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Wyszukujesz frazę ""Signal Transduction genetics"" wg kryterium: Temat


Tytuł :
Establishment of porcine and human expanded potential stem cells.
Autorzy :
Gao, Xuefei
Nowak-Imialek, Monika
Chen, Xi
Chen, Dongsheng
Herrmann, Doris
Ruan, Degong
Chen, Andy Chun Hang
Eckersley-Maslin, Melanie A
Ahmad, Shakil
Lee, Yin Lau
Kobayashi, Toshihiro
Ryan, David
Zhong, Jixing
Zhu, Jiacheng
Wu, Jian
Lan, Guocheng
Petkov, Stoyan
Yang, Jian
Antunes, Liliana
Campos, Lia S
Fu, Beiyuan
Wang, Shengpeng
Yong, Yu
Wang, Xiaomin
Xue, Song-Guo
Ge, Liangpeng
Liu, Zuohua
Huang, Yong
Nie, Tao
Li, Peng
Wu, Donghai
Pei, Duanqing
Zhang, Yi
Lu, Liming
Yang, Fengtang
Kimber, Susan J
Reik, Wolf
Zou, Xiangang
Shang, Zhouchun
Lai, Liangxue
Surani, Azim
Tam, Patrick P L
Ahmed, Asif
Yeung, William Shu Biu
Teichmann, Sarah A
Niemann, Heiner
Liu, Pentao
Pokaż więcej
Temat :
Cellular Reprogramming/genetics
Cell Differentiation
Pluripotent Stem Cells
Regenerative Medicine
Embryonic Stem Cells
Cell Lineage/genetics
Mice
Germ Layers
Induced Pluripotent Stem Cells/cytology
Blastomeres/cytology
Embryonic Stem Cells/cytology
Animals
Signal Transduction
Signal Transduction/genetics
Trophoblasts
Cellular Reprogramming
Cell Differentiation/genetics
musculoskeletal, neural, and ocular physiology
Swine
nervous system
Cell Lineage
Blastomeres
Trophoblasts/cytology
Induced Pluripotent Stem Cells
Humans
Germ Layers/growth & development
Pluripotent Stem Cells/cytology
Źródło :
Gao, X, Nowak-Imialek, M, Chen, X, Chen, D, Herrmann, D, Ruan, D, Chen, A C H, Eckersley-Maslin, M A, Ahmad, S, Lee, Y L, Kobayashi, T, Ryan, D, Zhong, J, Zhu, J, Wu, J, Lan, G, Petkov, S, Yang, J, Antunes, L, Campos, L S, Fu, B, Wang, S, Yong, Y, Wang, X, Xue, S-G, Ge, L, Liu, Z, Huang, Y, Nie, T, Li, P, Wu, D, Pei, D, Zhang, Y, Lu, L, Yang, F, Kimber, S J, Reik, W, Zou, X, Shang, Z, Lai, L, Surani, A, Tam, P P L, Ahmed, A, Yeung, W S B, Teichmann, S A, Niemann, H & Liu, P 2019, ' Establishment of porcine and human expanded potential stem cells ', Nature Cell Biology, vol. 21, no. 6, pp. 687-699 . https://doi.org/10.1038/s41556-019-0333-2
Opis pliku :
application/pdf; Print-Electronic
Tytuł :
The landscape of epilepsy-related GATOR1 variants
Autorzy :
Baldassari, Sara
Picard, Fabienne
Verbeek, Nienke E.
van Kempen, Marjan
Brilstra, Eva H.
Lesca, Gaetan
Conti, Valerio
Guerrini, Renzo
Bisulli, Francesca
Licchetta, Laura
Pippucci, Tommaso
Tinuper, Paolo
Hirsch, Edouard
de Saint Martin, Anne
Chelly, Jamel
Rudolf, Gabrielle
Chipaux, Mathilde
Ferrand-Sorbets, Sarah
Dorfmüller, Georg
Sisodiya, Sanjay
Balestrini, Simona
Schoeler, Natasha
Hernandez-Hernandez, Laura
Krithika, S.
Oegema, Renske
Hagebeuk, Eveline
Gunning, Boudewijn
Deckers, Charles
Berghuis, Bianca
Wegner, Ilse
Niks, Erik
Jansen, Floor E.
Braun, Kees
de Jong, Daniëlle
Rubboli, Guido
Talvik, Inga
Sander, Valentin
Uldall, Peter
Jacquemont, Marie-Line
Nava, Caroline
Leguern, Eric
Julia, Sophie
Gambardella, Antonio
d’Orsi, Giuseppe
Crichiutti, Giovanni
Faivre, Laurence
Darmency, Veronique
Benova, Barbora
Krsek, Pavel
Biraben, Arnaud
Lebre, Anne-Sophie
Jennesson, Mélanie
Sattar, Shifteh
Marchal, Cécile
Nordli, Douglas R
Lindstrom, Kristin
Striano, Pasquale
Lomax, Lysa Boissé
Kiss, Courtney
Bartolomei, Fabrice
Lepine, Anne Fabienne
Schoonjans, An-Sofie
Stouffs, Katrien
Jansen, Anna
Panagiotakaki, Eleni
Ricard-Mousnier, Brigitte
Thevenon, Julien
de Bellescize, Julitta
Catenoix, Hélène
Dorn, Thomas
Zenker, Martin
Müller-Schlüter, Karen
Brandt, Christian
Krey, Ilona
Polster, Tilman
Wolff, Markus
Balci, Meral
Rostasy, Kevin
Achaz, Guillaume
Zacher, Pia
Becher, Thomas
Cloppenborg, Thomas
Yuskaitis, Christopher J.
Weckhuysen, Sarah
Poduri, Annapurna
Lemke, Johannes R.
Møller, Rikke S.
Baulac, Stéphanie
Pokaż więcej
Temat :
Epilepsy
Seizures/complications
INDEL Mutation
Infant, Newborn
Brugada Syndrome/genetics
ddc:616.8
Infant
Research Support, Non-U.S. Gov't
DEPDC5
GTPase-Activating Proteins/genetics
Epilepsy/complications
Tumor Suppressor Proteins
Loss of Function Mutation
Genetic focal epilepsy
Brugada Syndrome
Seizures
Multiprotein Complexes
Female
GTPase-Activating Proteins
Child, Preschool
Repressor Proteins
INDEL Mutation/genetics
Signal Transduction
SUDEP
Signal Transduction/genetics
mTORC1 pathway
Loss of Function Mutation/genetics
Multiprotein Complexes/genetics
Tumor Suppressor Proteins/genetics
DNA Copy Number Variations/genetics
[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics
Article
Pedigree
Focal cortical dysplasia
Mechanistic Target of Rapamycin Complex 1
Repressor Proteins/genetics
DNA Copy Number Variations
Adolescent
Journal Article
Genetic Predisposition to Disease
Mechanistic Target of Rapamycin Complex 1/genetics
Humans
Human medicine
Male
Child
Źródło :
Genetics in Medicine, Nature Publishing Group, 2019, 21 (2), pp.398-408. ⟨10.1038/s41436-018-0060-2⟩
Genetics in Medicine (2018)
Genetics in medicine : official journal of the American College of Medical Genetics
Baldassari, S, Picard, F, Verbeek, N E, van Kempen, M, Brilstra, E H, Lesca, G, Conti, V, Guerrini, R, Bisulli, F, Licchetta, L, Pippucci, T, Tinuper, P, Hirsch, E, de Saint Martin, A, Chelly, J, Rudolf, G, Chipaux, M, Ferrand-Sorbets, S, Dorfmüller, G, Sisodiya, S, Balestrini, S, Schoeler, N, Hernandez-Hernandez, L, Krithika, S, Oegema, R, Hagebeuk, E, Gunning, B, Deckers, C, Berghuis, B, Wegner, I, Niks, E, Jansen, F E, Braun, K, de Jong, D, Rubboli, G, Talvik, I, Sander, V, Uldall, P, Jacquemont, M-L, Nava, C, Leguern, E, Julia, S, Gambardella, A, d'Orsi, G, Crichiutti, G, Faivre, L, Darmency, V, Benova, B, Krsek, P, Biraben, A, Lebre, A-S, Jennesson, M, Sattar, S, Marchal, C, Nordli, D R, Lindstrom, K, Striano, P, Lomax, L B, Kiss, C, Bartolomei, F, Lepine, A F, Schoonjans, A-S, Stouffs, K, Jansen, A, Panagiotakaki, E, Ricard-Mousnier, B, Thevenon, J, de Bellescize, J, Catenoix, H, Dorn, T, Zenker, M, Müller-Schlüter, K, Brandt, C, Krey, I, Polster, T, Wolff, M, Balci, M, Rostasy, K, Achaz, G, Zacher, P, Becher, T, Cloppenborg, T, Yuskaitis, C J, Weckhuysen, S, Poduri, A, Lemke, J R, Møller, R S & Baulac, S 2019, ' The landscape of epilepsy-related GATOR1 variants ', Genetics In Medicine, vol. 21, no. 2, pp. 398-408 . https://doi.org/10.1038/s41436-018-0060-2
Baldassari, S, Picard, F, Verbeek, N E, van Kempen, M, Brilstra, E H, Lesca, G, Conti, V, Guerrini, R, Bisulli, F, Licchetta, L, Pippucci, T, Tinuper, P, Hirsch, E, de Saint Martin, A, Chelly, J, Rudolf, G, Chipaux, M, Ferrand-Sorbets, S, Dorfmüller, G, Sisodiya, S, Balestrini, S, Schoeler, N, Hernandez-Hernandez, L, Krithika, S, Oegema, R, Hagebeuk, E, Gunning, B, Deckers, C, Berghuis, B, Wegner, I, Niks, E, Jansen, F E, Braun, K, de Jong, D, Rubboli, G, Talvik, I, Sander, V, Uldall, P, Jacquemont, M L, Nava, C, Leguern, E, Julia, S, Gambardella, A, d’Orsi, G, Crichiutti, G, Faivre, L, Darmency, V, Benova, B, Krsek, P, Biraben, A, Lebre, A S, Jennesson, M, Sattar, S, Marchal, C, Nordli, D R, Lindstrom, K, Striano, P, Lomax, L B, Kiss, C, Bartolomei, F, Lepine, A F, Schoonjans, A S, Stouffs, K, Jansen, A, Panagiotakaki, E, Ricard-Mousnier, B, Thevenon, J, de Bellescize, J, Catenoix, H, Dorn, T, Zenker, M, Müller-Schlüter, K, Brandt, C, Krey, I, Polster, T, Wolff, M, Balci, M, Rostasy, K, Achaz, G, Zacher, P, Becher, T, Cloppenborg, T, Yuskaitis, C J, Weckhuysen, S, Poduri, A, Lemke, J R, Møller, R S & Baulac, S 2019, ' The landscape of epilepsy-related GATOR1 variants ', Genetics in Medicine, vol. 21, no. 2, pp. 398-408 . https://doi.org/10.1038/s41436-018-0060-2
Opis pliku :
application/pdf; pdf; STAMPA
Tytuł :
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.
Autorzy :
Timmers, P.R.
Mounier, N.
Lall, K.
Fischer, K.
Ning, Z.
Feng, X.
Bretherick, A.D.
Clark, D.W.
Agbessi, M.
Ahsan, H.
Alves, I.
Andiappan, A.
Awadalla, P.
Battle, A.
Bonder, M.J.
Boomsma, D.
Christiansen, M.
Claringbould, A.
Deelen, P.
van Dongen, J.
Esko, T.
Favé, M.
Franke, L.
Frayling, T.
Gharib, S.A.
Gibson, G.
Hemani, G.
Jansen, R.
Kalnapenkis, A.
Kasela, S.
Kettunen, J.
Kim, Y.
Kirsten, H.
Kovacs, P.
Krohn, K.
Kronberg-Guzman, J.
Kukushkina, V.
Kutalik, Z.
Kähönen, M.
Lee, B.
Lehtimäki, T.
Loeffler, M.
Marigorta, U.
Metspalu, A.
van Meurs, J.
Milani, L.
Müller-Nurasyid, M.
Nauck, M.
Nivard, M.
Penninx, B.
Perola, M.
Pervjakova, N.
Pierce, B.
Powell, J.
Prokisch, H.
Psaty, B.M.
Raitakari, O.
Ring, S.
Ripatti, S.
Rotzschke, O.
Ruëger, S.
Saha, A.
Scholz, M.
Schramm, K.
Seppälä, I.
Stumvoll, M.
Sullivan, P.
Teumer, A.
Thiery, J.
Tong, L.
Tönjes, A.
Verlouw, J.
Visscher, P.M.
Võsa, U.
Völker, U.
Yaghootkar, H.
Yang, J.
Zeng, B.
Zhang, F.
Shen, X.
Wilson, J.F.
Joshi, P.K.
Pokaż więcej
Temat :
Age Factors
Aged
Bayes Theorem
DNA Methylation/genetics
Disease/genetics
Female
Genetic Loci
Genome-Wide Association Study
Genomics
Humans
Longevity/genetics
Male
Middle Aged
Multifactorial Inheritance/genetics
Parents
Polymorphism, Single Nucleotide/genetics
Risk Factors
Sex Characteristics
Signal Transduction/genetics
Survival Analysis
complex trait
genetics
genomics
human
lifespan
longevity
Źródło :
eLife, vol. 8, pp. e39856
Opis pliku :
application/pdf
Tytuł :
miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC
Autorzy :
Kim, Taewan
Rhee, Siyeon
Kim, Yonghwan
Jeon, Young-Jun
Park, Dongju
Nuovo, Gerard J.
Joshi, Pooja
Lee, Bum-Kyu
Jeong, Johan
Suh, Sung-suk
Grotzke, Jeff E.
Kim, Sung-Hak
Song, Jieun
Sim, Hosung
Peng, Yong
Jeong, Youngtae
Garofalo, Michela
Zanesi, Nicola
Kim, Jonghwan
Liang, Guang
Nakano, Ichiro
Cresswell, Peter
Nana-Sinkam, Patrick
Cui, Ri
Croce, Carlo M.
Pokaż więcej
Temat :
Lung Neoplasms/genetics
Carcinoma, Non-Small-Cell Lung/genetics
Endoribonucleases/genetics
Signal Transduction/genetics
Cell Proliferation/genetics
Gene Expression Regulation, Neoplastic/genetics
Tumor Suppressor Proteins/genetics
Mice
Article
Cell Line, Tumor
Ubiquitin-Protein Ligases/genetics
Activating Transcription Factor 6/genetics
Unfolded Protein Response/genetics
Science
Endoplasmic Reticulum-Associated Degradation/genetics
Reverse Transcriptase Polymerase Chain Reaction
Animals
MicroRNAs/metabolism
Xenograft Model Antitumor Assays
Tumor Suppressor Protein p53/genetics
Humans
Membrane Proteins/genetics
In Situ Hybridization
Źródło :
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Jeon, Y-J, Kim, T, Park, D, Nuovo, G J, Rhee, S, Joshi, P, Lee, B-K, Jeong, J, Suh, S-S, Grotzke, J E, Kim, S-H, Song, J, Sim, H, Kim, Y, Peng, Y, Jeong, Y, Garofalo, M, Zanesi, N, Kim, J, Liang, G, Nakano, I, Cresswell, P, Nana-Sinkam, P, Cui, R & Croce, C M 2018, ' miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC ', Nature Communications, vol. 9, no. 1, pp. 5110 . https://doi.org/10.1038/s41467-018-07561-8
Tytuł :
Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer
Autorzy :
Chong, Irene Yushing
Aronson, Lauren
Bryant, Hanna
Gulati, Aditi
Campbell, James
Elliott, Richard
Pettitt, Stephen
Wilkerson, Paul
Lambros, Maryou B
Reis-Filho, Jorge S
Ramessur, Anisha
Davidson, Michael
Chau, Ian
Cunningham, David
Ashworth, Alan
Lord, Christopher J
Pokaż więcej
Temat :
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Drug Discovery/methods
Esophageal Neoplasms/drug therapy
Humans
Pharmacogenetics
Pharmacogenomic Testing/methods
Proto-Oncogene Proteins c-myc/genetics
Pyrazoles/pharmacology
Pyrimidines/pharmacology
RNA Interference/drug effects
Receptor, ErbB-2/genetics
Signal Transduction/genetics
Xenograft Model Antitumor Assays
Źródło :
Chong, I Y, Aronson, L, Bryant, H, Gulati, A, Campbell, J, Elliott, R, Pettitt, S, Wilkerson, P, Lambros, M B, Reis-Filho, J S, Ramessur, A, Davidson, M, Chau, I, Cunningham, D, Ashworth, A & Lord, C J 2018, ' Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer ', Gut, vol. 67, no. 10, pp. 1780-1792 . https://doi.org/10.1136/gutjnl-2017-314408
Opis pliku :
application/pdf
Tytuł :
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis
Autorzy :
Zakaria, Chadi
Sean, Polen
Hoang, Huy-Dung
Leroux, Louis-Phillipe
Watson, Margaret
Workenhe, Samuel Tekeste
Hearnden, Jaclyn
Pearl, Dana
Truong, Vinh Tai
Robichaud, Nathaniel
Yanagiya, Akiko
Tahmasebi, Soroush
Jafarnejad, Seyed Mehdi
Jia, Jian-Jun
Pelin, Adrian
Diallo, Jean-Simon
Le Boeuf, Fabrice
Bell, John Cameron
Mossman, Karen Louise
Graber, Tyson Ernst
Jaramillo, Maritza
Sonenberg, Nahum
Alain, Tommy
Pokaż więcej
Temat :
MESH: Adaptator Proteins, Signal Transducing/genetics
MESH: Adaptator Proteins, Signal Transducing/metabolism
MESH: Mice
MESH: Neoplasms/complications
MESH: Animals
MESH: Neoplasms/genetics
MESH: Neoplasms/pathology
MESH: Neoplasms/virology
MESH: Organisms, Genetically Modified
MESH: Phosphoproteins/genetics
MESH: Phosphoproteins/metabolims
MESH: Protein Kinase Inhibitors/pharmacology
MESH: Herpes Simplex/complications
MESH: Signal Transduction/genetics
MESH: TOR Serine-Threonine Kinases/antagonists & inhibitiors
MESH: TOR Serine-Threonine Kinases/chemistry
MESH: Catalytic Domain/drug effects
MESH: Ubiquitin-Protein Ligases/deficiency
MESH: Ubiquitin-Protein Ligases/genetics
MESH: Vero Cells
MESH: Cells, Cultured
MESH: Cercopithecus aethiops
MESH: Eukaryotic Initiation Factor-4E/genetics
MESH: Herpes Simplex/genetics
MESH: Eukaryotic Initiation Factor-4E/metabolism
MESH: Gene Expression Regulation, Neoplastic/drug effects
MESH: HEK293 Cells
MESH: Herpes Simplex/pathology
MESH: Herpesvirus 1, Human/drug effects
MESH: Herpesvirus 1, Human/genetics
MESH: Humans
MESH: Immediate-Early Proteins/deficiency
MESH: Immediate-Early Proteins/genetics
[SDV.CAN]Life Sciences [q-bio]/Cancer
Źródło :
PLoS Pathogens, Public Library of Science, 2018, 14 (8), pp.e1007264. ⟨10.1371/journal.ppat.1007264⟩
Tytuł :
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis
Autorzy :
Chadi Zakaria
Polen Sean
Huy-Dung Hoang
Louis-Phillipe Leroux
Margaret Watson
Samuel Tekeste Workenhe
Jaclyn Hearnden
Dana Pearl
Vinh Tai Truong
Nathaniel Robichaud
Akiko Yanagiya
Soroush Tahmasebi
Seyed Mehdi Jafarnejad
Jian-Jun Jia
Adrian Pelin
Jean-Simon Diallo
Fabrice Le Boeuf
John Cameron Bell
Karen Louise Mossman
Tyson Ernst Graber
Maritza Jaramillo
Nahum Sonenberg
Tommy Alain
Pokaż więcej
Temat :
MESH: Animals
RC581-607
MESH: Herpes Simplex/pathology
MESH: Catalytic Domain/drug effects
MESH: Adaptator Proteins, Signal Transducing/metabolism
MESH: Herpesvirus 1, Human/genetics
Immunologic diseases. Allergy
MESH: Signal Transduction/genetics
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH: Phosphoproteins/genetics
MESH: Herpesvirus 1, Human/drug effects
MESH: TOR Serine-Threonine Kinases/antagonists & inhibitiors
MESH: Eukaryotic Initiation Factor-4E/metabolism
MESH: Adaptator Proteins, Signal Transducing/genetics
MESH: Cercopithecus aethiops
MESH: Organisms, Genetically Modified
MESH: Neoplasms/pathology
MESH: Ubiquitin-Protein Ligases/deficiency
MESH: HEK293 Cells
MESH: Eukaryotic Initiation Factor-4E/genetics
MESH: Neoplasms/genetics
MESH: Neoplasms/virology
MESH: Cells, Cultured
MESH: Humans
MESH: Immediate-Early Proteins/deficiency
MESH: Neoplasms/complications
QH301-705.5
MESH: Mice
MESH: Protein Kinase Inhibitors/pharmacology
MESH: Gene Expression Regulation, Neoplastic/drug effects
MESH: Immediate-Early Proteins/genetics
MESH: Ubiquitin-Protein Ligases/genetics
MESH: Herpes Simplex/genetics
MESH: TOR Serine-Threonine Kinases/chemistry
Biology (General)
MESH: Phosphoproteins/metabolims
MESH: Herpes Simplex/complications
MESH: Vero Cells
Źródło :
Zakaria, C, Sean, P, Hoang, H-D, Leroux, L-P, Watson, M, Workenhe, S T, Hearnden, J, Pearl, D, Truong, V T, Robichaud, N, Yanagiya, A, Tahmasebi, S, Jafarnejad, S M, Jia, J-J, Pelin, A, Diallo, J-S, Le Boeuf, F, Bell, J C, Mossman, K L, Graber, T E, Jaramillo, M, Sonenberg, N & Alain, T 2018, ' Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis ', PLoS Pathogens, vol. 14, no. 8, e1007264 . https://doi.org/10.1371/journal.ppat.1007264
PLoS Pathogens, Public Library of Science, 2018, 14 (8), pp.e1007264. ⟨10.1371/journal.ppat.1007264⟩
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)
Opis pliku :
application/pdf
Tytuł :
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Autorzy :
Sanchez-Vega, F.
Mina, M.
Armenia, J.
Chatila, W. K.
Luna, A.
La, K. C.
Dimitriadoy, S.
Liu, D. L.
Kantheti, H. S.
Saghafinia, S.
Chakravarty, D.
Daian, F.
Gao, Q.
Bailey, M. H.
Liang, W. -W.
Foltz, S. M.
Shmulevich, I.
Ding, L.
Heins, Z.
Ochoa, A.
Gross, B.
Gao, J.
Zhang, H.
Kundra, R.
Kandoth, C.
Bahcecİ, I
Dervishi, L.
Dogrusoz, U.
Zhou, W.
Shen, H.
Laird, P. W.
Way, G. P.
Greene, C. S.
Liang, H.
Xiao, Y.
Wang, C.
Iavarone, A.
Berger, A. H.
Bivona, T. G.
Lazar, A. J.
Hammer, G. D.
Giordano, T.
Kwong, L. N.
McArthur, G.
Huang, C.
Tward, A. T.
Frederick, M. J.
McCormick, F.
Meyerson, M.
The Cancer Genome Atlas Research Network
van Allen, E. M.
Cherniack, A. D.
Ciriello, G.
Sander, C.
Schultz, N.
Pokaż więcej
Temat :
precision oncology
COMPREHENSIVE MOLECULAR CHARACTERIZATION
therapeutics
PanCanAtlas
Databases, Genetic
Transforming Growth Factor beta
610 Medicine & health
Biochemistry & Molecular Biology
06 Biological Sciences
Cancer Genome Atlas Research Network
SIGNATURES
cancer genome atlas
MUTATIONS
combination therapy
cancer genomics
Genes, Neoplasm
Humans
Neoplasms/genetics
Neoplasms/pathology
Phosphatidylinositol 3-Kinases/genetics
Phosphatidylinositol 3-Kinases/metabolism
Signal Transduction/genetics
Transforming Growth Factor beta/genetics
Transforming Growth Factor beta/metabolism
Tumor Suppressor Protein p53/genetics
Tumor Suppressor Protein p53/metabolism
Wnt Proteins/genetics
Wnt Proteins/metabolism
TCGA
pan-cancer
signaling pathways
whole exome sequencing
Wnt Proteins
Tumor Suppressor Protein p53
EXPRESSION
Life Sciences & Biomedicine
GENES
Signal Transduction
Developmental Biology
Article
Phosphatidylinositol 3-Kinases
Cell Biology
Science & Technology
11 Medical and Health Sciences
Neoplasms
LANDSCAPE
Źródło :
Sanchez-Vega, Francisco; Mina, Marco; Armenia, Joshua; Chatila, Walid K; Luna, Augustin; La, Konnor C; Dimitriadoy, Sofia; Liu, David L; Kantheti, Havish S; Saghafinia, Sadegh; Chakravarty, Debyani; Daian, Foysal; Gao, Qingsong; Bailey, Matthew H; Liang, Wen-Wei; Foltz, Steven M; Shmulevich, Ilya; Ding, Li; Heins, Zachary; Ochoa, Angelica; ... (2018). Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell, 173(2), 321-337.e10. Cell Press 10.1016/j.cell.2018.03.035
Cell, vol. 173, no. 2, pp. 321-337.e10
Opis pliku :
application/pdf
Tytuł :
Human cytomegalovirus tegument protein pp65 (pUL83) dampens type I interferon production by inactivating the DNA sensor cGAS without affecting STING
Autorzy :
Biolatti, Matteo
Dell'Oste, Valentina
Pautasso, Sara
Gugliesi, Francesca
von Einem, Jens
Krapp, Christian
Jakobsen, Martin Roelsgaard
Borgogna, Cinzia
Gariglio, Marisa
De Andrea, Marco
Landolfo, Santo
Pokaż więcej
Temat :
Immune Evasion/genetics
Immunity, Innate/genetics
viruses
surgical procedures, operative
Signal Transduction/genetics
Virus-Cell Interactions
Nucleotidyltransferases/genetics
Interferon Type I/genetics
Viral Matrix Proteins/genetics
Protein Binding
biochemical phenomena, metabolism, and nutrition
Cytomegalovirus/genetics
Cytomegalovirus Infections/genetics
virus diseases
HEK293 Cells
Humans
Membrane Proteins/genetics
Phosphoproteins/genetics
Źródło :
Biolatti, M, Dell'Oste, V, Pautasso, S, Gugliesi, F, von Einem, J, Krapp, C, Jakobsen, M R, Borgogna, C, Gariglio, M, De Andrea, M & Landolfo, S 2018, ' Human cytomegalovirus tegument protein pp65 (pUL83) dampens type I interferon production by inactivating the DNA sensor cGAS without affecting STING ', Journal of Virology, vol. 92, no. 6, e01774-17 . https://doi.org/10.1128/JVI.01774-17
Tytuł :
MicroRNA-375 regulates proliferation and apoptosis of glioma cancer cells by inhibiting CTGF-EGFR signaling pathway
Autorzy :
Zhang, L X
Jin, W
Zheng, J
Dai, Y X
Song, Y
Ni, H B
Jiang, J
Liang, W B
Pokaż więcej
Temat :
Apoptosis/genetics
Cell Cycle
Cell Movement/genetics
Cell Proliferation/genetics
Connective Tissue Growth Factor/genetics
ErbB Receptors/genetics
Female
Glioma/genetics
Humans
MicroRNAs/genetics
Signal Transduction/genetics
Źródło :
Bratislava Medical Journal, 119(1), 17
Opis pliku :
text/plain
Tytuł :
Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI
Autorzy :
Zhang, Dongfeng
Wang, Weijing
Jiang, Wenjie
Hou, Lin
Duan, Haiping
Wu, Yili
Xu, Chunsheng
Tan, Qihua
Li, Shuxia
Pokaż więcej
Temat :
Hub gene
Biotechnology
Research Article
Body Mass Index
Signal Transduction/genetics
Differentially expressed genes
Monozygotic twins
Middle Aged
Twins, Monozygotic/genetics
BMI
Gene module
Obesity
WGCNA
QH426-470
Gene Regulatory Networks
Genetics
Obesity/genetics
Adult
Female
Humans
Male
TP248.13-248.65
Źródło :
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
Wang, W, Jiang, W, Hou, L, Duan, H, Wu, Y, Xu, C, Tan, Q, Li, S & Zhang, D 2017, ' Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI. ', BMC Genomics, vol. 18, 872 . https://doi.org/10.1186/s12864-017-4257-6
Opis pliku :
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Tytuł :
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness
Autorzy :
Rueedi, Rico
Deloukas, Panos
Heilmann-Heimbach, Stefanie
Herold, Christine
Hochfeld, Lara M.
Hillmer, Axel M.
Nyholt, Dale R.
Hecker, Julian
Javed, Asif
Chew, Elaine G. Y.
Pechlivanis, Sonali
Drichel, Dmitriy
Heng, Xiu Ting
del Rosario, Ricardo C. -H.
Fier, Heide L.
Paus, Ralf
Galesloot, Tessel E.
Moebus, Susanne
Anhalt, Thomas
Prabhakar, Shyam
Li, Rui
Kanoni, Stavroula
Papanikolaou, George
Kutalik, Zoltán
Philpott, Michael P.
Waeber, Gérard
Spector, Tim D.
Vollenweider, Peter
Kiemeney, Lambertus A. L. M.
Dedoussis, George
Richards, J. Brent
Nothnagel, Michael
Martin, Nicholas G.
Becker, Tim
Hinds, David A.
Nöthen, Markus M.
Pokaż więcej
Temat :
Chemistry(all)
Biochemistry, Genetics and Molecular Biology(all)
Physics and Astronomy(all)
3-Oxo-5-alpha-Steroid 4-Dehydrogenase/genetics
Adipogenesis/genetics
Alopecia/genetics
Case-Control Studies
Fibroblast Growth Factor 5/genetics
Genetic Association Studies
Genome-Wide Association Study
Genotype
Humans
Intercellular Signaling Peptides and Proteins/genetics
Interferon Regulatory Factors/genetics
Male
Melatonin
Membrane Proteins/genetics
Phenotype
Signal Transduction/genetics
Trans-Activators/genetics
Article
Źródło :
Nature communications, vol. 8, pp. 14694
Nature Communications, 8, 14694
Heilmann-Heimbach, S, Herold, C, Hochfeld, L M, Hillmer, A M, Nyholt, D R, Hecker, J, Javed, A, Chew, E G Y, Pechlivanis, S, Drichel, D, Heng, X T, Del Rosario, R C H, Fier, H L, Paus, R, Rueedi, R, Galesloot, T E, Moebus, S, Anhalt, T, Prabhakar, S, Li, R, Kanoni, S, Papanikolaou, G, Kutalik, Z, Deloukas, P, Philpott, M P, Waeber, G, Spector, T D, Vollenweider, P, Kiemeney, L A L M, Dedoussis, G, Richards, J B, Nothnagel, M, Martin, N G, Becker, T, Hinds, D A & Nöthen, M M 2017, ' Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness ', Nature Communications, vol. 8, 14694 . https://doi.org/10.1038/ncomms14694
Opis pliku :
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