirus/pathogenicity ; Molecular Targeted Therapy/methods ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/immunology ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; SARS Virus/drug effects ; SARS Virus/genetics ; SARS Virus/immunology ; SARS Virus/pathogenicity ; Severe Acute Respiratory Syndrome/drug therapy ; Severe Acute Respiratory Syndrome/epidemiology ; Severe Acute Respiratory Syndrome/immunology ; Severe Acute Respiratory Syndrome/virology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/virology
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
Peroxiredoxin II Inhibits Alcohol-induced Apoptosis in L02 Hepatocytes Through AKT/β-Catenin Signaling Pathway.
Autorzy :
Han YH; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Li WL; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Jin MH; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Jin YH; Library and Information Center, Library of Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Zhang YQ; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Kong LZ; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Yu LY; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China.
Hyun JW; Department of Biochemistry, School of Medicine, Jeju National University, Jeju, Republic of Korea.
Kwon J; Department of Animal Sciences, Chungbuk National University, Chungbuk, Republic of Korea .
Sun HN; College of Life Science & Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China .
Kwon T; Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea .
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Źródło :
Anticancer research [Anticancer Res] 2020 Aug; Vol. 40 (8), pp. 4491-4504.
Typ publikacji :
Journal Article
Journal Info :
Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*/drug effects
Ethanol/*adverse effects
Hepatocytes/*cytology
Peroxiredoxins/*genetics
Apoptosis ; Cell Line ; Gene Expression Regulation/drug effects ; Gene Silencing ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Phosphorylation/drug effects ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Running and swimming prevent the deregulation of the BDNF/TrkB neurotrophic signalling at the neuromuscular junction in mice with amyotrophic lateral sclerosis.
Autorzy :
Just-Borràs L; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain.
Hurtado E; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain.
Cilleros-Mañé V; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain.
Biondi O; UMR-S1124, INSERM, Faculté des Sciences Fondamentales et Biomédicales, Université Paris Descartes, 45 Rue des Saints-Pères, 75006, Paris, France.
Charbonnier F; UMR-S1124, INSERM, Faculté des Sciences Fondamentales et Biomédicales, Université Paris Descartes, 45 Rue des Saints-Pères, 75006, Paris, France.
Tomàs M; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain.
Garcia N; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain.
Tomàs J; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain. .
Lanuza MA; Unitat d'Histologia i Neurobiologia (UHNEUROB), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili. Sant Llorenç 21, 43201, Reus, Spain. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Aug; Vol. 77 (15), pp. 3027-3040. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell. Mol. Life Sci. Subsets: MEDLINE
MeSH Terms :
Physical Conditioning, Animal*
Signal Transduction*
Swimming*
Amyotrophic Lateral Sclerosis/*pathology
Neuromuscular Junction/*metabolism
Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Disease Models, Animal ; Female ; Male ; Membrane Glycoproteins/metabolism ; Mice ; Mice, Transgenic ; Motor Neurons/metabolism ; Muscle, Skeletal/metabolism ; Polymorphism, Single Nucleotide ; Protein Isoforms/metabolism ; Protein Kinase C-alpha/metabolism ; Protein-Tyrosine Kinases/metabolism ; SNARE Proteins/metabolism ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism
Czasopismo naukowe
Tytuł :
TM4SF1 involves in miR-1-3p/miR-214-5p-mediated inhibition of the migration and proliferation in keloid by regulating AKT/ERK signaling.
Autorzy :
Xu M; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Sun J; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Yu Y; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Pang Q; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Lin X; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Barakat M; Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, IL, United States.
Lei R; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Xu J; Department of Plastic Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Aug 01; Vol. 254, pp. 117746. Date of Electronic Publication: 2020 May 03.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Antigens, Surface/*physiology
Cell Movement/*physiology
Cell Proliferation/*physiology
Extracellular Signal-Regulated MAP Kinases/*metabolism
Keloid/*pathology
MicroRNAs/*metabolism
Neoplasm Proteins/*physiology
Proto-Oncogene Proteins c-akt/*metabolism
Humans ; Keloid/metabolism
Czasopismo naukowe
Tytuł :
Lymphangiogenesis induced by vascular endothelial growth factor receptor 1 signaling contributes to the progression of endometriosis in mice.
Autorzy :
Hattori K; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan; Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan.
Ito Y; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan.
Honda M; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan; Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan.
Sekiguchi K; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan; Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan.
Hosono K; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan.
Shibuya M; Gakubunkan Institute of Physiology and Medicine, Jobu University, Gunma 370-0831, Japan.
Unno N; Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan.
Majima M; Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, 252-0374, Japan; Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kanagawa, 252-0374, Japan. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Aug; Vol. 143 (4), pp. 255-263. Date of Electronic Publication: 2020 May 16.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Japanese Pharmacological Society Country of Publication: Japan NLM ID: 101167001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-8648 (Electronic) Linking ISSN: 13478613 NLM ISO Abbreviation: J. Pharmacol. Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Vascular Endothelial Growth Factor Receptor-1*
Endometriosis/*etiology
Lymphangiogenesis/*genetics
Animals ; Disease Progression ; Female ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Identification of heme oxygenase-1 from golden pompano (Trachinotus ovatus) and response of Nrf2/HO-1 signaling pathway to copper-induced oxidative stress.
Autorzy :
Xie J; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
He X; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
Fang H; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
Liao S; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
Liu Y; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
Tian L; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China.
Niu J; State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animal and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Science, Sun Yat-sen University, Guangzhou, 510275, PR China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Aug; Vol. 253, pp. 126654. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 0320657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1298 (Electronic) Linking ISSN: 00456535 NLM ISO Abbreviation: Chemosphere Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Copper/*pharmacology
Heme Oxygenase-1/*genetics
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Perciformes/*metabolism
Animals ; Antioxidants/metabolism ; Heme Oxygenase-1/metabolism ; Oxidoreductases/metabolism ; Sequence Analysis, DNA ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Antioxidant properties and neuroprotective effects of Esc-1GN through the regulation of MAPK and AKT signaling.
Autorzy :
Zeng Q; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zeng B; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Chai J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Wu J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Guo R; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Gao Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Han X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Yang J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Kotsyfakis M; Institute of Parasitology, Biology Center, Czech Academy of Sciences, Budweis, Czech Republic.
Xu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Aug 01; Vol. 254, pp. 117753. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Antioxidants/*pharmacology
Neuroprotective Agents/*pharmacology
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; MAP Kinase Signaling System ; Mice
Czasopismo naukowe
Tytuł :
An Ultradian Notch in Beta-Cell Development.
Autorzy :
Pajvani UB; From the Department of Medicine and Institute of Human Nutrition, Columbia University, New York (U.B.P.); and the Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora (L.S.).
Sussel L; From the Department of Medicine and Institute of Human Nutrition, Columbia University, New York (U.B.P.); and the Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora (L.S.).
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Źródło :
The New England journal of medicine [N Engl J Med] 2020 Jul 02; Vol. 383 (1), pp. 80-82.
Typ publikacji :
Journal Article; Comment
Journal Info :
Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N. Engl. J. Med. Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Organogenesis*
Signal Transduction*
Cell Differentiation ; Pancreas
Czasopismo naukowe
Tytuł :
Combination of CD47 and signal-regulatory protein-α constituting the "don't eat me signal" is a prognostic factor in diffuse large B-cell lymphoma.
Autorzy :
Kazama R; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.; Department of Internal Medicine, Sakai City Medical Center, Sakai, Japan.
Miyoshi H; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Takeuchi M; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Miyawaki K; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Nakashima K; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Yoshida N; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.; Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan.
Kawamoto K; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Yanagida E; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Yamada K; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Umeno T; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Suzuki T; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Kato K; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Takizawa J; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Seto M; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
Akashi K; Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Ohshima K; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2608-2619. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Antigens, Differentiation/*metabolism
CD47 Antigen/*metabolism
Lymphoma, Large B-Cell, Diffuse/*metabolism
Lymphoma, Large B-Cell, Diffuse/*mortality
Receptors, Immunologic/*metabolism
Adult ; Aged ; Aged, 80 and over ; Antigens, Differentiation/genetics ; Antineoplastic Combined Chemotherapy Protocols ; Biomarkers ; CD47 Antigen/genetics ; Cyclophosphamide ; Doxorubicin ; Female ; Gene Expression ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large B-Cell, Diffuse/therapy ; Middle Aged ; Prednisone ; Prognosis ; Receptors, Immunologic/genetics ; Rituximab ; Treatment Outcome ; Vincristine
Czasopismo naukowe
Tytuł :
Extensive signal integration by the phytohormone protein network.
Autorzy :
Altmann M; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Altmann S; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Rodriguez PA; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Weller B; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Elorduy Vergara L; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Palme J; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Marín-de la Rosa N; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Sauer M; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Wenig M; Inducible Resistance Signaling Group, Institute of Biochemical Plant Pathology (BIOP), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Villaécija-Aguilar JA; Plant Genetics, TUM School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.
Sales J; Inducible Resistance Signaling Group, Institute of Biochemical Plant Pathology (BIOP), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Lin CW; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Pandiarajan R; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Young V; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Strobel A; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Gross L; Botany, TUM School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.
Carbonnel S; Genetics, Faculty of Biology, Ludwig-Maximilians-Universität (LMU) München, Planegg-Martinsried, Germany.
Kugler KG; Plant Genome and Systems Biology (PGSB), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Garcia-Molina A; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; Plant Molecular Biology, Faculty of Biology, Ludwig-Maximilians-Universität (LMU) München, Planegg-Martinsried, Germany.
Bassel GW; School of Biosciences, University of Birmingham, Birmingham, UK.
Falter C; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Mayer KFX; Plant Genome and Systems Biology (PGSB), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; TUM School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.
Gutjahr C; Plant Genetics, TUM School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.; Genetics, Faculty of Biology, Ludwig-Maximilians-Universität (LMU) München, Planegg-Martinsried, Germany.
Vlot AC; Inducible Resistance Signaling Group, Institute of Biochemical Plant Pathology (BIOP), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Grill E; Botany, TUM School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.
Falter-Braun P; Institute of Network Biology (INET), Helmholtz Center Munich, German Research Center for Environmental Health, Munich-Neuherberg, Germany. .; Microbe-Host Interactions, Faculty of Biology, Ludwig-Maximilians-Universität (LMU) München, Planegg-Martinsried, Germany. .
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Źródło :
Nature [Nature] 2020 Jul; Vol. 583 (7815), pp. 271-276. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
MeSH Terms :
Protein Interaction Maps*
Signal Transduction*
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
Plant Growth Regulators/*metabolism
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Protein Binding ; Protein Interaction Mapping ; Reproducibility of Results ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Multiple N-glycans cooperate in balancing misfolded BRI1 secretion and ER retention.
Autorzy :
Chen T; State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210046, Jiangsu, China.
Zhang H; State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210046, Jiangsu, China.
Niu G; State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210046, Jiangsu, China.
Zhang S; State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210046, Jiangsu, China.
Hong Z; State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing, 210046, Jiangsu, China. .
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Źródło :
Plant molecular biology [Plant Mol Biol] 2020 Jul; Vol. 103 (4-5), pp. 581-596. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 9106343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-5028 (Electronic) Linking ISSN: 01674412 NLM ISO Abbreviation: Plant Mol. Biol. Subsets: MEDLINE
MeSH Terms :
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
Endoplasmic Reticulum/*metabolism
Polysaccharides/*metabolism
Protein Kinases/*metabolism
Signal Transduction/*physiology
Alkaloids/metabolism ; Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Glycoproteins/metabolism ; Glycoside Hydrolases/metabolism ; Glycosylation ; Models, Molecular ; Oligosaccharides/metabolism ; Plants, Genetically Modified ; Protein Conformation ; Protein Domains ; Protein Processing, Post-Translational ; Seedlings ; Seeds/cytology ; Seeds/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Potential role of transforming growth factor-beta 1/Smad signaling in secondary lymphedema after cancer surgery.
Autorzy :
Sano M; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Hirakawa S; Institute for NanoSuit Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Suzuki M; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Sakabe JI; Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore.
Ogawa M; Faculty of Pharmaceutical Sciences Biopharmaceutical Sciences and Pharmacy, Hokkaido University, Sapporo, Japan.
Yamamoto S; Department of Innovative Medical Photonics, Applied Medical Photonics Laboratory, Medical Photonics Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Hiraide T; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Sasaki T; Department of Anatomy and Neuroscience, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yamamoto N; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Inuzuka K; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Tanaka H; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Department of Medical Physiology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Saito T; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Sugisawa R; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Katahashi K; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yata T; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Kayama T; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Urano T; Department of Medical Physiology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Tokura Y; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Sato K; Department of Anatomy and Neuroscience, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Setou M; Department of Systems Molecular Anatomy, Basic Medical Photonics Laboratory, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Takeuchi H; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Konno H; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Unno N; Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.; Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2620-2634. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Postoperative Complications*
Signal Transduction*
Lymphedema/*etiology
Lymphedema/*metabolism
Smad Proteins/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Biomarkers ; Disease Models, Animal ; Fibroblasts/metabolism ; Fibrosis ; Humans ; Immunohistochemistry ; Lymphatic Vessels/metabolism ; Lymphatic Vessels/pathology ; Lymphedema/diagnostic imaging ; Lymphedema/pathology ; Macrophages/metabolism ; Macrophages/pathology ; Rats ; Severity of Illness Index ; Skin/metabolism ; Skin/pathology ; Transforming Growth Factor beta1/genetics
Czasopismo naukowe
Tytuł :
Squalene epoxidase-induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling.
Autorzy :
Li L; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
Zhang Q; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
Wang X; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
Li Y; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
Xie H; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
Chen X; Department of Otolaryngology Head and Neck Surgery, Shenzhen University General Hospital, Shenzhen, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2275-2283. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Cholesterol Esters/*metabolism
Nasopharyngeal Carcinoma/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Squalene Monooxygenase/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/genetics ; Biomarkers, Tumor ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation, Neoplastic ; Humans ; Mice, Nude ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/mortality ; Nasopharyngeal Carcinoma/pathology ; Prognosis ; Squalene Monooxygenase/antagonists & inhibitors ; Squalene Monooxygenase/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling.
Autorzy :
Wang L; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Ai M; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Nie M; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhao L; Department of Pathology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Deng G; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Hu S; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Han Y; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zeng W; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wang Y; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Yang M; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wang S; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2310-2324. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Signal Transduction*
Transcriptional Activation*
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*metabolism
Transcription Factors/*metabolism
Transforming Growth Factor beta1/*genetics
Transforming Growth Factor beta1/*metabolism
Adult ; Aged ; Animals ; Biomarkers, Tumor ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; Disease Models, Animal ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Heterografts ; Humans ; Immunohistochemistry ; Male ; Mice ; Middle Aged ; Models, Biological ; Neoplasm Metastasis ; Neoplasm Staging ; Protein Transport ; Transcription Factors/genetics ; Tumor Burden
Czasopismo naukowe
Tytuł :
Dysregulation in nucleic acid-sensing pathway genes is associated with cancer patients' prognosis.
Autorzy :
Yan-Fei H; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Han Y; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Yan-Ting Z; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Hui Y; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Yu-Qing Y; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Ipsita P; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Hui-Ying H; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Wei-Gang F; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
Xin-Xia T; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2212-2222. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Immunity, Innate*
Signal Transduction*
Neoplasms/*etiology
Neoplasms/*metabolism
Nucleic Acids/*immunology
Nucleic Acids/*metabolism
Biomarkers ; Cluster Analysis ; Computational Biology/methods ; DNA Methylation ; Gene Expression Profiling ; Humans ; Kaplan-Meier Estimate ; Neoplasms/mortality ; Prognosis
Czasopismo naukowe
Tytuł :
Molecular pathways in vulvar squamous cell carcinoma: implications for target therapeutic strategies.
Autorzy :
Giulia Mantovani; Dipartimento di Ginecologia e Ostetricia, Ginecologia Oncologica e Chirurgia Pelvica Mini-Invasiva, International School of Surgical Anatomy, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
Fragomeni SM; Unità di Ginecologia Oncologica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy. .
Inzani F; Unità di Gineco-Patologia e Patologia Mammaria, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Fagotti A; Unità di Ginecologia Oncologica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.; Istituto di Clinica Ostetrica e Ginecologica, Università Cattolica del Sacro Cuore, Rome, Italy.
Della Corte L; Dipartimento di Neuroscienze e Scienze Riproduttive ed Odontostomatologiche, Scuola di Medicina e Chirurgia, Università degli studi di Napoli Federico II, Naples, Italy.
Gentileschi S; Unità di Chirurgia Plastica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Istituto di Clinica Chirurgica, Università Cattolica del Sacro Cuore, Rome, Italy.
Tagliaferri L; Unità Operativa Complessa di Radioterapia, Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Zannoni GF; Unità di Gineco-Patologia e Patologia Mammaria, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Istituto di Anatomia Patologica, Università Cattolica del Sacro Cuore, Rome, Italy.
Scambia G; Unità di Ginecologia Oncologica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.; Istituto di Clinica Ostetrica e Ginecologica, Università Cattolica del Sacro Cuore, Rome, Italy.
Garganese G; Unità di Ginecologia Oncologica, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.; Gynecology and Breast Care Center, Mater Olbia Hospital, Olbia, Italy.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2020 Jul; Vol. 146 (7), pp. 1647-1658. Date of Electronic Publication: 2020 Apr 25.
Typ publikacji :
Journal Article; Meta-Analysis; Review
Journal Info :
Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1335 (Electronic) Linking ISSN: 01715216 NLM ISO Abbreviation: J. Cancer Res. Clin. Oncol. Subsets: MEDLINE
MeSH Terms :
Biomarkers, Tumor*
Gene Expression Regulation, Neoplastic*
Signal Transduction*
Carcinoma, Squamous Cell/*etiology
Carcinoma, Squamous Cell/*metabolism
Vulvar Neoplasms/*etiology
Vulvar Neoplasms/*metabolism
Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/pathology ; Cell Cycle/genetics ; Clinical Decision-Making ; Disease Susceptibility ; Extracellular Space/metabolism ; Female ; Humans ; Intracellular Space/metabolism ; Molecular Targeted Therapy ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/immunology ; Neovascularization, Pathologic/metabolism ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology ; Vulvar Neoplasms/drug therapy ; Vulvar Neoplasms/pathology
Czasopismo naukowe
Tytuł :
TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation.
Autorzy :
Yoshimatsu Y; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.; Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Wakabayashi I; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Kimuro S; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Takahashi N; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Takahashi K; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Kobayashi M; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Maishi N; Department of Vascular Biology and Molecular Pathology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Podyma-Inoue KA; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Hida K; Department of Vascular Biology and Molecular Pathology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Miyazono K; Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Watabe T; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2385-2399. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci. Subsets: MEDLINE
MeSH Terms :
Epithelial-Mesenchymal Transition*/drug effects
Signal Transduction*/drug effects
Transforming Growth Factor beta/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Biomarkers ; Cancer-Associated Fibroblasts/metabolism ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Cell Line ; Cells, Cultured ; Endothelial Cells/metabolism ; Humans ; Inflammation Mediators/metabolism ; Mouth Neoplasms/drug therapy ; Mouth Neoplasms/genetics ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; NF-kappa B/metabolism ; Receptor, Transforming Growth Factor-beta Type I ; Smad2 Protein/metabolism ; Smad3 Protein/metabolism ; Transforming Growth Factor beta/pharmacology ; Tumor Microenvironment/genetics ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe

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