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Wyszukujesz frazę ""Site-Specific DNA-Methyltransferase \(Adenine-Specific\)"" wg kryterium: Temat


Tytuł :
Contribution of DNA adenine methylation to gene expression heterogeneity in Salmonella enterica.
Autorzy :
Sánchez-Romero MA; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, Seville 41080, Spain.
Olivenza DR; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, Seville 41080, Spain.
Gutiérrez G; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, Seville 41080, Spain.
Casadesús J; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, Seville 41080, Spain.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11857-11867.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Gene Expression Regulation, Bacterial*
Bacterial Proteins/*genetics
Salmonella enterica/*genetics
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*genetics
Transcription Factors/*genetics
Adenine/metabolism ; Bacterial Proteins/metabolism ; Computational Biology/methods ; Genetic Heterogeneity ; Genetic Loci ; Genotype ; Phenotype ; Salmonella enterica/metabolism ; Single-Cell Analysis/methods ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine modifications at non-palindromic recognition sites in Bacillus subtilis.
Autorzy :
Nye TM; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
van Gijtenbeek LA; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
Stevens AG; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
Schroeder JW; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
Randall JR; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
Matthews LA; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
Simmons LA; Department of Molecular, Cellular, and Developmental Biology University of Michigan, Ann Arbor, MI 48109-1055, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 04; Vol. 48 (10), pp. 5332-5348.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adenosine/*analogs & derivatives
Bacillus subtilis/*enzymology
Bacillus subtilis/*genetics
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Adenosine/analysis ; Adenosine/metabolism ; Bacillus subtilis/metabolism ; Bacterial Proteins/metabolism ; Chromosomes, Bacterial ; DNA Methylation ; DNA Restriction-Modification Enzymes ; Epigenesis, Genetic ; Gene Expression Regulation, Bacterial ; Genome, Bacterial ; Promoter Regions, Genetic ; Repressor Proteins/metabolism ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/physiology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Fur-Dam Regulatory Interplay at an Internal Promoter of the Enteroaggregative Escherichia coli Type VI Secretion sci1 Gene Cluster.
Autorzy :
Brunet YR; Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM), Institut de Microbiologie de la Méditerranée (IMM), CNRS-Aix-Marseille Université UMR7255, Marseille, France.
Bernard CS; Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM), Institut de Microbiologie de la Méditerranée (IMM), CNRS-Aix-Marseille Université UMR7255, Marseille, France.
Cascales E; Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM), Institut de Microbiologie de la Méditerranée (IMM), CNRS-Aix-Marseille Université UMR7255, Marseille, France .
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Źródło :
Journal of bacteriology [J Bacteriol] 2020 Apr 27; Vol. 202 (10). Date of Electronic Publication: 2020 Apr 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Multigene Family*
Bacterial Proteins/*metabolism
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
Repressor Proteins/*metabolism
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Type VI Secretion Systems/*metabolism
Bacterial Proteins/genetics ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Promoter Regions, Genetic ; Repressor Proteins/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Type VI Secretion Systems/genetics
Czasopismo naukowe
Tytuł :
Tetramerization at Low pH Licenses DNA Methylation Activity of M.HpyAXI in the Presence of Acid Stress.
Autorzy :
Narayanan N; Laboratory of Genomic Integrity & Evolution, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad 121001, Haryana, India; Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Banerjee A; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka, India.
Jain D; Transcription Regulation Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad 121 001, Haryana (NCR Delhi), India.
Kulkarni DS; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka, India.
Sharma R; Laboratory of Genomic Integrity & Evolution, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad 121001, Haryana, India.
Nirwal S; Laboratory of Genomic Integrity & Evolution, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad 121001, Haryana, India.
Rao DN; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, Karnataka, India; Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore 560064, Karnataka, India.
Nair DT; Laboratory of Genomic Integrity & Evolution, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad 121001, Haryana, India. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2020 Jan 17; Vol. 432 (2), pp. 324-342. Date of Electronic Publication: 2019 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation/*genetics
Helicobacter Infections/*genetics
Helicobacter pylori/*enzymology
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*genetics
Acids/metabolism ; Adenine/chemistry ; Adenine/metabolism ; Amino Acid Sequence/genetics ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Helicobacter Infections/enzymology ; Helicobacter Infections/microbiology ; Helicobacter pylori/pathogenicity ; Humans ; Hydrogen-Ion Concentration ; Kinetics ; Protein Multimerization/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry ; Stress, Physiological/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł :
The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site.
Autorzy :
Horton JR; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Woodcock CB; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Opot SB; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Reich NO; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA.
Zhang X; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. .
Cheng X; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. .
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Źródło :
Nature communications [Nat Commun] 2019 Oct 10; Vol. 10 (1), pp. 4600. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Caulobacter crescentus/*enzymology
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Crystallography, X-Ray ; DNA/chemistry ; DNA/metabolism ; Models, Molecular ; Protein Conformation ; Protein Domains ; Protein Multimerization ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics
Czasopismo naukowe
Tytuł :
Label-free and immobilization-free photoelectrochemical biosensing strategy using methylene blue in homogeneous solution as signal probe for facile DNA methyltransferase activity assay.
Autorzy :
Hou T; College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, PR China.
Xu N; College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, PR China.
Wang W; College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, PR China.
Ge L; College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, PR China.
Li F; College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, PR China. Electronic address: .
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2019 Sep 15; Vol. 141, pp. 111395. Date of Electronic Publication: 2019 Jun 05.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques/*instrumentation
Intercalating Agents/*chemistry
Methylene Blue/*chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*blood
DNA Methylation/drug effects ; Electrochemical Techniques/instrumentation ; Electrodes ; Enzyme Assays/instrumentation ; Equipment Design ; Humans ; Light ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/analysis ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/antagonists & inhibitors ; Solutions ; Tin Compounds/chemistry
Czasopismo naukowe
Tytuł :
The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells.
Autorzy :
Leetsi L; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Õunap K; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Abroi A; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Kurg R; Institute of Technology, University of Tartu, 50411 Tartu, Estonia. .
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Źródło :
Biomolecules [Biomolecules] 2019 Aug 28; Vol. 9 (9). Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Methyltransferases/*metabolism
Protein Isoforms/*metabolism
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Alternative Splicing/genetics ; Alternative Splicing/physiology ; Cell Line, Tumor ; HeLa Cells ; Humans ; Leupeptins/pharmacology ; Methyltransferases/chemistry ; Methyltransferases/genetics ; Proteasome Endopeptidase Complex/drug effects ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding/drug effects ; Protein Isoforms/genetics ; Protein Processing, Post-Translational/drug effects ; Protein Stability/drug effects ; RNA Interference ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics
Czasopismo naukowe
Tytuł :
Highly selective ratiometric electrogenerated chemiluminescence assay of DNA methyltransferase activity via polyaniline and anti-fouling peptide modified electrode.
Autorzy :
Li Y; Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China.
Wang L; Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China.
Ding C; Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China. Electronic address: .
Luo X; Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, PR China. Electronic address: .
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2019 Oct 01; Vol. 142, pp. 111553. Date of Electronic Publication: 2019 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Aniline Compounds/*chemistry
Biosensing Techniques/*methods
Luminescent Measurements/*methods
Peptides/*chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*analysis
Animals ; Biofouling/prevention & control ; Cattle ; Electrodes ; Enzyme Assays/methods ; HeLa Cells ; Humans ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/blood
Czasopismo naukowe
Tytuł :
Trifunctional integrated DNA-based universal sensing platform for detection of diverse biomolecules in one-pot isothermal exponential amplification mode.
Autorzy :
Cui YX; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. (Tianjin), Tianjin, 300071, P. R. China.
Feng XN; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. .
Li XY; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. .
Zhang YP; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. .
Tang AN; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. .
Kong DM; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, P. R. China. (Tianjin), Tianjin, 300071, P. R. China.
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2019 Jul 07; Vol. 55 (53), pp. 7603-7606. Date of Electronic Publication: 2019 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques*
Nucleic Acid Amplification Techniques*
Temperature*
DNA/*chemistry
Polynucleotide 5'-Hydroxyl-Kinase/*analysis
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*analysis
HeLa Cells ; Humans ; Polynucleotide 5'-Hydroxyl-Kinase/genetics ; Polynucleotide 5'-Hydroxyl-Kinase/metabolism ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.
Autorzy :
Metzger E; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Wang S; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Urban S; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Willmann D; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Schmidt A; BioMedical Center and Center of Integrated Protein Sciences (CIPSM), Ludwig-Maximilians-University of Munich, Planegg-Martinsried, Germany.
Offermann A; Pathologie des Universitätsklinikums Schleswig-Holstein, Campus Lübeck und des Forschungszentrums Borstel, Leibniz Lungenzentrum, Lübeck und Borstel, Germany.
Allen A; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Sum M; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Obier N; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Cottard F; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Ulferts S; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Preca BT; Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
Hermann B; Institut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Maurer J; Department of Obstetrics and Gynecology, University Hospital Aachen (UKA), Aachen, Germany.
Greschik H; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Hornung V; Gene Center and Department of Biochemistry, Ludwig-Maximilians-University of Munich, Munich, Germany.
Einsle O; Institut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Perner S; Pathologie des Universitätsklinikums Schleswig-Holstein, Campus Lübeck und des Forschungszentrums Borstel, Leibniz Lungenzentrum, Lübeck und Borstel, Germany.
Imhof A; BioMedical Center and Center of Integrated Protein Sciences (CIPSM), Ludwig-Maximilians-University of Munich, Planegg-Martinsried, Germany.
Jung M; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Schüle R; Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg, Germany. .; Deutsches Konsortium für Translationale Krebsforschung, Standort Freiburg, Freiburg, Germany. .; BIOSS Centre of Biological Signalling Studies, Albert-Ludwigs-University Freiburg, Freiburg, Germany. .; K-metics GmbH, Freiburg, Germany. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2019 May; Vol. 26 (5), pp. 361-371. Date of Electronic Publication: 2019 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*physiology
Histones/*metabolism
Lysine/*metabolism
Prostatic Neoplasms, Castration-Resistant/*pathology
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Cell Line, Tumor ; Dimerization ; Histones/chemistry ; Humans ; Male ; Methylation ; Methyltransferases/chemistry ; Methyltransferases/metabolism ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/physiology
Czasopismo naukowe
Tytuł :
Dam mutants provide improved sensitivity and spatial resolution for profiling transcription factor binding.
Autorzy :
Szczesnik T; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
Ho JWK; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China.
Sherwood R; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. .; Hubrecht Institute, 3584 CT, Utrecht, The Netherlands. .
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Źródło :
Epigenetics & chromatin [Epigenetics Chromatin] 2019 Jun 13; Vol. 12 (1), pp. 36. Date of Electronic Publication: 2019 Jun 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Sequence Analysis, DNA/*methods
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Transcription Factor 7-Like 2 Protein/*metabolism
Animals ; Binding Sites ; Chromatin/genetics ; DNA/metabolism ; DNA Methylation/genetics ; DNA-Binding Proteins/metabolism ; Embryonic Stem Cells ; Genomics/methods ; Mice ; Mutation ; Protein Binding ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Transcription Factor 7-Like 2 Protein/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization.
Autorzy :
Beh LY; Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY 10032, USA; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Debelouchina GT; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Clay DM; Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY 10032, USA.
Thompson RE; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Lindblad KA; Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY 10032, USA.
Hutton ER; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Bracht JR; Department of Biology, American University, Washington, DC 20016, USA.
Sebra RP; Icahn Institute and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Muir TW; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA. Electronic address: .
Landweber LF; Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY 10032, USA. Electronic address: .
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Źródło :
Cell [Cell] 2019 Jun 13; Vol. 177 (7), pp. 1781-1796.e25. Date of Electronic Publication: 2019 May 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Multienzyme Complexes/*metabolism
Nucleosomes/*enzymology
Oxytricha/*enzymology
Protozoan Proteins/*metabolism
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Tetrahymena thermophila/*enzymology
Multienzyme Complexes/genetics ; Nucleosomes/genetics ; Oxytricha/genetics ; Protozoan Proteins/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Tetrahymena thermophila/genetics
Czasopismo naukowe
Tytuł :
A dual-response biosensor for electrochemical and glucometer detection of DNA methyltransferase activity based on functionalized metal-organic framework amplification.
Autorzy :
Chen Y; College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, PR China.
Meng XZ; College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, PR China.
Gu HW; College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, PR China.
Yi HC; College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, PR China. Electronic address: .
Sun WY; College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, PR China; Coordination Chemistry Institute, State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing National Laboratory of Microstructures, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, 210023, PR China. Electronic address: .
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2019 Jun 01; Vol. 134, pp. 117-122. Date of Electronic Publication: 2019 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques/*methods
Enzyme Assays/*methods
Metal-Organic Frameworks/*chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*analysis
Blood Glucose Self-Monitoring/methods ; Copper/chemistry ; Enzymes, Immobilized/chemistry ; Glucose/analysis ; Gold/chemistry ; Humans ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism ; beta-Fructofuranosidase/chemistry
Czasopismo naukowe
Tytuł :
Perylene-Based Photoactive Material as a Double-Stranded DNA Intercalating Probe for Ultrasensitive Photoelectrochemical Biosensing.
Autorzy :
Li H; College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , People's Republic of China.
Wang J; College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , People's Republic of China.
Wang X; College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , People's Republic of China.
Lin H; College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , People's Republic of China.
Li F; College of Chemistry and Pharmaceutical Sciences , Qingdao Agricultural University , Qingdao 266109 , People's Republic of China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2019 May 08; Vol. 11 (18), pp. 16958-16964. Date of Electronic Publication: 2019 Apr 25.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques*
DNA/*chemistry
Intercalating Agents/*chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*isolation & purification
DNA, Single-Stranded/radiation effects ; Electrochemical Techniques/methods ; Humans ; Light ; Perylene/chemistry ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry ; Tin Compounds/chemistry
Czasopismo naukowe
Tytuł :
Multiple sealed primers-mediated rolling circle amplification strategy for sensitive and specific detection of DNA methyltransferase activity.
Autorzy :
Xu X; Key Laboratory for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, 250100 Jinan, PR China.
Wang L; School of Pharmaceutical Sciences, Shandong University, 250012 Jinan, PR China.
Li X; Department of Chemistry, Liaocheng University, Liaocheng 252059, PR China.
Cui W; Key Laboratory for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, 250100 Jinan, PR China.
Jiang W; Key Laboratory for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University, 250100 Jinan, PR China. Electronic address: .
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Źródło :
Talanta [Talanta] 2019 Mar 01; Vol. 194, pp. 282-288. Date of Electronic Publication: 2018 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Limit of Detection*
Biosensing Techniques/*methods
DNA Primers/*genetics
Nucleic Acid Amplification Techniques/*methods
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Humans ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/antagonists & inhibitors ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/blood
Czasopismo naukowe
Tytuł :
A microchip electrophoretic assay for DNA methyltransferase activity based on methylation-sensitive endonuclease DpnⅡ.
Autorzy :
Zhang Y; School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P. R. China.
Zhang Y; School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P. R. China.
Zhu L; School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P. R. China.
He P; School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P. R. China.
Wang Q; School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P. R. China.
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Źródło :
Electrophoresis [Electrophoresis] 2019 Feb; Vol. 40 (3), pp. 425-430. Date of Electronic Publication: 2018 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Site-Specific DNA-Methyltransferase (Adenine-Specific)*/analysis
Site-Specific DNA-Methyltransferase (Adenine-Specific)*/metabolism
DNA Methylation/*physiology
Deoxyribonucleases, Type II Site-Specific/*metabolism
Electrophoresis, Microchip/*methods
Biosensing Techniques/methods ; DNA/analysis ; DNA/chemistry ; DNA/metabolism ; Humans ; Limit of Detection
Czasopismo naukowe
Tytuł :
Simultaneous quantification of protein-DNA interactions and transcriptomes in single cells with scDam&T-seq.
Autorzy :
Markodimitraki CM; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Rang FJ; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Rooijers K; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
de Vries SS; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Chialastri A; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA.; Center for Bioengineering, University of California Santa Barbara, Santa Barbara, CA, USA.
de Luca KL; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Lochs SJA; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Mooijman D; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Dey SS; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, USA. .; Center for Bioengineering, University of California Santa Barbara, Santa Barbara, CA, USA. .
Kind J; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. .
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Źródło :
Nature protocols [Nat Protoc] 2020 Jun; Vol. 15 (6), pp. 1922-1953. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA/*metabolism
Gene Expression Profiling/*methods
Genomics/*methods
Proteins/*metabolism
Animals ; Cell Line ; Cell Line, Tumor ; DNA/genetics ; DNA Methylation ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Humans ; Mice ; Protein Binding ; Proteins/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Sequence Analysis, DNA/methods ; Single-Cell Analysis/methods ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Single-molecule regulatory architectures captured by chromatin fiber sequencing.
Autorzy :
Stergachis AB; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. .
Debo BM; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Haugen E; Altius Institute for Biomedical Sciences, Seattle, WA, USA.
Churchman LS; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Stamatoyannopoulos JA; Altius Institute for Biomedical Sciences, Seattle, WA, USA. .; Departments of Genome Sciences and Medicine, University of Washington, Seattle, WA, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Jun 26; Vol. 368 (6498), pp. 1449-1454.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chromatin Assembly and Disassembly*
Gene Expression Regulation*
High-Throughput Nucleotide Sequencing*
Chromatin/*chemistry
Single Molecule Imaging/*methods
Animals ; DNA/chemistry ; DNA/genetics ; Drosophila melanogaster ; Humans ; K562 Cells ; Nucleosomes/chemistry ; Promoter Regions, Genetic ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry ; Transcription Factors/chemistry
Czasopismo naukowe
Tytuł :
The highly specific, cell cycle-regulated methyltransferase from Caulobacter crescentus relies on a novel DNA recognition mechanism.
Autorzy :
Reich NO; From the Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106 .
Dang E; From the Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106.
Kurnik M; From the Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106.
Pathuri S; From the Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106.
Woodcock CB; From the Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2018 Dec 07; Vol. 293 (49), pp. 19038-19046. Date of Electronic Publication: 2018 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins/*metabolism
Caulobacter crescentus/*enzymology
DNA, Bacterial/*metabolism
Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
Agrobacterium tumefaciens/enzymology ; Amino Acid Sequence ; Bacterial Proteins/chemistry ; Base Pair Mismatch ; Brucella abortus/enzymology ; Catalytic Domain ; DNA Methylation ; DNA, Bacterial/genetics ; Protein Domains ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/chemistry
Czasopismo naukowe

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