- Tytuł:
- A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2021 Jun 02; Vol. 16 (6), pp. e0252233. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Drug Synergism*
Angiogenesis Inhibitors/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Chorioallantoic Membrane/*drug effects
Drug Screening Assays, Antitumor/*methods
Glioblastoma/*drug therapy
Neovascularization, Pathologic/*drug therapy
Animals ; Bevacizumab/administration & dosage ; Chickens ; Chorioallantoic Membrane/pathology ; Glioblastoma/blood supply ; Glioblastoma/pathology ; Humans ; Neovascularization, Pathologic/pathology ; Rats ; Sirolimus/administration & dosage ; Sirolimus/analogs & derivatives ; Tumor Cells, Cultured
Czasopismo naukowe