Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Signal Transduction drug effects"" wg kryterium: Temat


Tytuł :
Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma:Increased Cell Migration and Its Association with EGFR Expression
Autorzy :
Molnár, Eszter
Garay, Tamás
Donia, Marco
Baranyi, Marcell
Rittler, Dominika
Berger, Walter
Tímár, József
Grusch, Michael
Hegedűs, Balázs
Pokaż więcej
Temat :
Adult
Aged
Cell Line, Tumor
Cell Movement/drug effects
Cell Proliferation/drug effects
Drug Resistance, Neoplasm/drug effects
Epithelial-Mesenchymal Transition/drug effects
ErbB Receptors/metabolism
Erlotinib Hydrochloride/pharmacology
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Inhibitory Concentration 50
Male
Melanoma/drug therapy
Middle Aged
Mutation/genetics
Neoplasm Proteins/genetics
Phenotype
Proto-Oncogene Proteins B-raf/genetics
RNA, Messenger/genetics
Signal Transduction/drug effects
Time Factors
Vemurafenib/pharmacology
Journal Article
Źródło :
Molnár, E, Garay, T, Donia, M, Baranyi, M, Rittler, D, Berger, W, Tímár, J, Grusch, M & Hegedűs, B 2019, ' Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma : Increased Cell Migration and Its Association with EGFR Expression ', International Journal of Molecular Sciences, vol. 20, no. 18, 4484 . https://doi.org/10.3390/ijms20184484
Opis pliku :
application/pdf
Tytuł :
Signaling mediators modulated by cardioprotective interventions in healthy and diabetic myocardium with ischaemia–reperfusion injury
Autorzy :
Saeid, Feyzizadeh
Aniseh, Javadi
Reza, Badalzadeh
Manouchehr, Vafaee S.
Pokaż więcej
Temat :
Cardioprotection
diabetes
ischaemia–reperfusion injury
ischaemic postconditioning
ischaemic preconditioning
remote ischaemic conditioning
Diabetic Cardiomyopathies/metabolism
Myocardial Reperfusion Injury/metabolism
Cardiovascular Agents/therapeutic use
Humans
Risk Factors
Treatment Outcome
Signal Transduction/drug effects
Animals
Ischemic Preconditioning, Myocardial
Myocardium/metabolism
Ischemic Postconditioning
Źródło :
Saeid, F, Aniseh, J, Reza, B & Manouchehr, V S 2018, ' Signaling mediators modulated by cardioprotective interventions in healthy and diabetic myocardium with ischaemia–reperfusion injury ', European Journal of Preventive Cardiology, vol. 25, no. 14, pp. 1463-1481 . https://doi.org/10.1177/2047487318756420
Tytuł :
A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission
Autorzy :
Audouze, Karine
Taboureau, Olivier
Grandjean, Philippe
Pokaż więcej
Temat :
Systems biology
Computational biology
Zika Virus/pathogenicity
Risk Assessment
Insecticides/adverse effects
Predictive toxicology
Culicidae/drug effects
Pyridines/adverse effects
Microcephaly/chemically induced
Signal Transduction/drug effects
Zika Virus Infection/prevention & control
Animals
Systems Biology/methods
Insect Vectors
Pesticide
Neurotoxicity Syndromes/etiology
Larva/drug effects
Toxicity testing
Mosquito Control/methods
Developmental neurotoxicity
Article
Journal Article
Toxicity Tests
Protein Interaction Maps/drug effects
Humans
Pyriproxyfen
Źródło :
Audouze, K, Taboureau, O & Grandjean, P 2018, ' A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission ', Toxicology and Applied Pharmacology, vol. 354, pp. 56-63 . https://doi.org/10.1016/j.taap.2018.02.014
Opis pliku :
application/pdf
Tytuł :
Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity
Autorzy :
Ek, Sara
Freiburghaus, Catja
Emruli, Venera Kuci
Johansson, Angelica
Eskelund, Christian Winther
Grønbæk, Kirsten
Olsson, Roger
Ek, Fredrik
Jerkeman, Mats
Pokaż więcej
Temat :
Cytarabine
Research Article
SPIB
Gene Expression Regulation, Neoplastic/drug effects
Lymphoma, Mantle-Cell/genetics
DCK
Research Support, Non-U.S. Gov't
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Histone Deacetylase Inhibitors/pharmacology
Signal Transduction/drug effects
Deoxycytidine Kinase/genetics
MCL
Transcription Factors/genetics
Bortezomib/pharmacology
Cytarabine/pharmacology
Dose-Response Relationship, Drug
Transcription, Genetic
NF-κB
Drug Resistance, Neoplasm/drug effects
Antineoplastic Agents/pharmacology
DNA-Binding Proteins/genetics
NF-kappa B/metabolism
Cell Line, Tumor
RC254-282
Journal Article
Gene Expression Profiling
Humans
Źródło :
BMC Cancer, Vol 18, Iss 1, Pp 1-17 (2018)
Freiburghaus, C, Emruli, V K, Johansson, A, Eskelund, C W, Grønbæk, K, Olsson, R, Ek, F, Jerkeman, M & Ek, S 2018, ' Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity ', BMC Cancer, vol. 18, no. 1, 466 . https://doi.org/10.1186/s12885-018-4346-1
Opis pliku :
application/pdf
Tytuł :
Muscle α-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients
Autorzy :
Iepsen, Ulrik Winning
Munch, Gregers Druedal Wibe
Ryrsø, Camilla Koch
Secher, Niels H.
Lange, Peter
Thaning, Pia
Pedersen, Bente Klarlund
Mortensen, Stefan P.
Pokaż więcej
Temat :
Vasoconstriction/drug effects
Vasodilation/drug effects
Vasodilator Agents/administration & dosage
Functional sympatholysis
Tyramine/administration & dosage
Infusions, Intra-Arterial
Quadriceps Muscle/blood supply
Aged
Exercise
Middle Aged
Lower Extremity/blood supply
Signal Transduction/drug effects
Sympathomimetics/administration & dosage
Regional Blood Flow
Adenosine Triphosphate/administration & dosage
Leg blood flow
Receptors, Adrenergic, alpha/metabolism
Female
Humans
Pulmonary Disease, Chronic Obstructive/diagnosis
Femoral Artery/drug effects
Male
Case-Control Studies
Źródło :
Iepsen, U W, Munch, G D W, Ryrsø, C K, Secher, N H, Lange, P, Thaning, P, Pedersen, B K & Mortensen, S P 2018, ' Muscle α-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients ', American Journal of Physiology: Heart and Circulatory Physiology, vol. 314, no. 2, pp. H180-H187 . https://doi.org/10.1152/ajpheart.00398.2017
Opis pliku :
application/pdf
Tytuł :
N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake
Autorzy :
Dreisig, Karin
Kristensen, Nikolaj Pagh
Dommer, Maja Wallentin
Jørgensen, Niklas Rye
Kornum, Birgitte Rahbek
Pokaż więcej
Temat :
Receptors, Purinergic P2X7/metabolism
Original Article
Signal Transduction/drug effects
Fluo4
Purinergic
Green Fluorescent Proteins/pharmacology
Fluorescent Dyes/pharmacology
Calcium Channels/metabolism
Flow cytometry
ATP
Humans
Źródło :
Dreisig, K, Kristensen, N P, Dommer, M W, Jørgensen, N R & Kornum, B R 2018, ' N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake ', Purinergic Signalling, vol. 14, no. 1, pp. 83–90 . https://doi.org/10.1007/s11302-017-9598-8
Opis pliku :
application/pdf

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies