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Wyszukujesz frazę ""Sivalingam VN"" wg kryterium: Autor


Wyświetlanie 1-17 z 17
Tytuł :
Metabolomic Biomarkers for the Detection of Obesity-Driven Endometrial Cancer.
Autorzy :
Njoku K; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.; Stoller Biomarker Discovery Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
Campbell AE; Stoller Biomarker Discovery Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
Geary B; Stoller Biomarker Discovery Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
MacKintosh ML; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Derbyshire AE; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Pierce A; Wolfson Molecular Imaging Centre, Division of Cancer Sciences, University of Manchester, Palatine Road, Manchester M20 3LJ, UK.
Whetton AD; Stoller Biomarker Discovery Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.; Wolfson Molecular Imaging Centre, Division of Cancer Sciences, University of Manchester, Palatine Road, Manchester M20 3LJ, UK.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 5th Floor Research, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
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Źródło :
Cancers [Cancers (Basel)] 2021 Feb 10; Vol. 13 (4). Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study.
Autorzy :
Ryan NAJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Division of Evolution and Genomic Medicine, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
McMahon R; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Tobi S; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Snowsill T; Health Economics Group, University of Exeter Medical School, University of Exeter, Exeter, Devon, United Kingdom.
Esquibel S; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Wallace AJ; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Bunstone S; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Bowers N; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Mosneag IE; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
O'Flynn H; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Ramchander NC; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Frayling IM; Inherited Tumour Syndromes Research Group, Institute of Cancer & Genetics, Cardiff University, Cardiff, United Kingdom.
Bolton J; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
McVey RJ; Department of Pathology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Evans DG; Division of Evolution and Genomic Medicine, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Manchester Centre for Genomic Medicine, North-West Genomics Laboratory Hub, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.; Department of Obstetrics and Gynaecology, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
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Źródło :
PLoS medicine [PLoS Med] 2020 Sep 17; Vol. 17 (9), pp. e1003263. Date of Electronic Publication: 2020 Sep 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis
Early Detection of Cancer/*methods
Endometrial Neoplasms/*genetics
Adult ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Cross-Sectional Studies ; DNA Methylation/genetics ; DNA Mismatch Repair/genetics ; Endometrial Neoplasms/diagnosis ; Female ; Genetic Testing/methods ; Humans ; Immunohistochemistry ; Mass Screening/methods ; Microsatellite Instability ; Middle Aged ; Prospective Studies ; Sensitivity and Specificity ; United Kingdom
Czasopismo naukowe
Tytuł :
Detecting Endometrial Cancer by Blood Spectroscopy: A Diagnostic Cross-Sectional Study.
Autorzy :
Paraskevaidi M; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.; Department of Metabolism, Institute of Reproductive and Developmental Biology, Digestion and Reproduction & Surgery and Cancer, Imperial College London, London W12 0HS, UK.
Morais CLM; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Ashton KM; Pathology Department, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
Stringfellow HF; Pathology Department, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
McVey RJ; Pathology Department, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Ryan NAJ; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
O'Flynn H; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Sivalingam VN; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Kitson SJ; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
MacKintosh ML; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Derbyshire AE; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Pow C; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Raglan O; Department of Metabolism, Institute of Reproductive and Developmental Biology, Digestion and Reproduction & Surgery and Cancer, Imperial College London, London W12 0HS, UK.
Lima KMG; Department of Chemistry, Biological Chemistry and Chemometrics, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.
Kyrgiou M; Department of Metabolism, Institute of Reproductive and Developmental Biology, Digestion and Reproduction & Surgery and Cancer, Imperial College London, London W12 0HS, UK.; West London Gynaecological Cancer Centre, Queen Charlotte's & Chelsea-Hammersmith Hospital, Imperial Healthcare NHS Trust, London W12 0HS, UK.
Martin-Hirsch PL; Department of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
Martin FL; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Crosbie EJ; Division of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
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Źródło :
Cancers [Cancers (Basel)] 2020 May 16; Vol. 12 (5). Date of Electronic Publication: 2020 May 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin.
Autorzy :
Sivalingam VN; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Latif A; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Kitson S; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
McVey R; Department of Histopathology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Finegan KG; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Marshall K; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Lisanti MP; School of Environmental & Life Sciences, University of Salford, Salford, UK.
Sotgia F; School of Environmental & Life Sciences, University of Salford, Salford, UK.
Stratford IJ; Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Crosbie EJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK. .; Department of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. .
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Źródło :
British journal of cancer [Br J Cancer] 2020 Jan; Vol. 122 (1), pp. 62-71. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia/*drug effects
Cytostatic Agents/*therapeutic use
Endometrial Neoplasms/*drug therapy
Endometrial Neoplasms/*metabolism
Hyperglycemia/*metabolism
Hypoglycemic Agents/*therapeutic use
Metformin/*therapeutic use
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Carbonic Anhydrase IX/genetics ; Carbonic Anhydrase IX/metabolism ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cytostatic Agents/administration & dosage ; Endometrial Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Ki-67 Antigen/metabolism ; Metformin/administration & dosage ; Metformin/adverse effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Preoperative Care/methods ; Signal Transduction/drug effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Optimization of Window Study Endpoints in Endometrial Cancer.
Autorzy :
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.
Maskell Z; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.
Shaw J; Department of Histopathology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom.; Department of Obstetrics and Gynaecology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
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Źródło :
Frontiers in oncology [Front Oncol] 2019 May 29; Vol. 9, pp. 428. Date of Electronic Publication: 2019 May 29 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
PRE-surgical Metformin In Uterine Malignancy (PREMIUM): a Multi-Center, Randomized Double-Blind, Placebo-Controlled Phase III Trial.
Autorzy :
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Maskell Z; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Allen JL; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Ali S; Department of Obstetrics and Gynaecology, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.; Department of Obstetrics and Gynaecology, Pennine Acute Hospitals NHS Trust, Manchester, United Kingdom.
Burns S; Department of Obstetrics and Gynaecology, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, United Kingdom.
Gilmour K; Department of Obstetrics and Gynaecology, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, United Kingdom.
Latheef R; Department of Obstetrics and Gynaecology, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, United Kingdom.
Slade RJ; Department of Gynaecological Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Pemberton PW; Department of Clinical Biochemistry, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Shaw J; Department of Histopathology, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Ryder WD; Manchester Academic Health Science Centre-Clinical Trials Coordination Unit, Manchester, United Kingdom.
Kitchener HC; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, United Kingdom. .; Department of Obstetrics and Gynaecology, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Apr 15; Vol. 25 (8), pp. 2424-2432. Date of Electronic Publication: 2018 Dec 18.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Preoperative Care*
Hypoglycemic Agents/*administration & dosage
Metformin/*administration & dosage
Uterine Neoplasms/*therapy
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Cell Proliferation/drug effects ; Female ; Humans ; Hypoglycemic Agents/adverse effects ; Insulin/metabolism ; Metformin/adverse effects ; Middle Aged ; Neoplasm Staging ; Phosphatidylinositol 3-Kinases/metabolism ; Prognosis ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Treatment Outcome ; Uterine Neoplasms/diagnosis ; Uterine Neoplasms/metabolism ; Uterine Neoplasms/mortality
Czasopismo naukowe
Tytuł :
Declining hysterectomy prevalence and the estimated impact on uterine cancer incidence in Scotland.
Autorzy :
Ruiz de Azua Unzurrunzaga G; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Brewster DH; Scottish Cancer Registry, NHS National Services Scotland, Gyle Square, 1 South Gyle Crescent, Edinburgh EH12 9EB, United Kingdom.
Wild SH; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, United Kingdom. Electronic address: vanitha.sivalingam@manchester.ac.uk.
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Źródło :
Cancer epidemiology [Cancer Epidemiol] 2019 Apr; Vol. 59, pp. 227-231. Date of Electronic Publication: 2019 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hysterectomy/*statistics & numerical data
Treatment Refusal/*statistics & numerical data
Uterine Neoplasms/*epidemiology
Uterine Neoplasms/*surgery
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Incidence ; Middle Aged ; Prevalence ; Scotland/epidemiology
Czasopismo naukowe
Tytuł :
High prevalence of metabolic syndrome in women newly diagnosed with endometrial cancer.
Autorzy :
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.
Lindsay J; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.
Rutter MK; Division of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.; Manchester Diabetes Centre, Hathersage Rd, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 0JE, UK.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, UK.; Department of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.
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Źródło :
Gynecologic oncology reports [Gynecol Oncol Rep] 2018 Aug 23; Vol. 26, pp. 109-110. Date of Electronic Publication: 2018 Aug 23 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: A prospective case control study.
Autorzy :
Kitson SJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom.
Lindsay J; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom.
Sivalingam VN; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom.
Lunt M; Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester M13 9PL, United Kingdom.
Ryan NAJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom.
Edmondson RJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom; Department of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Rutter MK; Division of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, United Kingdom; Manchester Diabetes Centre, 193 Hathersage Road, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 0JE, United Kingdom.
Crosbie EJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom; Department of Obstetrics and Gynaecology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom. Electronic address: .
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Źródło :
Gynecologic oncology [Gynecol Oncol] 2018 Jan; Vol. 148 (1), pp. 154-160. Date of Electronic Publication: 2017 Nov 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiovascular Diseases/*epidemiology
Endometrial Neoplasms/*epidemiology
Adult ; Case-Control Studies ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/physiopathology ; England/epidemiology ; Female ; Humans ; Prospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer.
Autorzy :
Latif A; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Chadwick AL; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.
Kitson SJ; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.
Gregson HJ; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.
Sivalingam VN; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.
Bolton J; Department of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
McVey RJ; Department of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Roberts SA; Division of Population Health, Health Services Research and Primary Care, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Marshall KM; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Williams KJ; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Stratford IJ; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Crosbie EJ; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Level 5 - Research, St Mary's Hospital, Oxford Road, Manchester, M13 9WL UK.; Department of Obstetrics and Gynaecology, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
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Źródło :
BMC clinical pathology [BMC Clin Pathol] 2017 Dec 28; Vol. 17, pp. 27. Date of Electronic Publication: 2017 Dec 28 (Print Publication: 2017).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Corrigendum: Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome.
Autorzy :
Atiomo W
Shafiee MN
Chapman C
Metzler VM
Abouzeid J
Latif A
Chadwick A
Kitson S
Sivalingam VN
Stratford IJ
Rutland CS
Persson JL
Ødum N
Fuentes-Utrilla P
Jeyapalan JN
Heery DM
Crosbie EJ
Mongan NP
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Źródło :
Clinical endocrinology [Clin Endocrinol (Oxf)] 2017 Dec; Vol. 87 (6), pp. 886.
Typ publikacji :
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł :
Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome.
Autorzy :
Atiomo W; Faculty of Medicine and Health Sciences, Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Queen's Medical Centre, Nottingham University Hospital, Nottingham, UK.
Shafiee MN; Faculty of Medicine and Health Sciences, Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Queen's Medical Centre, Nottingham University Hospital, Nottingham, UK.; Faculty of Medicine, Department Obstetrics and Gynaecology, UKM Medical Centre, Cheras, Kuala Lumpur, Malaysia.
Chapman C; Faculty of Medicine and Health Sciences, Division of Obstetrics and Gynaecology and Child Health, School of Medicine, Queen's Medical Centre, Nottingham University Hospital, Nottingham, UK.
Metzler VM; Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Abouzeid J; Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Latif A; Faculty of Biology, Medicine and Health, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester, UK.
Chadwick A; Faculty of Biology, Division of Molecular & Clinical Cancer Sciences, Medicine and Health, University of Manchester, Manchester, UK.
Kitson S; Faculty of Biology, Division of Molecular & Clinical Cancer Sciences, Medicine and Health, University of Manchester, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Manchester School of Pharmacy, University of Manchester, Manchester, UK.
Sivalingam VN; Faculty of Biology, Division of Molecular & Clinical Cancer Sciences, Medicine and Health, University of Manchester, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Manchester School of Pharmacy, University of Manchester, Manchester, UK.
Stratford IJ; Faculty of Biology, Medicine and Health, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester, UK.
Rutland CS; Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Persson JL; Clinical Research Center, Lund University, Malmö, Sweden.; Department of Molecular Bology, Umeå University, Umeå, Sweden.
Ødum N; Department of Immunology and Microbiology, University of Copenhagen, Kobenhavn, Denmark.
Fuentes-Utrilla P; Edinburgh Genomics, University of Edinburgh, Edinburgh, UK.
Jeyapalan JN; Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Heery DM; School of Pharmacy, University of Nottingham, Nottingham, UK.
Crosbie EJ; Faculty of Biology, Division of Molecular & Clinical Cancer Sciences, Medicine and Health, University of Manchester, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Manchester School of Pharmacy, University of Manchester, Manchester, UK.
Mongan NP; Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
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Źródło :
Clinical endocrinology [Clin Endocrinol (Oxf)] 2017 Nov; Vol. 87 (5), pp. 557-565. Date of Electronic Publication: 2017 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Endometrial Neoplasms/*metabolism
Endometrium/*metabolism
NAD(P)H Dehydrogenase (Quinone)/*metabolism
Polycystic Ovary Syndrome/*metabolism
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Cross-Sectional Studies ; Endometrial Neoplasms/enzymology ; Endometrium/enzymology ; Female ; Gene Expression ; Humans ; Immunohistochemistry ; Middle Aged ; Polycystic Ovary Syndrome/enzymology ; Young Adult
Czasopismo naukowe
Tytuł :
Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.
Autorzy :
Kitson S; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Sivalingam VN; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Bolton J; Department of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
McVey R; Department of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Nickkho-Amiry M; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Powell ME; Department of Clinical Oncology, Barts Health NHS Trust, London, UK.
Leary A; INSERM U981 and Department of Medicine, Gynecology Unit, Gustave Roussy, Villejuif, France.
Nijman HW; Department of Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Nout RA; Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Bosse T; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Renehan AG; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.
Kitchener HC; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.
Edmondson RJ; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Crosbie EJ; Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK.; Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
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Źródło :
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2017 Mar; Vol. 30 (3), pp. 459-468. Date of Electronic Publication: 2016 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Endometrioid/*pathology
Endometrial Neoplasms/*pathology
Ki-67 Antigen/*metabolism
Carcinoma, Endometrioid/metabolism ; Endometrial Neoplasms/metabolism ; Female ; Humans ; Immunohistochemistry ; Observer Variation ; Prognosis
Czasopismo naukowe
Tytuł :
Measuring the biological effect of presurgical metformin treatment in endometrial cancer.
Autorzy :
Sivalingam VN; Gynaecological Oncology Research Group, Institute of Cancer Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Kitson S; Gynaecological Oncology Research Group, Institute of Cancer Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
McVey R; Department of Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Roberts C; Centre for Biostatistics, Institute of Population Health, University of Manchester, Manchester, UK.
Pemberton P; Clinical Biochemistry Department, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Gilmour K; Obstetrics and Gynaecology Department, Tameside General Hospital, Tameside, UK.
Ali S; Obstetrics and Gynaecology Department, The Royal Oldham Hospital, Pennine Acute Hospitals NHS Trust, Oldham, UK.
Renehan AG; Cancer Studies and Surgery Research Group, Institute of Cancer Sciences, University of Manchester, Manchester, UK.
Kitchener HC; Gynaecological Oncology Research Group, Institute of Cancer Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Crosbie EJ; Gynaecological Oncology Research Group, Institute of Cancer Sciences, University of Manchester, St Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
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Źródło :
British journal of cancer [Br J Cancer] 2016 Feb 02; Vol. 114 (3), pp. 281-9. Date of Electronic Publication: 2016 Jan 21.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hysterectomy*
Carcinoma, Endometrioid/*drug therapy
Endometrial Hyperplasia/*drug therapy
Endometrial Neoplasms/*drug therapy
Hypoglycemic Agents/*therapeutic use
Metformin/*therapeutic use
Aged ; Aged, 80 and over ; Blood Glucose/metabolism ; C-Peptide/metabolism ; Carcinoma, Endometrioid/metabolism ; Carcinoma, Endometrioid/pathology ; Endometrial Hyperplasia/metabolism ; Endometrial Hyperplasia/pathology ; Endometrial Neoplasms/metabolism ; Endometrial Neoplasms/pathology ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunohistochemistry ; Insulin/metabolism ; Insulin Resistance ; Ki-67 Antigen ; Middle Aged ; Myometrium/pathology ; Neoadjuvant Therapy ; Neoplasm Grading ; Neoplasm Invasiveness ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Preoperative Care ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications.
Autorzy :
Sivalingam VN; Institute of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.
Myers J; Institute of Human Development, Manchester Academic Health Science Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.
Nicholas S; Leeds Centre for Reproductive Medicine, Leeds Teaching Hospitals, Seacroft Hospital, Leeds LS14 6UH, UK.
Balen AH; Leeds Centre for Reproductive Medicine, Leeds Teaching Hospitals, Seacroft Hospital, Leeds LS14 6UH, UK.
Crosbie EJ; Institute of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK .
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Źródło :
Human reproduction update [Hum Reprod Update] 2014 Nov-Dec; Vol. 20 (6), pp. 853-68. Date of Electronic Publication: 2014 Jul 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genital Neoplasms, Female/*drug therapy
Hypoglycemic Agents/*therapeutic use
Metformin/*therapeutic use
Clomiphene/therapeutic use ; Diabetes, Gestational/drug therapy ; Endometrial Neoplasms/drug therapy ; Endometrial Neoplasms/prevention & control ; Female ; Genital Neoplasms, Female/prevention & control ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/pharmacology ; Insulin Resistance/physiology ; Life Style ; Metformin/adverse effects ; Metformin/pharmacology ; Ovulation/drug effects ; Ovulation Induction ; Polycystic Ovary Syndrome/drug therapy ; Pregnancy ; Pregnancy Outcome ; Pregnancy Rate ; Reproductive Health
Czasopismo naukowe
Tytuł :
Diagnosis and management of ectopic pregnancy.
Autorzy :
Sivalingam VN; Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, UK.
Duncan WC
Kirk E
Shephard LA
Horne AW
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Źródło :
The journal of family planning and reproductive health care [J Fam Plann Reprod Health Care] 2011 Oct; Vol. 37 (4), pp. 231-40. Date of Electronic Publication: 2011 Jul 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pregnancy, Ectopic*/blood
Pregnancy, Ectopic*/diagnostic imaging
Pregnancy, Ectopic*/drug therapy
Pregnancy, Ectopic*/surgery
Chorionic Gonadotropin, beta Subunit, Human/*blood
Methotrexate/*therapeutic use
Biomarkers/blood ; Female ; Humans ; Pregnancy ; Risk Factors ; Ultrasonography
Czasopismo naukowe
Tytuł :
Clinical diagnosis of fractures in a paediatric population.
Autorzy :
Al-Adhami AS; Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK.
Brennand CM
Chiam PP
Palmer EM
Schmieder TK
Shah AS
Sivalingam VN
Beattie TF
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Źródło :
European journal of emergency medicine : official journal of the European Society for Emergency Medicine [Eur J Emerg Med] 2005 Apr; Vol. 12 (2), pp. 99-101.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Emergency Medicine/*methods
Fractures, Bone/*diagnosis
Pediatrics/*methods
Child ; Edema/etiology ; Emergency Medicine/statistics & numerical data ; Female ; Fractures, Bone/complications ; Humans ; Logistic Models ; Male ; Pain/etiology ; Pain Measurement ; Pediatrics/statistics & numerical data ; Physical Examination/methods
Czasopismo naukowe
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