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Tytuł :
Suppression of ovarian cancer by low-intensity ultrasound through depletion of IL-6/STAT3 inflammatory pathway-maintained cancer stemness.
Autorzy :
Gong T; Medical Ultrasound Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, 710061, China.
Zhang P; Medical Ultrasound Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, 710061, China.
Jia L; First Department of Gynecology, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, 710061, China.
Pan Y; Medical Ultrasound Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, 710061, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 04; Vol. 526 (3), pp. 820-826. Date of Electronic Publication: 2020 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Ultrasonic Waves*
Interleukin-6/*antagonists & inhibitors
Ovarian Neoplasms/*metabolism
STAT3 Transcription Factor/*metabolism
Ultrasonic Therapy/*methods
Cell Line, Tumor ; Cell Proliferation/radiation effects ; DNA/metabolism ; Female ; Humans ; Inflammation/metabolism ; Neoplasms, Experimental ; Neoplastic Stem Cells/metabolism ; Oncogenes ; Phosphorylation/radiation effects ; Protein Binding/radiation effects ; Signal Transduction
Czasopismo naukowe
Tytuł :
Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression.
Autorzy :
Masjedi A; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmadi A; Department of Chemical and Materials Engineering, The University of Alabama in Huntsville, AL 35899, USA.
Atyabi F; Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Farhadi S; Student Research Committee, Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Irandoust M; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khazaei-Poul Y; Student Research Committee, Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ghasemi Chaleshtari M; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Edalati Fathabad M; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Baghaei M; Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Haghnavaz N; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hojjat-Farsangi M; Bioclinicum, Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden; The Persian Gulf Marine Biotechnology Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran.
Ghalamfarsa G; Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Sabz G; Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Hasanzadeh S; Department of Internal Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.
Jadidi-Niaragh F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Apr 15; Vol. 149, pp. 487-500. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*therapy
Chitosan/*chemistry
Interleukin-6/*genetics
Neovascularization, Pathologic/*therapy
STAT3 Transcription Factor/*genetics
Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Chitosan/pharmacology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Hyaluronan Receptors/genetics ; Hyaluronic Acid/chemistry ; Interleukin-6/antagonists & inhibitors ; Nanoparticles/chemistry ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; RNA, Small Interfering/chemistry ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology ; STAT3 Transcription Factor/antagonists & inhibitors ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
IL-6 trans- signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
Autorzy :
Yang X; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Yan H; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Jiang N; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Yu Z; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Yuan J; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Ni Z; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
Fang W; Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Center for Peritoneal Dialysis Research, Shanghai, China.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Feb 01; Vol. 318 (2), pp. F338-F353. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Communication*
Human Umbilical Vein Endothelial Cells/*metabolism
Interleukin-6/*metabolism
Peritoneal Fibrosis/*metabolism
Peritoneum/*metabolism
STAT3 Transcription Factor/*metabolism
Angiogenic Proteins/metabolism ; Animals ; Capillary Permeability ; Cells, Cultured ; Cytokine Receptor gp130/metabolism ; Disease Models, Animal ; Epithelial-Mesenchymal Transition ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Male ; Mice, Inbred C57BL ; Neovascularization, Physiologic ; Peritoneal Dialysis ; Peritoneal Fibrosis/etiology ; Peritoneal Fibrosis/pathology ; Peritoneum/pathology ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Kang-ai Injection (康艾注射液) Inhibits Gastric Cancer Cells Proliferation through IL-6/STAT3 Pathway
Autorzy :
Zheng, Chun-leiAff1, Aff2, Aff3
Hou, Ke-zuoAff1, Aff2, Aff3
Wang, An-qiAff1, Aff2, Aff3
Fang, Wan-xiaAff1, Aff2, Aff3
Yu, Shi-tongAff1, Aff2, Aff3
Liang, Jin-eAff1, Aff2, Aff3
Qi, Hai-yanAff1, Aff2, Aff3
Qu, Xiu-juanAff1, Aff2, Aff3
Liu, Yun-pengAff1, Aff2, Aff3
Che, Xiao-fangAff1, Aff2, Aff3
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Źródło :
Chinese Journal of Integrative Medicine. :1-7
Czasopismo naukowe
Tytuł :
STAT3 polymorphisms and IL-6 polymorphism are associated with the risk of basal cell carcinoma in patients from northern Poland.
Autorzy :
Sławińska M; Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland. .
Zabłotna M; Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland.
Gleń J; Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland.
Lakomy J; Department of Patomorphology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland.
Nowicki RJ; Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland.
Sobjanek M; Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214, Gdańsk, Poland.
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Źródło :
Archives of dermatological research [Arch Dermatol Res] 2019 Nov; Vol. 311 (9), pp. 697-704. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Predisposition to Disease*
Carcinoma, Basal Cell/*genetics
Interleukin-6/*genetics
STAT3 Transcription Factor/*genetics
Skin Neoplasms/*genetics
Aged ; Aged, 80 and over ; Alleles ; Carcinoma, Basal Cell/blood ; Carcinoma, Basal Cell/pathology ; Case-Control Studies ; Female ; Healthy Volunteers ; Humans ; Interleukin-6/blood ; Male ; Middle Aged ; Poland ; Polymorphism, Single Nucleotide ; Skin/pathology ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation
Autorzy :
Hongda Ding
Xixia Zhang
Yang Su
Changjun Jia
Chaoliu Dai
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Temat :
Hepatocellular carcinoma
Lipopolysaccharides
G-protein alpha-subunit
Signal transducer and activator of transcription 3
Interleukin-6
Cytology
QH573-671
Źródło :
Cellular & Molecular Biology Letters , Vol 25, Iss 1, Pp 1-17 (2020)
Opis pliku :
electronic resource
Relacje :
http://link.springer.com/article/10.1186/s11658-020-00204-1; https://doaj.org/toc/1425-8153; https://doaj.org/toc/1689-1392
Dostęp URL :
https://doaj.org/article/43a26bc0f42f4f3abd6e88109563fc70
Czasopismo naukowe
Tytuł :
The correlation between low vitamin D status and renal interleukin-6/STAT3 hyper-activation in patients with clear cell renal cell carcinoma.
Autorzy :
Song J; Department of Urology, Second Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Xu S; Department of Oncology, First Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Zhang ZH; Department of Urology, Second Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Chen YH; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China.
Gao L; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China.
Xie DD; Department of Urology, Second Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Sun GP; Department of Oncology, First Affiliated Hospital, Anhui Medical University, Hefei 230022, China.
Yu DX; Department of Urology, Second Affiliated Hospital, Anhui Medical University, Hefei 230022, China. Electronic address: .
Xu DX; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China. Electronic address: .
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Źródło :
Steroids [Steroids] 2019 Oct; Vol. 150, pp. 108445. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Renal Cell/*blood
Carcinoma, Renal Cell/*metabolism
Interleukin-6/*blood
Kidney Neoplasms/*blood
Kidney Neoplasms/*metabolism
STAT3 Transcription Factor/*metabolism
Vitamin D/*blood
Carcinoma, Renal Cell/diagnosis ; Case-Control Studies ; Female ; Humans ; Kidney Neoplasms/diagnosis ; Male ; Middle Aged ; Vitamin D Deficiency/blood
Czasopismo naukowe
Tytuł :
Long noncoding RNA DANCR promotes nasopharyngeal carcinoma progression by interacting with STAT3, enhancing IL-6/JAK1/STAT3 signaling.
Autorzy :
Zhang X; Department of Otorhinolaryngology, China Medical University Affiliated ShengJing Hospital, Shenyang City, Liaoning Province, China.
Yang J; Department of Otorhinolaryngology, China Medical University Affiliated ShengJing Hospital, Shenyang City, Liaoning Province, China.
Bian Z; Department of Otorhinolaryngology, China Medical University Affiliated ShengJing Hospital, Shenyang City, Liaoning Province, China.
Shi D; Department of Otorhinolaryngology, China Medical University Affiliated ShengJing Hospital, Shenyang City, Liaoning Province, China.
Cao Z; Department of Otorhinolaryngology, China Medical University Affiliated ShengJing Hospital, Shenyang City, Liaoning Province, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2019 May; Vol. 113, pp. 108713. Date of Electronic Publication: 2019 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6/*metabolism
Janus Kinase 1/*metabolism
Nasopharyngeal Carcinoma/*pathology
Nasopharyngeal Neoplasms/*pathology
RNA, Long Noncoding/*genetics
STAT3 Transcription Factor/*metabolism
Cell Line, Tumor ; Cell Proliferation/genetics ; Humans ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Carcinoma/metabolism ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/metabolism ; Neoplasm Invasiveness ; Signal Transduction
Czasopismo naukowe
Tytuł :
Bazedoxifene exhibits growth suppressive activity by targeting interleukin-6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma.
Autorzy :
Ma H; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Division of Cardiology, Departments of Internal Medicine, First People's Hospital of ShangQiu, Shangqiu, China.
Yan D; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang Y; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shi W; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu T; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhao C; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Division of Cardiology, Tianjin First Center Hospital, Tianjin, China.
Huo S; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Duan J; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tao J; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhai M; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Luo P; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Guo J; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tian L; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mageta L; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jou D; Center for Childhood Cancer, Department of Pediatrics, The Research Institute at Nationwide Children's Hospital, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
Zhang C; Departments of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li C; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Lin J; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Lv J; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li S; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lin L; Division of Cardiology, Departments of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Cancer science [Cancer Sci] 2019 Mar; Vol. 110 (3), pp. 950-961. Date of Electronic Publication: 2019 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*drug therapy
Cell Proliferation/*drug effects
Glycoproteins/*metabolism
Indoles/*pharmacology
Interleukin-6/*metabolism
Liver Neoplasms/*drug therapy
STAT3 Transcription Factor/*metabolism
Animals ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Hep G2 Cells ; Humans ; Interleukin-4/metabolism ; Leukemia Inhibitory Factor/metabolism ; Liver Neoplasms/metabolism ; Mice ; Mice, Nude ; Phosphorylation/drug effects ; Receptors, Interleukin-6/metabolism ; Signal Transduction/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Neuropilin-1 (NRP-1) upregulated by IL-6/STAT3 signaling contributes to invasion in pancreatic neuroendocrine neoplasms.
Autorzy :
Yang Y; Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Yang L; Center for Medical Experiments, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Li Y; Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address: .
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Źródło :
Human pathology [Hum Pathol] 2018 Nov; Vol. 81, pp. 192-200. Date of Electronic Publication: 2018 Jul 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement/*drug effects
Interleukin-6/*pharmacology
Neuroendocrine Tumors/*metabolism
Neuropilin-1/*metabolism
Pancreatic Neoplasms/*metabolism
STAT3 Transcription Factor/*metabolism
Signal Transduction/*drug effects
Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness ; Neoplasm Staging ; Neuroendocrine Tumors/genetics ; Neuroendocrine Tumors/secondary ; Neuropilin-1/genetics ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/pathology ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; STAT3 Transcription Factor/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
IL-6/STAT3 pathway intermediates M1/M2 macrophage polarization during the development of hepatocellular carcinoma.
Autorzy :
Yin Z; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Ma T; Gynaecology and Obstetrics Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Lin Y; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Lu X; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Zhang C; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Chen S; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Jian Z; General Surgery Department, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
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Źródło :
Journal of cellular biochemistry [J Cell Biochem] 2018 Nov; Vol. 119 (11), pp. 9419-9432. Date of Electronic Publication: 2018 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Hepatocellular/*metabolism
Interleukin-6/*metabolism
Liver Neoplasms/*metabolism
Macrophages/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Blotting, Western ; Carcinoma, Hepatocellular/genetics ; Cell Line ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Interleukin-6/genetics ; Liver Neoplasms/genetics ; Mice ; Mice, Nude ; RAW 264.7 Cells ; Reverse Transcriptase Polymerase Chain Reaction ; STAT3 Transcription Factor/genetics ; Signal Transduction/genetics ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Interleukin-6 signalling mediates Galectin-8 co-stimulatory activity of antigen-specific CD4 T-cell response.
Autorzy :
Carabelli J; Laboratorio de Inmunología Molecular, Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
Prato CA; Laboratorio de Inmunología Molecular, Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
Sanmarco LM; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Córdoba, Argentina.
Aoki MP; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Córdoba, Argentina.
Campetella O; Laboratorio de Inmunología Molecular, Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
Tribulatti MV; Laboratorio de Inmunología Molecular, Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
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Źródło :
Immunology [Immunology] 2018 Nov; Vol. 155 (3), pp. 379-386. Date of Electronic Publication: 2018 Jul 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen Presentation*
Lymphocyte Activation*
CD4-Positive T-Lymphocytes/*immunology
Galectins/*immunology
Interleukin-6/*immunology
Animals ; Immunization ; Mice ; Mice, Knockout ; Peptides/immunology ; STAT3 Transcription Factor/immunology
Czasopismo naukowe
Tytuł :
The IL-6/STAT3 pathway regulates adhesion molecules and cytoskeleton of endothelial cells in thromboangiitis obliterans.
Autorzy :
Wei Z; Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: .
Jiang W; Key Laboratory of Hepatosplenic Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Wang H; Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li H; Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Tang B; Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Liu B; Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Jiang H; Key Laboratory of Hepatosplenic Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Sun X; Key Laboratory of Hepatosplenic Surgery, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: .
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Źródło :
Cellular signalling [Cell Signal] 2018 Apr; Vol. 44, pp. 118-126. Date of Electronic Publication: 2018 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelial Cells/*cytology
Intercellular Adhesion Molecule-1/*metabolism
Interleukin-6/*metabolism
STAT3 Transcription Factor/*metabolism
Thromboangiitis Obliterans/*metabolism
Vascular Cell Adhesion Molecule-1/*metabolism
Acetylation ; Adult ; Arteries/physiopathology ; Focal Adhesion Kinase 1/metabolism ; Humans ; Leg/blood supply ; Male ; Matrix Metalloproteinase 9/metabolism ; Middle Aged ; Nitric Oxide Synthase Type III/metabolism ; Phosphorylation ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Tytuł :
Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy.
Autorzy :
Chen F; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Chen D; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Zhang Y; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Jin L; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Zhang H; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Wan M; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Pan T; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Wang X; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Su Y; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China.
Xu Y; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China; Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Ye J; State Key Laboratory of Natural Medicines, Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210006, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2017 Dec 16; Vol. 494 (3-4), pp. 534-541. Date of Electronic Publication: 2017 Oct 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*administration & dosage
Cardiomyopathies/*immunology
Cardiomyopathies/*pathology
Interleukin-6/*immunology
Myocytes, Cardiac/*immunology
Myocytes, Cardiac/*pathology
STAT3 Transcription Factor/*immunology
Animals ; Cardiomyopathies/chemically induced ; Cells, Cultured ; Hypertrophy/immunology ; Hypertrophy/pathology ; Interleukin-6/genetics ; Male ; Mice ; Mice, Knockout ; Myocytes, Cardiac/drug effects
Czasopismo naukowe
Tytuł :
The ROS-mediated activation of IL-6/STAT3 signaling pathway is involved in the 27-hydroxycholesterol-induced cellular senescence in nerve cells.
Autorzy :
Liu J; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Liu Y; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Chen J; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Hu C; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Teng M; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Jiao K; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Shen Z; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Zhu D; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Yue J; Department of Nutrition and Food Hygiene, School of Public Health, Gansu University of Chinese Medical, Lanzhou 730000, China.
Li Z; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China. Electronic address: .
Li Y; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing 211166, China. Electronic address: .
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2017 Dec; Vol. 45 (Pt 1), pp. 10-18. Date of Electronic Publication: 2017 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Microglia*
Cell Survival/*drug effects
Hydroxycholesterols/*toxicity
Interleukin-6/*metabolism
Reactive Oxygen Species/*metabolism
STAT3 Transcription Factor/*metabolism
Animals ; Cell Line ; Cell Survival/physiology ; Enzyme-Linked Immunosorbent Assay ; Gene Expression Regulation/drug effects ; Humans ; Hydroxycholesterols/administration & dosage ; Mice ; Pheochromocytoma ; Rats
Czasopismo naukowe
Tytuł :
Activation of the B-cell receptor successively activates NF-κB and STAT3 in chronic lymphocytic leukemia cells.
Autorzy :
Rozovski U; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.; Division of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Harris DM; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Li P; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Liu Z; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Jain P; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Veletic I; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Ferrajoli A; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Burger J; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Thompson P; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Jain N; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Wierda W; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Keating MJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
Estrov Z; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
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Źródło :
International journal of cancer [Int J Cancer] 2017 Nov 15; Vol. 141 (10), pp. 2076-2081. Date of Electronic Publication: 2017 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Interleukin-6/*metabolism
Leukemia, Lymphocytic, Chronic, B-Cell/*pathology
NF-kappa B/*metabolism
Receptors, Antigen, B-Cell/*metabolism
STAT3 Transcription Factor/*metabolism
Humans ; Interleukin-6/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism ; NF-kappa B/genetics ; Phosphorylation ; Receptors, Antigen, B-Cell/genetics ; STAT3 Transcription Factor/genetics ; Signal Transduction ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Cypermethrin inhibits interleukin-6-induced androgen receptor transactivation through signal transducer and activator of transcription 3.
Autorzy :
Zhou JL; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Ding Z; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Ge X; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Shi QM; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Wang HX; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Chen G; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Li MX; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Wang H; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Ju Q; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Wang Q; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Zhang JP; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Zhang MR; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
Xu LC; a School of Public Health , Xuzhou Medical University, Xuzhou , PR China.
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Źródło :
Toxicology mechanisms and methods [Toxicol Mech Methods] 2017 Nov; Vol. 27 (9), pp. 717-722. Date of Electronic Publication: 2017 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
Insecticides/*pharmacology
Interleukin-6/*physiology
Pyrethrins/*pharmacology
Receptors, Androgen/*genetics
STAT3 Transcription Factor/*metabolism
Transcriptional Activation/*physiology
Animals ; Cell Line ; Humans ; Phosphorylation ; Receptors, Androgen/metabolism
Czasopismo naukowe

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