- Tytuł:
- Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.
- Autorzy:
-
Seyres D; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK. .; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. .; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK. .
Cabassi A; MRC Biostatistics Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Lambourne JJ; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.
Burden F; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.
Farrow S; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.
McKinney H; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Batista J; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Kempster C; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Pietzner M; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Slingsby O; Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Cao TH; Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Quinn PA; Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Stefanucci L; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.; British Heart Foundation Centre of Excellence, Cambridge Biomedical Campus, Cambridge, UK.Sims MC ; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.; Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals NHS Foundation Trust, NIHR Oxford Biomedical Research Centre, Oxford, UK.
Rehnstrom K; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Adams CL; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
Frary A; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Ergüener B; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Kreuzhuber R; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Mocciaro G; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, The Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
D'Amore S; Addenbrooke's Hospital, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.; National Cancer Research Center, IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco, 65, 70124, Bari, Italy.
Koulman A; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; MRC Elsie Widdowson Laboratory, Cambridge, UK.; National Institute for Health Research Biomedical Research Centres Core Nutritional Biomarker Laboratory, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.; National Institute for Health Research Biomedical Research Centres Core Metabolomics and Lipidomics Laboratory, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Grassi L; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.
Griffin JL; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, The Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Ng LL; Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Park A; Addenbrooke's Hospital, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Savage DB; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.
Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Downes K; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; East Midlands and East of England Genomic Laboratory Hub, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Allison M; Addenbrooke's Hospital, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Vacca M; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, UK.; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, The Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Kirk PDW; MRC Biostatistics Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. .; Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge Biomedical Campus, Puddicombe Way, Cambridge, CB2 0AW, UK. .
Frontini M; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. .; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK. .; British Heart Foundation Centre of Excellence, Cambridge Biomedical Campus, Cambridge, UK. .; Institute of Biomedical & Clinical Science, College of Medicine and Health, University of Exeter Medical School, RILD Building, Barrack Road, Exeter, EX2 5DW, UK. . - Pokaż więcej
- Źródło:
- Clinical epigenetics [Clin Epigenetics] 2022 Mar 12; Vol. 14 (1), pp. 39. Date of Electronic Publication: 2022 Mar 12.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Lipodystrophy*
Metabolic Syndrome*/genetics
Obesity, Morbid*/surgery
DNA Methylation ; Epigenesis, Genetic ; Humans ; Phenotype
Czasopismo naukowe