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Tytuł:
Nicotinic Acetylcholine Receptors in Glial Cells as Molecular Target for Parkinson's Disease.
Autorzy:
Soares ÉN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.
Costa ACDS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.
Ferrolho GJ; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.; Laboratory of Neurosciences, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.
Ureshino RP; Department of Biological Sciences, Universidade Federal de São Paulo, Diadema 09961-400, SP, Brazil.; Laboratory of Molecular and Translational Endocrinology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04039-032, SP, Brazil.
Getachew B; Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.; Laboratory of Neurosciences, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, BA, Brazil.
Tizabi Y; Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA.
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Źródło:
Cells [Cells] 2024 Mar 07; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*/metabolism
Receptors, Nicotinic*/metabolism
Neurodegenerative Diseases*/metabolism
Humans ; Nicotine/metabolism ; Dopamine/metabolism ; Astrocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling.
Autorzy:
Dos Santos BL; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.; College of Nursing, Federal University of Vale do São Francisco, Av. José de Sá Maniçoba, S/N, Petrolina 56304-917, PE, Brazil.
Dos Santos CC; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.
da Silva KC; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.
Nonaka CKV; Center of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Teaching (IDOR), Salvador 41253-190, BA, Brazil.
Souza BSF; Center of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Teaching (IDOR), Salvador 41253-190, BA, Brazil.; Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador 40296-710, BA, Brazil.
David JM; Department of General and Inorganic Chemistry, Institute of Chemistry, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
de Oliveira JVR; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.
Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.; National Institute of Translational Neuroscience (INNT), Rio de Janeiro 21941-971, RJ, Brazil.
Butt AM; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK.
da Silva VDA; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.
Costa SL; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.; National Institute of Translational Neuroscience (INNT), Rio de Janeiro 21941-971, RJ, Brazil.; Instituto de Ciências da Saúde, Av. Reitor Miguel Calmon S/N Vale do Canela, Salvador 40110-902, BA, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Biflavonoids*/pharmacology
Alzheimer Disease*/metabolism
MicroRNAs*/genetics
Humans ; Microglia/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Amyloid beta-Peptides/metabolism ; Cytokines/metabolism ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of the Flavonoid Rutin on the Modulation of the Myenteric Plexuses in an Experimental Model of Parkinson's Disease.
Autorzy:
de Jesus LB; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
Frota AF; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
de Araújo FM; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
Jesus RLC; Cardiovascular Physiology and Pharmacology Laboratory, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.; National Institute for Translational Neurosciences (INCT/CNPq INNT), Rio de Janeiro 21941-902, RJ, Brazil.
de Vasconcelos DFSA; Cardiovascular Physiology and Pharmacology Laboratory, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
Gois MB; Faculty of Health Sciences, Federal University of Rondonópolis, Rondonópolis 78736-900, MT, Brazil.
Baccan GC; Laboratory of Neuroendocrine-Immunology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.
Costa SL; Laboratory of Neurochemistry and Cellular Biology, Federal University of Bahia, Salvador 40170-110, BA, Brazil.; National Institute for Translational Neurosciences (INCT/CNPq INNT), Rio de Janeiro 21941-902, RJ, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 15; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Myenteric Plexus*
Parkinson Disease*/drug therapy
Male ; Rats ; Animals ; Rats, Wistar ; Flavonoids/pharmacology ; Flavonoids/therapeutic use ; Rutin/pharmacology ; Rutin/therapeutic use ; Disease Models, Animal ; Dopaminergic Neurons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of Plant-Derived Compounds on Amyotrophic Lateral Sclerosis.
Autorzy:
de Oliveira LMG; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
Carreira RB; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
de Oliveira JVR; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
do Nascimento RP; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
Dos Santos Souza C; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.
Trias E; Institut Pasteur de Montevideo, Montevideo, Uruguay.
da Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil. .
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2023 Jun; Vol. 41 (3), pp. 288-309. Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/drug therapy
Amyotrophic Lateral Sclerosis*/complications
Humans ; Riluzole ; Edaravone/therapeutic use ; Glutamic Acid ; Phytochemicals/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protective Effects of Flavonoid Rutin Against Aminochrome Neurotoxicity.
Autorzy:
De Araújo FM; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.; Clinical & Experimental Neuroscience (NiCE). Institute for Bio-Health Research of Murcia (IMIB), Institute for Aging Research (IUIE), School of Medicine, Campus Mare Nostrum, University of Murcia, Murcia, Spain.
Frota AF; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
de Jesus LB; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Cuenca-Bermejo L; Clinical & Experimental Neuroscience (NiCE). Institute for Bio-Health Research of Murcia (IMIB), Institute for Aging Research (IUIE), School of Medicine, Campus Mare Nostrum, University of Murcia, Murcia, Spain.
Ferreira KMS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Santos CC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Soares EN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Souza JT; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Sanches FS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Costa ACS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Farias AA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
de Fatima Dias Costa M; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Munoz P; Instituto de Ciencias Biomedicas, Faculdad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.; Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Independencia, 1027, Santiago, Chile.
Menezes-Filho JA; Graduate Program in Pharmacy, College of Pharmacy, Federal University of Bahia, Salvador, Brazil.
Segura-Aguilar J; Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Independencia, 1027, Santiago, Chile.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
Herrero MT; Clinical & Experimental Neuroscience (NiCE). Institute for Bio-Health Research of Murcia (IMIB), Institute for Aging Research (IUIE), School of Medicine, Campus Mare Nostrum, University of Murcia, Murcia, Spain. .
Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2023 Jun; Vol. 41 (3), pp. 224-241. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Neurotoxicity Syndromes*/drug therapy
Neurotoxicity Syndromes*/prevention & control
Neurotoxicity Syndromes*/metabolism
Parkinson Disease*/metabolism
Neuroprotective Agents*/therapeutic use
Animals ; Mice ; Glial Cell Line-Derived Neurotrophic Factor/metabolism ; Flavonoids/pharmacology ; Rutin/pharmacology ; Dopamine/metabolism ; Dopaminergic Neurons ; Anti-Inflammatory Agents/pharmacology ; Disease Models, Animal ; Mice, Inbred C57BL ; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome.
Autorzy:
Dos Santos BL; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.; College of Nursing, Federal University of Vale do São Francisco, Petrolina 56304-917, Pernambuco, Brazil.
Dos Santos CC; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
Soares JRP; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
da Silva KC; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
de Oliveira JVR; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
Pereira GS; Group of Studies and Research for Health Development, University Salvador, Salvador 40140-110, Bahia, Brazil.
de Araújo FM; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.; Group of Studies and Research for Health Development, University Salvador, Salvador 40140-110, Bahia, Brazil.
Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
David JM; Department of General and Inorganic Chemistry, Institute of Chemistry, University Federal da Bahia, Salvador 40170-110, Bahia, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
Butt AM; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.
Costa SL; Laboratory of Neurochemistry and Cellular Biology, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, Bahia, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2023 May 05; Vol. 15 (5). Date of Electronic Publication: 2023 May 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species.
Autorzy:
Santos CC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Cardim-Pires TR; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Shvachiy L; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Gottingen, Göttingen, Germany.; Faculdade de Medicina, Centro Cardiovascular da Universidade de Lisboa, Universidade de Lisboa, Av Prof Egas Moniz, 1649-028, Lisbon, Portugal.
Fonseca-Fonseca LA; Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba.
Muñoz P; Instituto de Ciencias Biomedicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.
Almeida ÁMAN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Costa ACS; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Teles-Souza J; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Ochoa-Rodríguez E; Organic Synthesis Laboratory of the Faculty of Chemistry of the University of Havana, Havana, Cuba.
de Fátima Dias Costa M; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Palhano FL; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Segura-Aguilar J; Molecular & Clinical Pharmacology, Faculty of Medicine, ICBM, University of Chile, Santiago, Chile.
Barbosa DB; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
do Bomfim MR; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
Dos Santos Junior MC; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
Leite FHA; Laboratory of Molecular Modeling, Department of Health, State University of Feira de Santana, Feira de Santana, Brazil.
da Rocha Pita SS; Bioinformatics and Molecular Modeling Laboratory (LaBiMM), Federal University of Bahia - College of Pharmacy, Salvador, Brazil.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil.
Núñez-Figueredo Y; Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba.
Outeiro TF; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Gottingen, Göttingen, Germany.; Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.; Scientific Employee With an Honorary Contract at German Center for Neurodegenerative Diseases (DZNE), 37075, Göttingen, Germany.
Foguel D; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia - Institute of Health Sciences, Salvador, 40110-100, Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2022 Dec; Vol. 40 (6), pp. 2135-2147. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroblastoma*
Parkinson Disease*/drug therapy
Dihydropyridines*
Humans ; alpha-Synuclein ; Benzodiazepines ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Astrocyte Reaction to Catechol-Induced Cytotoxicity Relies on the Contact with Microglia Before Isolation.
Autorzy:
Borges JMP; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil. .; Department of Science and Technology, Southwest Bahia State University (UESB), 45.208-409, Jequie, BA, Brazil. .
de Jesus LB; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil.
Dos Santos Souza C; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil.
da Silva VDA; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil.
Costa SL; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil.
de Fátima Dias Costa M; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil.
El-Bachá RS; Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA), 40.110-902, Salvador, Bahia (BA), Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2022 Aug; Vol. 40 (4), pp. 973-994. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Microglia*/metabolism
Animals ; Catechols/toxicity ; Cells, Cultured ; Interleukin-10/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With Neospora caninum .
Autorzy:
Argolo DS; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Borges JMP; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.; Department of Science and Technologies University of Southwest of Bahia, Brazil.
Freitas LDS; Laboratory of Biochemistry and Veterinary Immunology Federal University of Recôncavo of Bahia, Brazil.
Pina GA; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Grangeiro MS; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Pinheiro AM; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.; Laboratory of Biochemistry and Veterinary Immunology Federal University of Recôncavo of Bahia, Brazil.
Souza Conceição R; Laboratory of Phytochemistry, Department of Health, State University of Feira de Santana (UEFS), Brazil.
Branco A; Laboratory of Phytochemistry, Department of Health, State University of Feira de Santana (UEFS), Brazil.
Guillemin G; Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Costa SL; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
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Źródło:
International journal of tryptophan research : IJTR [Int J Tryptophan Res] 2022 Jan 30; Vol. 15, pp. 11786469211069946. Date of Electronic Publication: 2022 Jan 30 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma.
Autorzy:
do Nascimento RP; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
Dos Santos BL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.; Academic College of Nurse, Department of Health, Federal University of Vale do São Francisco, Petrolina 56304-205, Pernambuco, Brazil.
Amparo JAO; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
Soares JRP; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
da Silva KC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
Santana MR; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
Almeida ÁMAN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.
Costa MFD; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.; National Institute for Translational Neurosciences (INCT/CNPq INNT), Rio de Janeiro 21941-902, Rio de Janeiro, Brazil.
Ulrich H; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, São Paulo, Brazil.
Moura-Neto V; National Institute for Translational Neurosciences (INCT/CNPq INNT), Rio de Janeiro 21941-902, Rio de Janeiro, Brazil.; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, São Paulo, Brazil.; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Rio de Janeiro, Brazil.; Paulo Niemeyer State Institute of the Brain, Rio de Janeiro 20230-024, Rio de Janeiro, Brazil.
Lopes GPF; Department of Marine Biotechnology, Admiral Paulo Moreira Institute for Sea Studies (IEAPM), Arraial do Cabo 28930-000, Rio de Janeiro, Brazil.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador 40110-902, Bahia, Brazil.; National Institute for Translational Neurosciences (INCT/CNPq INNT), Rio de Janeiro 21941-902, Rio de Janeiro, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Jan 04; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 04.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative.
Autorzy:
da Silva SVS; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.
Barboza OM; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.
Souza JT; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
Soares ÉN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
Dos Santos CC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
Pacheco LV; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.; Gonçalo Moniz Institute, FIOCRUZ, Salvador 40296-710, BA, Brazil.
Santos IP; Gonçalo Moniz Institute, FIOCRUZ, Salvador 40296-710, BA, Brazil.
Magalhães TBDS; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.
Soares MBP; Gonçalo Moniz Institute, FIOCRUZ, Salvador 40296-710, BA, Brazil.; SENAI Institute of Innovation in Health Advanced Systems (CIMATEC ISI SAS), University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.
Guimarães ET; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.; Gonçalo Moniz Institute, FIOCRUZ, Salvador 40296-710, BA, Brazil.
Meira CS; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.; Gonçalo Moniz Institute, FIOCRUZ, Salvador 40296-710, BA, Brazil.; SENAI Institute of Innovation in Health Advanced Systems (CIMATEC ISI SAS), University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Federal University of Bahia, Salvador 40231-300, BA, Brazil.
de Santana LLB; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.
de Freitas Santos Júnior A; Department of Life Sciences, State University of Bahia (UNEB), Salvador 41150-000, BA, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 17; Vol. 26 (22). Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/chemical synthesis
Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/pharmacology
Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Antioxidants*/chemical synthesis
Antioxidants*/chemistry
Antioxidants*/pharmacology
Antiprotozoal Agents*/chemical synthesis
Antiprotozoal Agents*/chemistry
Antiprotozoal Agents*/pharmacology
Quercetin/*analogs & derivatives
Acetylation ; Animals ; HL-60 Cells ; Hep G2 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Quercetin/chemical synthesis ; Quercetin/chemistry ; Quercetin/pharmacology
Czasopismo naukowe
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Tytuł:
The Flavonoid Agathisflavone from Poincianella pyramidalis Prevents Aminochrome Neurotoxicity.
Autorzy:
Santos CC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
Muñoz P; Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Independencia, 1027, Santiago, Chile.
Almeida ÁMAN; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
de Lima David JP; Department of Medication, Faculty of Pharmacy, Federal University of Bahia, Salvador, Bahia, 40170-290, Brazil.
David JM; Department of General and Inorganic Chemistry, Institute of Chemistry, Federal University of Bahia, Salvador, Bahia, Brazil.
Lima Costa S; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil.
Segura-Aguilar J; Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Independencia, 1027, Santiago, Chile. .
Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, 40110-100, Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2020 Oct; Vol. 38 (3), pp. 579-584. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Biflavonoids/*pharmacology
Cell Death/*drug effects
Dopaminergic Neurons/*drug effects
Neurotoxicity Syndromes/*drug therapy
Humans ; Neuroprotection/drug effects ; Neurotoxins/pharmacology ; Parkinson Disease/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phytoestrogen Agathisflavone Ameliorates Neuroinflammation-Induced by LPS and IL-1β and Protects Neurons in Cocultures of Glia/Neurons.
Autorzy:
de Almeida MMA; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
Souza CDS; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.; INCT-Sheffield Institute of Translational Neuroscience (SITraN), The University of Sheffield, Sheffield S10 2HQ, UK.
Dourado NS; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
da Silva AB; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
Ferreira RS; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
David JM; Department of General and Inorganic Chemistry, Institute of Chemistry, Federal University of Bahia, Salvador-Bahia 40.170-115, Brazil.
David JP; Department of Medication, Faculty of Pharmacy, Federal University of Bahia, Salvador-Bahia 40.170-115, Brazil.
Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
da Silva VDA; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
Butt AM; School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth PO1 2DT, UK.
Costa SL; Laboratory of Neurochemistry and Cellular Biology, Department of Biophysics and Biochemistry, Institute of Health Sciences, Federal University of Bahia, Salvador-Bahia 40.110-100, Brazil.
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Źródło:
Biomolecules [Biomolecules] 2020 Apr 07; Vol. 10 (4). Date of Electronic Publication: 2020 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Biflavonoids/*pharmacology
Interleukin-1beta/*pharmacology
Lipopolysaccharides/*pharmacology
Neuroglia/*drug effects
Neurons/*drug effects
Phytoestrogens/*pharmacology
Anti-Inflammatory Agents/therapeutic use ; Biflavonoids/therapeutic use ; Coculture Techniques ; Humans ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/pathology ; Neuroglia/pathology ; Neurons/pathology ; Phytoestrogens/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
KM-34, a Novel Antioxidant Compound, Protects against 6-Hydroxydopamine-Induced Mitochondrial Damage and Neurotoxicity.
Autorzy:
Fonseca-Fonseca LA; Centro de Investigación y Desarrollo de Medicamentos, Ave 26, No. 1605 Boyeros y Puentes Grandes, CP 10600, Ciudad de la Habana, Cuba.
Nuñez-Figueredo Y; Centro de Investigación y Desarrollo de Medicamentos, Ave 26, No. 1605 Boyeros y Puentes Grandes, CP 10600, Ciudad de la Habana, Cuba.
Sánchez JR; Centro de Investigación y Desarrollo de Medicamentos, Ave 26, No. 1605 Boyeros y Puentes Grandes, CP 10600, Ciudad de la Habana, Cuba.
Guerra MW; Centro de Investigación y Desarrollo de Medicamentos, Ave 26, No. 1605 Boyeros y Puentes Grandes, CP 10600, Ciudad de la Habana, Cuba.
Ochoa-Rodríguez E; Laboratorio de Síntesis Orgánica. Departamento de Química Orgánica. Facultad de Química, Universidad de La Habana (Zapata s/n entre G y Carlitos Aguirre, Vedado, Plaza de la Revolución, CP 10400, Ciudad de la Habana, Cuba.
Verdecia-Reyes Y; Laboratorio de Síntesis Orgánica. Departamento de Química Orgánica. Facultad de Química, Universidad de La Habana (Zapata s/n entre G y Carlitos Aguirre, Vedado, Plaza de la Revolución, CP 10400, Ciudad de la Habana, Cuba.
Hernádez RD; Centro de Investigación y Desarrollo de Medicamentos, Ave 26, No. 1605 Boyeros y Puentes Grandes, CP 10600, Ciudad de la Habana, Cuba.
Menezes-Filho NJ; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil.
Costa TCS; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil.
de Santana WA; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil.
Oliveira JL; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil.
Segura-Aguilar J; Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Santiago, Chile.
da Silva VDA; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil.
Costa SL; Laboratório de Neuroquímica e Biologia Celular, Instituto de Ciências da Saúde, Universidade Federal da Bahia - UFBA, Av. Reitor Miguel Calmon s/n, Vale do Canela, Salvador, Bahia, CEP 41100-100, Brazil. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2019 Aug; Vol. 36 (2), pp. 279-291. Date of Electronic Publication: 2018 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*therapeutic use
Catechols/*therapeutic use
Mitochondria/*drug effects
Neuroprotective Agents/*therapeutic use
Oxidopamine/*toxicity
Parkinsonian Disorders/*prevention & control
Animals ; Antioxidants/pharmacology ; Catechols/pharmacology ; Dose-Response Relationship, Drug ; Male ; Mitochondria/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; PC12 Cells ; Parkinsonian Disorders/chemically induced ; Parkinsonian Disorders/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
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Tytuł:
Neurotoxicity of Prosopis juliflora: from Natural Poisoning to Mechanism of Action of Its Piperidine Alkaloids.
Autorzy:
da Silva VDA; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, 40110-100, Brazil. .
da Silva AMM; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, 40110-100, Brazil.
E Silva JHC; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, 40110-100, Brazil.
Costa SL; Laboratory of Neurochemistry and Cell Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, 40110-100, Brazil.
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Źródło:
Neurotoxicity research [Neurotox Res] 2018 Nov; Vol. 34 (4), pp. 878-888. Date of Electronic Publication: 2018 Jan 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurotoxins/*toxicity
Prosopis/*toxicity
Animals ; Humans ; Neurons/drug effects ; Neurotoxins/poisoning ; Piperidines/poisoning ; Piperidines/toxicity ; Prosopis/poisoning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of P2 Receptors as Modulators of Rat Eosinophil Recruitment in Allergic Inflammation.
Autorzy:
Alberto AV; Laboratório de Comunicação Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Faria RX; Laboratório de Comunicação Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
de Menezes JR; Laboratório de Neuroanatomia Celular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Surrage A; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
da Rocha NC; Laboratório de Comunicação Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Ferreira LG; Laboratório de Comunicação Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Frutuoso Vda S; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Martins MA; Laboratório de Inflamação, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Alves LA; Laboratório de Comunicação Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
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Źródło:
PloS one [PLoS One] 2016 Jan 19; Vol. 11 (1), pp. e0145392. Date of Electronic Publication: 2016 Jan 19 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemotaxis, Leukocyte/*immunology
Eosinophils/*immunology
Eosinophils/*metabolism
Hypersensitivity/*immunology
Hypersensitivity/*metabolism
Receptors, Purinergic P2/*metabolism
Action Potentials ; Animals ; Calcium/metabolism ; Disease Models, Animal ; Hypersensitivity/pathology ; Ions/metabolism ; Male ; Nucleotides/metabolism ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protease-inhibiting, molecular modeling and antimicrobial activities of extracts and constituents from Helichrysum foetidum and Helichrysum mechowianum (compositae).
Autorzy:
Malolo FA; Department of Pharmacy, University of Douala, Douala, P.O. Box 812, Cameroon.
Bissoue Nouga A; Department of Chemistry, University of Douala, Douala, P.O. Box 567 24157, Cameroon.
Kakam A; Department of Chemistry, University of Douala, Douala, P.O. Box 567 24157, Cameroon.
Franke K; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle (Saale), Germany.
Ngah L; Department of Pharmacy, University of Douala, Douala, P.O. Box 812, Cameroon.
Flausino O Jr; Química, Departamento de Química Orgânica, Núcleo de Bioensaio, Biossíntese e Ecofisiologia de Produtos Naturais-NuBBE, Universidade Estadual Paulista (UNESP) Instituto de Rua Prof. Francisco Degni s/n, Araraquara, São Paulo 14.800-900 Brazil.
Mpondo Mpondo E; Department of Pharmacy, University of Douala, Douala, P.O. Box 812, Cameroon.
Ntie-Kang F; Chemical and Bioactivity Information Centre, Department of Chemistry, University of Buea, P. O. Box 63, Buea, Cameroon.
Ndom JC; Department of Pharmacy, University of Douala, Douala, P.O. Box 812, Cameroon.
Bolzani Vda S; Química, Departamento de Química Orgânica, Núcleo de Bioensaio, Biossíntese e Ecofisiologia de Produtos Naturais-NuBBE, Universidade Estadual Paulista (UNESP) Instituto de Rua Prof. Francisco Degni s/n, Araraquara, São Paulo 14.800-900 Brazil.
Wessjohann L; Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle (Saale), Germany.
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Źródło:
Chemistry Central journal [Chem Cent J] 2015 May 30; Vol. 9, pp. 32. Date of Electronic Publication: 2015 May 30 (Print Publication: 2015).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
An Improved Method for P2X7R Antagonist Screening.
Autorzy:
Soares-Bezerra RJ; Laboratory of Cellular Communication, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Ferreira NC; Laboratory of Cellular Communication, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Alberto AV; Laboratory of Cellular Communication, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Bonavita AG; Laboratory of Integrated Research, Campus UFRJ-Macaé Professor Aloísio Teixeira, UFRJ, Rio de Janeiro, Brazil.
Fidalgo-Neto AA; Laboratory of Cellular Communication, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Calheiros AS; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Frutuoso Vda S; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
Alves LA; Laboratory of Cellular Communication, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil.
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Źródło:
PloS one [PLoS One] 2015 May 19; Vol. 10 (5), pp. e0123089. Date of Electronic Publication: 2015 May 19 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Purinergic P2X Receptor Antagonists/*pharmacology
Adenosine Triphosphate/metabolism ; Animals ; Cell Line ; High-Throughput Screening Assays ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bacteriophage-fused peptides for serodiagnosis of human strongyloidiasis.
Autorzy:
Feliciano ND; Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
Ribeiro Vda S; Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
Santos Fde A; Laboratório de Nanobiotecnologia, Instituto de Genética e Bioquímica, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
Fujimura PT; Laboratório de Nanobiotecnologia, Instituto de Genética e Bioquímica, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
Gonzaga HT; Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
Goulart LR; Laboratório de Nanobiotecnologia, Instituto de Genética e Bioquímica, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil; Department of Medical Microbiology and Immunology, University of California, Davis, Davis, California, United States of America.
Costa-Cruz JM; Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brasil.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 May 29; Vol. 8 (5), pp. e2792. Date of Electronic Publication: 2014 May 29 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Helminth*/immunology
Peptides*/immunology
Parasitology/*methods
Strongyloides stercoralis/*immunology
Strongyloidiasis/*diagnosis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Antibodies, Helminth/blood ; Bacteriophages ; Enzyme-Linked Immunosorbent Assay/methods ; Female ; Humans ; Immunoglobulin G/blood ; Male ; Middle Aged ; Peptide Library ; Sensitivity and Specificity ; Strongyloides stercoralis/chemistry ; Strongyloidiasis/immunology ; Young Adult
Czasopismo naukowe
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